{"id":"https://openalex.org/W7009186017","doi":null,"title":"Association of depression and use of antidepressants with dementia and alzheimer\u2019s disease genetic risk","display_name":"Association of depression and use of antidepressants with dementia and alzheimer\u2019s disease genetic risk","publication_year":2021,"publication_date":"2021-01-01","ids":{"openalex":"https://openalex.org/W7009186017"},"language":"et","primary_location":{"id":"pmh:oai:dspace.ut.ee:10062/75777","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10062/75777","pdf_url":"https://dspace.ut.ee/bitstreams/26c2b468-c6e4-4d51-974c-58a9407b5377/download","source":{"id":"https://openalex.org/S4306401412","display_name":"DSpace repository (University of Tartu)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I56085075","host_organization_name":"University of Tartu","host_organization_lineage":["https://openalex.org/I56085075"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://dspace.ut.ee/bitstreams/26c2b468-c6e4-4d51-974c-58a9407b5377/download","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047763274","display_name":"Triinu Ojalo","orcid":"https://orcid.org/0000-0001-6587-9157","observed_orcids":["https://orcid.org/0000-0001-6587-9157"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ojalo, Triinu","raw_affiliation_strings":["Tartu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tartu","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5047763274"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.01679999940097332,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.004399999976158142,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.8790000081062317},{"id":"https://openalex.org/keywords/antidepressant-use","display_name":"antidepressant use","score":0.8730000257492065},{"id":"https://openalex.org/keywords/dementia-risk","display_name":"dementia risk","score":0.699999988079071},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.8659999966621399},{"id":"https://openalex.org/keywords/genetic-risk","display_name":"genetic risk","score":0.8949999809265137},{"id":"https://openalex.org/keywords/risk-factors-for-dementia","display_name":"dementia risk factors","score":0.550000011920929},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.515999972820282},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.8510000109672546},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.8610000014305115},{"id":"https://openalex.org/keywords/educational-attainment","display_name":"educational attainment","score":0.5920000076293945},{"id":"https://openalex.org/keywords/depression-prevention","display_name":"depression prevention","score":0.5339999794960022},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.48399999737739563},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.3449999988079071},{"id":"https://openalex.org/keywords/case-control-study","display_name":"case-control study","score":0.42899999022483826},{"id":"https://openalex.org/keywords/logistic-regression","display_name":"logistic regression","score":0.49799999594688416},{"id":"https://openalex.org/keywords/odds-ratio","display_name":"odds ratio","score":0.4690000116825104}],"concepts":[{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.3003999888896942},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2732999920845032},{"id":"https://openalex.org/C2780791683","wikidata":"https://www.wikidata.org/wiki/Q846785","display_name":"Action (physics)","level":2,"score":0.2621000111103058},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.24740000069141388},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.24140000343322754},{"id":"https://openalex.org/C18762648","wikidata":"https://www.wikidata.org/wiki/Q42213","display_name":"Work (physics)","level":2,"score":0.22930000722408295},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.19200000166893005},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.1891999989748001},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.16760000586509705},{"id":"https://openalex.org/C19417346","wikidata":"https://www.wikidata.org/wiki/Q7922","display_name":"Pedagogy","level":1,"score":0.1574999988079071}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:dspace.ut.ee:10062/75777","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10062/75777","pdf_url":"https://dspace.ut.ee/bitstreams/26c2b468-c6e4-4d51-974c-58a9407b5377/download","source":{"id":"https://openalex.org/S4306401412","display_name":"DSpace repository (University of Tartu)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I56085075","host_organization_name":"University of Tartu","host_organization_lineage":["https://openalex.org/I56085075"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"}],"best_oa_location":{"id":"pmh:oai:dspace.ut.ee:10062/75777","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10062/75777","pdf_url":"https://dspace.ut.ee/bitstreams/26c2b468-c6e4-4d51-974c-58a9407b5377/download","source":{"id":"https://openalex.org/S4306401412","display_name":"DSpace repository (University of Tartu)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I56085075","host_organization_name":"University of Tartu","host_organization_lineage":["https://openalex.org/I56085075"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7009186017.pdf","grobid_xml":"https://content.openalex.org/works/W7009186017.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W4780062","https://openalex.org/W1761919664","https://openalex.org/W1871783318","https://openalex.org/W1889987712","https://openalex.org/W1969756937","https://openalex.org/W2015172698","https://openalex.org/W2028466261","https://openalex.org/W2039400277","https://openalex.org/W2061180801","https://openalex.org/W2067722007","https://openalex.org/W2069447343","https://openalex.org/W2070102621","https://openalex.org/W2076143792","https://openalex.org/W2077912602","https://openalex.org/W2077975063","https://openalex.org/W2095755860","https://openalex.org/W2115034996","https://openalex.org/W2115444716","https://openalex.org/W2118826874","https://openalex.org/W2121298241","https://openalex.org/W2126418649","https://openalex.org/W2129497119","https://openalex.org/W2134585221","https://openalex.org/W2137944397","https://openalex.org/W2139214514","https://openalex.org/W2142827889","https://openalex.org/W2154569902","https://openalex.org/W2157633452","https://openalex.org/W2160309422","https://openalex.org/W2166336042","https://openalex.org/W2168516263","https://openalex.org/W2169795969","https://openalex.org/W2298359827","https://openalex.org/W2298887234","https://openalex.org/W2301371005","https://openalex.org/W2302818832","https://openalex.org/W2306793661","https://openalex.org/W2342525617","https://openalex.org/W2583703070","https://openalex.org/W2605242528","https://openalex.org/W2610475829","https://openalex.org/W2765790024","https://openalex.org/W2794676581","https://openalex.org/W2800521692","https://openalex.org/W2908002252","https://openalex.org/W2910843255","https://openalex.org/W2912770458","https://openalex.org/W2960583731","https://openalex.org/W2970844958","https://openalex.org/W2981624110","https://openalex.org/W2981862091","https://openalex.org/W2993096730","https://openalex.org/W3003326165","https://openalex.org/W3008981973","https://openalex.org/W3013444166","https://openalex.org/W3028329270","https://openalex.org/W3096936837","https://openalex.org/W3111789454","https://openalex.org/W4248184440"],"related_works":["https://openalex.org/W7126124365","https://openalex.org/W2561565201","https://openalex.org/W2912770458","https://openalex.org/W2092375570","https://openalex.org/W2610475829","https://openalex.org/W2605242528","https://openalex.org/W4282827905","https://openalex.org/W7007909190","https://openalex.org/W2618335481","https://openalex.org/W4387301669"],"abstract_inverted_index":{"Rahvastiku":[0],"vananemisega":[1],"on":[2,18,28,156],"maailmas":[3],"kasvanud":[4],"dementsuse":[5,40,71,85,107,114,136],"levimus.":[6],"Dementsuse":[7],"etioloogia":[8],"ei":[9],"ole":[10],"t\u00e4pselt":[11],"teada,":[12],"kuid":[13],"arvatakse,":[14],"et":[15,30,98,133,151],"selle":[16],"tekkes":[17],"kompleksselt":[19],"seotud":[20],"modifitseerimatud":[21],"bioloogilised":[22],"ja":[23,34,53,57,74,84,100,154],"modifitseeritavad":[24],"elustiilifaktorid.":[25],"Varasemates":[26],"uuringutes":[27,128],"leitud,":[29],"hilisema":[31],"ea":[32],"depressioon":[33,52,99,134],"antikolinergiliste":[35],"antidepressantide":[36,54,101],"tarvitamine":[37,104],"t\u00f5stavad":[38],"oluliselt":[39],"riski.":[41],"K\u00e4esoleva":[42],"uuringu":[43],"eesm\u00e4rgiks":[44],"oli":[45],"uurida":[46],"Eesti":[47],"Geenivaramu":[48],"valimil,":[49],"kuidas":[50],"ennustavad":[51],"kasutus":[55],"dementsust":[56],"kas":[58],"depressiooni":[59,146,152],"diagnoos":[60],"muudab":[61],"Alzheimeri":[62,139],"t\u00f5ve":[63,140],"geneetilise":[64,141,158],"riskiskoori":[65],"seost":[66],"dementsusega.":[67],"Juht-kontrolluuringus":[68],"sobitati":[69],"1026-le":[70],"juhule":[72],"soo":[73],"vanuse":[75],"j\u00e4rgi":[76],"randomiseeritult":[77],"kolm":[78],"kontrollisikut":[79],"(koguvalim":[80],"n":[81],"=":[82],"4104)":[83],"suhtelise":[86],"t\u00f5en\u00e4osuse":[87],"leidmiseks":[88],"seoses":[89],"riskifaktoritega":[90],"viidi":[91],"l\u00e4bi":[92],"logistilised":[93],"regressioonid.":[94],"Uuringu":[95],"tulemustes":[96],"leiti,":[97,132],"(k.a":[102],"antikolinergiliste)":[103],"t\u00f5stsid":[105],"m\u00e4rkimisv\u00e4\u00e4rselt":[106],"suhtelist":[108,137],"t\u00f5en\u00e4osust,":[109],"sealjuures":[110],"kontrollides":[111],"teiste":[112],"teadaolevate":[113],"riskitegurite":[115],"suhtes":[116],"(suitsetamise":[117],"staatus,":[118],"haridustase,":[119],"KMI,":[120],"kardiovaskulaarsed":[121],"haigused),":[122],"mis":[123,148],"pakub":[124],"t\u00e4iendavat":[125],"t\u00f5endust":[126],"varasemates":[127],"leitud":[129],"tulemustele.":[130],"Lisaks":[131],"t\u00f5stis":[135],"t\u00f5en\u00e4osust":[138],"riskifaktori":[142],"k\u00f5igis":[143],"kvartiilides":[144],"v\u00f5rreldes":[145],"puudumisega,":[147],"viitab":[149],"v\u00f5imalusele,":[150],"ennetuse":[153],"ravimisega":[155],"v\u00f5imalik":[157],"riski":[159],"m\u00f5ju":[160],"v\u00e4hendada.":[161]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2025-10-10T00:00:00"}