{"id":"https://openalex.org/W7057324352","doi":null,"title":"INVESTIGATION OF PREFRONTAL AREAS IN VARIOUS ANIMAL TAXA USING DIFFUSION WEIGHTED IMAGING","display_name":"INVESTIGATION OF PREFRONTAL AREAS IN VARIOUS ANIMAL TAXA USING DIFFUSION WEIGHTED IMAGING","publication_year":null,"publication_date":null,"ids":{"openalex":"https://openalex.org/W7057324352"},"language":"en","primary_location":{"id":"pmh:oai:www.research.unipd.it:11577/3489973","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11577/3489973","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041396193","display_name":"Tommaso Gerussi","orcid":"https://orcid.org/0000-0003-0263-5635","observed_orcids":["https://orcid.org/0000-0003-0263-5635"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"GERUSSI, TOMMASO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5041396193"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/orbitofrontal-cortex","display_name":"orbitofrontal cortex","score":0.9570000171661377},{"id":"https://openalex.org/keywords/diffusion-weighted-imaging","display_name":"diffusion-weighted imaging","score":0.734000027179718},{"id":"https://openalex.org/keywords/constrained-spherical-deconvolution","display_name":"constrained spherical deconvolution","score":0.8379999995231628},{"id":"https://openalex.org/keywords/tractography","display_name":"tractography","score":0.8180000185966492},{"id":"https://openalex.org/keywords/sheep","display_name":"sheep","score":0.49300000071525574},{"id":"https://openalex.org/keywords/human","display_name":"human","score":0.671999990940094},{"id":"https://openalex.org/keywords/chimpanzees","display_name":"chimpanzees","score":0.996999979019165},{"id":"https://openalex.org/keywords/bottlenose-dolphin","display_name":"Tursiops truncatus","score":0.8429999947547913},{"id":"https://openalex.org/keywords/white-matter-connectivity","display_name":"white matter connectivity","score":0.38199999928474426},{"id":"https://openalex.org/keywords/comparative-neuroanatomy","display_name":"comparative neuroanatomy","score":0.5879999995231628},{"id":"https://openalex.org/keywords/nidopallium-caudolaterale","display_name":"nidopallium caudolaterale","score":0.7549999952316284},{"id":"https://openalex.org/keywords/ex-vivo-brain","display_name":"ex vivo brain","score":0.453000009059906}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5909000039100647},{"id":"https://openalex.org/C103378370","wikidata":"https://www.wikidata.org/wiki/Q948647","display_name":"Neuroanatomy","level":2,"score":0.5837000012397766},{"id":"https://openalex.org/C2781195155","wikidata":"https://www.wikidata.org/wiki/Q18680","display_name":"Prefrontal cortex","level":3,"score":0.5598000288009644},{"id":"https://openalex.org/C2776559556","wikidata":"https://www.wikidata.org/wiki/Q18717","display_name":"Orbitofrontal cortex","level":4,"score":0.5397999882698059},{"id":"https://openalex.org/C138673069","wikidata":"https://www.wikidata.org/wiki/Q322229","display_name":"Tracing","level":2,"score":0.4927000105381012},{"id":"https://openalex.org/C25876315","wikidata":"https://www.wikidata.org/wiki/Q15197465","display_name":"Neurochemical","level":2,"score":0.4722000062465668},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.44839999079704285},{"id":"https://openalex.org/C2777348757","wikidata":"https://www.wikidata.org/wiki/Q2346577","display_name":"Cortex (anatomy)","level":2,"score":0.4462999999523163},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3919999897480011},{"id":"https://openalex.org/C2993925342","wikidata":"https://www.wikidata.org/wiki/Q28457374","display_name":"Fiber tract","level":4,"score":0.3853999972343445},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37599998712539673},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.375900000333786},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.3628999888896942},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.36239999532699585},{"id":"https://openalex.org/C2780539906","wikidata":"https://www.wikidata.org/wiki/Q1422654","display_name":"Insular cortex","level":2,"score":0.35850000381469727},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.3499000072479248},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3262999951839447},{"id":"https://openalex.org/C2993056352","wikidata":"https://www.wikidata.org/wiki/Q7432","display_name":"Animal species","level":2,"score":0.31349998712539673},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.29429998993873596},{"id":"https://openalex.org/C2779089633","wikidata":"https://www.wikidata.org/wiki/Q4771426","display_name":"Anterograde tracing","level":3,"score":0.2930000126361847},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.26080000400543213},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.25679999589920044},{"id":"https://openalex.org/C50231774","wikidata":"https://www.wikidata.org/wiki/Q639842","display_name":"Brain mapping","level":2,"score":0.2547000050544739}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:www.research.unipd.it:11577/3489973","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/11577/3489973","pdf_url":null,"source":{"id":"https://openalex.org/S4306402547","display_name":"Padua Research Archive (University of Padova)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I138689650","host_organization_name":"University of Padua","host_organization_lineage":["https://openalex.org/I138689650"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2030183678","https://openalex.org/W4221016372","https://openalex.org/W2495839055","https://openalex.org/W4400056912","https://openalex.org/W2489912444","https://openalex.org/W4386399802","https://openalex.org/W7128528340","https://openalex.org/W2012305168","https://openalex.org/W2552367026","https://openalex.org/W3202828119"],"abstract_inverted_index":{"The":[0,483,529,546],"Prefrontal":[1],"Cortex":[2,197],"(PFC)":[3],"has":[4,44,167],"attracted":[5],"a":[6,103,157,220,228,341,351,420,553,564],"particular":[7,94],"interest":[8],"since":[9],"it":[10,43,142,177,206],"is":[11,63,130,143,178,306,437],"the":[12,24,34,37,41,66,132,140,195,200,210,213,231,235,245,264,303,310,325,328,331,358,398,401,406,411,428,435,438,445,453,457,461,466,474,491,503,510,521,535,540,568,573,581],"latest":[13],"developed":[14],"cortical":[15,304,332],"area":[16],"which":[17,62,570,578],"reached":[18],"its":[19,27],"apparent":[20],"maximum":[21],"development":[22],"in":[23,65,77,93,139,146,182,187,248,278,293,413,423,427,432,500],"human.":[25],"Although":[26],"name":[28],"came":[29],"from":[30,444,460],"mammalian":[31],"topography,":[32],"being":[33],"cortex":[35],"of":[36,40,90,199,209,230,280,330,375,410,441,468,512,520,567,584],"anterior":[38],"pole":[39],"brain,":[42,141],"been":[45,74,168,275,322],"shown":[46],"that":[47,208,238,431],"even":[48,353],"other":[49,79,91],"animals,":[50,425],"such":[51],"as":[52,257],"birds,":[53],"possessed":[54,263],"an":[55,518],"equivalent":[56],"region":[57],"called":[58,162,360,575],"Nidopallium":[59],"Caudolaterale":[60],"(NCL)":[61],"involved":[64],"same":[67,246],"functions.":[68],"These":[69],"multimodal":[70],"associative":[71],"areas":[72,232,561,569],"have":[73,273,321],"widely":[75],"studied":[76],"humans,":[78],"primates,":[80,260],"rodents":[81],"and":[82,100,118,124,152,176,204,212,217,223,252,296,298,317,389,405,463,476,481,493,506,514,525,542],"pigeons":[83],"through":[84,386],"several":[85,387],"techniques.":[86],"Nevertheless,":[87],"neuroanatomy":[88],"data":[89,294],"species,":[92],"on":[95,324,523,527,539],"fiber":[96,137,458],"connections,":[97],"are":[98,122,253],"scarce":[99],"would":[101],"deserve":[102],"deeper":[104],"attention,":[105],"especially":[106],"for":[107,112,135,267,419,495],"those":[108],"ones":[109],"largely":[110],"used":[111,145,452],"meat":[113],"products":[114],"(like":[115],"sheep,":[116],"cows":[117],"pigs)":[119],"whose":[120],"brains":[121,374],"wasted":[123],"poorly":[125],"investigated.":[126],"Even":[127],"though":[128],"tracing":[129,175,507],"considered":[131],"gold":[133],"standard":[134],"studying":[136],"connections":[138],"mostly":[144,289],"lab":[147],"animals":[148,241,272,302,586],"due":[149,290],"to":[150,170,174,234,291,346,371,455,532,580],"ethical":[151],"practical":[153],"reasons.":[154],"Despite":[155],"this,":[156],"relatively":[158],"recent":[159],"MRI":[160,356,408],"technique":[161,344],"Diffusion":[163],"Weighted":[164],"Imaging":[165],"(DWI)":[166],"proven":[169],"give":[171],"similar":[172],"results":[173,396,470],"applicable":[179],"not":[180,243,255,307,551],"only":[181,309,552],"in-vivo":[183],"specimens":[184],"but":[185,282,562],"also":[186,473,563],"fixed":[188],"ex-vivo":[189,414],"brains.":[190,415],"We":[191,381],"therefore":[192],"started":[193],"examining":[194],"Orbitofrontal":[196],"(OFC)":[198],"sheep":[201],"(Ovis":[202],"aries)":[203],"compared":[205],"with":[207,354,502,517],"human":[211],"chimpanzee.":[214],"While":[215],"histology":[216],"immunocytochemistry":[218],"revealed":[219],"different":[221,560],"cytoarchitectonic":[222],"neurochemical":[224],"structure,":[225],"DWI":[226,343],"showed":[227],"similarity":[229],"connected":[233],"OFC,":[236],"implying":[237],"although":[239],"these":[240,301,424,585],"do":[242],"show":[244],"subtlety":[247],"their":[249,496],"complex":[250,268,555],"behaviours":[251],"commonly":[254],"revered":[256],"\u201csmart\u201d":[258],"like":[259],"they":[261],"still":[262],"basic":[265],"structures":[266],"abstract":[269],"thought.":[270],"Farm":[271],"undoubtedly":[274],"insufficiently":[276],"examined":[277],"terms":[279],"neuroanatomy,":[281],"marine":[283],"mammals":[284,434],"certainly":[285],"share":[286],"this":[287,337],"neglect,":[288],"difficulty":[292],"collection":[295],"conservation,":[297],"ethics.":[299],"In":[300],"map":[305],"complete,":[308],"visual":[311],"(V1/V2),":[312],"auditory":[313],"(A1/A2),":[314],"motor":[315],"(MC)":[316],"somatosensory":[318],"(SSC)":[319],"cortices":[320,492],"localized":[323],"telencephalon":[326],"leaving":[327],"rest":[329],"surface":[333],"unassigned.":[334],"To":[335],"overcome":[336],"problem,":[338],"we":[339,417,451,464],"applied":[340,370],"new":[342,366],"able":[345],"detect":[347,456],"crossing":[348],"fibers":[349],"within":[350],"voxel":[352],"clinical":[355,407],"parameters,":[357,409],"so":[359,574],"constrained":[361],"spherical":[362],"deconvolution":[363],"(CSD).":[364],"This":[365],"mathematical":[367],"algorithm":[368],"was":[369,486],"three":[372],"formalin-fixed":[373],"adult":[376],"bottlenose":[377],"dolphin":[378],"(Tursiops":[379],"truncatus).":[380],"first":[382,490],"performed":[383],"global":[384],"tractography":[385],"steps":[388],"then":[390,487],"qualitatively":[391],"analysed":[392],"few":[393],"regions.":[394],"Our":[395],"confirmed":[397,509],"feasibility,":[399],"considering":[400],"long":[402],"fixation":[403],"time":[404],"CSD":[412,454],"Afterwards,":[416],"sought":[418],"putative":[421],"PFC":[422,436,537],"relying":[426],"general":[429],"concept":[430],"all":[433],"major":[439],"receiver":[440],"thalamic":[442,447,556],"inputs":[443],"mediodorsal":[446],"nucleus":[448],"(MD).":[449],"Therefore,":[450],"pathways":[459],"MD":[462,533],"proved":[465],"accuracy":[467],"our":[469],"by":[471],"seeding":[472,489],"lateral":[475],"medial":[477],"geniculate":[478],"nuclei":[479],"(LGN":[480],"MGN).":[482],"reverse":[484],"approach":[485],"applied,":[488],"look":[494],"related":[497,531],"tracts.":[498],"CSD,":[499],"accordance":[501],"previous":[504],"evoked-potential":[505],"studies,":[508],"location":[511,538],"A1/A2":[513,524],"V1/V2,":[515],"together":[516],"involvement":[519],"LGN":[522],"MGN":[526],"V1/V2.":[528],"tracts":[530],"detected":[534],"possible":[536],"orbital":[541],"cranial":[543],"temporal":[544],"lobes.":[545],"neocortical":[547],"pattern":[548],"thus":[549],"suggested":[550],"more":[554],"integration":[557],"arrangement":[558],"among":[559],"rostrolateral":[565],"rotation":[566],"probably":[571],"followed":[572],"telescoping":[576],"process":[577],"occurred":[579],"brain":[582],"case":[583],"during":[587],"evolution.":[588]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2025-10-10T00:00:00"}