{"id":"https://openalex.org/W67397018","doi":null,"title":"Swimming Exercise Ameliorates Elevated Blood Pressure and Vascular Endothelial Dysfunction in Old Rats","display_name":"Swimming Exercise Ameliorates Elevated Blood Pressure and Vascular Endothelial Dysfunction in Old Rats","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W67397018","mag":"67397018"},"language":"en","primary_location":{"id":"mag:67397018","doi":null,"is_oa":true,"landing_page_url":"http://article.sapub.org/10.5923.j.ajmms.20140405.10.html","pdf_url":null,"source":{"id":"https://openalex.org/S2764498450","display_name":"American Journal of Medicine and Medical Sciences","issn_l":"2165-901X","issn":["2165-901X","2165-9036"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Medicine and Medical Sciences","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://article.sapub.org/10.5923.j.ajmms.20140405.10.html","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035375149","display_name":"Nermin Rezk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nermin Rezk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045249402","display_name":"Safaa El-Kotb","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Safaa El-Kotb","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5011348833","display_name":"Yahya M. Naguib","orcid":"https://orcid.org/0000-0001-5851-7238","observed_orcids":["https://orcid.org/0000-0001-5851-7238"]},"institutions":[{"id":"https://openalex.org/I63601056","display_name":"Menoufia University","ror":"https://ror.org/05sjrb944","country_code":"EG","type":"education","lineage":["https://openalex.org/I63601056"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Yahya M. Naguib","raw_affiliation_strings":["[Menoufia University]"],"raw_orcid":"https://orcid.org/0000-0001-5851-7238","affiliations":[{"raw_affiliation_string":"[Menoufia University]","institution_ids":["https://openalex.org/I63601056"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.00551512,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"4","issue":"5","first_page":"192","last_page":"202"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9121000170707703,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9121000170707703,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.07400000095367432,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/swimming-training","display_name":"swimming training","score":0.996999979019165},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.7580000162124634},{"id":"https://openalex.org/keywords/systolic-hypertension","display_name":"systolic hypertension","score":0.8989999890327454},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.9660000205039978},{"id":"https://openalex.org/keywords/vascular-function","display_name":"vascular function","score":0.5440000295639038},{"id":"https://openalex.org/keywords/sympathetic-nervous-system","display_name":"sympathetic nervous system","score":0.8899999856948853},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.9520000219345093},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9290000200271606},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.8539999723434448},{"id":"https://openalex.org/keywords/antioxidant-capacity","display_name":"antioxidant capacity","score":0.8429999947547913},{"id":"https://openalex.org/keywords/renal-artery-blood-flow","display_name":"renal artery blood flow","score":0.8870000243186951},{"id":"https://openalex.org/keywords/renal-vascular-resistance","display_name":"renal vascular resistance","score":0.6639999747276306}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.919247567653656},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7283182740211487},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7159833908081055},{"id":"https://openalex.org/C2780972559","wikidata":"https://www.wikidata.org/wiki/Q550061","display_name":"Endothelial dysfunction","level":2,"score":0.6818664073944092},{"id":"https://openalex.org/C2779961880","wikidata":"https://www.wikidata.org/wiki/Q1067506","display_name":"Vasoconstriction","level":2,"score":0.6686248183250427},{"id":"https://openalex.org/C2778096610","wikidata":"https://www.wikidata.org/wiki/Q1476525","display_name":"Dyslipidemia","level":3,"score":0.615045428276062},{"id":"https://openalex.org/C2776533406","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic nervous system","level":3,"score":0.5777771472930908},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5686394572257996},{"id":"https://openalex.org/C120770815","wikidata":"https://www.wikidata.org/wiki/Q14859627","display_name":"Vasodilation","level":2,"score":0.5436659455299377},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.46465224027633667},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.36435359716415405},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.12523996829986572}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:67397018","doi":null,"is_oa":true,"landing_page_url":"http://article.sapub.org/10.5923.j.ajmms.20140405.10.html","pdf_url":null,"source":{"id":"https://openalex.org/S2764498450","display_name":"American Journal of Medicine and Medical Sciences","issn_l":"2165-901X","issn":["2165-901X","2165-9036"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Medicine and Medical Sciences","raw_type":null}],"best_oa_location":{"id":"mag:67397018","doi":null,"is_oa":true,"landing_page_url":"http://article.sapub.org/10.5923.j.ajmms.20140405.10.html","pdf_url":null,"source":{"id":"https://openalex.org/S2764498450","display_name":"American Journal of Medicine and Medical Sciences","issn_l":"2165-901X","issn":["2165-901X","2165-9036"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Medicine and Medical Sciences","raw_type":null},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W1550849850","https://openalex.org/W1559904992","https://openalex.org/W1577665082","https://openalex.org/W1593169702","https://openalex.org/W1769035943","https://openalex.org/W1963783377","https://openalex.org/W1966355383","https://openalex.org/W1969140956","https://openalex.org/W1973542881","https://openalex.org/W1977956145","https://openalex.org/W1979098009","https://openalex.org/W1993498121","https://openalex.org/W1999330035","https://openalex.org/W2002879009","https://openalex.org/W2005457113","https://openalex.org/W2010227433","https://openalex.org/W2012766272","https://openalex.org/W2014775570","https://openalex.org/W2017845353","https://openalex.org/W2025128457","https://openalex.org/W2030883271","https://openalex.org/W2031273906","https://openalex.org/W2032790009","https://openalex.org/W2038651315","https://openalex.org/W2050062329","https://openalex.org/W2050856345","https://openalex.org/W2052628744","https://openalex.org/W2053097473","https://openalex.org/W2063427558","https://openalex.org/W2067410380","https://openalex.org/W2077064503","https://openalex.org/W2079728347","https://openalex.org/W2083396130","https://openalex.org/W2095304299","https://openalex.org/W2101088082","https://openalex.org/W2104721620","https://openalex.org/W2104842795","https://openalex.org/W2119545067","https://openalex.org/W2121930919","https://openalex.org/W2122875885","https://openalex.org/W2124149023","https://openalex.org/W2126284874","https://openalex.org/W2128088826","https://openalex.org/W2130400487","https://openalex.org/W2130827864","https://openalex.org/W2133706890","https://openalex.org/W2136740341","https://openalex.org/W2137737171","https://openalex.org/W2138475885","https://openalex.org/W2140281925","https://openalex.org/W2148172817","https://openalex.org/W2148637873","https://openalex.org/W2152317863","https://openalex.org/W2152407864","https://openalex.org/W2153273912","https://openalex.org/W2154736130","https://openalex.org/W2156612696","https://openalex.org/W2163261367","https://openalex.org/W2164979547","https://openalex.org/W2165201727","https://openalex.org/W2166665077","https://openalex.org/W2166729907","https://openalex.org/W2170389508","https://openalex.org/W2171915168","https://openalex.org/W2395534953","https://openalex.org/W2400729719","https://openalex.org/W2519068143","https://openalex.org/W3015544325"],"related_works":["https://openalex.org/W2035162889","https://openalex.org/W4200044622","https://openalex.org/W2999735234","https://openalex.org/W2895828587","https://openalex.org/W3089051693","https://openalex.org/W2016512523","https://openalex.org/W2060049825","https://openalex.org/W2363513262","https://openalex.org/W2958839703","https://openalex.org/W4394958724"],"abstract_inverted_index":{"Background":[0],"and":[1,17,40,67,86,97,123,143,225],"Aim:":[2],"Advancing":[3],"age":[4],"increases":[5],"the":[6,21,52],"risk":[7],"of":[8,15,35,82],"cardiovascular":[9],"diseases,":[10],"resulting":[11],"in":[12,51,115,174],"higher":[13,106],"rates":[14],"morbidity":[16],"mortality.":[18],"We":[19,215],"tested":[20],"hypothesis":[22],"that":[23,218],"habitual":[24,219],"swimming":[25,72,220],"exercise":[26,150],"would":[27],"reverse":[28],"age-related":[29],"systolic":[30,223],"hypertension,":[31],"vascular":[32],"dysfunction,":[33],"hyperactivity":[34],"sympathetic":[36,83,132,154],"nervous":[37,84],"system,":[38,85],"dyslipidemia,":[39,135],"oxidative":[41],"stress.":[42],"Methods:":[43],"Thirty":[44],"male":[45],"Wistar":[46],"albino":[47],"rats":[48,177],"were":[49,56,91,100,208],"used":[50],"present":[53],"study.":[54],"Rats":[55],"divided":[57],"(10/group)":[58],"into":[59],"young":[60,121,166],"(3-4":[61],"months),":[62,66],"old":[63,68,116,175,203],"sedentary":[64,117,204],"(22-24":[65],"exercised":[69,176],"(6":[70],"weeks":[71],"protocol)":[73],"rats.":[74,167,205],"Systolic":[75],"blood":[76,139],"pressure":[77],"(SBP),":[78],"endothelial":[79,226],"function,":[80],"sensitivity":[81],"renal":[87,95,137,145],"artery":[88,138,146],"Doppler":[89],"flowmetry":[90],"evaluated.":[92],"Serum":[93],"lipids,":[94,158],"biomarkers":[96],"oxidant-antioxidant":[98],"status":[99],"assessed.":[101],"Results:":[102],"SBP":[103],"was":[104,124,190],"significantly":[105,170],"(100":[107],"\u00b1":[108,112,179,183,193,197],"4.83":[109],"vs":[110],"80":[111],"3.34":[113],"mmHg)":[114],"when":[118,200],"compared":[119,201],"to":[120,161,165,202],"rats,":[122],"associated":[125],"with":[126],"reduced":[127,136],"endothelial-dependent":[128],"dilation":[129],"(EDD),":[130],"increased":[131,144,169],"adrenergic":[133,155],"vasoconstriction,":[134,156],"flow":[140],"velocity":[141],"(RBFV),":[142],"resistance":[147],"(RAR).":[148],"Swimming":[149,168],"restored":[151],"SBP,":[152],"EDD,":[153],"serum":[157,188],"RBFV,":[159],"RAR,":[160],"levels":[162],"almost":[163],"comparable":[164],"total":[171],"antioxidant":[172],"capacity":[173],"(2.37":[178],"0.33":[180],"vs.":[181,195],"1.92":[182],"0.44":[184],"mM":[185],"/L),":[186],"while":[187],"malondialdhyde":[189],"decreased":[191],"(2.58":[192],"0.23":[194],"4.42":[196],"0.14":[198],"\u03b7M/L),":[199],"All":[206],"results":[207],"statistically":[209],"significant":[210],"(p":[211],"<":[212],"0.05).":[213],"Conclusion:":[214],"report":[216],"here":[217],"ameliorates":[221],"age-dependent":[222],"hypertension":[224],"dysfunction":[227],"possibly":[228],"by":[229],"anti-oxidant":[230],"mechanism.":[231]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}