{"id":"https://openalex.org/W65822152","doi":null,"title":"Subgingival microflora and antibody responses against periodontal bacteria of young Japanese patients with type 1 diabetes mellitus.","display_name":"Subgingival microflora and antibody responses against periodontal bacteria of young Japanese patients with type 1 diabetes mellitus.","publication_year":2001,"publication_date":"2001-10-01","ids":{"openalex":"https://openalex.org/W65822152","mag":"65822152","pmid":"https://pubmed.ncbi.nlm.nih.gov/12666949"},"language":"en","primary_location":{"id":"pmid:12666949","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12666949","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the International Academy of Periodontology","raw_type":"Comparative Study"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040650539","display_name":"Keiso Takahashi","orcid":"https://orcid.org/0000-0002-4051-2452","observed_orcids":["https://orcid.org/0000-0002-4051-2452"]},"institutions":[{"id":"https://openalex.org/I163770644","display_name":"Okayama University","ror":"https://ror.org/02pc6pc55","country_code":"JP","type":"education","lineage":["https://openalex.org/I163770644"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"K Takahashi","raw_affiliation_strings":["Department of Periodontology and Endodontology, Okayama University Dental School, 2-5-1 Shikata-cho, Okayama 700-8525, Japan","Okayama University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontology and Endodontology, Okayama University Dental School, 2-5-1 Shikata-cho, Okayama 700-8525, Japan","institution_ids":["https://openalex.org/I163770644"]},{"raw_affiliation_string":"Okayama University","institution_ids":["https://openalex.org/I163770644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103212354","display_name":"Fusanori Nishimura","orcid":"https://orcid.org/0000-0003-1572-2180","observed_orcids":["https://orcid.org/0000-0003-1572-2180"]},"institutions":[{"id":"https://openalex.org/I163770644","display_name":"Okayama University","ror":"https://ror.org/02pc6pc55","country_code":"JP","type":"education","lineage":["https://openalex.org/I163770644"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"F Nishimura","raw_affiliation_strings":["Okayama University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Okayama University","institution_ids":["https://openalex.org/I163770644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112716018","display_name":"Masaki Kurihara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I163770644","display_name":"Okayama University","ror":"https://ror.org/02pc6pc55","country_code":"JP","type":"education","lineage":["https://openalex.org/I163770644"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M Kurihara","raw_affiliation_strings":["Okayama University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Okayama University","institution_ids":["https://openalex.org/I163770644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044050049","display_name":"Yoshihiro Iwamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I163770644","display_name":"Okayama University","ror":"https://ror.org/02pc6pc55","country_code":"JP","type":"education","lineage":["https://openalex.org/I163770644"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y Iwamoto","raw_affiliation_strings":["Okayama University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Okayama University","institution_ids":["https://openalex.org/I163770644"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049686289","display_name":"Shogo Takashiba","orcid":"https://orcid.org/0000-0002-4712-6829","observed_orcids":["https://orcid.org/0000-0002-4712-6829"]},"institutions":[{"id":"https://openalex.org/I163770644","display_name":"Okayama University","ror":"https://ror.org/02pc6pc55","country_code":"JP","type":"education","lineage":["https://openalex.org/I163770644"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"S Takashiba","raw_affiliation_strings":["Okayama University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Okayama University","institution_ids":["https://openalex.org/I163770644"]}]},{"author_position":"middle","author":{"id":null,"display_name":"T Miyata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I163770644","display_name":"Okayama University","ror":"https://ror.org/02pc6pc55","country_code":"JP","type":"education","lineage":["https://openalex.org/I163770644"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T Miyata","raw_affiliation_strings":["Okayama University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Okayama University","institution_ids":["https://openalex.org/I163770644"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111537713","display_name":"Y. Murayama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I163770644","display_name":"Okayama University","ror":"https://ror.org/02pc6pc55","country_code":"JP","type":"education","lineage":["https://openalex.org/I163770644"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y Murayama","raw_affiliation_strings":["Okayama University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Okayama University","institution_ids":["https://openalex.org/I163770644"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I163770644"],"apc_list":null,"apc_paid":null,"fwci":0.88,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.72503618,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"3","issue":"4","first_page":"104","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10257","display_name":"Oral microbiology and periodontitis research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3506","display_name":"Periodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13768","display_name":"Oral and gingival health research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3611","display_name":"Pharmacy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12439","display_name":"Dental Research and COVID-19","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9950000047683716},{"id":"https://openalex.org/keywords/periodontal-disease","display_name":"periodontal disease","score":0.9440000057220459},{"id":"https://openalex.org/keywords/periodontitis","display_name":"periodontitis","score":0.8659999966621399},{"id":"https://openalex.org/keywords/gingivitis","display_name":"gingivitis","score":0.9200000166893005},{"id":"https://openalex.org/keywords/subgingival-plaque","display_name":"subgingival plaque","score":0.6809999942779541},{"id":"https://openalex.org/keywords/periodontal-pathogens","display_name":"periodontal pathogens","score":0.8220000267028809},{"id":"https://openalex.org/keywords/porphyromonas-gingivalis","display_name":"Porphyromonas gingivalis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/porphyromonas-intermedia","display_name":"Porphyromonas intermedia","score":0.8980000019073486},{"id":"https://openalex.org/keywords/aggregatibacter-actinomycetemcomitans","display_name":"Aggregatibacter actinomycetemcomitans","score":0.9890000224113464},{"id":"https://openalex.org/keywords/capnocytophaga-ochracea","display_name":"Capnocytophaga ochracea","score":0.996999979019165},{"id":"https://openalex.org/keywords/serum-igg","display_name":"serum IgG","score":0.8080000281333923},{"id":"https://openalex.org/keywords/diabetes-duration","display_name":"diabetes duration","score":0.718999981880188},{"id":"https://openalex.org/keywords/japanese-patients","display_name":"Japanese patients","score":0.3630000054836273}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.869708776473999},{"id":"https://openalex.org/C2776895894","wikidata":"https://www.wikidata.org/wiki/Q2022791","display_name":"Prevotella intermedia","level":4,"score":0.828477144241333},{"id":"https://openalex.org/C2780791200","wikidata":"https://www.wikidata.org/wiki/Q673083","display_name":"Gingivitis","level":2,"score":0.805579662322998},{"id":"https://openalex.org/C2780183776","wikidata":"https://www.wikidata.org/wiki/Q3214147","display_name":"Porphyromonas gingivalis","level":3,"score":0.6930827498435974},{"id":"https://openalex.org/C2780385504","wikidata":"https://www.wikidata.org/wiki/Q520127","display_name":"Periodontitis","level":2,"score":0.692071795463562},{"id":"https://openalex.org/C2780728835","wikidata":"https://www.wikidata.org/wiki/Q310714","display_name":"Actinobacillus","level":3,"score":0.6620402336120605},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.5604575276374817},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5311554670333862},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4945513904094696},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4434337913990021},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3573848605155945},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.3494553565979004},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.12368011474609375}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002206","descriptor_name":"Capnocytophaga","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D002206","descriptor_name":"Capnocytophaga","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D003773","descriptor_name":"Dental Plaque","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005891","descriptor_name":"Gingivitis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005891","descriptor_name":"Gingivitis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006090","descriptor_name":"Gram-Negative Bacteria","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":true},{"descriptor_ui":"D006090","descriptor_name":"Gram-Negative Bacteria","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010510","descriptor_name":"Periodontal Diseases","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010510","descriptor_name":"Periodontal Diseases","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010518","descriptor_name":"Periodontitis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D010519","descriptor_name":"Periodontium","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D010519","descriptor_name":"Periodontium","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012329","descriptor_name":"RNA, Bacterial","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016009","descriptor_name":"Chi-Square Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016966","descriptor_name":"Porphyromonas gingivalis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016966","descriptor_name":"Porphyromonas gingivalis","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D016976","descriptor_name":"Aggregatibacter actinomycetemcomitans","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016976","descriptor_name":"Aggregatibacter actinomycetemcomitans","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018713","descriptor_name":"Prevotella intermedia","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018713","descriptor_name":"Prevotella intermedia","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:12666949","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12666949","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the International Academy of Periodontology","raw_type":"Comparative Study"},{"id":"mag:65822152","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12666949","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2082776571","https://openalex.org/W61939313","https://openalex.org/W2013666597","https://openalex.org/W1980028051","https://openalex.org/W2951262851","https://openalex.org/W4404057962","https://openalex.org/W2102001108","https://openalex.org/W2006182928","https://openalex.org/W7128381774","https://openalex.org/W2606543902"],"abstract_inverted_index":{"Periodontal":[0],"disease":[1,217],"is":[2],"a":[3,159,167,212],"complication":[4],"of":[5,24,35,164,170,225,233],"patients":[6,236],"with":[7,198,237],"type":[8,52],"1":[9,53],"diabetes":[10,165],"mellitus":[11],"(T1DM),":[12],"although":[13],"the":[14,33,137,152,155,179,194,231],"mechanisms":[15],"responsible":[16],"for":[17,105,215,230],"this":[18,25,77],"relationship":[19],"remain":[20],"unclear.":[21],"The":[22],"aim":[23],"study":[26],"was":[27],"to":[28],"examine":[29],"oral":[30],"manifestations":[31],"and":[32,42,58,99,115,166,175,200,218,223],"prevalence":[34],"periodontal":[36,107,134,216],"pathogens":[37],"from":[38],"subgingival":[39],"plaque":[40],"samples":[41],"serum":[43],"IgG":[44,129,184],"antibody":[45,130,185],"levels":[46,131,186],"against":[47,132,187],"them":[48],"in":[49,76,193,235],"young":[50],"Japanese":[51,60,208],"diabetic":[54],"subjects.":[55],"One":[56],"hundred":[57],"seventeen":[59],"T1DM":[61,87,153,209,226],"subjects":[62,88,171,210],"(53":[63],"male,":[64],"64":[65],"female,":[66],"mean":[67,162],"age":[68],"+/-":[69,72],"SD,":[70],"16":[71],"6.5":[73],"years)":[74],"participated":[75],"study.":[78],"Thirty-nine":[79],"periodontally":[80,101],"healthy,":[81],"age-matched":[82],"nondiabetics":[83],"served":[84],"as":[85],"controls.":[86],"were":[89,118,145,190],"clinically":[90],"assigned":[91],"into":[92],"three":[93],"groups:":[94],"12":[95,133],"periodontitis,":[96],"32":[97],"gingivitis":[98],"73":[100],"healthy.":[102],"Microbiological":[103],"tests":[104],"four":[106,138],"pathogens,":[108],"Porphyromonas":[109],"gingivalis,":[110],"Actinobacillus":[111],"actinomycetemcomitans,":[112],"Prevotella":[113],"intermedia":[114,177],"Capnocytophaga":[116],"ochracea":[117],"performed":[119],"using":[120],"16S":[121],"ribosomal":[122],"RNA-based":[123],"polymerase":[124,142],"chain":[125,143],"reaction":[126,144],"methods.":[127],"Serum":[128,183],"bacteria":[135],"including":[136],"species":[139],"assessed":[140],"by":[141,147],"measured":[146],"enzyme-linked":[148],"immunosorbent":[149],"assay.":[150],"In":[151],"subjects,":[154],"Periodontitis":[156,195],"group":[157,196,214],"had":[158],"significantly":[160,191],"longer":[161],"duration":[163,224],"higher":[168],"percentages":[169],"harbouring":[172],"P.":[173,176,188,220],"gingivalis":[174,189,221],"than":[178],"Periodontally":[180,201],"Healthy":[181,202],"group.":[182],"elevated":[192],"compared":[197],"Gingivitis":[199],"groups.":[203],"These":[204],"results":[205],"indicate":[206],"that":[207],"are":[211,227],"high-risk":[213],"both":[219],"infection":[222],"risk":[228],"factors":[229],"progression":[232],"periodontitis":[234],"T1DM.":[238]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}