{"id":"https://openalex.org/W7034174","doi":null,"title":"Thrombosis and the Pill.","display_name":"Thrombosis and the Pill.","publication_year":1970,"publication_date":"1970-02-01","ids":{"openalex":"https://openalex.org/W7034174","mag":"7034174","pmid":"https://pubmed.ncbi.nlm.nih.gov/12254686"},"language":"en","primary_location":{"id":"pmid:12254686","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12254686","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Prescribers' journal","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105416388","display_name":"Martin P. Vessey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"M P Vessey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5105416388"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.6117,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.85798567,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"10","issue":"1","first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10600","display_name":"Reproductive Health and Contraception","score":0.04019999876618385,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-contraceptives","display_name":"oral contraceptives","score":0.9879999756813049},{"id":"https://openalex.org/keywords/thrombosis","display_name":"thrombosis","score":0.8679999709129333},{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.9190000295639038},{"id":"https://openalex.org/keywords/superficial-venous-thrombosis","display_name":"superficial thrombophlebitis","score":0.8980000019073486},{"id":"https://openalex.org/keywords/cerebral-thrombosis","display_name":"cerebral thrombosis","score":0.949999988079071},{"id":"https://openalex.org/keywords/coronary-thrombosis","display_name":"coronary thrombosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/estrogen-dose","display_name":"estrogen dose","score":0.8009999990463257},{"id":"https://openalex.org/keywords/sequential-oral-contraceptives","display_name":"sequential oral contraceptives","score":0.722000002861023},{"id":"https://openalex.org/keywords/combined-oral-contraceptives","display_name":"combined oral contraceptives","score":0.9679999947547913},{"id":"https://openalex.org/keywords/thromboembolic-risk","display_name":"thromboembolic risk","score":0.7879999876022339},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.8270000219345093}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9136452078819275},{"id":"https://openalex.org/C81603835","wikidata":"https://www.wikidata.org/wiki/Q3457430","display_name":"Pill","level":2,"score":0.8968515396118164},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.5795377492904663},{"id":"https://openalex.org/C2779076696","wikidata":"https://www.wikidata.org/wiki/Q1280670","display_name":"Family planning","level":4,"score":0.5569370985031128},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5370956659317017},{"id":"https://openalex.org/C160050368","wikidata":"https://www.wikidata.org/wiki/Q132453","display_name":"Developed country","level":3,"score":0.5030567049980164},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.4985795021057129},{"id":"https://openalex.org/C2776149422","wikidata":"https://www.wikidata.org/wiki/Q377978","display_name":"Thrombophlebitis","level":3,"score":0.4852321147918701},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4165027439594269},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.34535491466522217},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2031521201133728},{"id":"https://openalex.org/C2986817661","wikidata":"https://www.wikidata.org/wiki/Q185698","display_name":"Research methodology","level":3,"score":0.1614862084388733},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.13406559824943542},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001777","descriptor_name":"Blood Coagulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003267","descriptor_name":"Contraception","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003276","descriptor_name":"Contraceptives, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003277","descriptor_name":"Contraceptives, Oral, Combined","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003278","descriptor_name":"Contraceptives, Oral, Hormonal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003625","descriptor_name":"Data Collection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004194","descriptor_name":"Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004617","descriptor_name":"Embolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005193","descriptor_name":"Family Planning Services","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012106","descriptor_name":"Research","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012494","descriptor_name":"Sampling Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013923","descriptor_name":"Thromboembolism","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013924","descriptor_name":"Thrombophlebitis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014652","descriptor_name":"Vascular Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:12254686","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12254686","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Prescribers' journal","raw_type":"Journal Article"},{"id":"mag:7034174","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12254686","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1998832164","https://openalex.org/W2209008703","https://openalex.org/W4301951299","https://openalex.org/W2735040446","https://openalex.org/W2068178626","https://openalex.org/W2254686142","https://openalex.org/W2413701745","https://openalex.org/W2052245102","https://openalex.org/W2420975","https://openalex.org/W2185666523"],"abstract_inverted_index":{"The":[0,82,118,134,247],"results":[1],"of":[2,9,12,31,43,75,79,84,91,108,116,139,147,149,153,170,195,210,222,236,250],"3":[3,36],"British":[4,22,135],"and":[5,51,62,78,220,238,252],"1":[6,21],"American":[7,86,119],"investigation":[8],"the":[10,29,85,92,99,106,145,158,180,191,198,211,223,233,244],"risk":[11,30,101,160],"thromboembolism":[13,77],"among":[14,25,39,173],"women":[15],"using":[16],"oral":[17,60,187,257],"contraceptives":[18,61,258],"are":[19],"reviewed.":[20],"study":[23,87,120],"conducted":[24],"general":[26],"practitioners":[27],"found":[28,55],"developing":[32],"superficial":[33],"thrombophlebitis":[34],"about":[35],"times":[37],"greater":[38,103,248],"pill":[40,212],"users.":[41],"Neither":[42],"2":[44],"other":[45,214],"studies,":[46],"in":[47,73,105],"which":[48],"hospital":[49],"admissions":[50],"fatalities":[52],"were":[53,88],"analyzed,":[54],"any":[56,96,184],"significant":[57],"link":[58],"between":[59],"coronary":[63],"thrombosis,":[64],"but":[65],"both":[66],"indicated":[67],"a":[68],"6":[69],"to":[70,189],"8-fold":[71],"increase":[72],"risks":[74,199,249],"venous":[76],"cerebral":[80],"thrombosis.":[81],"findings":[83],"similar.":[89],"None":[90],"4":[93],"studies":[94],"discovered":[95],"evidence":[97,123,230],"that":[98,111,124,157,232],"thromboembolic":[100,159,245],"is":[102,161,207,226,241],"early":[104],"course":[107],"medication":[109],"or,":[110],"it":[112],"increases":[113],"with":[114,163],"duration":[115],"use.":[117],"obtained":[121],"some":[122],"sequential":[125,239],"preparations":[126],"might":[127],"be":[128,190,201],"more":[129,169],"harmful":[130],"than":[131,172],"combined":[132,237],"ones.":[133],"Committee":[136],"on":[137,144],"Safety":[138],"Drugs":[140],"has":[141],"since":[142],"determined,":[143],"basis":[146],"analysis":[148],"routinely":[150],"submitted":[151],"reports":[152],"suspected":[154],"adverse":[155],"reactions,":[156],"higher":[162],"pills":[164,240],"containing":[165,175],"75":[166],"mcg":[167],"or":[168],"estrogen":[171],"those":[174],"only":[176,192],"50":[177],"mcg.":[178],"For":[179],"woman,":[181],"who":[182],"for":[183,243],"reason":[185],"finds":[186],"contraception":[188],"satisfactory":[193],"method":[194],"birth":[196],"control,":[197],"may":[200,259],"considered":[202],"acceptable":[203],"provided":[204],"medical":[205],"supervision":[206],"adequate.":[208],"Use":[209],"entails":[213],"known":[215],"major":[216],"hazards":[217],"(jaundice,":[218],"hypertension)":[219],"knowledge":[221],"longterm":[224],"effects":[225],"very":[227],"incomplete.":[228],"Substantial":[229],"suggests":[231],"estrogenic":[234],"component":[235],"responsible":[242],"risks.":[246],"pregnancy":[251],"menstrual":[253],"disturbances":[254],"accompanying":[255],"progestogen-only":[256],"limit":[260],"their":[261],"advantages.":[262]},"counts_by_year":[{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}