{"id":"https://openalex.org/W66337786","doi":"https://doi.org/10.1007/4-431-28775-2_4","title":"The Role of the Blood-Brain Barrier in Feeding: Leptin","display_name":"The Role of the Blood-Brain Barrier in Feeding: Leptin","publication_year":2007,"publication_date":"2007-02-24","ids":{"openalex":"https://openalex.org/W66337786","doi":"https://doi.org/10.1007/4-431-28775-2_4","mag":"66337786"},"language":"en","primary_location":{"id":"doi:10.1007/4-431-28775-2_4","doi":"https://doi.org/10.1007/4-431-28775-2_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/4-431-28775-2_4","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breathing, Feeding, and Neuroprotection","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2496547261","display_name":"Breathing, Feeding, and Neuroprotection"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054959155","display_name":"William A. Banks","orcid":"https://orcid.org/0000-0002-0496-3619","observed_orcids":["https://orcid.org/0000-0002-0496-3619"]},"institutions":[{"id":"https://openalex.org/I4210104016","display_name":"St. Louis VA Medical Center","ror":"https://ror.org/014c68a74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210104016","https://openalex.org/I4210150881","https://openalex.org/I4210165236"]},{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William A. Banks","raw_affiliation_strings":["Division of Geriatrics, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, USA","Geriatric Research, Educational, and Clinical Center, Veterans Affairs Medical Center, St. Louis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Geriatrics, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, USA","institution_ids":["https://openalex.org/I47838141"]},{"raw_affiliation_string":"Geriatric Research, Educational, and Clinical Center, Veterans Affairs Medical Center, St. Louis, USA","institution_ids":["https://openalex.org/I4210104016"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037000230","display_name":"Susan A. Farr","orcid":"https://orcid.org/0000-0002-0481-2570","observed_orcids":["https://orcid.org/0000-0002-0481-2570"]},"institutions":[{"id":"https://openalex.org/I4210104016","display_name":"St. Louis VA Medical Center","ror":"https://ror.org/014c68a74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210104016","https://openalex.org/I4210150881","https://openalex.org/I4210165236"]},{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan A. Farr","raw_affiliation_strings":["Division of Geriatrics, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, USA","Geriatric Research, Educational, and Clinical Center, Veterans Affairs Medical Center, St. Louis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Geriatrics, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, USA","institution_ids":["https://openalex.org/I47838141"]},{"raw_affiliation_string":"Geriatric Research, Educational, and Clinical Center, Veterans Affairs Medical Center, St. Louis, USA","institution_ids":["https://openalex.org/I4210104016"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102748794","display_name":"John Edward Morley","orcid":"https://orcid.org/0000-0003-1104-0393","observed_orcids":["https://orcid.org/0000-0003-1104-0393"]},"institutions":[{"id":"https://openalex.org/I4210104016","display_name":"St. Louis VA Medical Center","ror":"https://ror.org/014c68a74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210104016","https://openalex.org/I4210150881","https://openalex.org/I4210165236"]},{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John E. Morley","raw_affiliation_strings":["Division of Geriatrics, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, USA","Geriatric Research, Educational, and Clinical Center, Veterans Affairs Medical Center, St. Louis, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Geriatrics, Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, USA","institution_ids":["https://openalex.org/I47838141"]},{"raw_affiliation_string":"Geriatric Research, Educational, and Clinical Center, Veterans Affairs Medical Center, St. Louis, USA","institution_ids":["https://openalex.org/I4210104016"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.03064067,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"27","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9282000064849854,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":0.9282000064849854,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.05909999832510948,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":1.0},{"id":"https://openalex.org/keywords/leptin","display_name":"leptin","score":0.9810000061988831},{"id":"https://openalex.org/keywords/leptin-resistance","display_name":"leptin resistance","score":0.8759999871253967},{"id":"https://openalex.org/keywords/leptin-transport","display_name":"leptin transport","score":0.7519999742507935},{"id":"https://openalex.org/keywords/food-intake-regulation","display_name":"food intake regulation","score":0.6340000033378601},{"id":"https://openalex.org/keywords/alpha1-adrenergic-receptors","display_name":"alpha1-adrenoceptors","score":0.8730000257492065},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9819999933242798},{"id":"https://openalex.org/keywords/cerebrospinal-fluid","display_name":"cerebrospinal fluid","score":0.859000027179718},{"id":"https://openalex.org/keywords/brain-interstitial-fluid","display_name":"brain interstitial fluid","score":0.6779999732971191},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.4230000078678131},{"id":"https://openalex.org/keywords/starvation","display_name":"starvation","score":0.5820000171661377},{"id":"https://openalex.org/keywords/hypertriglyceridemia","display_name":"hypertriglyceridemia","score":0.8410000205039978}],"concepts":[{"id":"https://openalex.org/C2780613262","wikidata":"https://www.wikidata.org/wiki/Q223739","display_name":"Leptin","level":3,"score":0.9488639831542969},{"id":"https://openalex.org/C2778402981","wikidata":"https://www.wikidata.org/wiki/Q221694","display_name":"Blood\u2013brain barrier","level":3,"score":0.7037737369537354},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.6116083264350891},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5983806848526001},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5963851809501648},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5887089967727661},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.4945528209209442},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.47789156436920166},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.45329421758651733},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3912985026836395},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.39082908630371094}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/4-431-28775-2_4","doi":"https://doi.org/10.1007/4-431-28775-2_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/4-431-28775-2_4","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Breathing, Feeding, and Neuroprotection","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W295145141","https://openalex.org/W609865038","https://openalex.org/W653446446","https://openalex.org/W1631449371","https://openalex.org/W1803448096","https://openalex.org/W1966608496","https://openalex.org/W1967923917","https://openalex.org/W1974760551","https://openalex.org/W1982009292","https://openalex.org/W1983812459","https://openalex.org/W1992328870","https://openalex.org/W1993099930","https://openalex.org/W1996713062","https://openalex.org/W2005290625","https://openalex.org/W2015781261","https://openalex.org/W2043458888","https://openalex.org/W2054072494","https://openalex.org/W2059711459","https://openalex.org/W2061340727","https://openalex.org/W2065310133","https://openalex.org/W2066295481","https://openalex.org/W2075187033","https://openalex.org/W2111732109","https://openalex.org/W2144373418","https://openalex.org/W2170271954","https://openalex.org/W2183797541","https://openalex.org/W2188022238","https://openalex.org/W2288113889","https://openalex.org/W4241572710"],"related_works":["https://openalex.org/W2056460191","https://openalex.org/W1585391215","https://openalex.org/W1994316085","https://openalex.org/W94825638","https://openalex.org/W2024807787","https://openalex.org/W1973360608","https://openalex.org/W2086139024","https://openalex.org/W2109251309","https://openalex.org/W1534057962","https://openalex.org/W4409140366"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}
