{"id":"https://openalex.org/W67596369","doi":null,"title":"Sequential expression of glutathione-S-transferase isoenzymes during hair growth phases in mice and their relationship to caldesmon, phosphotyrosinase and VIP receptor protein.","display_name":"Sequential expression of glutathione-S-transferase isoenzymes during hair growth phases in mice and their relationship to caldesmon, phosphotyrosinase and VIP receptor protein.","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W67596369","mag":"67596369","pmid":"https://pubmed.ncbi.nlm.nih.gov/7756742"},"language":"en","primary_location":{"id":"pmid:7756742","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7756742","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histology and histopathology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038415410","display_name":"Uwe Wollina","orcid":"https://orcid.org/0000-0001-5933-2913","observed_orcids":["https://orcid.org/0000-0001-5933-2913"]},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"U Wollina","raw_affiliation_strings":["Department of Dermatology, Friedrich-Schiller-University of Jena, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Friedrich-Schiller-University of Jena, Germany","institution_ids":["https://openalex.org/I76198965"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082322510","display_name":"Ralf Paus","orcid":"https://orcid.org/0000-0002-3492-9358","observed_orcids":["https://orcid.org/0000-0002-3492-9358"]},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"R Paus","raw_affiliation_strings":["Friedrich-Schiller University Jena"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Friedrich-Schiller University Jena","institution_ids":["https://openalex.org/I76198965"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041791793","display_name":"S. Feldrappe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76198965","display_name":"Friedrich Schiller University Jena","ror":"https://ror.org/05qpz1x62","country_code":"DE","type":"education","lineage":["https://openalex.org/I76198965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"S Feldrappe","raw_affiliation_strings":["Friedrich-Schiller University Jena"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Friedrich-Schiller University Jena","institution_ids":["https://openalex.org/I76198965"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I76198965"],"apc_list":null,"apc_paid":null,"fwci":1.4584,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.79107807,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"10","issue":"1","first_page":"39","last_page":"45"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11167","display_name":"Hair Growth and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11167","display_name":"Hair Growth and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12187","display_name":"Glutathione Transferases and Polymorphisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hair-cycle","display_name":"hair cycle","score":0.7480000257492065},{"id":"https://openalex.org/keywords/anagen","display_name":"anagen","score":0.9509999752044678},{"id":"https://openalex.org/keywords/telogen","display_name":"telogen","score":0.8510000109672546},{"id":"https://openalex.org/keywords/hair-follicle","display_name":"hair follicle","score":0.6690000295639038},{"id":"https://openalex.org/keywords/caldesmon","display_name":"caldesmon","score":0.800000011920929},{"id":"https://openalex.org/keywords/vip-receptors","display_name":"VIP receptors","score":0.9589999914169312},{"id":"https://openalex.org/keywords/vasoactive-intestinal-peptide","display_name":"vasoactive intestinal peptide","score":0.8389999866485596},{"id":"https://openalex.org/keywords/inner-root-sheath","display_name":"inner root sheath","score":0.8889999985694885},{"id":"https://openalex.org/keywords/sebaceous-glands","display_name":"sebaceous glands","score":0.878000020980835},{"id":"https://openalex.org/keywords/neuropeptides","display_name":"neuropeptides","score":0.7310000061988831},{"id":"https://openalex.org/keywords/hair-follicle-differentiation","display_name":"hair follicle differentiation","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C2777216303","wikidata":"https://www.wikidata.org/wiki/Q866324","display_name":"Hair follicle","level":2,"score":0.6875759363174438},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6874494552612305},{"id":"https://openalex.org/C2991961867","wikidata":"https://www.wikidata.org/wiki/Q866324","display_name":"Hair cycle","level":3,"score":0.661536455154419},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6099705100059509},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6050955653190613},{"id":"https://openalex.org/C2779360546","wikidata":"https://www.wikidata.org/wiki/Q5019078","display_name":"Caldesmon","level":4,"score":0.5635508298873901},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.5295841693878174},{"id":"https://openalex.org/C2779688582","wikidata":"https://www.wikidata.org/wiki/Q7112036","display_name":"Outer root sheath","level":3,"score":0.5223285555839539},{"id":"https://openalex.org/C119795356","wikidata":"https://www.wikidata.org/wiki/Q407801","display_name":"Isozyme","level":3,"score":0.45921942591667175},{"id":"https://openalex.org/C2779185020","wikidata":"https://www.wikidata.org/wiki/Q16968791","display_name":"Inner root sheath","level":4,"score":0.44984954595565796},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.44865885376930237},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.16566377878189087},{"id":"https://openalex.org/C29688787","wikidata":"https://www.wikidata.org/wiki/Q409145","display_name":"Calmodulin","level":3,"score":0.15282276272773743},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10494154691696167},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.08326593041419983},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002148","descriptor_name":"Calmodulin-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005982","descriptor_name":"Glutathione Transferase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006197","descriptor_name":"Hair","qualifier_ui":"Q000033","qualifier_name":"anatomy & histology","is_major_topic":false},{"descriptor_ui":"D006197","descriptor_name":"Hair","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D006197","descriptor_name":"Hair","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017027","descriptor_name":"Protein Tyrosine Phosphatases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018005","descriptor_name":"Receptors, Vasoactive Intestinal Peptide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:7756742","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7756742","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Histology and histopathology","raw_type":"Journal Article"},{"id":"mag:67596369","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7756742","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W133299236","https://openalex.org/W1969040012","https://openalex.org/W1980332250","https://openalex.org/W1980551609","https://openalex.org/W2052374913","https://openalex.org/W2056291109","https://openalex.org/W2074959477","https://openalex.org/W2078238098","https://openalex.org/W2084368791","https://openalex.org/W2125732000","https://openalex.org/W2160421139","https://openalex.org/W2300853896","https://openalex.org/W2409966479","https://openalex.org/W2523610615"],"related_works":["https://openalex.org/W7061771809","https://openalex.org/W2089444727","https://openalex.org/W3133096570","https://openalex.org/W2468061886","https://openalex.org/W2052374913","https://openalex.org/W6981723039","https://openalex.org/W2606732618","https://openalex.org/W7206452145","https://openalex.org/W7056451512","https://openalex.org/W2032110415"],"abstract_inverted_index":{"The":[0],"hair":[1,43,109,176,192],"follicle":[2,193],"is":[3,16],"a":[4,7,170,182],"structure":[5],"showing":[6],"very":[8],"unique":[9],"cycling":[10],"of":[11,21,55,68,75,87,172,185],"its":[12],"epithelial":[13],"components.":[14],"It":[15,93],"innervated":[17],"by":[18,48,91],"an":[19],"abundance":[20],"peptidergic":[22],"nerves,":[23],"and":[24,62,70,72,82,106,142,179],"neuroendocrine":[25],"cells":[26],"occur":[27],"within":[28,128,152],"the":[29,53,66,76,103,107,116,124,129,153,163,190],"epithelium":[30],"or":[31],"in":[32,65,102,115,139,145,180,188],"close":[33],"proximity":[34],"to":[35,59,175,198],"it.":[36],"Recently,":[37],"it":[38],"has":[39],"been":[40],"suggested":[41],"that":[42,96],"growth":[44,69,194],"may":[45],"be":[46],"regulated":[47],"neuropeptides.":[49],"We":[50],"therefore":[51],"investigated":[52],"relationship":[54,171],"VIP":[56,148],"receptor":[57,149,187],"expression":[58,137,174],"intracellular":[60],"phosphotyrosinase":[61,136],"caldesmon":[63],"involved":[64],"control":[67],"differentiation":[71],"metabolizing":[73],"isoenzymes":[74,98],"glutathione-S-transferase":[77],"(GST)":[78],"family":[79],"alpha,":[80],"mu,":[81],"pi":[83],"during":[84,123,156,162,195],"induced":[85],"anagen":[86,126,157,196],"C57":[88],"BI-6":[89],"mice":[90],"immunohistochemistry.":[92],"was":[94,121,133,150,160],"demonstrated":[95],"GST":[97],"were":[99],"expressed":[100,151],"sequentially":[101],"bulge":[104,130,154],"area":[105,155],"inner":[108],"root":[110],"sheath":[111],"as":[112,114,132],"well":[113],"sebaceous":[117],"gland":[118],"epithelium.":[119],"Caldesmon":[120],"present":[122],"early":[125],"phases":[127,178],"region,":[131],"phosphotyrosinase.":[134],"However,":[135],"decreased":[138],"late":[140],"anagen,":[141],"recovered":[143],"again":[144],"post-epilation":[146],"telogen.":[147],"V,":[158],"but":[159],"absent":[161],"other":[164],"cycle":[165,177],"phases.":[166],"These":[167],"results":[168],"suggest":[169],"protein":[173],"particular":[181],"physiological":[183],"function":[184],"VIP/VIP":[186],"terminating":[189],"extensive":[191],"I":[197],"IV.":[199]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}