{"id":"https://openalex.org/W6983177375","doi":null,"title":"Long-Term Outcome of Childhood Asthma: Characterizing COPD-A and COPD-C Subtypes in Adulthood","display_name":"Long-Term Outcome of Childhood Asthma: Characterizing COPD-A and COPD-C Subtypes in Adulthood","publication_year":2024,"publication_date":"2024-12-01","ids":{"openalex":"https://openalex.org/W6983177375"},"language":"en","primary_location":{"id":"pmh:oai:doaj.org/article:a115226183614917ac7261093592b207","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a115226183614917ac7261093592b207","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Asthma and Allergy, Vol Volume 17, Pp 1291-1300 (2024)","raw_type":"article"},"volume":null,"type":"article","indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/a115226183614917ac7261093592b207","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044697227","display_name":"Osman Savran","orcid":"https://orcid.org/0000-0002-2115-6536","observed_orcids":["https://orcid.org/0000-0002-2115-6536"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Savran O","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"B\u00f8nnelykke K","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B\u00f8nnelykke K","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5145184275","display_name":"Ulrik CS","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ulrik CS","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.44738698,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.7954000234603882,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.7954000234603882,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.20149999856948853,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/childhood-asthma","display_name":"childhood asthma","score":0.9520000219345093},{"id":"https://openalex.org/keywords/gold-classification","display_name":"GOLD classification","score":0.6439999938011169},{"id":"https://openalex.org/keywords/copd-subtypes","display_name":"COPD subtypes","score":0.7039999961853027},{"id":"https://openalex.org/keywords/long-term-outcomes","display_name":"long-term outcomes","score":0.5989999771118164},{"id":"https://openalex.org/keywords/airflow-obstruction","display_name":"airflow obstruction","score":0.5910000205039978},{"id":"https://openalex.org/keywords/tobacco-smoke-exposure","display_name":"tobacco smoke exposure","score":0.4860000014305115},{"id":"https://openalex.org/keywords/asthma-exacerbations","display_name":"asthma exacerbations","score":0.5889999866485596},{"id":"https://openalex.org/keywords/oral-corticosteroids","display_name":"oral corticosteroids","score":0.8050000071525574},{"id":"https://openalex.org/keywords/dyspnea","display_name":"dyspnea","score":0.7829999923706055},{"id":"https://openalex.org/keywords/blood-eosinophils","display_name":"blood eosinophils","score":0.9179999828338623},{"id":"https://openalex.org/keywords/exhaled-nitric-oxide","display_name":"exhaled nitric oxide","score":0.9419999718666077},{"id":"https://openalex.org/keywords/copd-risk-factors","display_name":"COPD risk factors","score":0.4650000035762787},{"id":"https://openalex.org/keywords/copd-progression","display_name":"COPD progression","score":0.3479999899864197}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8550999760627747},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.7870000004768372},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6209999918937683},{"id":"https://openalex.org/C2777014857","wikidata":"https://www.wikidata.org/wiki/Q1383410","display_name":"Exacerbation","level":2,"score":0.6026999950408936},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5881999731063843},{"id":"https://openalex.org/C2776780178","wikidata":"https://www.wikidata.org/wiki/Q199804","display_name":"COPD","level":2,"score":0.5720000267028809},{"id":"https://openalex.org/C164622146","wikidata":"https://www.wikidata.org/wiki/Q9035","display_name":"Danish","level":2,"score":0.5591999888420105},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.5491999983787537},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.48899999260902405},{"id":"https://openalex.org/C206179267","wikidata":"https://www.wikidata.org/wiki/Q188952","display_name":"Medical history","level":2,"score":0.3930000066757202},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.3709999918937683},{"id":"https://openalex.org/C195910791","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Medical record","level":2,"score":0.35120001435279846},{"id":"https://openalex.org/C2909082789","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma exacerbations","level":3,"score":0.3395000100135803},{"id":"https://openalex.org/C3017595490","wikidata":"https://www.wikidata.org/wiki/Q17006263","display_name":"University hospital","level":2,"score":0.33660000562667847},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.3149000108242035},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.31220000982284546},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.31060001254081726},{"id":"https://openalex.org/C2780505380","wikidata":"https://www.wikidata.org/wiki/Q7142931","display_name":"Past medical history","level":2,"score":0.3012000024318695},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.2939999997615814},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.29190000891685486},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.26429998874664307},{"id":"https://openalex.org/C986699","wikidata":"https://www.wikidata.org/wiki/Q7939","display_name":"El Ni\u00f1o","level":2,"score":0.26030001044273376},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.25920000672340393},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.25769999623298645},{"id":"https://openalex.org/C163276114","wikidata":"https://www.wikidata.org/wiki/Q484591","display_name":"Natural history","level":2,"score":0.2547000050544739},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.2538999915122986},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.25130000710487366}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:doaj.org/article:a115226183614917ac7261093592b207","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a115226183614917ac7261093592b207","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Asthma and Allergy, Vol Volume 17, Pp 1291-1300 (2024)","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:a115226183614917ac7261093592b207","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/a115226183614917ac7261093592b207","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Asthma and Allergy, Vol Volume 17, Pp 1291-1300 (2024)","raw_type":"article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.7914541363716125,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Osman":[0,45],"Savran,1":[1],"Klaus":[2],"B\u00f8nnelykke,2,3":[3],"Charlotte":[4],"Suppli":[5],"Ulrik1,2":[6],"1Respiratory":[7],"Research":[8,48,254],"Unit":[9,49],"Hvidovre,":[10,19,20,50,59,60],"Department":[11,51],"of":[12,23,27,52,76,111,116,125,131,191,195,231,314,337,348,353],"Respiratory":[13,47,53],"Medicine,":[14,25],"Copenhagen":[15,32,39,55],"University":[16,26,40,56],"Hospital":[17,41,57],"-":[18,58],"Denmark;":[21,30],"2Institute":[22],"Clinical":[24],"Copenhagen,":[28,29],"3COPSAC,":[31],"Prospective":[33],"Studies":[34],"on":[35],"Asthma":[36,66],"in":[37,67,102,108,147,153,234,345],"Childhood,":[38],"Gentofte,":[42,43],"DenmarkCorrespondence:":[44],"Savran,":[46],"Medicine":[54],"Denmark,":[61],"Email":[62],"osmansavran@ymail.comBackground":[63],"and":[64,78,104,120,135,160,168,173,199,207,219,243,260,292,307,319,334,343],"Aim:":[65],"early":[68,357],"life":[69],"has":[70],"been":[71],"linked":[72],"to":[73,80,92,210,275,304],"subsequent":[74],"development":[75],"COPD":[77,83,340],"according":[79],"GOLD":[81,98],"2023":[82],"may":[84],"be":[85],"divided":[86,151],"into":[87,158],"distinct":[88],"subtypes.":[89],"We":[90],"aimed":[91],"investigate":[93],"factors":[94],"associated":[95],"with":[96,113,128,188,212,217,270,302,316,350],"the":[97,143,235,276,279,312,338],"classification":[99],"COPD-A":[100,159,206,218,280,303,342],"(asthma":[101],"childhood)":[103],"COPD-C":[105,220,247,277,306,344],"(tobacco":[106],"exposure)":[107],"a":[109,114,123,129,136,154,189,250,331,346,351],"cohort":[110,124,184,347,363],"adults":[112,127,187,349],"history":[115,130,190,352],"severe":[117,132,192,354],"childhood":[118,133,141,193,355],"asthma.Patients":[119],"Methods:":[121],"In":[122],"Danish":[126],"asthma":[134,144],"previous":[137],"4-month":[138],"stay":[139],"during":[140],"at":[142,225],"care":[145],"facility":[146],"Kongsberg,":[148],"Norway,":[149],"we":[150],"participants":[152,301,308,315],"long-term":[155],"follow-up":[156],"examination":[157],"COPD-C,":[161],"defined":[162],"as":[163,205,326],"post-bronchodilator":[164],"FEV1/FVC":[165],"<":[166],"0.7,":[167],"never-smoker":[169],"or":[170],"ever-smoker,":[171],"respectively,":[172,202],"no":[174,213,271],"airflow":[175,214,272,310],"limitation.":[176,273],"Characteristics":[177],"between":[178],"groups":[179],"were":[180,203],"analysed.Results:":[181],"The":[182,246],"study":[183,329],"comprised":[185],"232":[186],"asthma,":[194,359],"whom":[196],"30":[197],"(13%)":[198],"23":[200],"(10%),":[201],"classified":[204],"COPD-C.":[208],"Compared":[209,274],"those":[211,269],"limitation,":[215,311],"individuals":[216],"more":[221,323],"often":[222],"had":[223,224,249,282],"least":[226],"one":[227],"exacerbation":[228],"(filled":[229],"prescription":[230],"oral":[232],"corticosteroid)":[233],"past":[236],"12":[237],"months":[238],"(risk":[239],"ratio":[240],"[RR]":[241],"1.83":[242],"2.65,":[244],"respectively).":[245],"group":[248,281],"significantly":[251,261],"higher":[252,262,283],"Medical":[253],"Council":[255],"dyspnoea":[256],"score":[257],"(p<":[258,266],"0.01)":[259,267],"blood":[263],"eosinophil":[264],"count":[265],"than":[268,324],"group,":[278],"fractional":[284],"exhaled":[285],"nitric":[286],"oxide":[287],"(mean":[288,294],"29":[289],"[SD":[290,296],"28])":[291],"FEV1%pred":[293],"75":[295],"20]).":[297],"Finally,":[298],"when":[299],"comparing":[300],"both":[305],"without":[309],"proportion":[313],"osteoporosis":[317],"(17%)":[318],"depression":[320],"(10%)":[321],"was":[322],"twice":[325],"high.Conclusion:":[327],"Our":[328],"revealed":[330],"high":[332],"prevalence":[333],"unique":[335],"features":[336],"two":[339],"subtypes":[341],"asthma.Keywords:":[356],"life,":[358],"etiotypes,":[360],"adult,":[361],"Kongsberg":[362]},"counts_by_year":[],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}