{"id":"https://openalex.org/W6893813352","doi":"https://doi.org/10.5281/zenodo.5652114","title":"T Cell Receptor Beta Germline Variability is Revealed by Inference From Repertoire Data","display_name":"T Cell Receptor Beta Germline Variability is Revealed by Inference From Repertoire Data","publication_year":2021,"publication_date":"2021-11-07","ids":{"openalex":"https://openalex.org/W6893813352","doi":"https://doi.org/10.5281/zenodo.5652114"},"language":"en","primary_location":{"id":"pmh:oai:zenodo.org:5652115","doi":null,"is_oa":true,"landing_page_url":"https://zenodo.org/record/5652115","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://zenodo.org/record/5652115","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110834634","display_name":"Aviv Omer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Omer, Aviv","raw_affiliation_strings":["Faculty of Engineering, Bar Ilan University & Bar Ilan institute of nanotechnology and advanced materials, Bar Ilan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Engineering, Bar Ilan University & Bar Ilan institute of nanotechnology and advanced materials, Bar Ilan University","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053964003","display_name":"Ayelet Peres","orcid":"https://orcid.org/0000-0002-0188-7315","observed_orcids":["https://orcid.org/0000-0002-0188-7315"]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Peres, Ayelet","raw_affiliation_strings":["Faculty of Engineering, Bar Ilan University & Bar Ilan institute of nanotechnology and advanced materials, Bar Ilan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Engineering, Bar Ilan University & Bar Ilan institute of nanotechnology and advanced materials, Bar Ilan University","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013367192","display_name":"Oscar L. Rodriguez","orcid":"https://orcid.org/0000-0002-4587-6124","observed_orcids":["https://orcid.org/0000-0002-4587-6124"]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rodriguez, Oscar L","raw_affiliation_strings":["Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Watson, Corey T","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Watson, Corey T","raw_affiliation_strings":["Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001972889","display_name":"William Lees","orcid":"https://orcid.org/0000-0001-9834-6840","observed_orcids":["https://orcid.org/0000-0001-9834-6840"]},"institutions":[{"id":"https://openalex.org/I4210157240","display_name":"Institute of Structural and Molecular Biology","ror":"https://ror.org/05wsetc54","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210157240","https://openalex.org/I45129253","https://openalex.org/I98259816"]},{"id":"https://openalex.org/I98259816","display_name":"Birkbeck, University of London","ror":"https://ror.org/02mb95055","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I98259816"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lees, William","raw_affiliation_strings":["Institute of Structural and Molecular Biology, Birkbeck College, University of London"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Structural and Molecular Biology, Birkbeck College, University of London","institution_ids":["https://openalex.org/I4210157240","https://openalex.org/I98259816"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046033939","display_name":"Pazit Polak","orcid":"https://orcid.org/0000-0001-8363-0734","observed_orcids":["https://orcid.org/0000-0001-8363-0734"]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Polak, Pazit","raw_affiliation_strings":["Faculty of Engineering, Bar Ilan University & Bar Ilan institute of nanotechnology and advanced materials, Bar Ilan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Engineering, Bar Ilan University & Bar Ilan institute of nanotechnology and advanced materials, Bar Ilan University","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018874456","display_name":"Andrew M. Collins","orcid":"https://orcid.org/0000-0001-8385-6792","observed_orcids":["https://orcid.org/0000-0001-8385-6792"]},"institutions":[{"id":"https://openalex.org/I31746571","display_name":"UNSW Sydney","ror":"https://ror.org/03r8z3t63","country_code":"AU","type":"education","lineage":["https://openalex.org/I31746571"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Collins, Andrew M","raw_affiliation_strings":["School of Biotechnology and Biomedical Sciences, University of New South Wales"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biotechnology and Biomedical Sciences, University of New South Wales","institution_ids":["https://openalex.org/I31746571"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5084475280","display_name":"Gur Yaari","orcid":"https://orcid.org/0000-0001-9311-9884","observed_orcids":["https://orcid.org/0000-0001-9311-9884"]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Yaari, Gur","raw_affiliation_strings":["Faculty of Engineering, Bar Ilan University & Bar Ilan institute of nanotechnology and advanced materials, Bar Ilan University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Engineering, Bar Ilan University & Bar Ilan institute of nanotechnology and advanced materials, Bar Ilan University","institution_ids":["https://openalex.org/I13955877"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0934,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.3816185,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":true,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8246999979019165,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8246999979019165,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.039500001817941666,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tcr-beta-chain","display_name":"T cell receptor beta chain","score":0.9259999990463257},{"id":"https://openalex.org/keywords/tcr-repertoire","display_name":"T cell receptor repertoire","score":0.9049999713897705},{"id":"https://openalex.org/keywords/t-cell-receptor-gene-rearrangement","display_name":"T-cell receptor gene rearrangement","score":0.45100000500679016}],"concepts":[{"id":"https://openalex.org/C109825262","wikidata":"https://www.wikidata.org/wiki/Q1139164","display_name":"Germline","level":3,"score":0.8258000016212463},{"id":"https://openalex.org/C2778473898","wikidata":"https://www.wikidata.org/wiki/Q2145110","display_name":"Repertoire","level":2,"score":0.6940000057220459},{"id":"https://openalex.org/C19317047","wikidata":"https://www.wikidata.org/wiki/Q412037","display_name":"T-cell receptor","level":4,"score":0.6654000282287598},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6459000110626221},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.6226999759674072},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5083000063896179},{"id":"https://openalex.org/C2776174256","wikidata":"https://www.wikidata.org/wiki/Q830842","display_name":"BETA (programming language)","level":2,"score":0.4399999976158142},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3889999985694885},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.3517000079154968},{"id":"https://openalex.org/C1547928","wikidata":"https://www.wikidata.org/wiki/Q1660177","display_name":"Immunogenetics","level":3,"score":0.33570000529289246},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.33219999074935913},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.3312999904155731},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.27900001406669617},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.27320000529289246},{"id":"https://openalex.org/C2776760102","wikidata":"https://www.wikidata.org/wiki/Q5139990","display_name":"Code (set theory)","level":3,"score":0.26840001344680786},{"id":"https://openalex.org/C64943373","wikidata":"https://www.wikidata.org/wiki/Q2651003","display_name":"Alpha (finance)","level":4,"score":0.25999999046325684},{"id":"https://openalex.org/C198370458","wikidata":"https://www.wikidata.org/wiki/Q586459","display_name":"Type inference","level":3,"score":0.25519999861717224}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:zenodo.org:5652115","doi":null,"is_oa":true,"landing_page_url":"https://zenodo.org/record/5652115","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:zenodo.org:5652127","doi":null,"is_oa":true,"landing_page_url":"https://zenodo.org/record/5652127","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"doi:10.5281/zenodo.5652114","doi":"https://doi.org/10.5281/zenodo.5652114","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.5652114","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.5281/zenodo.5652115","doi":"https://doi.org/10.5281/zenodo.5652115","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.5652115","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.5281/zenodo.5652127","doi":"https://doi.org/10.5281/zenodo.5652127","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.5652127","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"pmh:oai:zenodo.org:5652115","doi":null,"is_oa":true,"landing_page_url":"https://zenodo.org/record/5652115","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5493932354","display_name":"ARCHITECTURE AND TOOLS FOR THE QUERY OF ANTIBODY AND T-CELL RECEPTOR SEQUENCING DATA REPOSITORIES FOR ENABLING IMPROVED PERSONALIZED MEDICINE AND IMMUNOTHERAPY","funder_award_id":"825821","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2138968719","https://openalex.org/W6902004205","https://openalex.org/W6911200136","https://openalex.org/W6949550657","https://openalex.org/W6931617811","https://openalex.org/W4318939665","https://openalex.org/W2547929624","https://openalex.org/W136951974","https://openalex.org/W6928998570","https://openalex.org/W6894119022"],"abstract_inverted_index":{"TCR":[0],"germline":[1],"inference":[2],"pipeline":[3],"code,":[4],"and":[5,9],"the":[6,12],"data,":[7],"figures,":[8],"code":[10],"for":[11],"analysis":[13],"of":[14],"\"T":[15],"Cell":[16],"Receptor":[17],"Beta":[18],"Germline":[19],"Variability":[20],"is":[21],"Revealed":[22],"by":[23],"Inference":[24],"From":[25],"Repertoire":[26],"Data\"":[27],"article":[28]},"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}