{"id":"https://openalex.org/W70112176","doi":null,"title":"MR proton spectroscopy in liver examinations of healthy individuals in vivo.","display_name":"MR proton spectroscopy in liver examinations of healthy individuals in vivo.","publication_year":2002,"publication_date":"2002-02-01","ids":{"openalex":"https://openalex.org/W70112176","mag":"70112176","pmid":"https://pubmed.ncbi.nlm.nih.gov/11859290"},"language":"en","primary_location":{"id":"pmid:11859290","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11859290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical science monitor : international medical journal of experimental and clinical research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112696270","display_name":"Eugeniusz Taras\u00f3w","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146122375","display_name":"Medical University of Bia\u0142ystok","ror":"https://ror.org/00y4ya841","country_code":"PL","type":"education","lineage":["https://openalex.org/I146122375"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Eugeniusz Taras\u00f3w","raw_affiliation_strings":["Department of Radiology, Medical University Hospital, ul. M. Curie-Sk\u0142odowskiej 24a, 15-642 Bia\u0142ystok, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Medical University Hospital, ul. M. Curie-Sk\u0142odowskiej 24a, 15-642 Bia\u0142ystok, Poland","institution_ids":["https://openalex.org/I146122375"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033503573","display_name":"Leszek Siergiejczyk","orcid":"https://orcid.org/0000-0003-0864-3281","observed_orcids":["https://orcid.org/0000-0003-0864-3281"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Leszek Siergiejczyk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077813829","display_name":"Anatol Panasiuk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anatol Panasiuk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107600986","display_name":"Bo\u017cena Kubas","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bozena Kubas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108545376","display_name":"Wojciech Dzienis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146122375","display_name":"Medical University of Bia\u0142ystok","ror":"https://ror.org/00y4ya841","country_code":"PL","type":"education","lineage":["https://openalex.org/I146122375"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Wojciech Dzienis","raw_affiliation_strings":["Department of Radiology, Medical University Hospital, ul. M. Curie-Sk\u0142odowskiej24a, 15-642 Bia\u0142ystok, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Medical University Hospital, ul. M. Curie-Sk\u0142odowskiej24a, 15-642 Bia\u0142ystok, Poland","institution_ids":["https://openalex.org/I146122375"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087014477","display_name":"Danuta Prokopowicz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Danuta Prokopowicz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5042318267","display_name":"Jerzy Micha\u0142 Walecki","orcid":"https://orcid.org/0000-0001-7494-7764","observed_orcids":["https://orcid.org/0000-0001-7494-7764"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jerzy Walecki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9576,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.84131162,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"8","issue":"2","first_page":"MT36","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9199000000953674,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9199000000953674,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.07680000364780426,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/1h-nmr-spectroscopy","display_name":"1H NMR","score":0.8209999799728394},{"id":"https://openalex.org/keywords/liver-metabolites","display_name":"liver metabolites","score":0.7929999828338623},{"id":"https://openalex.org/keywords/liver-lipid-content","display_name":"liver lipids","score":0.6140000224113464},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.8759999871253967},{"id":"https://openalex.org/keywords/glycogen","display_name":"glycogen","score":0.9210000038146973},{"id":"https://openalex.org/keywords/glutamine","display_name":"glutamine","score":0.7850000262260437},{"id":"https://openalex.org/keywords/glutamate","display_name":"glutamate","score":0.9629999995231628},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.8690000176429749},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8659999966621399},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7059999704360962},{"id":"https://openalex.org/keywords/healthy-volunteers","display_name":"healthy volunteers","score":0.6679999828338623}],"concepts":[{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.6237766742706299},{"id":"https://openalex.org/C2779349466","wikidata":"https://www.wikidata.org/wiki/Q181619","display_name":"Glutamine","level":3,"score":0.5900118947029114},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5708778500556946},{"id":"https://openalex.org/C103191249","wikidata":"https://www.wikidata.org/wiki/Q624073","display_name":"In vivo magnetic resonance spectroscopy","level":3,"score":0.5542932748794556},{"id":"https://openalex.org/C66974803","wikidata":"https://www.wikidata.org/wiki/Q10359898","display_name":"Nuclear magnetic resonance spectroscopy","level":2,"score":0.5385341048240662},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.5282064080238342},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5259547233581543},{"id":"https://openalex.org/C2777499176","wikidata":"https://www.wikidata.org/wiki/Q174936","display_name":"Glycogen","level":2,"score":0.5248054265975952},{"id":"https://openalex.org/C2988005100","wikidata":"https://www.wikidata.org/wiki/Q1979695","display_name":"Proton magnetic resonance","level":2,"score":0.5154500603675842},{"id":"https://openalex.org/C32891209","wikidata":"https://www.wikidata.org/wiki/Q483666","display_name":"Spectroscopy","level":2,"score":0.4625515341758728},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4625505805015564},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.46061086654663086},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4575878381729126},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.40191084146499634},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2773582935333252},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26718515157699585},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2669411599636078},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.25233909487724304},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.221366286277771},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.10912647843360901},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011522","descriptor_name":"Protons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:11859290","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11859290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical science monitor : international medical journal of experimental and clinical research","raw_type":"Journal Article"},{"id":"mag:70112176","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11859290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W75994028","https://openalex.org/W188433612","https://openalex.org/W1844698893","https://openalex.org/W1971364701","https://openalex.org/W1973282543","https://openalex.org/W1978335757","https://openalex.org/W1979992202","https://openalex.org/W1980099871","https://openalex.org/W2005781163","https://openalex.org/W2024314098","https://openalex.org/W2043066225","https://openalex.org/W2050385934","https://openalex.org/W2056731921","https://openalex.org/W2079508285","https://openalex.org/W2081405075","https://openalex.org/W2082552477","https://openalex.org/W2093071246","https://openalex.org/W2099270193","https://openalex.org/W2123365823","https://openalex.org/W2253667517","https://openalex.org/W2417696881","https://openalex.org/W2464218021","https://openalex.org/W2474585041","https://openalex.org/W4293174684"],"related_works":["https://openalex.org/W2379872032","https://openalex.org/W2351530290","https://openalex.org/W2118324180","https://openalex.org/W1986498969","https://openalex.org/W2383757176","https://openalex.org/W2352712877","https://openalex.org/W4226480013","https://openalex.org/W2083082495","https://openalex.org/W2029727035","https://openalex.org/W2347957388"],"abstract_inverted_index":{"BACKGROUND:":[0],"Magnetic":[1],"resonance":[2],"proton":[3],"spectroscopy":[4,33,64,200],"((1)H":[5],"MRS)":[6],"is":[7,25,227],"a":[8,85],"non-invasive":[9],"method":[10],"that":[11,222],"provides":[12],"in":[13,19,53,84,104,126,141,145,152,165,176,208,233],"vivo":[14],"measurement":[15],"of":[16,30,37,42,50,58,65,87,99,114,135,156,179,205],"metabolic":[17,56],"concentrations":[18],"body":[20,108,218],"tissue.":[21],"However,":[22],"relatively":[23],"little":[24],"known":[26],"about":[27],"the":[28,35,48,55,66,69,97,100,127,136,142,146,149,153,177,202,209,223,234],"potential":[29],"1H":[31],"MR":[32,105],"for":[34],"quantification":[36],"liver":[38,214],"metabolites.":[39],"The":[40,112,211],"aim":[41],"this":[43],"study":[44],"was":[45,82,187],"to":[46,225],"determine":[47],"usefulness":[49],"(1)H":[51],"MRS":[52],"establishing":[54],"pattern":[57],"normal":[59],"human":[60],"liver.":[61,210,235],"MATERIAL/METHODS:":[62],"Proton":[63,199],"liver,":[67],"using":[68],"Picker":[70],"system,":[71],"Edge":[72],"Eclipse":[73],"1.5T,":[74],"with":[75,230],"whole-body":[76],"coil":[77],"and":[78,107,121,133,160,184,196,217],"PRESS":[79],"35":[80],"sequence,":[81],"conducted":[83],"group":[86,178],"24":[88],"healthy":[89],"volunteers.":[90],"In":[91],"all":[92],"subjects":[93],"we":[94],"also":[95,228],"evaluated":[96],"thickness":[98],"subcutaneous":[101],"fat":[102],"tissue":[103],"images":[106],"mass":[109,219],"index.":[110],"RESULTS:":[111],"presence":[113],"lipid":[115,130,137,193,206,231],"resonances,":[116],"phosphoesters":[117],"(Pe),":[118],"glycogen/glucose":[119],"(Glc),":[120],"glutamine/glutamate":[122],"(Gln)":[123],"were":[124,139,163],"observed":[125,169],"spectra.":[128],"Total":[129],"concentration,":[131],"CH3":[132],"(CH2)n":[134],"resonances":[138],"higher":[140],"men":[143],"than":[144],"women,":[147],"while":[148],"metabolite":[150],"contents":[151,207,216],"CH2=CH-CH2":[154],"groups":[155],"lipids,":[157],"Pe,":[158],"Glc":[159],"Gln":[161],"peaks":[162],"similar":[164],"both":[166],"genders.":[167],"We":[168],"statistically":[170,189],"significant":[171,190],"positive":[172],"correlation,":[173],"more":[174],"apparent":[175],"men,":[180],"between":[181,192,213],"TL":[182],"concentration":[183,195],"BMI.":[185],"There":[186],"no":[188],"correlation":[191,212],"total":[194],"age.":[197],"CONCLUSIONS:":[198],"enables":[201],"quantitative":[203],"evaluation":[204],"triglyceride":[215],"index":[220],"shows":[221],"tendency":[224],"obesity":[226],"connected":[229],"accumulation":[232]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}