{"id":"https://openalex.org/W67784875","doi":"https://doi.org/10.1023/a:1023635510363","title":"Caspases as Regulators of Apoptosis and Other Cell Functions","display_name":"Caspases as Regulators of Apoptosis and Other Cell Functions","publication_year":2003,"publication_date":"2003-04-01","ids":{"openalex":"https://openalex.org/W67784875","doi":"https://doi.org/10.1023/a:1023635510363","mag":"67784875","pmid":"https://pubmed.ncbi.nlm.nih.gov/12765517"},"language":"en","primary_location":{"id":"doi:10.1023/a:1023635510363","doi":"https://doi.org/10.1023/a:1023635510363","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1023635510363","pdf_url":null,"source":{"id":"https://openalex.org/S71215691","display_name":"Biochemistry (Moscow)","issn_l":"0006-2979","issn":["0006-2979","0320-9725","1608-3040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry (Moscow)","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077319617","display_name":"Alex A. Philchenkov","orcid":"https://orcid.org/0000-0001-5315-4490","observed_orcids":["https://orcid.org/0000-0001-5315-4490"]},"institutions":[{"id":"https://openalex.org/I149851306","display_name":"National Academy of Sciences of Ukraine","ror":"https://ror.org/00je4t102","country_code":"UA","type":"government","lineage":["https://openalex.org/I149851306"]},{"id":"https://openalex.org/I4210113428","display_name":"R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology","ror":"https://ror.org/02ff7k505","country_code":"UA","type":"facility","lineage":["https://openalex.org/I149851306","https://openalex.org/I4210113428"]}],"countries":["UA"],"is_corresponding":true,"raw_author_name":"A. A. Philchenkov","raw_affiliation_strings":["Kavetsky Institute of Experimental Pathology, Oncology, and Radiobiology, National Academy of Sciences of Ukraine, Kiev, 03022, Ukraine. butenko@onconet.kiev.ua","National Academy of Sciences of Ukraine, Vasilkovskaya ul. 45, Kavetsky Institute of Experimental Pathology, Oncology, and Radiobiology, Kiev, Ukraine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kavetsky Institute of Experimental Pathology, Oncology, and Radiobiology, National Academy of Sciences of Ukraine, Kiev, 03022, Ukraine. butenko@onconet.kiev.ua","institution_ids":["https://openalex.org/I149851306","https://openalex.org/I4210113428"]},{"raw_affiliation_string":"National Academy of Sciences of Ukraine, Vasilkovskaya ul. 45, Kavetsky Institute of Experimental Pathology, Oncology, and Radiobiology, Kiev, Ukraine","institution_ids":["https://openalex.org/I149851306","https://openalex.org/I4210113428"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5077319617"],"corresponding_institution_ids":["https://openalex.org/I149851306","https://openalex.org/I4210113428"],"apc_list":null,"apc_paid":null,"fwci":0.3935,"has_fulltext":false,"cited_by_count":61,"citation_normalized_percentile":{"value":0.34381898,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"68","issue":"4","first_page":"365","last_page":"376"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13637","display_name":"Calpain Protease Function and Regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caspases","display_name":"caspases","score":1.0},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cysteine-protease","display_name":"cysteine protease","score":0.9929999709129333},{"id":"https://openalex.org/keywords/caspase-substrates","display_name":"caspase substrates","score":0.8669999837875366},{"id":"https://openalex.org/keywords/caspase-inhibitors","display_name":"caspase inhibitors","score":0.9990000128746033},{"id":"https://openalex.org/keywords/endopeptidase","display_name":"endopeptidase","score":0.8299999833106995}],"concepts":[{"id":"https://openalex.org/C98424977","wikidata":"https://www.wikidata.org/wiki/Q25805","display_name":"Caspase","level":4,"score":0.9273203611373901},{"id":"https://openalex.org/C182220744","wikidata":"https://www.wikidata.org/wiki/Q7251226","display_name":"Proteases","level":3,"score":0.8518513441085815},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.7724419832229614},{"id":"https://openalex.org/C163421366","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Intrinsic apoptosis","level":5,"score":0.6764996647834778},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6282428503036499},{"id":"https://openalex.org/C2779201268","wikidata":"https://www.wikidata.org/wiki/Q186474","display_name":"Cysteine","level":3,"score":0.5673802495002747},{"id":"https://openalex.org/C155863897","wikidata":"https://www.wikidata.org/wiki/Q14913269","display_name":"Caspase 2","level":5,"score":0.46981245279312134},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4140198528766632},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35627079010009766},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.34046870470046997},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2524718940258026},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.19262906908988953}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013379","descriptor_name":"Substrate Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015971","descriptor_name":"Gene Expression Regulation, Enzymologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020169","descriptor_name":"Caspases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020169","descriptor_name":"Caspases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1023/a:1023635510363","doi":"https://doi.org/10.1023/a:1023635510363","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1023635510363","pdf_url":null,"source":{"id":"https://openalex.org/S71215691","display_name":"Biochemistry (Moscow)","issn_l":"0006-2979","issn":["0006-2979","0320-9725","1608-3040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry (Moscow)","raw_type":"journal-article"},{"id":"pmid:12765517","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12765517","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry. Biokhimiia","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":118,"referenced_works":["https://openalex.org/W94415631","https://openalex.org/W1492864494","https://openalex.org/W1500396877","https://openalex.org/W1530629109","https://openalex.org/W1566777539","https://openalex.org/W1591022300","https://openalex.org/W1595797136","https://openalex.org/W1604401260","https://openalex.org/W1604645679","https://openalex.org/W1644794975","https://openalex.org/W1662168393","https://openalex.org/W1662899239","https://openalex.org/W1804620564","https://openalex.org/W1829810608","https://openalex.org/W1845459216","https://openalex.org/W1874876720","https://openalex.org/W1879738374","https://openalex.org/W1932119280","https://openalex.org/W1961680179","https://openalex.org/W1964297184","https://openalex.org/W1966176339","https://openalex.org/W1968262266","https://openalex.org/W1971602494","https://openalex.org/W1972364463","https://openalex.org/W1974670485","https://openalex.org/W1975155851","https://openalex.org/W1982687089","https://openalex.org/W1984028519","https://openalex.org/W1986331996","https://openalex.org/W1990341204","https://openalex.org/W1990735654","https://openalex.org/W1996357925","https://openalex.org/W1996807274","https://openalex.org/W2003107854","https://openalex.org/W2003435676","https://openalex.org/W2003472250","https://openalex.org/W2007939817","https://openalex.org/W2010275946","https://openalex.org/W2010474466","https://openalex.org/W2013583594","https://openalex.org/W2015306970","https://openalex.org/W2015965270","https://openalex.org/W2017728303","https://openalex.org/W2019294906","https://openalex.org/W2019631673","https://openalex.org/W2022393030","https://openalex.org/W2024527294","https://openalex.org/W2028987210","https://openalex.org/W2029962841","https://openalex.org/W2033403762","https://openalex.org/W2033733508","https://openalex.org/W2034213169","https://openalex.org/W2034925111","https://openalex.org/W2035886109","https://openalex.org/W2036568037","https://openalex.org/W2038212272","https://openalex.org/W2039344765","https://openalex.org/W2041022386","https://openalex.org/W2042779695","https://openalex.org/W2043671725","https://openalex.org/W2045114648","https://openalex.org/W2047571097","https://openalex.org/W2048666761","https://openalex.org/W2049608177","https://openalex.org/W2060925403","https://openalex.org/W2061497413","https://openalex.org/W2062014088","https://openalex.org/W2064950130","https://openalex.org/W2070020247","https://openalex.org/W2070479140","https://openalex.org/W2071987213","https://openalex.org/W2074678011","https://openalex.org/W2075226068","https://openalex.org/W2075761806","https://openalex.org/W2083560313","https://openalex.org/W2086883099","https://openalex.org/W2087450028","https://openalex.org/W2090397581","https://openalex.org/W2091267060","https://openalex.org/W2104642445","https://openalex.org/W2105428498","https://openalex.org/W2108362910","https://openalex.org/W2109965462","https://openalex.org/W2112146702","https://openalex.org/W2112795540","https://openalex.org/W2117074998","https://openalex.org/W2118644071","https://openalex.org/W2118906507","https://openalex.org/W2119502087","https://openalex.org/W2120492514","https://openalex.org/W2133425838","https://openalex.org/W2135662322","https://openalex.org/W2137371640","https://openalex.org/W2140297626","https://openalex.org/W2144701362","https://openalex.org/W2146226667","https://openalex.org/W2149605526","https://openalex.org/W2150130743","https://openalex.org/W2153689486","https://openalex.org/W2156179144","https://openalex.org/W2157999078","https://openalex.org/W2160100702","https://openalex.org/W2162172222","https://openalex.org/W2162295519","https://openalex.org/W2162585479","https://openalex.org/W2162653594","https://openalex.org/W2171483351","https://openalex.org/W2315815984","https://openalex.org/W2316070165","https://openalex.org/W2329147463","https://openalex.org/W2406899882","https://openalex.org/W2412248564","https://openalex.org/W2469778375","https://openalex.org/W2614993331","https://openalex.org/W3171781738","https://openalex.org/W4232748180","https://openalex.org/W4247772431","https://openalex.org/W6600659201"],"related_works":["https://openalex.org/W403527634","https://openalex.org/W2088238268","https://openalex.org/W2135662322","https://openalex.org/W4381715703","https://openalex.org/W2914551822","https://openalex.org/W2026988411","https://openalex.org/W2076585497","https://openalex.org/W2051916700","https://openalex.org/W4288059662","https://openalex.org/W2412210352"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
