{"id":"https://openalex.org/W6599883","doi":"https://doi.org/10.1016/j.molcatb.2004.01.012","title":"Microbial models of animal drug metabolism","display_name":"Microbial models of animal drug metabolism","publication_year":2004,"publication_date":"2004-04-14","ids":{"openalex":"https://openalex.org/W6599883","doi":"https://doi.org/10.1016/j.molcatb.2004.01.012","mag":"6599883"},"language":"en","primary_location":{"id":"doi:10.1016/j.molcatb.2004.01.012","doi":"https://doi.org/10.1016/j.molcatb.2004.01.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molcatb.2004.01.012","pdf_url":null,"source":{"id":"https://openalex.org/S21009921","display_name":"Journal of Molecular Catalysis B Enzymatic","issn_l":"1381-1177","issn":["1381-1177","1873-3158"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Catalysis B: Enzymatic","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066810872","display_name":"Vanessa Alexandre","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117082","display_name":"Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques","ror":"https://ror.org/028qedy27","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210117082","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Vanessa Alexandre","raw_affiliation_strings":["Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601, Universit\u00e9 Ren\u00e9 Descartes-Paris V, 45 Rue des Saints-P\u00e8res, 75006 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601, Universit\u00e9 Ren\u00e9 Descartes-Paris V, 45 Rue des Saints-P\u00e8res, 75006 Paris, France","institution_ids":["https://openalex.org/I4210117082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090062918","display_name":"Sophie Ladril","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117082","display_name":"Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques","ror":"https://ror.org/028qedy27","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210117082","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Sophie Ladril","raw_affiliation_strings":["Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601, Universit\u00e9 Ren\u00e9 Descartes-Paris V, 45 Rue des Saints-P\u00e8res, 75006 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601, Universit\u00e9 Ren\u00e9 Descartes-Paris V, 45 Rue des Saints-P\u00e8res, 75006 Paris, France","institution_ids":["https://openalex.org/I4210117082"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016570543","display_name":"Mich\u00e8le Maurs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117082","display_name":"Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques","ror":"https://ror.org/028qedy27","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210117082","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mich\u00e8le Maurs","raw_affiliation_strings":["Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601, Universit\u00e9 Ren\u00e9 Descartes-Paris V, 45 Rue des Saints-P\u00e8res, 75006 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601, Universit\u00e9 Ren\u00e9 Descartes-Paris V, 45 Rue des Saints-P\u00e8res, 75006 Paris, France","institution_ids":["https://openalex.org/I4210117082"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038999397","display_name":"Robert G. Azerad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210117082","display_name":"Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques","ror":"https://ror.org/028qedy27","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I4210117082","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Robert Azerad","raw_affiliation_strings":["Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601, Universit\u00e9 Ren\u00e9 Descartes-Paris V, 45 Rue des Saints-P\u00e8res, 75006 Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, UMR 8601, Universit\u00e9 Ren\u00e9 Descartes-Paris V, 45 Rue des Saints-P\u00e8res, 75006 Paris, France","institution_ids":["https://openalex.org/I4210117082"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5038999397"],"corresponding_institution_ids":["https://openalex.org/I4210117082"],"apc_list":null,"apc_paid":null,"fwci":0.3537,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.54610195,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"29","issue":"1-6","first_page":"173","last_page":"179"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.29490000009536743,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.29490000009536743,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.2797999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.14480000734329224,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/irbesartan","display_name":"irbesartan","score":0.9879999756813049},{"id":"https://openalex.org/keywords/microbial-transformation","display_name":"microbial transformation","score":0.7059999704360962},{"id":"https://openalex.org/keywords/streptomyces","display_name":"Streptomyces","score":0.9480000138282776},{"id":"https://openalex.org/keywords/fungal-strain","display_name":"fungal strain","score":0.6620000004768372},{"id":"https://openalex.org/keywords/antihypertensive-drugs","display_name":"antihypertensive drugs","score":0.8809999823570251},{"id":"https://openalex.org/keywords/stereochemistry","display_name":"stereochemistry","score":0.4410000145435333}],"concepts":[{"id":"https://openalex.org/C175605896","wikidata":"https://www.wikidata.org/wiki/Q39833","display_name":"Microorganism","level":3,"score":0.7163209319114685},{"id":"https://openalex.org/C138716334","wikidata":"https://www.wikidata.org/wiki/Q268477","display_name":"Diastereomer","level":2,"score":0.5830544829368591},{"id":"https://openalex.org/C150487720","wikidata":"https://www.wikidata.org/wiki/Q422553","display_name":"Glycosidic bond","level":3,"score":0.5588254928588867},{"id":"https://openalex.org/C2779920670","wikidata":"https://www.wikidata.org/wiki/Q1144013","display_name":"Streptomyces","level":3,"score":0.511947512626648},{"id":"https://openalex.org/C101014631","wikidata":"https://www.wikidata.org/wiki/Q4889568","display_name":"Microbial metabolism","level":3,"score":0.5018651485443115},{"id":"https://openalex.org/C2780259554","wikidata":"https://www.wikidata.org/wiki/Q947266","display_name":"Irbesartan","level":3,"score":0.4745895564556122},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47174251079559326},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.45772987604141235},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.41754817962646484},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.408125638961792},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3609183132648468},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3422009348869324},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09330812096595764},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.08291995525360107},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.molcatb.2004.01.012","doi":"https://doi.org/10.1016/j.molcatb.2004.01.012","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molcatb.2004.01.012","pdf_url":null,"source":{"id":"https://openalex.org/S21009921","display_name":"Journal of Molecular Catalysis B Enzymatic","issn_l":"1381-1177","issn":["1381-1177","1873-3158"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Catalysis B: Enzymatic","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W1543348686","https://openalex.org/W1974073287","https://openalex.org/W1979425525","https://openalex.org/W2063412050","https://openalex.org/W2112501422","https://openalex.org/W2152852886","https://openalex.org/W2243023482","https://openalex.org/W2291762828","https://openalex.org/W2331376208","https://openalex.org/W2336891920","https://openalex.org/W2409143950","https://openalex.org/W2435937398"],"related_works":["https://openalex.org/W2331376208","https://openalex.org/W7120813064","https://openalex.org/W2053603039","https://openalex.org/W992595841","https://openalex.org/W2409143950","https://openalex.org/W2243023482","https://openalex.org/W1981383781","https://openalex.org/W2248202918","https://openalex.org/W7096007107","https://openalex.org/W2257810199"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}