{"id":"https://openalex.org/W658304198","doi":null,"title":"Blood urea nitrogen, middle molecules and uremic morbidity in hemodialyzed patients","display_name":"Blood urea nitrogen, middle molecules and uremic morbidity in hemodialyzed patients","publication_year":1986,"publication_date":"1986-01-01","ids":{"openalex":"https://openalex.org/W658304198","mag":"658304198"},"language":"en","primary_location":{"id":"pmh:oai:dipot.ulb.ac.be:2013/15093","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/15093","pdf_url":null,"source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Dialysis & Transplantation, 15","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113457672","display_name":"Jean\u2010Louis Vanherweghem","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jean\u2010Louis Vanherweghem","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111384655","display_name":"Pierre-Alain Gevenois","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Pierre-Alain Gevenois","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020639835","display_name":"Michel Dhaene","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michel Dhaene","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048334327","display_name":"J. C. Stolaer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. C. Stolaer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016249576","display_name":"Michel Goldman","orcid":"https://orcid.org/0000-0003-0222-7287","observed_orcids":["https://orcid.org/0000-0003-0222-7287"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michel Goldman","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0222-7287","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023923871","display_name":"Claude Thayse","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Claude Thayse","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5112142567","display_name":"Charles Toussaint","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Toussaint","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4265,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.57454037,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"2","first_page":"86","last_page":"91"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10641","display_name":"Central Venous Catheters and Hemodialysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.7319999933242798},{"id":"https://openalex.org/keywords/dialysis-adequacy","display_name":"dialysis adequacy","score":0.8029999732971191},{"id":"https://openalex.org/keywords/middle-molecule-clearance","display_name":"middle molecule clearance","score":0.8360000252723694},{"id":"https://openalex.org/keywords/blood-urea-nitrogen","display_name":"blood urea nitrogen","score":0.9480000138282776},{"id":"https://openalex.org/keywords/transfusion-requirements","display_name":"transfusion requirements","score":0.6290000081062317},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.8100000023841858},{"id":"https://openalex.org/keywords/underdialysis","display_name":"underdialysis","score":0.718999981880188},{"id":"https://openalex.org/keywords/motor-nerve-conduction-velocity","display_name":"motor nerve conduction velocity","score":0.8220000267028809},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.6539999842643738}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9308172464370728},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.8074935674667358},{"id":"https://openalex.org/C2778176769","wikidata":"https://www.wikidata.org/wiki/Q764079","display_name":"Blood urea nitrogen","level":3,"score":0.7950969934463501},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.5908684134483337},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.552043080329895},{"id":"https://openalex.org/C2781001862","wikidata":"https://www.wikidata.org/wiki/Q501561","display_name":"Pericarditis","level":2,"score":0.5400915741920471},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.4962058663368225},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4883434474468231},{"id":"https://openalex.org/C2776635150","wikidata":"https://www.wikidata.org/wiki/Q13365776","display_name":"Uremia","level":2,"score":0.44962722063064575},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.43933433294296265},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.43557441234588623},{"id":"https://openalex.org/C138944611","wikidata":"https://www.wikidata.org/wiki/Q1163287","display_name":"Clearance","level":2,"score":0.41533833742141724},{"id":"https://openalex.org/C2776399438","wikidata":"https://www.wikidata.org/wiki/Q5270637","display_name":"Dialysis adequacy","level":3,"score":0.4151343107223511},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.30247238278388977}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:dipot.ulb.ac.be:2013/15093","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/15093","pdf_url":null,"source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Dialysis & Transplantation, 15","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:658304198","doi":null,"is_oa":false,"landing_page_url":"https://difusion.ulb.ac.be/vufind/Record/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/15093/Details","pdf_url":null,"source":{"id":"https://openalex.org/S149820601","display_name":"Dialysis & Transplantation","issn_l":"0090-2934","issn":["0090-2934","1932-6920"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Dialysis & Transplantation","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W747420361","https://openalex.org/W362573822","https://openalex.org/W2009730157","https://openalex.org/W587148223","https://openalex.org/W104006342","https://openalex.org/W4282938682","https://openalex.org/W2015850213","https://openalex.org/W2444366303","https://openalex.org/W1971960815","https://openalex.org/W2464981999"],"abstract_inverted_index":{"The":[0,163],"adequacy":[1],"of":[2,41,75,81,148,158,181,194,275],"dialysis":[3,68],"remains":[4],"debatable.":[5],"We":[6],"compared":[7,93,120],"the":[8,23,42,45,66,82,87,201,260,270],"morbidity":[9,229,255],"in":[10,86,153,207,262],"our":[11,252],"hemodialyzed":[12],"patients":[13,94,106,121,132,149,159,208],"according":[14],"to":[15,27,77,105,131],"predialysis":[16],"blood":[17,189],"urea":[18],"nitrogen":[19],"(BUN)":[20],"levels,":[21,184,267],"on":[22,44],"one":[24],"hand,":[25],"and":[26],"calculated":[28],"middle":[29],"molecule":[30],"clearance":[31,36,40],"(MMC":[32],"=":[33,97,103,109,115,124,129,135,141],"residual":[34,54],"creatinine":[35,55,168],"+":[37],"vitamin":[38],"B12":[39],"dialyzer),":[43],"other":[46],"hand.":[47],"Patients":[48],"with":[49,53,95,107,122,133,209,226,241,259,265],"systemic":[50],"diseases":[51],"or":[52],"clearances":[56],"above":[57],"3":[58],"ml/min":[59],"were":[60,70,84,166],"excluded.":[61],"Fifty-one":[62],"patient,":[63],"incorporated":[64],"into":[65],"same":[67],"schedule,":[69],"studied":[71],"during":[72],"a":[73],"follow-up":[74],"six":[76],"30":[78],"months.":[79],"Analyses":[80],"data":[83],"conducted":[85],"following":[88,164],"two":[89],"ways:":[90],"Analysis":[91],"A":[92],"BUN":[96,108,211,266],"115":[98],"\u00b1":[99,111,126,137],"12":[100],"mg/dl":[101,113],"(n":[102,114,128],"26)":[104,130],"85":[110],"9":[112],"25),":[116],"while":[117],"analysis":[118,144,154],"B":[119],"MMC":[123,134,223,263],"37":[125],"8":[127],"16":[136],"5":[138],"(1/week;":[139],"n":[140],"25).":[142],"In":[143,251],"A,":[145],"both":[146,156],"groups":[147,157],"had":[150,160],"comparable":[151],"MMC;":[152],"B,":[155],"similar":[161,220],"BUN.":[162],"parameters":[165],"recorded:":[167],"clearance,":[169],"age,":[170],"sex,":[171],"weight,":[172],"mortalities,":[173],"hepatitis,":[174],"pericarditis,":[175],"bacterial":[176],"infection,":[177],"gastrointestinal":[178],"diseases,":[179],"duration":[180],"hospitalization,":[182],"iPTH":[183],"motor":[185,276],"nerve":[186,277],"conduction":[187,278],"velocity,":[188],"pressure,":[190],"hematologic":[191],"values,":[192],"number":[193],"transfusions.":[195,273],"Among":[196],"all":[197],"these":[198],"parameters,":[199],"only":[200],"need":[202,271],"for":[203,219,269,272,284],"transfusions":[204],"was":[205,224,256],"higher":[206,210,228],"(24.8":[212],"v":[213,231,245],"14.4":[214],"units/patient/year,":[215],"P":[216,235,248],"<":[217,236,249],".001)":[218],"hematocrit.":[221],"Lower":[222],"associated":[225],"significantly":[227],"(2.12":[230],"1.33":[232],"recorded":[233],"complications/patient/year,":[234],".05),":[237],"as":[238,240],"well":[239],"longer":[242],"hospitalization":[243],"(15.5":[244],"5.3":[246],"days/patient/year,":[247],".001).":[250],"experience,":[253],"overall":[254],"better":[257],"correlated":[258],"loss":[261],"than":[264],"except":[268],"Monitoring":[274],"velocity":[279],"did":[280],"not":[281],"seem":[282],"useful":[283],"detecting":[285],"underdialysis.":[286]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}