{"id":"https://openalex.org/W6969033069","doi":"https://doi.org/10.5281/zenodo.8424867","title":"Symmetry-Adapted Markov State Models of Closing, Opening, and Desensitizing in ALPHA-7 nicotinic acetylcholine receptors","display_name":"Symmetry-Adapted Markov State Models of Closing, Opening, and Desensitizing in ALPHA-7 nicotinic acetylcholine receptors","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W6969033069","doi":"https://doi.org/10.5281/zenodo.8424867"},"language":"en","primary_location":{"id":"doi:10.5281/zenodo.11117001","doi":"https://doi.org/10.5281/zenodo.11117001","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.11117001","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"volume":null,"type":"article","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.5281/zenodo.11117001","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5126426809","display_name":"Yuxuan Zhuang","orcid":"https://orcid.org/0000-0003-4390-8556","observed_orcids":["https://orcid.org/0000-0003-4390-8556"]},"institutions":[{"id":"https://openalex.org/I161593684","display_name":"Stockholm University","ror":"https://ror.org/05f0yaq80","country_code":"SE","type":"education","lineage":["https://openalex.org/I161593684"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Zhuang, Yuxuan","raw_affiliation_strings":["Stockholm University"],"raw_orcid":"https://orcid.org/0000-0003-4390-8556","affiliations":[{"raw_affiliation_string":"Stockholm University","institution_ids":["https://openalex.org/I161593684"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009401803","display_name":"Rebecca J. Howard","orcid":"https://orcid.org/0000-0003-2049-3378","observed_orcids":["https://orcid.org/0000-0003-2049-3378"]},"institutions":[{"id":"https://openalex.org/I161593684","display_name":"Stockholm University","ror":"https://ror.org/05f0yaq80","country_code":"SE","type":"education","lineage":["https://openalex.org/I161593684"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Howard, Rebecca","raw_affiliation_strings":["Stockholm University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stockholm University","institution_ids":["https://openalex.org/I161593684"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008875190","display_name":"Erik R. Lindahl","orcid":"https://orcid.org/0000-0002-2734-2794","observed_orcids":["https://orcid.org/0000-0002-2734-2794","https://orcid.org/0000-0003-1333-5398"]},"institutions":[{"id":"https://openalex.org/I161593684","display_name":"Stockholm University","ror":"https://ror.org/05f0yaq80","country_code":"SE","type":"education","lineage":["https://openalex.org/I161593684"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Lindahl, Erik","raw_affiliation_strings":["Stockholm University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Stockholm University","institution_ids":["https://openalex.org/I161593684"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I161593684"],"apc_list":null,"apc_paid":null,"fwci":0.0889,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.35193419,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.9609000086784363,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.016499999910593033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.006800000090152025,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha7-nicotinic-acetylcholine-receptor","display_name":"alpha7 nicotinic acetylcholine receptor","score":0.9269999861717224},{"id":"https://openalex.org/keywords/markov-state-models","display_name":"Markov state models","score":0.7689999938011169},{"id":"https://openalex.org/keywords/receptor-desensitization","display_name":"receptor desensitization","score":0.7739999890327454},{"id":"https://openalex.org/keywords/receptor-gating","display_name":"receptor gating","score":0.5270000100135803},{"id":"https://openalex.org/keywords/molecular-dynamics-trajectories","display_name":"molecular dynamics trajectories","score":0.6679999828338623}],"concepts":[{"id":"https://openalex.org/C188987157","wikidata":"https://www.wikidata.org/wiki/Q7030581","display_name":"Nicotinic agonist","level":3,"score":0.7337999939918518},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6804999709129333},{"id":"https://openalex.org/C80161118","wikidata":"https://www.wikidata.org/wiki/Q408520","display_name":"Acetylcholine receptor","level":3,"score":0.529699981212616},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5170000195503235},{"id":"https://openalex.org/C45855136","wikidata":"https://www.wikidata.org/wiki/Q4734890","display_name":"Ganglion type nicotinic receptor","level":5,"score":0.48510000109672546},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4072999954223633},{"id":"https://openalex.org/C2779570518","wikidata":"https://www.wikidata.org/wiki/Q412256","display_name":"Nicotinic acetylcholine receptor","level":4,"score":0.3903999924659729},{"id":"https://openalex.org/C51927110","wikidata":"https://www.wikidata.org/wiki/Q4734895","display_name":"Alpha-4 beta-2 nicotinic receptor","level":5,"score":0.3781000077724457},{"id":"https://openalex.org/C48103436","wikidata":"https://www.wikidata.org/wiki/Q599031","display_name":"State (computer science)","level":2,"score":0.36570000648498535},{"id":"https://openalex.org/C2775910092","wikidata":"https://www.wikidata.org/wiki/Q180623","display_name":"Acetylcholine","level":2,"score":0.3431999981403351},{"id":"https://openalex.org/C98763669","wikidata":"https://www.wikidata.org/wiki/Q176645","display_name":"Markov chain","level":2,"score":0.33489999175071716},{"id":"https://openalex.org/C2984679396","wikidata":"https://www.wikidata.org/wiki/Q7602986","display_name":"State dependent","level":2,"score":0.27889999747276306},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2678000032901764},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2615000009536743},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.26019999384880066}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.5281/zenodo.11117001","doi":"https://doi.org/10.5281/zenodo.11117001","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.11117001","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.5281/zenodo.8424867","doi":"https://doi.org/10.5281/zenodo.8424867","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.8424867","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.5281/zenodo.8424868","doi":"https://doi.org/10.5281/zenodo.8424868","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.8424868","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.5281/zenodo.11117001","doi":"https://doi.org/10.5281/zenodo.11117001","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.11117001","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6950121834","https://openalex.org/W6893086163","https://openalex.org/W4403532836","https://openalex.org/W7152050091","https://openalex.org/W7039678695","https://openalex.org/W4393176925","https://openalex.org/W7120869015","https://openalex.org/W7024746235","https://openalex.org/W7096769592","https://openalex.org/W6891262459"],"abstract_inverted_index":{"Trajectories,":[0],"analysis":[1,5],"files":[2],"for":[3],"MSM":[4],"of":[6],"a7":[7],"nicotinic":[8],"receptor":[9],"(APO":[10],"and":[11],"CHOL":[12],"systems)":[13]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}