{"id":"https://openalex.org/W6987854993","doi":null,"title":"Type 1 diabetes in adults: modern treatment and risk of major coronary events","display_name":"Type 1 diabetes in adults: modern treatment and risk of major coronary events","publication_year":2018,"publication_date":"2018-01-22","ids":{"openalex":"https://openalex.org/W6987854993"},"language":"en","primary_location":{"id":"pmh:oai:gupea.ub.gu.se:2077/54198","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2077/54198","pdf_url":"http://hdl.handle.net/2077/54198","source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2077/54198","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037760732","display_name":"Viktorija Matuleviciene","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Matuleviciene An\u00e4ngen, Viktorija","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5037760732"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10793","display_name":"Diabetes Management and Education","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9509999752044678},{"id":"https://openalex.org/keywords/adults","display_name":"adults","score":0.4869999885559082},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.9089999794960022},{"id":"https://openalex.org/keywords/hba1c-monitoring","display_name":"HbA1c monitoring","score":0.847000002861023},{"id":"https://openalex.org/keywords/continuous-glucose-monitoring","display_name":"continuous glucose monitoring","score":0.5799999833106995},{"id":"https://openalex.org/keywords/cgm-accuracy","display_name":"CGM accuracy","score":0.7739999890327454},{"id":"https://openalex.org/keywords/continuous-subcutaneous-insulin-infusion","display_name":"insulin pump therapy","score":0.7639999985694885},{"id":"https://openalex.org/keywords/insulin-injection","display_name":"insulin injection","score":0.6069999933242798},{"id":"https://openalex.org/keywords/treatment-satisfaction","display_name":"treatment satisfaction","score":0.7099999785423279},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.6370000243186951},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.9399999976158142},{"id":"https://openalex.org/keywords/coronary-events","display_name":"coronary events","score":0.8080000281333923},{"id":"https://openalex.org/keywords/renal-complications","display_name":"renal complications","score":0.6869999766349792},{"id":"https://openalex.org/keywords/diabetes-care-guidelines","display_name":"diabetes management guidelines","score":0.5519999861717224},{"id":"https://openalex.org/keywords/national-diabetes-register","display_name":"National Diabetes Register","score":0.699999988079071},{"id":"https://openalex.org/keywords/sweden","display_name":"Sweden","score":0.5490000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9133999943733215},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.8379999995231628},{"id":"https://openalex.org/C2779794567","wikidata":"https://www.wikidata.org/wiki/Q941674","display_name":"Insulin pump","level":4,"score":0.7142999768257141},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6812000274658203},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.4726000130176544},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42179998755455017},{"id":"https://openalex.org/C2986379492","wikidata":"https://www.wikidata.org/wiki/Q1638492","display_name":"Continuous glucose monitoring","level":4,"score":0.392300009727478},{"id":"https://openalex.org/C3018376624","wikidata":"https://www.wikidata.org/wiki/Q1100933","display_name":"Diabetes treatment","level":4,"score":0.3880000114440918},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.38589999079704285},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3580999970436096},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3513999879360199},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.3384999930858612},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.3068999946117401},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.3001999855041504},{"id":"https://openalex.org/C2779318504","wikidata":"https://www.wikidata.org/wiki/Q1438035","display_name":"Research design","level":2,"score":0.2985999882221222},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.2957000136375427},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.2921000123023987},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.29030001163482666},{"id":"https://openalex.org/C2779524580","wikidata":"https://www.wikidata.org/wiki/Q4927806","display_name":"Blood glucose monitoring","level":3,"score":0.28049999475479126},{"id":"https://openalex.org/C3020737875","wikidata":"https://www.wikidata.org/wiki/Q1100933","display_name":"Diabetes control","level":4,"score":0.2761000096797943},{"id":"https://openalex.org/C2994527087","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin delivery","level":4,"score":0.2703000009059906},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.2685000002384186},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.2599000036716461},{"id":"https://openalex.org/C2908918659","wikidata":"https://www.wikidata.org/wiki/Q4927806","display_name":"Blood Glucose Self-Monitoring","level":5,"score":0.25459998846054077},{"id":"https://openalex.org/C2777698277","wikidata":"https://www.wikidata.org/wiki/Q266018","display_name":"Acute coronary syndrome","level":3,"score":0.25130000710487366}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:gupea.ub.gu.se:2077/54198","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2077/54198","pdf_url":"http://hdl.handle.net/2077/54198","source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"}],"best_oa_location":{"id":"pmh:oai:gupea.ub.gu.se:2077/54198","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2077/54198","pdf_url":"http://hdl.handle.net/2077/54198","source":{"id":"https://openalex.org/S4306401168","display_name":"Gothenburg University Publications Electronic Archive (Gothenburg University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I881427289","host_organization_name":"University of Gothenburg","host_organization_lineage":["https://openalex.org/I881427289"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Doctoral thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W6987854993.pdf","grobid_xml":"https://content.openalex.org/works/W6987854993.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3142858018","https://openalex.org/W4381377170","https://openalex.org/W4316097022","https://openalex.org/W4292615696","https://openalex.org/W2946421787","https://openalex.org/W4399688190","https://openalex.org/W3042558568","https://openalex.org/W4377221471","https://openalex.org/W4400820628","https://openalex.org/W2948204413"],"abstract_inverted_index":{"Background:":[0],"According":[1],"to":[2,61,146,169,301,400],"the":[3,70,93,134,181,199,223,228,330,414,466,516],"National":[4,331],"Diabetes":[5],"Register":[6],"(NDR)":[7],"report":[8],"(2016),":[9],"21.2%":[10],"of":[11,30,92,137,227,291,293,333,346,417,468,490,508,518],"adults":[12],"with":[13,22,83,143,165,207,232,253,264,298,327,351,372,435,460,484],"type":[14],"1":[15],"diabetes":[16,64,191,474],"(T1D)":[17],"achieve":[18],"glycaemic":[19,35,170,486],"targets":[20],"measured":[21],"HbA1c":[23,50,84,182,220,357,377,433,455],"(52":[24],"mmol":[25,39,427,438],"/":[26,40,428,439],"mol)":[27],"and":[28,108,172,177,209,225,230,250,259,280,315,344,348,379,394,488,505],"20.1%":[29],"patients":[31,188,231,263,271,307],"have":[32,121,155],"very":[33,431],"poor":[34],"control":[36,171,487],"(HbA1c>":[37],"70":[38],"mol).":[41],"In":[42,242,288],"recent":[43],"years,":[44],"a":[45,58,283,289,391,448,451],"positive":[46],"trend":[47],"in":[48,86,103,150,167,193,239,282,296,309,363,454,475,521],"improving":[49,499],"has":[51,447],"been":[52,156],"observed;":[53],"despite":[54],"it,":[55],"there":[56],"is":[57,100,112,133,398,479],"great":[59],"need":[60,380],"understand":[62],"how":[63],"care":[65],"can":[66],"be":[67],"improved.":[68],"Thus,":[69],"following":[71],"questions":[72],"were":[73,196,235,266,337],"formulated:":[74],"To":[75,179],"what":[76],"extent":[77],"are":[78,512],"international":[79],"guidelines":[80,154],"for":[81,141,163,213,277,413,482,498,514],"visits":[82,276],"controls":[85,302,320,358,368,378],"T1D":[87,144,149,166,208,265,299,461],"followed?":[88],"(Study":[89,115,130,175],"I)":[90],"Which":[91],"two":[94],"most":[95,101,113],"commonly":[96],"used":[97],"CGM":[98,110,256],"sensors":[99],"accurate":[102],"estimating":[104],"blood":[105,278],"glucose":[106],"levels":[107],"which":[109,397],"system":[111,203],"user-friendly?":[114],"II)":[116],"Can":[117],"some":[118],"patient":[119],"subgroups":[120],"greater":[122,415],"effect":[123,416],"on":[124,248,339,361,404,420,441,495],"insulin":[125,210,233,373,418,444],"pump":[126,211,419,445],"treatment":[127,251,286,395,405,446],"than":[128,355,471],"others?":[129],"III)":[131],"What":[132],"excess":[135],"risk":[136,161,292,467,478,517],"acute":[138],"coronary":[139,509,519],"events":[140],"persons":[142,147,297,472],"compared":[145,300,434],"without":[148,473],"Sweden,":[151],"when":[152],"modern":[153],"implemented?":[157],"How":[158],"does":[159],"this":[160],"differ":[162],"people":[164,483],"relation":[168],"renal":[173,491],"complications?":[174],"IV)\\nMaterial":[176],"methods:":[178],"calculate":[180],"yearly":[183],"measurement":[184,221],"rate,":[185],"we":[186,305],"included":[187,236,267,306],"from":[189,237,329],"10":[190],"clinics":[192],"Sweden.":[194,476],"Data":[195],"collected":[197,338],"via":[198],"Diab-Base":[200],"electronic":[201],"record":[202],"(study":[204,268,303,383,406,457],"I).":[205,384],"Persons":[206,350,459],"use":[212],"at":[214,222,273,430],"least":[215],"5":[216,316],"years":[217],"who":[218],"had":[219,390,462],"beginning":[224],"end":[226],"period":[229],"injections":[234,374],"Dia-Base":[238],"study":[240,290],"III.":[241],"an":[243],"economically":[244],"independent":[245],"clinical":[246],"trial":[247],"precision":[249,393],"satisfaction":[252],"2":[254,356,437],"different":[255],"(Dexcom":[257],"G4":[258,389],"Enlite)":[260],"systems,":[261],"ambulatory":[262],"II).":[269,407],"All":[270],"arrived":[272],"three":[274],"scheduled":[275],"sampling":[279],"filled":[281],"questionnaire":[284],"regarding":[285],"satisfaction.":[287],"myocardial":[294],"infarction":[295,470],"IV),":[304],"registered":[308],"NDR":[310],"(n":[311,321],"=":[312,322],"33":[313],"886)":[314],"randomly":[317],"selected":[318],"matched":[319],"169":[323],"223).":[324],"Through":[325],"interaction":[326],"data":[328,336],"Board":[332],"Social":[334],"Services,":[335],"cardiovascular":[340],"disease,":[341],"death":[342],"date":[343],"causes":[345],"death.\\nResults":[347],"conclusions:":[349],"T1D,":[352],"get":[353],"fewer":[354,376],"per":[359,369],"year":[360],"average":[362],"Sweden":[364],"against":[365],"recommended":[366],"4":[367,464],"year.":[370],"Patients":[371],"receive":[375],"extra":[381],"focus":[382,494],"We":[385,408],"found":[386,409],"that":[387],"DexCom":[388],"higher":[392],"satisfaction,":[396],"likely":[399],"make":[401],"adequate":[402],"decisions":[403],"no":[410],"strong":[411],"predictors":[412],"lowering":[421],"HbA1c.":[422],"The":[423,477],"decrease":[424,453],"was":[425],"2.5":[426],"mol":[429,440],"high":[432],"about":[436,463],"average.":[442],"However,":[443],"value":[449],"since":[450],"certain":[452],"occurs":[456],"III).":[458],"times":[465],"cardiac":[469],"significantly":[480],"lower":[481],"good":[485],"absence":[489],"complications.":[492],"Continued":[493],"better":[496],"methods":[497],"HbA1c,":[500],"as":[501,503],"well":[502],"primary":[504],"secondary":[506],"prevention":[507],"artery":[510],"disease":[511],"essential":[513],"reducing":[515],"complications":[520],"T1D.":[522]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2025-10-10T00:00:00"}