{"id":"https://openalex.org/W7018529362","doi":null,"title":"The Crossroad of Phosphatase and Kinase Signaling in Cancer","display_name":"The Crossroad of Phosphatase and Kinase Signaling in Cancer","publication_year":2020,"publication_date":"2020-11-26","ids":{"openalex":"https://openalex.org/W7018529362"},"language":"en","primary_location":{"id":"pmh:oai:repub.eur.nl:132400","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/132400","pdf_url":"http://repub.eur.nl/pub/132400","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://repub.eur.nl/pub/132400","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Sousa Faria, Alessandra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sousa Faria, Alessandra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12104","display_name":"Protein Tyrosine Phosphatases","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13779","display_name":"Cancer Mechanisms and Therapy","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-tyrosine-phosphatase","display_name":"protein tyrosine phosphatase","score":0.9010000228881836},{"id":"https://openalex.org/keywords/protein-kinases","display_name":"protein kinases","score":0.7990000247955322},{"id":"https://openalex.org/keywords/cancer-signaling","display_name":"cancer signaling","score":0.8370000123977661},{"id":"https://openalex.org/keywords/phosphorylation","display_name":"phosphorylation","score":0.9049999713897705},{"id":"https://openalex.org/keywords/targeted-therapy","display_name":"targeted therapy","score":0.6019999980926514},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.7490000128746033},{"id":"https://openalex.org/keywords/tumor-recurrence","display_name":"tumor recurrence","score":0.9210000038146973},{"id":"https://openalex.org/keywords/kinase-inhibitors","display_name":"kinase inhibitors","score":0.7440000176429749},{"id":"https://openalex.org/keywords/cell-cycle-inhibitors","display_name":"cell cycle inhibitors","score":0.7409999966621399}],"concepts":[{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6036999821662903},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5748999714851379},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.5741000175476074},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.5652999877929688},{"id":"https://openalex.org/C178666793","wikidata":"https://www.wikidata.org/wiki/Q422476","display_name":"Phosphatase","level":3,"score":0.5533000230789185},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5192000269889832},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4596000015735626},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.40310001373291016},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.3720000088214874},{"id":"https://openalex.org/C2776321633","wikidata":"https://www.wikidata.org/wiki/Q7187557","display_name":"Phosphoric monoester hydrolases","level":4,"score":0.3610999882221222},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3151000142097473},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.30799999833106995},{"id":"https://openalex.org/C150555746","wikidata":"https://www.wikidata.org/wiki/Q210973","display_name":"Cell signaling","level":3,"score":0.30239999294281006},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2904999852180481},{"id":"https://openalex.org/C42362537","wikidata":"https://www.wikidata.org/wiki/Q87099740","display_name":"Tyrosine kinase","level":3,"score":0.28519999980926514},{"id":"https://openalex.org/C137361374","wikidata":"https://www.wikidata.org/wiki/Q6714442","display_name":"MAP kinase kinase kinase","level":4,"score":0.2818000018596649},{"id":"https://openalex.org/C155985219","wikidata":"https://www.wikidata.org/wiki/Q409325","display_name":"Extracellular signal-regulated kinases","level":4,"score":0.27880001068115234},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.27730000019073486},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.2745000123977661},{"id":"https://openalex.org/C389152","wikidata":"https://www.wikidata.org/wiki/Q6593007","display_name":"Protein phosphatase 2","level":4,"score":0.2694000005722046},{"id":"https://openalex.org/C97920573","wikidata":"https://www.wikidata.org/wiki/Q17915102","display_name":"DUSP6","level":5,"score":0.2567000091075897},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.251800000667572}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:repub.eur.nl:132400","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/132400","pdf_url":"http://repub.eur.nl/pub/132400","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:eur:oai:pure.eur.nl:publications/6526eed6-2746-411d-b623-4ea4510e5897","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/6526eed6-2746-411d-b623-4ea4510e5897","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:eur:oai:repub.eur.nl:132400","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/132400","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"}],"best_oa_location":{"id":"pmh:oai:repub.eur.nl:132400","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/132400","pdf_url":"http://repub.eur.nl/pub/132400","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3202489485","display_name":"InGrowth, biomimetic product developed by platelet bioactivation platform: applications in the veterinary and research and development areas","funder_award_id":"17/26317-1","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G4402799499","display_name":null,"funder_award_id":"2015/","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G4470102072","display_name":null,"funder_award_id":"2018/00736-0","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G5520373576","display_name":"Low molecular weight protein tyrosine phosphatase in colorectal cancer: from the bench to product generation","funder_award_id":"15/20412-7","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G5902659572","display_name":null,"funder_award_id":"2017/08119-8","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"},{"id":"https://openalex.org/G8919019373","display_name":"Human platelet lysate: from discard to value products in cell therapy and advanced cell-based medicine","funder_award_id":"16/14459-3","funder_id":"https://openalex.org/F4320320997","funder_display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo"}],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7018529362.pdf","grobid_xml":"https://content.openalex.org/works/W7018529362.grobid-xml"},"referenced_works_count":421,"referenced_works":["https://openalex.org/W157490795","https://openalex.org/W191921287","https://openalex.org/W196385150","https://openalex.org/W242378800","https://openalex.org/W747719605","https://openalex.org/W1487264337","https://openalex.org/W1511482735","https://openalex.org/W1520425169","https://openalex.org/W1522760404","https://openalex.org/W1524236940","https://openalex.org/W1528151187","https://openalex.org/W1578364075","https://openalex.org/W1578783749","https://openalex.org/W1602144231","https://openalex.org/W1603593294","https://openalex.org/W1605655296","https://openalex.org/W1608780962","https://openalex.org/W1682825171","https://openalex.org/W1766122222","https://openalex.org/W1777600820","https://openalex.org/W1789274326","https://openalex.org/W1821541324","https://openalex.org/W1825327969","https://openalex.org/W1907043515","https://openalex.org/W1935876833","https://openalex.org/W1944981637","https://openalex.org/W1949250268","https://openalex.org/W1952327286","https://openalex.org/W1963549684","https://openalex.org/W1965112825","https://openalex.org/W1969277972","https://openalex.org/W1969342647","https://openalex.org/W1969448148","https://openalex.org/W1969653234","https://openalex.org/W1970915933","https://openalex.org/W1971124929","https://openalex.org/W1971427516","https://openalex.org/W1971697388","https://openalex.org/W1972402405","https://openalex.org/W1972794464","https://openalex.org/W1976036895","https://openalex.org/W1976954262","https://openalex.org/W1978714931","https://openalex.org/W1979061661","https://openalex.org/W1979845766","https://openalex.org/W1980148430","https://openalex.org/W1981243382","https://openalex.org/W1981790872","https://openalex.org/W1982102430","https://openalex.org/W1982134242","https://openalex.org/W1982577346","https://openalex.org/W1983117189","https://openalex.org/W1983593583","https://openalex.org/W1985870014","https://openalex.org/W1986573898","https://openalex.org/W1990341278","https://openalex.org/W1990561391","https://openalex.org/W1990770540","https://openalex.org/W1990985423","https://openalex.org/W1992139821","https://openalex.org/W1992598400","https://openalex.org/W1993161002","https://openalex.org/W1993436029","https://openalex.org/W1993591358","https://openalex.org/W1993643473","https://openalex.org/W1993908542","https://openalex.org/W1994370838","https://openalex.org/W1996339229","https://openalex.org/W1996765015","https://openalex.org/W1996888275","https://openalex.org/W1998192298","https://openalex.org/W1999328539","https://openalex.org/W1999403270","https://openalex.org/W2000138631","https://openalex.org/W2001768618","https://openalex.org/W2003676289","https://openalex.org/W2004016651","https://openalex.org/W2006145456","https://openalex.org/W2007086823","https://openalex.org/W2009610571","https://openalex.org/W2010954749","https://openalex.org/W2013692136","https://openalex.org/W2016547769","https://openalex.org/W2016741520","https://openalex.org/W2018038784","https://openalex.org/W2018209127","https://openalex.org/W2019937162","https://openalex.org/W2021225408","https://openalex.org/W2023902889","https://openalex.org/W2025341690","https://openalex.org/W2025959778","https://openalex.org/W2026198465","https://openalex.org/W2026298111","https://openalex.org/W2028179512","https://openalex.org/W2030665169","https://openalex.org/W2030694827","https://openalex.org/W2031307165","https://openalex.org/W2033577946","https://openalex.org/W2034413738","https://openalex.org/W2035028977","https://openalex.org/W2036130486","https://openalex.org/W2036941010","https://openalex.org/W2038254116","https://openalex.org/W2038405639","https://openalex.org/W2038938133","https://openalex.org/W2040527329","https://openalex.org/W2040663231","https://openalex.org/W2041414354","https://openalex.org/W2041991976","https://openalex.org/W2043820795","https://openalex.org/W2044304412","https://openalex.org/W2044358964","https://openalex.org/W2044947105","https://openalex.org/W2046589593","https://openalex.org/W2047920951","https://openalex.org/W2048284951","https://openalex.org/W2049387039","https://openalex.org/W2050017957","https://openalex.org/W2050701385","https://openalex.org/W2050839616","https://openalex.org/W2052205473","https://openalex.org/W2052812111","https://openalex.org/W2053305824","https://openalex.org/W2053465902","https://openalex.org/W2054710204","https://openalex.org/W2054738316","https://openalex.org/W2055085422","https://openalex.org/W2055281063","https://openalex.org/W2055807959","https://openalex.org/W2056370224","https://openalex.org/W2056525663","https://openalex.org/W2056818014","https://openalex.org/W2057200599","https://openalex.org/W2057637682","https://openalex.org/W2058067037","https://openalex.org/W2058897537","https://openalex.org/W2059649891","https://openalex.org/W2060312432","https://openalex.org/W2061049714","https://openalex.org/W2061640328","https://openalex.org/W2062892961","https://openalex.org/W2063062036","https://openalex.org/W2063316140","https://openalex.org/W2064162418","https://openalex.org/W2064783045","https://openalex.org/W2065159330","https://openalex.org/W2065965392","https://openalex.org/W2067414711","https://openalex.org/W2067776712","https://openalex.org/W2068566873","https://openalex.org/W2069519394","https://openalex.org/W2070297221","https://openalex.org/W2070642821","https://openalex.org/W2071432356","https://openalex.org/W2072275141","https://openalex.org/W2072697288","https://openalex.org/W2075363343","https://openalex.org/W2076341305","https://openalex.org/W2077146974","https://openalex.org/W2078328099","https://openalex.org/W2078491934","https://openalex.org/W2078824603","https://openalex.org/W2079139779","https://openalex.org/W2079145414","https://openalex.org/W2079490523","https://openalex.org/W2079508686","https://openalex.org/W2079629625","https://openalex.org/W2079660420","https://openalex.org/W2083123438","https://openalex.org/W2084383114","https://openalex.org/W2085057506","https://openalex.org/W2085289502","https://openalex.org/W2085334497","https://openalex.org/W2087118276","https://openalex.org/W2087972256","https://openalex.org/W2088007882","https://openalex.org/W2089194978","https://openalex.org/W2093506975","https://openalex.org/W2093717184","https://openalex.org/W2094615952","https://openalex.org/W2096045656","https://openalex.org/W2097221124","https://openalex.org/W2098377388","https://openalex.org/W2098388378","https://openalex.org/W2101821060","https://openalex.org/W2102084873","https://openalex.org/W2103079623","https://openalex.org/W2103558787","https://openalex.org/W2103888323","https://openalex.org/W2108444995","https://openalex.org/W2111485605","https://openalex.org/W2111563106","https://openalex.org/W2112167480","https://openalex.org/W2113020324","https://openalex.org/W2113180795","https://openalex.org/W2113515869","https://openalex.org/W2114629504","https://openalex.org/W2114917163","https://openalex.org/W2115040301","https://openalex.org/W2115420863","https://openalex.org/W2119278581","https://openalex.org/W2121511357","https://openalex.org/W2121532361","https://openalex.org/W2125499510","https://openalex.org/W2125870327","https://openalex.org/W2126525177","https://openalex.org/W2128139337","https://openalex.org/W2128180360","https://openalex.org/W2129290564","https://openalex.org/W2133210615","https://openalex.org/W2133306113","https://openalex.org/W2134234801","https://openalex.org/W2134884900","https://openalex.org/W2135359106","https://openalex.org/W2135975711","https://openalex.org/W2137009864","https://openalex.org/W2137997760","https://openalex.org/W2138088600","https://openalex.org/W2139910235","https://openalex.org/W2141444154","https://openalex.org/W2142337877","https://openalex.org/W2142567247","https://openalex.org/W2142845200","https://openalex.org/W2143075183","https://openalex.org/W2143736243","https://openalex.org/W2145137278","https://openalex.org/W2146832883","https://openalex.org/W2149266461","https://openalex.org/W2150541721","https://openalex.org/W2151645507","https://openalex.org/W2156558755","https://openalex.org/W2157201048","https://openalex.org/W2157820287","https://openalex.org/W2163502506","https://openalex.org/W2164288583","https://openalex.org/W2164464893","https://openalex.org/W2164670366","https://openalex.org/W2166544217","https://openalex.org/W2167610544","https://openalex.org/W2168817541","https://openalex.org/W2169481463","https://openalex.org/W2170816569","https://openalex.org/W2170975933","https://openalex.org/W2171874387","https://openalex.org/W2176808582","https://openalex.org/W2182856073","https://openalex.org/W2201007235","https://openalex.org/W2223535266","https://openalex.org/W2255483315","https://openalex.org/W2255703111","https://openalex.org/W2259176485","https://openalex.org/W2259282515","https://openalex.org/W2261453315","https://openalex.org/W2269814587","https://openalex.org/W2274064875","https://openalex.org/W2286633180","https://openalex.org/W2292011126","https://openalex.org/W2292508768","https://openalex.org/W2295014892","https://openalex.org/W2301434366","https://openalex.org/W2312557113","https://openalex.org/W2318488087","https://openalex.org/W2332572711","https://openalex.org/W2334957133","https://openalex.org/W2335037156","https://openalex.org/W2348480799","https://openalex.org/W2387313945","https://openalex.org/W2395612161","https://openalex.org/W2404846360","https://openalex.org/W2410975830","https://openalex.org/W2412688330","https://openalex.org/W2417524082","https://openalex.org/W2474073575","https://openalex.org/W2489819398","https://openalex.org/W2509304917","https://openalex.org/W2513996650","https://openalex.org/W2520404264","https://openalex.org/W2557133906","https://openalex.org/W2557279504","https://openalex.org/W2572665863","https://openalex.org/W2586263396","https://openalex.org/W2586743405","https://openalex.org/W2587770349","https://openalex.org/W2589062331","https://openalex.org/W2589766093","https://openalex.org/W2591359967","https://openalex.org/W2595170317","https://openalex.org/W2600402823","https://openalex.org/W2601291486","https://openalex.org/W2602267834","https://openalex.org/W2606059677","https://openalex.org/W2610786733","https://openalex.org/W2613430165","https://openalex.org/W2616983128","https://openalex.org/W2619482403","https://openalex.org/W2619934268","https://openalex.org/W2724874687","https://openalex.org/W2725432218","https://openalex.org/W2731227355","https://openalex.org/W2735168556","https://openalex.org/W2738578753","https://openalex.org/W2746061356","https://openalex.org/W2748853610","https://openalex.org/W2748990043","https://openalex.org/W2749725594","https://openalex.org/W2749938292","https://openalex.org/W2757120387","https://openalex.org/W2759033938","https://openalex.org/W2763714610","https://openalex.org/W2767408720","https://openalex.org/W2768112975","https://openalex.org/W2781121168","https://openalex.org/W2781650509","https://openalex.org/W2782675598","https://openalex.org/W2783487808","https://openalex.org/W2784146546","https://openalex.org/W2789665281","https://openalex.org/W2790018833","https://openalex.org/W2790264737","https://openalex.org/W2792640170","https://openalex.org/W2793660296","https://openalex.org/W2793692208","https://openalex.org/W2794353845","https://openalex.org/W2794930605","https://openalex.org/W2796970858","https://openalex.org/W2797421660","https://openalex.org/W2799885026","https://openalex.org/W2800823579","https://openalex.org/W2802744232","https://openalex.org/W2808592181","https://openalex.org/W2808835040","https://openalex.org/W2809927278","https://openalex.org/W2817396614","https://openalex.org/W2843813981","https://openalex.org/W2859470745","https://openalex.org/W2885285147","https://openalex.org/W2886387724","https://openalex.org/W2889646458","https://openalex.org/W2891631461","https://openalex.org/W2892102260","https://openalex.org/W2892364967","https://openalex.org/W2893518023","https://openalex.org/W2893971427","https://openalex.org/W2897062681","https://openalex.org/W2899434598","https://openalex.org/W2900121309","https://openalex.org/W2900187612","https://openalex.org/W2901470592","https://openalex.org/W2901577023","https://openalex.org/W2903403054","https://openalex.org/W2908423025","https://openalex.org/W2911615129","https://openalex.org/W2911768993","https://openalex.org/W2912725047","https://openalex.org/W2914065065","https://openalex.org/W2915985988","https://openalex.org/W2918755080","https://openalex.org/W2919429412","https://openalex.org/W2921819986","https://openalex.org/W2922787085","https://openalex.org/W2923030606","https://openalex.org/W2924570891","https://openalex.org/W2931278048","https://openalex.org/W2931478334","https://openalex.org/W2940255272","https://openalex.org/W2941505882","https://openalex.org/W2942802124","https://openalex.org/W2943263503","https://openalex.org/W2943460533","https://openalex.org/W2944248134","https://openalex.org/W2946076739","https://openalex.org/W2946743282","https://openalex.org/W2947806553","https://openalex.org/W2949191661","https://openalex.org/W2952975115","https://openalex.org/W2953602332","https://openalex.org/W2953806854","https://openalex.org/W2955297738","https://openalex.org/W2957271680","https://openalex.org/W2957572140","https://openalex.org/W2957922577","https://openalex.org/W2962784185","https://openalex.org/W2963446855","https://openalex.org/W2964172069","https://openalex.org/W2965938893","https://openalex.org/W2970774604","https://openalex.org/W2971345729","https://openalex.org/W2971435304","https://openalex.org/W2973587148","https://openalex.org/W2974353848","https://openalex.org/W2976314249","https://openalex.org/W2981656506","https://openalex.org/W2982349820","https://openalex.org/W2982651332","https://openalex.org/W2989100230","https://openalex.org/W2995199710","https://openalex.org/W2995351677","https://openalex.org/W2995463243","https://openalex.org/W2997622860","https://openalex.org/W2997650779","https://openalex.org/W2999020518","https://openalex.org/W3004060585","https://openalex.org/W3005135459","https://openalex.org/W3005196658","https://openalex.org/W3005551684","https://openalex.org/W3005857648","https://openalex.org/W3006645235","https://openalex.org/W3008106471","https://openalex.org/W3010489062","https://openalex.org/W3012290165","https://openalex.org/W3012365395","https://openalex.org/W3012747666","https://openalex.org/W3014195006","https://openalex.org/W3014420184","https://openalex.org/W3016963892","https://openalex.org/W3018568012","https://openalex.org/W3025069198","https://openalex.org/W3036773780","https://openalex.org/W3044886087","https://openalex.org/W4211116131","https://openalex.org/W4235299683"],"related_works":["https://openalex.org/W1998014006","https://openalex.org/W4392561554","https://openalex.org/W2884790554","https://openalex.org/W3211074477","https://openalex.org/W2124962668","https://openalex.org/W3189103601","https://openalex.org/W2795875828","https://openalex.org/W4387740591","https://openalex.org/W2362293903","https://openalex.org/W2635415917"],"abstract_inverted_index":{"Treatment":[0],"and":[1,25,45,78],"survival":[2],"of":[3,16,30,33,49,66],"cancer":[4,50],"has":[5],"improved":[6,28],"remarkably":[7],"over":[8],"the":[9,14],"last":[10],"decades.":[11],"In":[12],"particular":[13],"advent":[15],"targeted":[17,57],"therapies,":[18],"including":[19],"cell":[20],"cycle":[21],"inhibitors,":[22],"kinase":[23],"inhibitors":[24],"others,":[26],"have":[27],"outcomes":[29],"several":[31],"types":[32],"cancer.":[34],"However,":[35],"tumor":[36],"relapse":[37],"due":[38],"to":[39,54,70],"resistance":[40],"acquisition":[41],"is":[42,60],"often":[43],"observed":[44],"a":[46,90],"better":[47],"understanding":[48],"signaling":[51],"in":[52,75],"order":[53],"devise":[55],"novel":[56],"treatment":[58],"strategies":[59],"thus":[61],"still":[62],"required.":[63],"The":[64],"aim":[65],"this":[67],"thesis":[68],"was":[69],"further":[71],"investigate":[72],"phosphorylation":[73],"events":[74],"different":[76],"malignancies":[77],"determine":[79],"whether":[80],"low":[81],"molecular":[82],"weight":[83],"protein":[84],"tyrosine":[85],"phosphatase":[86],"could":[87],"potentially":[88],"be":[89],"target":[91],"for":[92],"treatment.":[93]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2025-10-10T00:00:00"}
