{"id":"https://openalex.org/W69049961","doi":null,"title":"[Value and dangers of indomethacin used in pregnancy. Apropos of 304 treated patients].","display_name":"[Value and dangers of indomethacin used in pregnancy. Apropos of 304 treated patients].","publication_year":1988,"publication_date":"1988-01-01","ids":{"openalex":"https://openalex.org/W69049961","mag":"69049961","pmid":"https://pubmed.ncbi.nlm.nih.gov/3280651"},"language":"fr","primary_location":{"id":"pmid:3280651","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3280651","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal de gynecologie, obstetrique et biologie de la reproduction","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112090791","display_name":"L. Marpeau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"L Marpeau","raw_affiliation_strings":["Clinique gyn\u00e9cologique et obst\u00e9tricale, H\u00f4pital Saint-Antoine, Paris"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinique gyn\u00e9cologique et obst\u00e9tricale, H\u00f4pital Saint-Antoine, Paris","institution_ids":["https://openalex.org/I4210102928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020122306","display_name":"J Keskes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Keskes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007198969","display_name":"O Vincenti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"O Vincenti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"F Boyer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Boyer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061172647","display_name":"J. Bouillie","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Bouillie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054735492","display_name":"Alain Pigne","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Pign\u00e9","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5054130334","display_name":"J Barrat","orcid":"https://orcid.org/0000-0002-7426-0249","observed_orcids":["https://orcid.org/0000-0002-7426-0249"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Barrat","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.203,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.7608505,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":"1","first_page":"115","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11290","display_name":"Preterm Birth and Chorioamnionitis","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11290","display_name":"Preterm Birth and Chorioamnionitis","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.02930000051856041,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10453","display_name":"Maternal and Perinatal Health Interventions","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/indomethacin","display_name":"indomethacin","score":1.0},{"id":"https://openalex.org/keywords/threatened-preterm-labor","display_name":"threatened preterm labor","score":0.8600000143051147},{"id":"https://openalex.org/keywords/tocolysis","display_name":"tocolysis","score":0.7540000081062317},{"id":"https://openalex.org/keywords/beta-mimetics","display_name":"beta-mimetics","score":0.6430000066757202},{"id":"https://openalex.org/keywords/neonatal-renal-failure","display_name":"neonatal renal failure","score":0.8059999942779541},{"id":"https://openalex.org/keywords/oligohydramnios","display_name":"oligohydramnios","score":0.984000027179718},{"id":"https://openalex.org/keywords/intrauterine-growth-restriction","display_name":"fetal growth restriction","score":0.8479999899864197}],"concepts":[{"id":"https://openalex.org/C2776310010","wikidata":"https://www.wikidata.org/wiki/Q3281781","display_name":"Maldevelopment","level":2,"score":0.8724410533905029},{"id":"https://openalex.org/C2781056747","wikidata":"https://www.wikidata.org/wiki/Q1144406","display_name":"Oligohydramnios","level":4,"score":0.7712299227714539},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7077474594116211},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.6729956865310669},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.6474893689155579},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.500762939453125},{"id":"https://openalex.org/C3020705096","wikidata":"https://www.wikidata.org/wiki/Q5253500","display_name":"Growth retardation","level":3,"score":0.4379580020904541},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33618611097335815},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000033","descriptor_name":"Abortion, Threatened","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004374","descriptor_name":"Ductus Arteriosus, Patent","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005313","descriptor_name":"Fetal Death","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007213","descriptor_name":"Indomethacin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D007213","descriptor_name":"Indomethacin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007213","descriptor_name":"Indomethacin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007236","descriptor_name":"Infant, Small for Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010547","descriptor_name":"Persistent Fetal Circulation Syndrome","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058186","descriptor_name":"Acute Kidney Injury","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3280651","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3280651","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal de gynecologie, obstetrique et biologie de la reproduction","raw_type":"English Abstract"},{"id":"mag:69049961","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3280651","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W20214180","https://openalex.org/W105266765","https://openalex.org/W2410267983","https://openalex.org/W2008389320","https://openalex.org/W2077288549","https://openalex.org/W2040188138","https://openalex.org/W2101457385","https://openalex.org/W2317472642","https://openalex.org/W2052153192","https://openalex.org/W2042893661"],"abstract_inverted_index":{"When":[0],"Indomethacin":[1,100],"in":[2,58,107],"a":[3],"dosage":[4,60],"of":[5,18,49,113],"175":[6],"mg/day":[7],"was":[8,85],"used":[9,61],"to":[10,33],"treat":[11],"threatened":[12],"premature":[13],"labour":[14],"more":[15,95],"than":[16,96],"70%":[17],"cases":[19],"carried":[20],"on":[21,127],"until":[22],"37":[23],"weeks.":[24],"This":[25],"treatment":[26,32,84,89,123],"therefore":[27],"is":[28,74,118],"an":[29],"interesting":[30],"alternative":[31],"beta-mimetics":[34],"whose":[35],"the":[36,46,50,56,59,65,114],"maternal":[37],"side":[38],"effects":[39,57],"can":[40,105],"be":[41,70,92],"serious.":[42],"As":[43],"far":[44],"as":[45],"cardiovascular":[47],"systems":[48],"fetus":[51],"and":[52,103,111],"neonate":[53],"are":[54,62],"concerned":[55],"negligible.":[63],"On":[64],"other":[66],"hand":[67],"there":[68],"may":[69],"renal":[71],"failure":[72],"which":[73],"transitory":[75],"at":[76],"birth":[77],"when":[78],"delivery":[79],"has":[80,124],"taken":[81],"place":[82,109],"while":[83],"going":[86],"on.":[87],"The":[88],"should":[90],"not":[91,119],"prolonged":[93],"for":[94],"three":[97],"weeks":[98],"because":[99],"causes":[101],"oligohydramnios":[102],"this":[104,122],"cause":[106],"its":[108],"malpositions":[110],"maldevelopment":[112],"lungs.":[115],"Finally,":[116],"it":[117],"certain":[120],"whether":[121],"any":[125],"effect":[126],"fetal":[128],"growth":[129],"causing":[130],"diminished":[131],"growth,":[132],"possibly.":[133]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}