{"id":"https://openalex.org/W69468859","doi":"https://doi.org/10.1016/b978-0-12-079611-3.50049-5","title":"Human immunodeficiency virus 1 retropepsin","display_name":"Human immunodeficiency virus 1 retropepsin","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W69468859","doi":"https://doi.org/10.1016/b978-0-12-079611-3.50049-5","mag":"69468859"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-12-079611-3.50049-5","doi":"https://doi.org/10.1016/b978-0-12-079611-3.50049-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-079611-3.50049-5","pdf_url":null,"source":{"id":"https://openalex.org/S4306511883","display_name":"Handbook of Proteolytic Enzymes","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Proteolytic Enzymes","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W1567730256","display_name":"Handbook of Proteolytic Enzymes"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009470180","display_name":"Ben M. Dunn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ben M. Dunn","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL 32610-0245, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, University of Florida College of Medicine, Gainesville, FL 32610-0245, USA","institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109085999","display_name":"Mala Rao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3125981224","display_name":"National Chemical Laboratory","ror":"https://ror.org/057mn3690","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2799351866","https://openalex.org/I3125981224","https://openalex.org/I4210134808","https://openalex.org/I66760702"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mala Rao","raw_affiliation_strings":["Division of Biochemical Sciences, National Chemical Laboratory, Pune 411008, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biochemical Sciences, National Chemical Laboratory, Pune 411008, India","institution_ids":["https://openalex.org/I3125981224"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.6831,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.95604396,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"144","last_page":"153"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.5859000086784363,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.5859000086784363,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.17820000648498535,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.051600001752376556,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-1-protease","display_name":"HIV-1 protease","score":0.9210000038146973},{"id":"https://openalex.org/keywords/gag-pol-polyprotein","display_name":"Gag-Pol polyprotein","score":0.9350000023841858},{"id":"https://openalex.org/keywords/cleavage-site","display_name":"cleavage site","score":0.8180000185966492},{"id":"https://openalex.org/keywords/enzyme-stability","display_name":"enzyme stability","score":0.7910000085830688},{"id":"https://openalex.org/keywords/total-synthesis","display_name":"total synthesis","score":0.6740000247955322}],"concepts":[{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.6509206891059875},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5894149541854858},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28644129633903503}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-12-079611-3.50049-5","doi":"https://doi.org/10.1016/b978-0-12-079611-3.50049-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-079611-3.50049-5","pdf_url":null,"source":{"id":"https://openalex.org/S4306511883","display_name":"Handbook of Proteolytic Enzymes","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Proteolytic Enzymes","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6899999976158142}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":227,"referenced_works":["https://openalex.org/W4720620","https://openalex.org/W24925671","https://openalex.org/W59009676","https://openalex.org/W187060429","https://openalex.org/W215579664","https://openalex.org/W288183516","https://openalex.org/W290706038","https://openalex.org/W641468766","https://openalex.org/W946564584","https://openalex.org/W1423590398","https://openalex.org/W1438087379","https://openalex.org/W1496279789","https://openalex.org/W1497441623","https://openalex.org/W1499808375","https://openalex.org/W1514209943","https://openalex.org/W1514273617","https://openalex.org/W1538136349","https://openalex.org/W1547738547","https://openalex.org/W1555843425","https://openalex.org/W1569669680","https://openalex.org/W1574841922","https://openalex.org/W1595757174","https://openalex.org/W1606519969","https://openalex.org/W1621280022","https://openalex.org/W1637218542","https://openalex.org/W1654030133","https://openalex.org/W1865732864","https://openalex.org/W1871968141","https://openalex.org/W1921702285","https://openalex.org/W1932084946","https://openalex.org/W1955630041","https://openalex.org/W1963675638","https://openalex.org/W1964455823","https://openalex.org/W1965349185","https://openalex.org/W1966952510","https://openalex.org/W1968256805","https://openalex.org/W1969406694","https://openalex.org/W1970661613","https://openalex.org/W1971059380","https://openalex.org/W1971222107","https://openalex.org/W1973254785","https://openalex.org/W1973441633","https://openalex.org/W1974964476","https://openalex.org/W1976482662","https://openalex.org/W1976787212","https://openalex.org/W1977249582","https://openalex.org/W1977602725","https://openalex.org/W1977790220","https://openalex.org/W1978424759","https://openalex.org/W1982440127","https://openalex.org/W1983060868","https://openalex.org/W1983247216","https://openalex.org/W1983960184","https://openalex.org/W1983970916","https://openalex.org/W1985636466","https://openalex.org/W1986232807","https://openalex.org/W1986348937","https://openalex.org/W1988431550","https://openalex.org/W1988472873","https://openalex.org/W1988926236","https://openalex.org/W1989161091","https://openalex.org/W1989475707","https://openalex.org/W1989872317","https://openalex.org/W1991448988","https://openalex.org/W1991466551","https://openalex.org/W1991781846","https://openalex.org/W1993686151","https://openalex.org/W1994190560","https://openalex.org/W1995569342","https://openalex.org/W1996835599","https://openalex.org/W1997844736","https://openalex.org/W1998188333","https://openalex.org/W1998805610","https://openalex.org/W1999769355","https://openalex.org/W1999868284","https://openalex.org/W2001532783","https://openalex.org/W2001605595","https://openalex.org/W2002001682","https://openalex.org/W2002254602","https://openalex.org/W2002400107","https://openalex.org/W2003027607","https://openalex.org/W2003955787","https://openalex.org/W2005053829","https://openalex.org/W2006262648","https://openalex.org/W2007717937","https://openalex.org/W2011153626","https://openalex.org/W2011630381","https://openalex.org/W2011897552","https://openalex.org/W2014303214","https://openalex.org/W2014386676","https://openalex.org/W2014723698","https://openalex.org/W2015473272","https://openalex.org/W2015890269","https://openalex.org/W2015953523","https://openalex.org/W2016191309","https://openalex.org/W2019691224","https://openalex.org/W2020625153","https://openalex.org/W2020784172","https://openalex.org/W2020898453","https://openalex.org/W2021749619","https://openalex.org/W2022380758","https://openalex.org/W2023016241","https://openalex.org/W2023133891","https://openalex.org/W2023932631","https://openalex.org/W2024131050","https://openalex.org/W2025152688","https://openalex.org/W2027095884","https://openalex.org/W2027168767","https://openalex.org/W2029777156","https://openalex.org/W2030017358","https://openalex.org/W2030104655","https://openalex.org/W2032471469","https://openalex.org/W2032661950","https://openalex.org/W2035241906","https://openalex.org/W2035341183","https://openalex.org/W2035884087","https://openalex.org/W2036670543","https://openalex.org/W2038636949","https://openalex.org/W2039695661","https://openalex.org/W2039862437","https://openalex.org/W2040249662","https://openalex.org/W2042631213","https://openalex.org/W2042743051","https://openalex.org/W2043073979","https://openalex.org/W2043560498","https://openalex.org/W2043925231","https://openalex.org/W2044028507","https://openalex.org/W2044422624","https://openalex.org/W2045241078","https://openalex.org/W2045408268","https://openalex.org/W2045519662","https://openalex.org/W2046639437","https://openalex.org/W2047210077","https://openalex.org/W2047558831","https://openalex.org/W2047816735","https://openalex.org/W2049972125","https://openalex.org/W2050498291","https://openalex.org/W2050930008","https://openalex.org/W2054728806","https://openalex.org/W2055329982","https://openalex.org/W2055478901","https://openalex.org/W2059176877","https://openalex.org/W2059559197","https://openalex.org/W2060099174","https://openalex.org/W2062558371","https://openalex.org/W2065143546","https://openalex.org/W2065631521","https://openalex.org/W2066062917","https://openalex.org/W2069344331","https://openalex.org/W2071421333","https://openalex.org/W2072379455","https://openalex.org/W2072822306","https://openalex.org/W2073302617","https://openalex.org/W2076304758","https://openalex.org/W2077195277","https://openalex.org/W2079341971","https://openalex.org/W2083657154","https://openalex.org/W2084387914","https://openalex.org/W2085318243","https://openalex.org/W2085562576","https://openalex.org/W2087478505","https://openalex.org/W2087876594","https://openalex.org/W2089003093","https://openalex.org/W2089433975","https://openalex.org/W2090828745","https://openalex.org/W2092093169","https://openalex.org/W2093217552","https://openalex.org/W2093751313","https://openalex.org/W2094351443","https://openalex.org/W2094643920","https://openalex.org/W2095300338","https://openalex.org/W2097168605","https://openalex.org/W2097183660","https://openalex.org/W2098967863","https://openalex.org/W2100173291","https://openalex.org/W2101936319","https://openalex.org/W2103073125","https://openalex.org/W2106571163","https://openalex.org/W2108640116","https://openalex.org/W2112857740","https://openalex.org/W2115172215","https://openalex.org/W2117149353","https://openalex.org/W2120118559","https://openalex.org/W2121882125","https://openalex.org/W2122087219","https://openalex.org/W2123166384","https://openalex.org/W2124219170","https://openalex.org/W2125272995","https://openalex.org/W2127137755","https://openalex.org/W2130082288","https://openalex.org/W2131046434","https://openalex.org/W2131480593","https://openalex.org/W2132185205","https://openalex.org/W2132972976","https://openalex.org/W2133135980","https://openalex.org/W2134666489","https://openalex.org/W2136371489","https://openalex.org/W2138593751","https://openalex.org/W2139235397","https://openalex.org/W2140763734","https://openalex.org/W2142419484","https://openalex.org/W2142640685","https://openalex.org/W2143794399","https://openalex.org/W2145680826","https://openalex.org/W2145758010","https://openalex.org/W2150383590","https://openalex.org/W2152989668","https://openalex.org/W2153150300","https://openalex.org/W2154901255","https://openalex.org/W2160276605","https://openalex.org/W2160893224","https://openalex.org/W2161027162","https://openalex.org/W2163493349","https://openalex.org/W2165732545","https://openalex.org/W2168918508","https://openalex.org/W2269193534","https://openalex.org/W2400184889","https://openalex.org/W2953157937","https://openalex.org/W2963575425","https://openalex.org/W4235305170","https://openalex.org/W4236479494","https://openalex.org/W4239840825","https://openalex.org/W4240239309","https://openalex.org/W4246673034","https://openalex.org/W6608616956","https://openalex.org/W6656569601","https://openalex.org/W6766695128"],"related_works":["https://openalex.org/W2151116772","https://openalex.org/W2115869555","https://openalex.org/W70862341","https://openalex.org/W2089003093","https://openalex.org/W2054728806","https://openalex.org/W2121882125","https://openalex.org/W7098051953","https://openalex.org/W1594139320","https://openalex.org/W1892408656","https://openalex.org/W1995251281"],"abstract_inverted_index":null,"counts_by_year":[{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}
