{"id":"https://openalex.org/W69551350","doi":null,"title":"Investigations into the influence of Parathyroid hormone on gene expression in the Colorectal Epithelium","display_name":"Investigations into the influence of Parathyroid hormone on gene expression in the Colorectal Epithelium","publication_year":2012,"publication_date":"2012-06-01","ids":{"openalex":"https://openalex.org/W69551350","mag":"69551350"},"language":"en","primary_location":{"id":"pmh:oai:etheses.bham.ac.uk:3529","doi":null,"is_oa":false,"landing_page_url":"http://etheses.bham.ac.uk/3529/2/Walker_12_PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/3529/2/Walker_12_PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://etheses.bham.ac.uk/3529/2/Walker_12_PhD.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022584491","display_name":"Michael Andrew Walker","orcid":"https://orcid.org/0000-0001-5422-821X","observed_orcids":["https://orcid.org/0000-0001-5422-821X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Michael Walker","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5022584491"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.6060000061988831,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.6060000061988831,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.133200004696846,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.11980000138282776,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":1.0},{"id":"https://openalex.org/keywords/colorectal-epithelium","display_name":"colorectal epithelium","score":0.925000011920929},{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.7260000109672546},{"id":"https://openalex.org/keywords/dietary-calcium","display_name":"dietary calcium","score":0.9200000166893005},{"id":"https://openalex.org/keywords/calcium-supplementation","display_name":"calcium supplementation","score":0.8199999928474426},{"id":"https://openalex.org/keywords/parathyroid-hormone-receptor-1","display_name":"parathyroid hormone type 1 receptor","score":0.9010000228881836},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.7609999775886536},{"id":"https://openalex.org/keywords/wnt-signalling-pathway","display_name":"Wnt signalling pathway","score":0.8840000033378601},{"id":"https://openalex.org/keywords/cell-differentiation","display_name":"cell differentiation","score":0.6460000276565552},{"id":"https://openalex.org/keywords/rectal-mucosa","display_name":"rectal mucosa","score":0.9350000023841858},{"id":"https://openalex.org/keywords/serum-pth","display_name":"serum PTH","score":0.5479999780654907}],"concepts":[{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.7636917233467102},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7147818207740784},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7056549191474915},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.6752331852912903},{"id":"https://openalex.org/C142590548","wikidata":"https://www.wikidata.org/wiki/Q417801","display_name":"Calcium-sensing receptor","level":4,"score":0.586677074432373},{"id":"https://openalex.org/C137620995","wikidata":"https://www.wikidata.org/wiki/Q155769","display_name":"Wnt signaling pathway","level":3,"score":0.5782146453857422},{"id":"https://openalex.org/C87975464","wikidata":"https://www.wikidata.org/wiki/Q910704","display_name":"Calcium metabolism","level":3,"score":0.5502413511276245},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5225455164909363},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.48250412940979004},{"id":"https://openalex.org/C179639408","wikidata":"https://www.wikidata.org/wiki/Q417057","display_name":"Calcitriol receptor","level":3,"score":0.475635290145874},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46967893838882446},{"id":"https://openalex.org/C529295009","wikidata":"https://www.wikidata.org/wiki/Q41301","display_name":"Epithelium","level":2,"score":0.4449618458747864},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.4367208182811737},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.3103576898574829},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2996717095375061},{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.26286327838897705},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22565898299217224},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.1974201202392578},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1149960458278656},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08057296276092529}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:etheses.bham.ac.uk:3529","doi":null,"is_oa":false,"landing_page_url":"http://etheses.bham.ac.uk/3529/2/Walker_12_PhD.pdf","pdf_url":"http://etheses.bham.ac.uk/3529/2/Walker_12_PhD.pdf","source":{"id":"https://openalex.org/S4306402357","display_name":"University of Birmingham Institutional Research Archive (University of Birmingham)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79619799","host_organization_name":"University of Birmingham","host_organization_lineage":["https://openalex.org/I79619799"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"pmh:oai:uilis.unsyiah.ac.id:50399","doi":null,"is_oa":true,"landing_page_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/50399","pdf_url":"http://etheses.bham.ac.uk/3529/2/Walker_12_PhD.pdf","source":{"id":"https://openalex.org/S4377196378","display_name":"UPT. Syiah Kuala University Library (Syiah Kuala University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187494767","host_organization_name":"Universitas Syiah Kuala","host_organization_lineage":["https://openalex.org/I187494767"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"pmh:hdl:10068/995279","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10068/995279","pdf_url":null,"source":{"id":"https://openalex.org/S4377196900","display_name":"OpenGrey (Institut de l'Information Scientifique et Technique)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1295345811","host_organization_name":"Institut de l'Information Scientifique et Technique","host_organization_lineage":["https://openalex.org/I1295345811"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"U - Thesis"},{"id":"mag:69551350","doi":null,"is_oa":false,"landing_page_url":"https://etheses.bham.ac.uk/id/eprint/3529/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:uilis.unsyiah.ac.id:50399","doi":null,"is_oa":true,"landing_page_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/50399","pdf_url":"http://etheses.bham.ac.uk/3529/2/Walker_12_PhD.pdf","source":{"id":"https://openalex.org/S4377196378","display_name":"UPT. Syiah Kuala University Library (Syiah Kuala University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187494767","host_organization_name":"Universitas Syiah Kuala","host_organization_lineage":["https://openalex.org/I187494767"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W69551350.pdf","grobid_xml":"https://content.openalex.org/works/W69551350.grobid-xml"},"referenced_works_count":342,"referenced_works":["https://openalex.org/W37775499","https://openalex.org/W95936758","https://openalex.org/W191290535","https://openalex.org/W1482765058","https://openalex.org/W1490963001","https://openalex.org/W1493473843","https://openalex.org/W1501337617","https://openalex.org/W1510063171","https://openalex.org/W1513677807","https://openalex.org/W1533517471","https://openalex.org/W1537015073","https://openalex.org/W1541383277","https://openalex.org/W1562197307","https://openalex.org/W1565823436","https://openalex.org/W1568390176","https://openalex.org/W1569207530","https://openalex.org/W1648593433","https://openalex.org/W1651950734","https://openalex.org/W1771155305","https://openalex.org/W1774858171","https://openalex.org/W1873067475","https://openalex.org/W1902879109","https://openalex.org/W1907484284","https://openalex.org/W1963814263","https://openalex.org/W1963854492","https://openalex.org/W1964081206","https://openalex.org/W1964233348","https://openalex.org/W1964280234","https://openalex.org/W1965723545","https://openalex.org/W1966398231","https://openalex.org/W1967137553","https://openalex.org/W1968093456","https://openalex.org/W1968440551","https://openalex.org/W1976940952","https://openalex.org/W1977127546","https://openalex.org/W1978012243","https://openalex.org/W1981459672","https://openalex.org/W1982746456","https://openalex.org/W1983310397","https://openalex.org/W1983969206","https://openalex.org/W1984009107","https://openalex.org/W1985146880","https://openalex.org/W1985290164","https://openalex.org/W1985826460","https://openalex.org/W1988658871","https://openalex.org/W1988773780","https://openalex.org/W1990084711","https://openalex.org/W1990980729","https://openalex.org/W1991266057","https://openalex.org/W1994151017","https://openalex.org/W1994650341","https://openalex.org/W1994901157","https://openalex.org/W1995773697","https://openalex.org/W1996563641","https://openalex.org/W1997430719","https://openalex.org/W1997688114","https://openalex.org/W1998969528","https://openalex.org/W2000452401","https://openalex.org/W2001159807","https://openalex.org/W2001258296","https://openalex.org/W2001340188","https://openalex.org/W2002208297","https://openalex.org/W2002404925","https://openalex.org/W2003791200","https://openalex.org/W2003922011","https://openalex.org/W2004465491","https://openalex.org/W2006285710","https://openalex.org/W2007032273","https://openalex.org/W2007514658","https://openalex.org/W2008541344","https://openalex.org/W2008557163","https://openalex.org/W2009443603","https://openalex.org/W2009857926","https://openalex.org/W2012053348","https://openalex.org/W2013673508","https://openalex.org/W2016767529","https://openalex.org/W2017211434","https://openalex.org/W2017550531","https://openalex.org/W2017632960","https://openalex.org/W2018348035","https://openalex.org/W2019524734","https://openalex.org/W2019695987","https://openalex.org/W2019777756","https://openalex.org/W2020018240","https://openalex.org/W2021129827","https://openalex.org/W2021362203","https://openalex.org/W2022756254","https://openalex.org/W2022775504","https://openalex.org/W2023022873","https://openalex.org/W2023351030","https://openalex.org/W2023458939","https://openalex.org/W2028246522","https://openalex.org/W2028505689","https://openalex.org/W2028875719","https://openalex.org/W2030262663","https://openalex.org/W2031264299","https://openalex.org/W2031844898","https://openalex.org/W2032072106","https://openalex.org/W2032276880","https://openalex.org/W2033768772","https://openalex.org/W2034790239","https://openalex.org/W2035421116","https://openalex.org/W2036250355","https://openalex.org/W2037952228","https://openalex.org/W2038361153","https://openalex.org/W2038660010","https://openalex.org/W2040857731","https://openalex.org/W2041491387","https://openalex.org/W2043062621","https://openalex.org/W2043539979","https://openalex.org/W2044264310","https://openalex.org/W2044737323","https://openalex.org/W2045187623","https://openalex.org/W2046102646","https://openalex.org/W2046819829","https://openalex.org/W2047665175","https://openalex.org/W2047848539","https://openalex.org/W2048359072","https://openalex.org/W2048915302","https://openalex.org/W2049300468","https://openalex.org/W2050401282","https://openalex.org/W2050672945","https://openalex.org/W2052244380","https://openalex.org/W2052249826","https://openalex.org/W2053039103","https://openalex.org/W2053118942","https://openalex.org/W2053382380","https://openalex.org/W2053869018","https://openalex.org/W2056272044","https://openalex.org/W2056598414","https://openalex.org/W2057199920","https://openalex.org/W2057386387","https://openalex.org/W2057460181","https://openalex.org/W2057805027","https://openalex.org/W2057994540","https://openalex.org/W2058225988","https://openalex.org/W2058646964","https://openalex.org/W2061295375","https://openalex.org/W2061393936","https://openalex.org/W2061463569","https://openalex.org/W2061632771","https://openalex.org/W2061758378","https://openalex.org/W2062205694","https://openalex.org/W2063249351","https://openalex.org/W2063391460","https://openalex.org/W2064208261","https://openalex.org/W2064466932","https://openalex.org/W2065436625","https://openalex.org/W2065535936","https://openalex.org/W2067411979","https://openalex.org/W2067617459","https://openalex.org/W2068142269","https://openalex.org/W2068897967","https://openalex.org/W2070157314","https://openalex.org/W2070793750","https://openalex.org/W2073342423","https://openalex.org/W2073552393","https://openalex.org/W2075907601","https://openalex.org/W2076118036","https://openalex.org/W2078591745","https://openalex.org/W2079490875","https://openalex.org/W2080232689","https://openalex.org/W2081463764","https://openalex.org/W2082320888","https://openalex.org/W2083592664","https://openalex.org/W2083905520","https://openalex.org/W2084949658","https://openalex.org/W2085530184","https://openalex.org/W2085640845","https://openalex.org/W2086069657","https://openalex.org/W2086742737","https://openalex.org/W2088020343","https://openalex.org/W2088479878","https://openalex.org/W2090239878","https://openalex.org/W2090486459","https://openalex.org/W2090562908","https://openalex.org/W2090900329","https://openalex.org/W2091723114","https://openalex.org/W2092448698","https://openalex.org/W2092772070","https://openalex.org/W2092862925","https://openalex.org/W2093531978","https://openalex.org/W2093602249","https://openalex.org/W2095964257","https://openalex.org/W2097377994","https://openalex.org/W2097733438","https://openalex.org/W2097743822","https://openalex.org/W2098052369","https://openalex.org/W2098179994","https://openalex.org/W2098256087","https://openalex.org/W2100189018","https://openalex.org/W2100248836","https://openalex.org/W2100437056","https://openalex.org/W2100553909","https://openalex.org/W2101116242","https://openalex.org/W2101502690","https://openalex.org/W2102012049","https://openalex.org/W2103017472","https://openalex.org/W2103045139","https://openalex.org/W2103076955","https://openalex.org/W2103563884","https://openalex.org/W2103601316","https://openalex.org/W2103974124","https://openalex.org/W2106647095","https://openalex.org/W2106742885","https://openalex.org/W2106757524","https://openalex.org/W2107100887","https://openalex.org/W2107217007","https://openalex.org/W2107534719","https://openalex.org/W2107598685","https://openalex.org/W2108102328","https://openalex.org/W2108995155","https://openalex.org/W2109410583","https://openalex.org/W2109972881","https://openalex.org/W2111083260","https://openalex.org/W2112486895","https://openalex.org/W2113448278","https://openalex.org/W2113665122","https://openalex.org/W2113745932","https://openalex.org/W2114719481","https://openalex.org/W2114786602","https://openalex.org/W2115226431","https://openalex.org/W2115605720","https://openalex.org/W2117297872","https://openalex.org/W2118466320","https://openalex.org/W2118790095","https://openalex.org/W2118835794","https://openalex.org/W2118913969","https://openalex.org/W2119739306","https://openalex.org/W2119911369","https://openalex.org/W2120574072","https://openalex.org/W2120627772","https://openalex.org/W2122324451","https://openalex.org/W2122683221","https://openalex.org/W2122950325","https://openalex.org/W2123106337","https://openalex.org/W2123346488","https://openalex.org/W2123411656","https://openalex.org/W2124201592","https://openalex.org/W2124277850","https://openalex.org/W2124526610","https://openalex.org/W2125409089","https://openalex.org/W2126002765","https://openalex.org/W2126845679","https://openalex.org/W2127346259","https://openalex.org/W2127702552","https://openalex.org/W2129886830","https://openalex.org/W2130359015","https://openalex.org/W2130410032","https://openalex.org/W2130528267","https://openalex.org/W2131050216","https://openalex.org/W2131239997","https://openalex.org/W2131470746","https://openalex.org/W2132110616","https://openalex.org/W2132626013","https://openalex.org/W2132714283","https://openalex.org/W2133243032","https://openalex.org/W2133470612","https://openalex.org/W2134193229","https://openalex.org/W2134359750","https://openalex.org/W2134582937","https://openalex.org/W2134997723","https://openalex.org/W2135056923","https://openalex.org/W2135087298","https://openalex.org/W2135266622","https://openalex.org/W2135523879","https://openalex.org/W2135715423","https://openalex.org/W2135794612","https://openalex.org/W2136207147","https://openalex.org/W2136849575","https://openalex.org/W2137266781","https://openalex.org/W2137520566","https://openalex.org/W2139654861","https://openalex.org/W2140372229","https://openalex.org/W2140632813","https://openalex.org/W2140905749","https://openalex.org/W2144330713","https://openalex.org/W2144876084","https://openalex.org/W2145602937","https://openalex.org/W2145909370","https://openalex.org/W2146167376","https://openalex.org/W2146233513","https://openalex.org/W2146530102","https://openalex.org/W2147136840","https://openalex.org/W2147313414","https://openalex.org/W2147339810","https://openalex.org/W2147372817","https://openalex.org/W2147592763","https://openalex.org/W2148074532","https://openalex.org/W2148239452","https://openalex.org/W2148652353","https://openalex.org/W2148946492","https://openalex.org/W2150118613","https://openalex.org/W2151097126","https://openalex.org/W2151101871","https://openalex.org/W2151947444","https://openalex.org/W2152879728","https://openalex.org/W2153106656","https://openalex.org/W2153523313","https://openalex.org/W2156072759","https://openalex.org/W2156299764","https://openalex.org/W2156394393","https://openalex.org/W2156413520","https://openalex.org/W2157201048","https://openalex.org/W2157795344","https://openalex.org/W2158131645","https://openalex.org/W2158217645","https://openalex.org/W2158756524","https://openalex.org/W2158843303","https://openalex.org/W2159032347","https://openalex.org/W2159594827","https://openalex.org/W2162085688","https://openalex.org/W2162288503","https://openalex.org/W2162898819","https://openalex.org/W2163083747","https://openalex.org/W2163564081","https://openalex.org/W2163587473","https://openalex.org/W2164373019","https://openalex.org/W2165087323","https://openalex.org/W2165512846","https://openalex.org/W2166244290","https://openalex.org/W2166678783","https://openalex.org/W2167467126","https://openalex.org/W2169495754","https://openalex.org/W2169536330","https://openalex.org/W2169677962","https://openalex.org/W2170687947","https://openalex.org/W2171437346","https://openalex.org/W2171996338","https://openalex.org/W2180631471","https://openalex.org/W2182950295","https://openalex.org/W2186980087","https://openalex.org/W2253763905","https://openalex.org/W2254626095","https://openalex.org/W2275576700","https://openalex.org/W2319963574","https://openalex.org/W2321845872","https://openalex.org/W2323449442","https://openalex.org/W2414607147","https://openalex.org/W2442628423","https://openalex.org/W4242253298","https://openalex.org/W4244449355"],"related_works":["https://openalex.org/W2075795841","https://openalex.org/W2041598408","https://openalex.org/W1874198797","https://openalex.org/W2518767583","https://openalex.org/W2071008544","https://openalex.org/W4295512948","https://openalex.org/W2022483910","https://openalex.org/W2070666771","https://openalex.org/W2889037488","https://openalex.org/W2948779703"],"abstract_inverted_index":{"There":[0,174],"is":[1,21],"good":[2],"evidence":[3],"that":[4,26,35,57,167],"high":[5],"dietary":[6,116],"calcium":[7,19,36,117,168],"intake":[8],"reduces":[9],"the":[10,47,58,87,129,136,180,201],"incidence":[11],"of":[12,46,86,122,128,140,143,156,159],"colorectal":[13,32,88],"cancer.":[14],"The":[15],"mechanism":[16],"by":[17,38,115,133,169,183,193],"which":[18,92],"acts":[20,30,37],"unknown.":[22],"It":[23],"was":[24,60,70,126,145,175],"hypothesised":[25],"parathyroid":[27],"hormone":[28],"(PTH)":[29],"on":[31],"epithelium":[33],"and":[34,53,166,190],"suppressing":[39,170],"serum":[40,100],"PTH.":[41,63,134,149],"Real-time":[42],"PCR":[43],"demonstrated":[44],"expression":[45,65,93,139,155],"PTH":[48,81,101,114,163,171,189,194],"receptor":[49],"PTHR1":[50],"in":[51,78,82,94,106,110,153],"normal":[52,95,107],"neoplastic":[54],"colon,":[55],"indicating":[56],"colon":[59],"sensitive":[61],"to":[62,72,80,112],"Gene":[64],"profiling":[66],"using":[67],"oligo-nucleotide":[68],"micro-arrays":[69],"performed":[71],"identify":[73],"genes;":[74],"a)":[75],"Differentially":[76,104],"expressed":[77,105],"response":[79,111],"an":[83],"in-vitro":[84],"model":[85],"epithelium.":[89],"b)":[90],"For":[91],"rectal":[96,108],"mucosa":[97,109],"correlated":[98,147,187],"with":[99,148,188],"level.":[102],"c)":[103],"modulating":[113],"supplementation.":[118],"A":[119],"common":[120],"finding":[121],"all":[123],"three":[124],"studies":[125],"regulation":[127],"wnt":[130],"signalling":[131],"pathway":[132],"In":[135],"in-vivo":[137],"studies,":[138],"genetic":[141,157],"markers":[142,158],"differentiation":[144,165],"negatively":[146,186],"Calcium":[150],"supplementation":[151],"resulted":[152],"increased":[154],"differentiation.":[160,173],"This":[161],"suggests":[162],"inhibits":[164],"promotes":[172],"also":[176],"significant":[177],"overlap":[178],"between":[179],"genes":[181],"changed":[182,192],"calcium,":[184],"those":[185,191],"in-vitro.":[195],"These":[196],"findings":[197],"provide":[198],"support":[199],"for":[200],"stated":[202],"hypotheses.":[203]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
