{"id":"https://openalex.org/W70595409","doi":null,"title":"Perineural infusion of 0.5% ropivacaine for successful treatment of phantom limb syndrome: a case report.","display_name":"Perineural infusion of 0.5% ropivacaine for successful treatment of phantom limb syndrome: a case report.","publication_year":2009,"publication_date":"2009-11-01","ids":{"openalex":"https://openalex.org/W70595409","mag":"70595409","pmid":"https://pubmed.ncbi.nlm.nih.gov/19881462"},"language":"en","primary_location":{"id":"pmid:19881462","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19881462","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva anestesiologica","raw_type":"Case Reports"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109319704","display_name":"Battista Borghi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121742","display_name":"Istituto Ortopedico Rizzoli","ror":"https://ror.org/02ycyys66","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210121742","https://openalex.org/I4210153126"]},{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"B Borghi","raw_affiliation_strings":["Department of Surgery and Anesthesiology Sciences, Research Unit of Anesthesia and Intensive Care, Rizzoli Orthopedic Institute, University of Bologna, Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Surgery and Anesthesiology Sciences, Research Unit of Anesthesia and Intensive Care, Rizzoli Orthopedic Institute, University of Bologna, Bologna, Italy","institution_ids":["https://openalex.org/I4210121742","https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085452504","display_name":"Stefano Bugamelli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Bugamelli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046293867","display_name":"Giuliana Stagni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Stagni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107836769","display_name":"M. Missiroli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Missiroli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019676251","display_name":"Robert J. Genco","orcid":"https://orcid.org/0000-0001-7604-506X","observed_orcids":["https://orcid.org/0000-0001-7604-506X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Genco","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5040379636","display_name":"Melissa Colizza","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M T Colizza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7726,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.75012019,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"75","issue":"11","first_page":"661","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11840","display_name":"Pain Management and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phantom-limb","display_name":"phantom limb","score":0.9909999966621399},{"id":"https://openalex.org/keywords/ropivacaine","display_name":"ropivacaine","score":0.9710000157356262},{"id":"https://openalex.org/keywords/perineural-catheter","display_name":"perineural catheter","score":0.7990000247955322},{"id":"https://openalex.org/keywords/sciatic-nerve","display_name":"sciatic nerve","score":0.6840000152587891},{"id":"https://openalex.org/keywords/complex-regional-pain-syndrome-type-ii","display_name":"complex regional pain syndrome type II","score":0.8899999856948853},{"id":"https://openalex.org/keywords/amputation-pain","display_name":"amputation pain","score":0.6290000081062317},{"id":"https://openalex.org/keywords/phantom-limb-pain","display_name":"phantom limb pain","score":0.6610000133514404},{"id":"https://openalex.org/keywords/phantom-limb-sensation","display_name":"phantom limb sensation","score":0.621999979019165},{"id":"https://openalex.org/keywords/local-anesthetic-infusion","display_name":"local anesthetic infusion","score":0.6389999985694885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9545960426330566},{"id":"https://openalex.org/C2776045273","wikidata":"https://www.wikidata.org/wiki/Q1202906","display_name":"Phantom pain","level":3,"score":0.8037869930267334},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6945693492889404},{"id":"https://openalex.org/C2780269707","wikidata":"https://www.wikidata.org/wiki/Q279504","display_name":"Ropivacaine","level":2,"score":0.6882771253585815},{"id":"https://openalex.org/C2781267111","wikidata":"https://www.wikidata.org/wiki/Q652297","display_name":"Catheter","level":2,"score":0.6426504254341125},{"id":"https://openalex.org/C2776204877","wikidata":"https://www.wikidata.org/wiki/Q477415","display_name":"Amputation","level":2,"score":0.6257559657096863},{"id":"https://openalex.org/C2777389121","wikidata":"https://www.wikidata.org/wiki/Q81225","display_name":"Morphine","level":2,"score":0.612272322177887},{"id":"https://openalex.org/C2776608144","wikidata":"https://www.wikidata.org/wiki/Q410352","display_name":"Gabapentin","level":3,"score":0.6058242917060852},{"id":"https://openalex.org/C2778100702","wikidata":"https://www.wikidata.org/wiki/Q1191062","display_name":"Phantom limb","level":3,"score":0.5463597774505615},{"id":"https://openalex.org/C68312169","wikidata":"https://www.wikidata.org/wiki/Q216685","display_name":"Orthopedic surgery","level":2,"score":0.4797045588493347},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4751703143119812},{"id":"https://openalex.org/C2779352459","wikidata":"https://www.wikidata.org/wiki/Q6031679","display_name":"Infusion therapy","level":2,"score":0.4687402844429016},{"id":"https://openalex.org/C2778994108","wikidata":"https://www.wikidata.org/wiki/Q1868462","display_name":"Local anesthetic","level":2,"score":0.44736623764038086},{"id":"https://openalex.org/C2986770162","wikidata":"https://www.wikidata.org/wiki/Q1191062","display_name":"Phantom limb pain","level":3,"score":0.43680340051651},{"id":"https://openalex.org/C2780226346","wikidata":"https://www.wikidata.org/wiki/Q1066311","display_name":"Complex regional pain syndrome","level":2,"score":0.4264669120311737},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000077212","descriptor_name":"Ropivacaine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077212","descriptor_name":"Ropivacaine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077212","descriptor_name":"Ropivacaine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000577","descriptor_name":"Amides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000577","descriptor_name":"Amides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000577","descriptor_name":"Amides","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000779","descriptor_name":"Anesthetics, Local","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000779","descriptor_name":"Anesthetics, Local","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000779","descriptor_name":"Anesthetics, Local","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007263","descriptor_name":"Infusions, Parenteral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007263","descriptor_name":"Infusions, Parenteral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007263","descriptor_name":"Infusions, Parenteral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010591","descriptor_name":"Phantom Limb","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010591","descriptor_name":"Phantom Limb","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D010591","descriptor_name":"Phantom Limb","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:19881462","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19881462","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Minerva anestesiologica","raw_type":"Case Reports"},{"id":"pmh:oai:cris.unibo.it:11585/85644","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11585/85644","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:70595409","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19881462","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.7799999713897705,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2325682294","https://openalex.org/W4403065235","https://openalex.org/W2119319574","https://openalex.org/W4251630782","https://openalex.org/W1902448826","https://openalex.org/W4236176709","https://openalex.org/W2106875791","https://openalex.org/W2469094202","https://openalex.org/W1970840613","https://openalex.org/W2033686457"],"abstract_inverted_index":{"Phantom":[0],"limb":[1,12,161,171],"syndrome":[2,59],"(PLS)":[3],"comprises":[4],"various":[5],"disturbances,":[6],"including":[7],"pain":[8,58,142],"in":[9,141],"the":[10,20,42,84,133,159,169,206,224,227,230,243],"missing":[11],"and":[13,69,95,111,151,201,229],"phantom":[14,160,170],"sensations.":[15,162],"This":[16],"study":[17],"is":[18],"about":[19],"successful":[21],"treatment":[22],"of":[23,30,49,72,79,166,226,233,245],"a":[24,34,50,105,138],"PLS":[25,92,207],"patient":[26,188,217],"by":[27],"prolonged":[28],"infusion":[29,71,114,125],"local":[31],"anesthetic":[32],"through":[33],"perineural":[35,106,177,185],"catheter.":[36],"A":[37],"45-year-old":[38],"man":[39],"came":[40],"to":[41,83,99,131,146,215,223,241],"Rizzoli":[43],"Orthopedic":[44],"Institute":[45],"(Bologna,":[46],"Italy)":[47],"complaining":[48],"painful":[51],"right":[52,87],"leg":[53],"after":[54,148,154,181],"trauma.":[55],"Complex":[56],"regional":[57],"(CRPS)":[60],"type":[61],"II":[62],"was":[63,74,96,109,122,126,143,179,189],"diagnosed.":[64],"Therapy":[65],"with":[66,115],"tricyclics,":[67],"gabapentin,":[68],"spinal":[70],"morphine":[73,192],"started.":[75,123],"After":[76,90,135,163],"4":[77],"years":[78],"treatment,":[80],"infection":[81],"led":[82],"need":[85],"for":[86],"below-the-knee":[88],"amputation.":[89],"amputation,":[91],"appeared":[93],"immediately":[94],"not":[97,209],"responsive":[98],"pharmacological":[100],"treatment.":[101],"At":[102],"day":[103],"II,":[104],"sciatic":[107],"catheter":[108,178],"positioned":[110],"0.5%":[112],"ropivacaine":[113],"an":[116],"elastomeric":[117],"pump":[118],"at":[119,197],"5":[120],"mL/h":[121],"The":[124,176,187,211],"temporarily":[127],"discontinued":[128],"every":[129],"week":[130],"evaluate":[132],"PLS.":[134],"7":[136],"days,":[137,150,156],"30%":[139],"reduction":[140],"observed,":[144],"increased":[145],"60%":[147],"14":[149],"disappeared":[152],"completely":[153],"21":[155],"leaving":[157],"only":[158],"28":[164],"days":[165],"continuous":[167],"infusion,":[168],"sensations":[172],"had":[173],"also":[174],"disappeared.":[175],"removed":[180],"48":[182],"hours":[183],"without":[184],"infusion.":[186],"weaned":[190],"from":[191],"over":[193],"150":[194],"days.":[195],"Follow-ups":[196],"6,":[198],"12,":[199],"24,":[200],"36":[202],"months":[203],"confirmed":[204],"that":[205],"did":[208],"reappear.":[210],"results":[212,232],"are":[213,219,238],"limited":[214],"one":[216],"but":[218],"encouraging,":[220],"particularly":[221],"due":[222],"relevance":[225],"pathology":[228],"poor":[231],"conventional":[234],"treatments.":[235],"More":[236],"cases":[237],"obviously":[239],"needed":[240],"support":[242],"efficacy":[244],"this":[246],"therapy.":[247]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-01T08:54:57.152042","created_date":"2016-06-24T00:00:00"}