{"id":"https://openalex.org/W7045117342","doi":null,"title":"Acute posterior cingulum integrity post-trauma prospectively predicts depression but not PTSD symptoms","display_name":"Acute posterior cingulum integrity post-trauma prospectively predicts depression but not PTSD symptoms","publication_year":2021,"publication_date":"2021-09-01","ids":{"openalex":"https://openalex.org/W7045117342"},"language":"en","primary_location":{"id":"pmh:oai:dc.uwm.edu:psych_facpubs-1014","doi":null,"is_oa":false,"landing_page_url":"https://dc.uwm.edu/psych_facpubs/15","pdf_url":null,"source":{"id":"https://openalex.org/S4377196567","display_name":"UWM Digital Commons (University of Wisconsin\u2013Milwaukee)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43579087","host_organization_name":"University of Wisconsin\u2013Milwaukee","host_organization_lineage":["https://openalex.org/I43579087"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Psychology Faculty Articles","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Weiss, Carissa N","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Weiss, Carissa N","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Huggins, Ashley A","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huggins, Ashley A","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059433442","display_name":"Tara A. Miskovich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Miskovich, Tara A","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018263271","display_name":"Jacklynn M. Fitzgerald","orcid":"https://orcid.org/0000-0002-6076-4067","observed_orcids":["https://orcid.org/0000-0002-6076-4067"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fitzgerald, Jacklynn M","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049707599","display_name":"Kenneth P. Bennett","orcid":"https://orcid.org/0000-0002-8023-3327","observed_orcids":["https://orcid.org/0000-0002-8023-3327"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bennett, Kenneth P","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103207668","display_name":"Jessica L. Krukowski","orcid":"https://orcid.org/0000-0003-1921-7480","observed_orcids":["https://orcid.org/0000-0003-1921-7480"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Krukowski, Jessica L","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Webb, E Kate","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Webb, E Kate","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048451334","display_name":"Terri A. deRoon\u2010Cassini","orcid":"https://orcid.org/0000-0002-9485-0625","observed_orcids":["https://orcid.org/0000-0002-9485-0625"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"deRoon-Cassini, Terri A","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5058723175","display_name":"Christine L. Larson","orcid":"https://orcid.org/0000-0002-1359-6080","observed_orcids":["https://orcid.org/0000-0002-1359-6080"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Larson, Christine L","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.41592128,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10242","display_name":"Posttraumatic Stress Disorder Research","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.019700000062584877,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/posttraumatic-stress-disorder","display_name":"post-traumatic stress disorder","score":0.8330000042915344},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.4129999876022339},{"id":"https://openalex.org/keywords/white-matter-integrity","display_name":"white matter integrity","score":0.753000020980835},{"id":"https://openalex.org/keywords/anterior-cingulum","display_name":"anterior cingulum","score":0.8119999766349792},{"id":"https://openalex.org/keywords/fractional-anisotropy","display_name":"fractional anisotropy","score":0.9110000133514404},{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.8029999732971191},{"id":"https://openalex.org/keywords/diffusion-weighted-imaging","display_name":"diffusion-weighted imaging","score":0.7200000286102295},{"id":"https://openalex.org/keywords/trauma-resilience","display_name":"trauma resilience","score":0.5040000081062317},{"id":"https://openalex.org/keywords/uncinate-fasciculus","display_name":"uncinate fasciculus","score":0.7570000290870667},{"id":"https://openalex.org/keywords/corpus-callosum","display_name":"corpus callosum","score":0.9929999709129333},{"id":"https://openalex.org/keywords/acute-trauma","display_name":"acute trauma","score":0.3449999988079071}],"concepts":[{"id":"https://openalex.org/C2777193593","wikidata":"https://www.wikidata.org/wiki/Q15130814","display_name":"Cingulum (brain)","level":5,"score":0.8726000189781189},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.8144999742507935},{"id":"https://openalex.org/C2779490353","wikidata":"https://www.wikidata.org/wiki/Q176007","display_name":"Uncinate fasciculus","level":5,"score":0.6848000288009644},{"id":"https://openalex.org/C2778183499","wikidata":"https://www.wikidata.org/wiki/Q223851","display_name":"Corpus callosum","level":2,"score":0.6251999735832214},{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.609499990940094},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.5978999733924866},{"id":"https://openalex.org/C89916169","wikidata":"https://www.wikidata.org/wiki/Q17014600","display_name":"Fractional anisotropy","level":4,"score":0.5773000121116638},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5702000260353088},{"id":"https://openalex.org/C2776191500","wikidata":"https://www.wikidata.org/wiki/Q2123166","display_name":"Leukoaraiosis","level":4,"score":0.4925999939441681},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.44449999928474426},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.4214000105857849},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.35179999470710754},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3499000072479248},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.33009999990463257},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3253999948501587},{"id":"https://openalex.org/C2778159538","wikidata":"https://www.wikidata.org/wiki/Q16920843","display_name":"Traumatic stress","level":2,"score":0.32440000772476196},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.32330000400543213},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3149000108242035},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.3052999973297119},{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.298799991607666},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.2874999940395355},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.2777999937534332},{"id":"https://openalex.org/C198433322","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value of tests","level":2,"score":0.2759000062942505},{"id":"https://openalex.org/C17624336","wikidata":"https://www.wikidata.org/wiki/Q461644","display_name":"Glasgow Coma Scale","level":2,"score":0.275299996137619},{"id":"https://openalex.org/C2780830986","wikidata":"https://www.wikidata.org/wiki/Q6029363","display_name":"Inferior longitudinal fasciculus","level":5,"score":0.2637999951839447},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.2572000026702881},{"id":"https://openalex.org/C2780724011","wikidata":"https://www.wikidata.org/wiki/Q1295316","display_name":"Emergency department","level":2,"score":0.2515999972820282},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.24269999563694},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.24150000512599945},{"id":"https://openalex.org/C2779281540","wikidata":"https://www.wikidata.org/wiki/Q5062122","display_name":"Central nervous system disease","level":2,"score":0.24140000343322754},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.23770000040531158},{"id":"https://openalex.org/C2991847609","wikidata":"https://www.wikidata.org/wiki/Q202387","display_name":"Posttraumatic stress","level":2,"score":0.2176000028848648},{"id":"https://openalex.org/C2910140627","wikidata":"https://www.wikidata.org/wiki/Q424221","display_name":"Acute Stress Disorder","level":3,"score":0.21529999375343323},{"id":"https://openalex.org/C2776317618","wikidata":"https://www.wikidata.org/wiki/Q544006","display_name":"Anxiety disorder","level":3,"score":0.2143000066280365},{"id":"https://openalex.org/C190385971","wikidata":"https://www.wikidata.org/wiki/Q373494","display_name":"Injury prevention","level":3,"score":0.20489999651908875},{"id":"https://openalex.org/C2781210436","wikidata":"https://www.wikidata.org/wiki/Q1892702","display_name":"Cingulate cortex","level":3,"score":0.20010000467300415},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.19779999554157257},{"id":"https://openalex.org/C2984185122","wikidata":"https://www.wikidata.org/wiki/Q1309431","display_name":"Structural integrity","level":2,"score":0.1973000019788742},{"id":"https://openalex.org/C2994141250","wikidata":"https://www.wikidata.org/wiki/Q193078","display_name":"Traumatic injury","level":2,"score":0.19460000097751617},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.19200000166893005}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:dc.uwm.edu:psych_facpubs-1014","doi":null,"is_oa":false,"landing_page_url":"https://dc.uwm.edu/psych_facpubs/15","pdf_url":null,"source":{"id":"https://openalex.org/S4377196567","display_name":"UWM Digital Commons (University of Wisconsin\u2013Milwaukee)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43579087","host_organization_name":"University of Wisconsin\u2013Milwaukee","host_organization_lineage":["https://openalex.org/I43579087"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Psychology Faculty Articles","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3201772630","https://openalex.org/W6997306154","https://openalex.org/W2946527469","https://openalex.org/W2007304263","https://openalex.org/W2097343787","https://openalex.org/W2777428103","https://openalex.org/W1992436988","https://openalex.org/W2121117025","https://openalex.org/W2073426010","https://openalex.org/W2050239606"],"abstract_inverted_index":{"Background:":[0],"Little":[1],"is":[2,204,227],"known":[3],"about":[4],"what":[5],"distinguishes":[6],"those":[7,14],"who":[8],"are":[9],"resilient":[10],"after":[11,202,241],"trauma":[12,61,82,120,203],"from":[13],"at":[15,136,196],"risk":[16],"for":[17,109,149],"developing":[18],"posttraumatic":[19],"stress":[20],"disorder":[21],"(PTSD).":[22],"Previous":[23],"work":[24],"indicates":[25],"white":[26,46,74,175,199,222,230],"matter":[27,47,75,176,200,223,231],"integrity":[28,43,76,103,201,224],"may":[29,233],"be":[30,235],"a":[31,90,117,187],"useful":[32],"biomarker":[33],"in":[34,41,77,89,104,112,186,237],"predicting":[35],"PTSD.":[36],"Research":[37],"has":[38],"shown":[39],"changes":[40],"the":[42,58,70,78,96,113,144,209,218,238],"of":[44,60,73,81,116,211,220],"three":[45],"tracts\u2014the":[48],"cingulum":[49,160],"bundle,":[50],"corpus":[51],"callosum":[52],"(CC),":[53],"and":[54,131,139,225],"uncinate":[55],"fasciculus":[56],"(UNC)\u2014in":[57],"aftermath":[59,80],"relate":[62],"to":[63,83,167,180,208],"PTSD":[64,86,147,171,181,194,213,226],"symptoms.":[65,172,214],"However,":[66],"few":[67],"have":[68],"examined":[69],"predictive":[71],"utility":[72],"acute":[79,100,198,239],"predict":[84],"prospective":[85],"symptom":[87],"severity":[88],"mixed":[91],"traumatic":[92,110],"injury":[93],"sample.\\nMethod:":[94],"Thus,":[95],"current":[97],"study":[98],"investigated":[99],"brain":[101],"structural":[102],"148":[105],"individuals":[106],"being":[107],"treated":[108],"injuries":[111],"Emergency":[114],"Department":[115],"Level":[118],"1":[119],"center.":[121],"Participants":[122],"underwent":[123],"diffusion-weighted":[124],"magnetic":[125],"resonance":[126],"imaging":[127],"2":[128],"weeks":[129],"post-trauma":[130],"completed":[132],"several":[133],"self-report":[134],"measures":[135],"2-weeks":[137],"(T1)":[138],"6":[140],"months":[141],"(T2),":[142],"including":[143],"Clinician":[145],"Administered":[146],"Scale":[148],"DSM-V":[150],"(CAPS-5),":[151],"post-injury.\\nResults:":[152],"Consistent":[153],"with":[154,191],"previous":[155],"work,":[156],"T1":[157],"lesser":[158],"anterior":[159],"fractional":[161],"anisotropy":[162],"(FA)":[163],"was":[164],"marginally":[165],"related":[166,179,207],"greater":[168],"T2":[169],"total":[170],"No":[173],"other":[174],"tracts":[177],"were":[178],"symptoms.\\nConclusions:":[182],"Results":[183],"demonstrate":[184],"that":[185],"traumatically":[188],"injured":[189],"sample":[190],"predominantly":[192],"subclinical":[193],"symptoms":[195],"T2,":[197],"not":[205,234],"robustly":[206],"development":[210],"chronic":[212],"These":[215],"findings":[216],"suggest":[217],"timing":[219],"evaluating":[221],"important":[228],"as":[229],"differences":[232],"apparent":[236],"period":[240],"injury.":[242]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2025-10-10T00:00:00"}