{"id":"https://openalex.org/W656779167","doi":"https://doi.org/10.1097/md.0000000000000933","title":"The Effectiveness and Safety of Acupuncture for Patients With Alzheimer Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","display_name":"The Effectiveness and Safety of Acupuncture for Patients With Alzheimer Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","publication_year":2015,"publication_date":"2015-06-01","ids":{"openalex":"https://openalex.org/W656779167","doi":"https://doi.org/10.1097/md.0000000000000933","mag":"656779167","pmid":"https://pubmed.ncbi.nlm.nih.gov/26039131","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4616366"},"language":"en","primary_location":{"id":"doi:10.1097/md.0000000000000933","doi":"https://doi.org/10.1097/md.0000000000000933","is_oa":true,"landing_page_url":"https://doi.org/10.1097/md.0000000000000933","pdf_url":null,"source":{"id":"https://openalex.org/S28966261","display_name":"Medicine","issn_l":"0025-7974","issn":["0025-7974","1536-5964"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1097/md.0000000000000933","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100615655","display_name":"Jing Wen Zhou","orcid":"https://orcid.org/0000-0001-8336-7278","observed_orcids":["https://orcid.org/0000-0001-8336-7278"]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210094218","display_name":"Xuan Wu Hospital of the Capital Medical University","ror":"https://ror.org/00k7r7f88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210094218"]},{"id":"https://openalex.org/I4210141683","display_name":"China Academy of Chinese Medical Sciences","ror":"https://ror.org/042pgcv68","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210141683"]},{"id":"https://openalex.org/I4210146387","display_name":"Guang\u2019anmen Hospital","ror":"https://ror.org/04gjmb875","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146387"]},{"id":"https://openalex.org/I4405261377","display_name":"China National Knowledge Infrastructure (China)","ror":"https://ror.org/05761st14","country_code":"CN","type":"company","lineage":["https://openalex.org/I4405261377"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Zhou","raw_affiliation_strings":["From the Department of Acupuncture (JZ, WP, WL, ZL), Guang'anmen Hospital, China Academy of Chinese Medical Sciences; Beijing University of Chinese Medicine (JZ, WL); and Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","Abbreviations: AD = Alzheimer disease, ADAS-cog = Alzheimer's Disease Assessment Scale-Cognition, ADL = ability of daily living, CBM = Chinese Biomedicine Literature, CENTRAL = Central Register of Controlled Trials, CI = confidence intervals, CMCC = Chinese Medical Current Content, CNKI = China National Knowledge Infrastructure, DSM = Diagnostic and Statistical Manual of Mental Disorders, FAQ = functional activities questionnaire, FDA = Food and Drug Administration, HDS = Hasegawa's Dementia Scale, HDS-R = Revised Hasegawa's Dementia Scale, ICD = International Classification of Diseases, ITT = intention-to-treat, MCID = mean minimum clinically important difference, MD = mean differences, MMSE = Mini Mental State Examination, MoCA = Montreal cognitive assessment, MRI = magnetic resonance imaging, NIA-AA = Aging and the Alzheimer's Association workgroup, NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association, OCDAD = Operational Criteria for the Diagnosis of Alzheimer's Disease, RCTs = Randomized controlled trials, SMD = standardized mean differences, WMD = weighted mean differences","Beijing University of Chinese Medicine (JZ, WL)","Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","Ethical approval was not needed as the data used in this systematic review was not individual patient data and there were no privacy issues to address. The results will be disseminated by publication of the manuscript in a peer reviewed journal, or presentation at a relevant conference","From the Department of Acupuncture (JZ, WP, WL, ZL), Guang\u2019anmen Hospital, China Academy of Chinese Medical Sciences","Jing Zhou and Zhishun Liu contributed to the conception of the study. The manuscript of the review was drafted by Jing Zhou, and was revised by Weina Peng. The search strategy was developed by all authors and run by Wang Li and Jing Zhou, who also independently screened the potential studies, extracted data from included studies, assessed the risk of bias, and finished the data synthesis. Zhishun Liu and Min Xu arbitrated disagreements and ensured that no errors occurred during the study. All authors approved the publication of the review","This is an open access article distributed under the Creative Commons Attribution-NonCommercial License, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Acupuncture (JZ, WP, WL, ZL), Guang'anmen Hospital, China Academy of Chinese Medical Sciences; Beijing University of Chinese Medicine (JZ, WL); and Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I17747738","https://openalex.org/I183519381","https://openalex.org/I4210094218","https://openalex.org/I4210141683","https://openalex.org/I4210146387"]},{"raw_affiliation_string":"Abbreviations: AD = Alzheimer disease, ADAS-cog = Alzheimer's Disease Assessment Scale-Cognition, ADL = ability of daily living, CBM = Chinese Biomedicine Literature, CENTRAL = Central Register of Controlled Trials, CI = confidence intervals, CMCC = Chinese Medical Current Content, CNKI = China National Knowledge Infrastructure, DSM = Diagnostic and Statistical Manual of Mental Disorders, FAQ = functional activities questionnaire, FDA = Food and Drug Administration, HDS = Hasegawa's Dementia Scale, HDS-R = Revised Hasegawa's Dementia Scale, ICD = International Classification of Diseases, ITT = intention-to-treat, MCID = mean minimum clinically important difference, MD = mean differences, MMSE = Mini Mental State Examination, MoCA = Montreal cognitive assessment, MRI = magnetic resonance imaging, NIA-AA = Aging and the Alzheimer's Association workgroup, NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association, OCDAD = Operational Criteria for the Diagnosis of Alzheimer's Disease, RCTs = Randomized controlled trials, SMD = standardized mean differences, WMD = weighted mean differences","institution_ids":["https://openalex.org/I4405261377"]},{"raw_affiliation_string":"Beijing University of Chinese Medicine (JZ, WL)","institution_ids":["https://openalex.org/I17747738"]},{"raw_affiliation_string":"Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210094218"]},{"raw_affiliation_string":"Ethical approval was not needed as the data used in this systematic review was not individual patient data and there were no privacy issues to address. The results will be disseminated by publication of the manuscript in a peer reviewed journal, or presentation at a relevant conference","institution_ids":[]},{"raw_affiliation_string":"From the Department of Acupuncture (JZ, WP, WL, ZL), Guang\u2019anmen Hospital, China Academy of Chinese Medical Sciences","institution_ids":["https://openalex.org/I4210141683","https://openalex.org/I4210146387"]},{"raw_affiliation_string":"Jing Zhou and Zhishun Liu contributed to the conception of the study. The manuscript of the review was drafted by Jing Zhou, and was revised by Weina Peng. The search strategy was developed by all authors and run by Wang Li and Jing Zhou, who also independently screened the potential studies, extracted data from included studies, assessed the risk of bias, and finished the data synthesis. Zhishun Liu and Min Xu arbitrated disagreements and ensured that no errors occurred during the study. All authors approved the publication of the review","institution_ids":[]},{"raw_affiliation_string":"This is an open access article distributed under the Creative Commons Attribution-NonCommercial License, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001569730","display_name":"Weina Peng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210094218","display_name":"Xuan Wu Hospital of the Capital Medical University","ror":"https://ror.org/00k7r7f88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210094218"]},{"id":"https://openalex.org/I4210141683","display_name":"China Academy of Chinese Medical Sciences","ror":"https://ror.org/042pgcv68","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210141683"]},{"id":"https://openalex.org/I4210146387","display_name":"Guang\u2019anmen Hospital","ror":"https://ror.org/04gjmb875","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146387"]},{"id":"https://openalex.org/I4405261377","display_name":"China National Knowledge Infrastructure (China)","ror":"https://ror.org/05761st14","country_code":"CN","type":"company","lineage":["https://openalex.org/I4405261377"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weina Peng","raw_affiliation_strings":["Beijing University of Chinese Medicine (JZ, WL)","From the Department of Acupuncture (JZ, WP, WL, ZL), Guang\u2019anmen Hospital, China Academy of Chinese Medical Sciences","and Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","Abbreviations: AD = Alzheimer disease, ADAS-cog = Alzheimer's Disease Assessment Scale-Cognition, ADL = ability of daily living, CBM = Chinese Biomedicine Literature, CENTRAL = Central Register of Controlled Trials, CI = confidence intervals, CMCC = Chinese Medical Current Content, CNKI = China National Knowledge Infrastructure, DSM = Diagnostic and Statistical Manual of Mental Disorders, FAQ = functional activities questionnaire, FDA = Food and Drug Administration, HDS = Hasegawa's Dementia Scale, HDS-R = Revised Hasegawa's Dementia Scale, ICD = International Classification of Diseases, ITT = intention-to-treat, MCID = mean minimum clinically important difference, MD = mean differences, MMSE = Mini Mental State Examination, MoCA = Montreal cognitive assessment, MRI = magnetic resonance imaging, NIA-AA = Aging and the Alzheimer's Association workgroup, NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association, OCDAD = Operational Criteria for the Diagnosis of Alzheimer's Disease, RCTs = Randomized controlled trials, SMD = standardized mean differences, WMD = weighted mean differences","Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","Ethical approval was not needed as the data used in this systematic review was not individual patient data and there were no privacy issues to address. The results will be disseminated by publication of the manuscript in a peer reviewed journal, or presentation at a relevant conference","Jing Zhou and Zhishun Liu contributed to the conception of the study. The manuscript of the review was drafted by Jing Zhou, and was revised by Weina Peng. The search strategy was developed by all authors and run by Wang Li and Jing Zhou, who also independently screened the potential studies, extracted data from included studies, assessed the risk of bias, and finished the data synthesis. Zhishun Liu and Min Xu arbitrated disagreements and ensured that no errors occurred during the study. All authors approved the publication of the review","This is an open access article distributed under the Creative Commons Attribution-NonCommercial License, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing University of Chinese Medicine (JZ, WL)","institution_ids":["https://openalex.org/I17747738"]},{"raw_affiliation_string":"From the Department of Acupuncture (JZ, WP, WL, ZL), Guang\u2019anmen Hospital, China Academy of Chinese Medical Sciences","institution_ids":["https://openalex.org/I4210141683","https://openalex.org/I4210146387"]},{"raw_affiliation_string":"and Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210094218"]},{"raw_affiliation_string":"Abbreviations: AD = Alzheimer disease, ADAS-cog = Alzheimer's Disease Assessment Scale-Cognition, ADL = ability of daily living, CBM = Chinese Biomedicine Literature, CENTRAL = Central Register of Controlled Trials, CI = confidence intervals, CMCC = Chinese Medical Current Content, CNKI = China National Knowledge Infrastructure, DSM = Diagnostic and Statistical Manual of Mental Disorders, FAQ = functional activities questionnaire, FDA = Food and Drug Administration, HDS = Hasegawa's Dementia Scale, HDS-R = Revised Hasegawa's Dementia Scale, ICD = International Classification of Diseases, ITT = intention-to-treat, MCID = mean minimum clinically important difference, MD = mean differences, MMSE = Mini Mental State Examination, MoCA = Montreal cognitive assessment, MRI = magnetic resonance imaging, NIA-AA = Aging and the Alzheimer's Association workgroup, NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association, OCDAD = Operational Criteria for the Diagnosis of Alzheimer's Disease, RCTs = Randomized controlled trials, SMD = standardized mean differences, WMD = weighted mean differences","institution_ids":["https://openalex.org/I4405261377"]},{"raw_affiliation_string":"Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210094218"]},{"raw_affiliation_string":"Ethical approval was not needed as the data used in this systematic review was not individual patient data and there were no privacy issues to address. The results will be disseminated by publication of the manuscript in a peer reviewed journal, or presentation at a relevant conference","institution_ids":[]},{"raw_affiliation_string":"Jing Zhou and Zhishun Liu contributed to the conception of the study. The manuscript of the review was drafted by Jing Zhou, and was revised by Weina Peng. The search strategy was developed by all authors and run by Wang Li and Jing Zhou, who also independently screened the potential studies, extracted data from included studies, assessed the risk of bias, and finished the data synthesis. Zhishun Liu and Min Xu arbitrated disagreements and ensured that no errors occurred during the study. All authors approved the publication of the review","institution_ids":[]},{"raw_affiliation_string":"This is an open access article distributed under the Creative Commons Attribution-NonCommercial License, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102016565","display_name":"Min Xu","orcid":"https://orcid.org/0000-0003-3226-8223","observed_orcids":["https://orcid.org/0000-0003-3226-8223"]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210094218","display_name":"Xuan Wu Hospital of the Capital Medical University","ror":"https://ror.org/00k7r7f88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210094218"]},{"id":"https://openalex.org/I4210141683","display_name":"China Academy of Chinese Medical Sciences","ror":"https://ror.org/042pgcv68","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210141683"]},{"id":"https://openalex.org/I4210146387","display_name":"Guang\u2019anmen Hospital","ror":"https://ror.org/04gjmb875","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146387"]},{"id":"https://openalex.org/I4405261377","display_name":"China National Knowledge Infrastructure (China)","ror":"https://ror.org/05761st14","country_code":"CN","type":"company","lineage":["https://openalex.org/I4405261377"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Xu","raw_affiliation_strings":["Beijing University of Chinese Medicine (JZ, WL)","From the Department of Acupuncture (JZ, WP, WL, ZL), Guang\u2019anmen Hospital, China Academy of Chinese Medical Sciences","and Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","Abbreviations: AD = Alzheimer disease, ADAS-cog = Alzheimer's Disease Assessment Scale-Cognition, ADL = ability of daily living, CBM = Chinese Biomedicine Literature, CENTRAL = Central Register of Controlled Trials, CI = confidence intervals, CMCC = Chinese Medical Current Content, CNKI = China National Knowledge Infrastructure, DSM = Diagnostic and Statistical Manual of Mental Disorders, FAQ = functional activities questionnaire, FDA = Food and Drug Administration, HDS = Hasegawa's Dementia Scale, HDS-R = Revised Hasegawa's Dementia Scale, ICD = International Classification of Diseases, ITT = intention-to-treat, MCID = mean minimum clinically important difference, MD = mean differences, MMSE = Mini Mental State Examination, MoCA = Montreal cognitive assessment, MRI = magnetic resonance imaging, NIA-AA = Aging and the Alzheimer's Association workgroup, NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association, OCDAD = Operational Criteria for the Diagnosis of Alzheimer's Disease, RCTs = Randomized controlled trials, SMD = standardized mean differences, WMD = weighted mean differences","Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","Ethical approval was not needed as the data used in this systematic review was not individual patient data and there were no privacy issues to address. The results will be disseminated by publication of the manuscript in a peer reviewed journal, or presentation at a relevant conference","Jing Zhou and Zhishun Liu contributed to the conception of the study. The manuscript of the review was drafted by Jing Zhou, and was revised by Weina Peng. The search strategy was developed by all authors and run by Wang Li and Jing Zhou, who also independently screened the potential studies, extracted data from included studies, assessed the risk of bias, and finished the data synthesis. Zhishun Liu and Min Xu arbitrated disagreements and ensured that no errors occurred during the study. All authors approved the publication of the review","This is an open access article distributed under the Creative Commons Attribution-NonCommercial License, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing University of Chinese Medicine (JZ, WL)","institution_ids":["https://openalex.org/I17747738"]},{"raw_affiliation_string":"From the Department of Acupuncture (JZ, WP, WL, ZL), Guang\u2019anmen Hospital, China Academy of Chinese Medical Sciences","institution_ids":["https://openalex.org/I4210141683","https://openalex.org/I4210146387"]},{"raw_affiliation_string":"and Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210094218"]},{"raw_affiliation_string":"Abbreviations: AD = Alzheimer disease, ADAS-cog = Alzheimer's Disease Assessment Scale-Cognition, ADL = ability of daily living, CBM = Chinese Biomedicine Literature, CENTRAL = Central Register of Controlled Trials, CI = confidence intervals, CMCC = Chinese Medical Current Content, CNKI = China National Knowledge Infrastructure, DSM = Diagnostic and Statistical Manual of Mental Disorders, FAQ = functional activities questionnaire, FDA = Food and Drug Administration, HDS = Hasegawa's Dementia Scale, HDS-R = Revised Hasegawa's Dementia Scale, ICD = International Classification of Diseases, ITT = intention-to-treat, MCID = mean minimum clinically important difference, MD = mean differences, MMSE = Mini Mental State Examination, MoCA = Montreal cognitive assessment, MRI = magnetic resonance imaging, NIA-AA = Aging and the Alzheimer's Association workgroup, NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association, OCDAD = Operational Criteria for the Diagnosis of Alzheimer's Disease, RCTs = Randomized controlled trials, SMD = standardized mean differences, WMD = weighted mean differences","institution_ids":["https://openalex.org/I4405261377"]},{"raw_affiliation_string":"Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210094218"]},{"raw_affiliation_string":"Ethical approval was not needed as the data used in this systematic review was not individual patient data and there were no privacy issues to address. The results will be disseminated by publication of the manuscript in a peer reviewed journal, or presentation at a relevant conference","institution_ids":[]},{"raw_affiliation_string":"Jing Zhou and Zhishun Liu contributed to the conception of the study. The manuscript of the review was drafted by Jing Zhou, and was revised by Weina Peng. The search strategy was developed by all authors and run by Wang Li and Jing Zhou, who also independently screened the potential studies, extracted data from included studies, assessed the risk of bias, and finished the data synthesis. Zhishun Liu and Min Xu arbitrated disagreements and ensured that no errors occurred during the study. All authors approved the publication of the review","institution_ids":[]},{"raw_affiliation_string":"This is an open access article distributed under the Creative Commons Attribution-NonCommercial License, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100382447","display_name":"Wang Li","orcid":"https://orcid.org/0009-0004-6476-8630","observed_orcids":["https://orcid.org/0009-0004-6476-8630"]},"institutions":[{"id":"https://openalex.org/I17747738","display_name":"Beijing University of Chinese Medicine","ror":"https://ror.org/05damtm70","country_code":"CN","type":"education","lineage":["https://openalex.org/I17747738"]},{"id":"https://openalex.org/I183519381","display_name":"Capital Medical University","ror":"https://ror.org/013xs5b60","country_code":"CN","type":"education","lineage":["https://openalex.org/I183519381"]},{"id":"https://openalex.org/I4210094218","display_name":"Xuan Wu Hospital of the Capital Medical University","ror":"https://ror.org/00k7r7f88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210094218"]},{"id":"https://openalex.org/I4210141683","display_name":"China Academy of Chinese Medical Sciences","ror":"https://ror.org/042pgcv68","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210141683"]},{"id":"https://openalex.org/I4210146387","display_name":"Guang\u2019anmen Hospital","ror":"https://ror.org/04gjmb875","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146387"]},{"id":"https://openalex.org/I4405261377","display_name":"China National Knowledge Infrastructure (China)","ror":"https://ror.org/05761st14","country_code":"CN","type":"company","lineage":["https://openalex.org/I4405261377"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wang Li","raw_affiliation_strings":["Beijing University of Chinese Medicine (JZ, WL)","From the Department of Acupuncture (JZ, WP, WL, ZL), Guang\u2019anmen Hospital, China Academy of Chinese Medical Sciences","and Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","Abbreviations: AD = Alzheimer disease, ADAS-cog = Alzheimer's Disease Assessment Scale-Cognition, ADL = ability of daily living, CBM = Chinese Biomedicine Literature, CENTRAL = Central Register of Controlled Trials, CI = confidence intervals, CMCC = Chinese Medical Current Content, CNKI = China National Knowledge Infrastructure, DSM = Diagnostic and Statistical Manual of Mental Disorders, FAQ = functional activities questionnaire, FDA = Food and Drug Administration, HDS = Hasegawa's Dementia Scale, HDS-R = Revised Hasegawa's Dementia Scale, ICD = International Classification of Diseases, ITT = intention-to-treat, MCID = mean minimum clinically important difference, MD = mean differences, MMSE = Mini Mental State Examination, MoCA = Montreal cognitive assessment, MRI = magnetic resonance imaging, NIA-AA = Aging and the Alzheimer's Association workgroup, NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association, OCDAD = Operational Criteria for the Diagnosis of Alzheimer's Disease, RCTs = Randomized controlled trials, SMD = standardized mean differences, WMD = weighted mean differences","Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","Ethical approval was not needed as the data used in this systematic review was not individual patient data and there were no privacy issues to address. The results will be disseminated by publication of the manuscript in a peer reviewed journal, or presentation at a relevant conference","Jing Zhou and Zhishun Liu contributed to the conception of the study. The manuscript of the review was drafted by Jing Zhou, and was revised by Weina Peng. The search strategy was developed by all authors and run by Wang Li and Jing Zhou, who also independently screened the potential studies, extracted data from included studies, assessed the risk of bias, and finished the data synthesis. Zhishun Liu and Min Xu arbitrated disagreements and ensured that no errors occurred during the study. All authors approved the publication of the review","This is an open access article distributed under the Creative Commons Attribution-NonCommercial License, where it is permissible to download, share and reproduce the work in any medium, provided it is properly cited. The work cannot be used commercially. http://creativecommons.org/licenses/by-nc/4.0"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Beijing University of Chinese Medicine (JZ, WL)","institution_ids":["https://openalex.org/I17747738"]},{"raw_affiliation_string":"From the Department of Acupuncture (JZ, WP, WL, ZL), Guang\u2019anmen Hospital, China Academy of Chinese Medical Sciences","institution_ids":["https://openalex.org/I4210141683","https://openalex.org/I4210146387"]},{"raw_affiliation_string":"and Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210094218"]},{"raw_affiliation_string":"Abbreviations: AD = Alzheimer disease, ADAS-cog = Alzheimer's Disease Assessment Scale-Cognition, ADL = ability of daily living, CBM = Chinese Biomedicine Literature, CENTRAL = Central Register of Controlled Trials, CI = confidence intervals, CMCC = Chinese Medical Current Content, CNKI = China National Knowledge Infrastructure, DSM = Diagnostic and Statistical Manual of Mental Disorders, FAQ = functional activities questionnaire, FDA = Food and Drug Administration, HDS = Hasegawa's Dementia Scale, HDS-R = Revised Hasegawa's Dementia Scale, ICD = International Classification of Diseases, ITT = intention-to-treat, MCID = mean minimum clinically important difference, MD = mean differences, MMSE = Mini Mental State Examination, MoCA = Montreal cognitive assessment, MRI = magnetic resonance imaging, NIA-AA = Aging and the Alzheimer's Association workgroup, NINCDS-ADRDA = National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association, OCDAD = Operational Criteria for the Diagnosis of Alzheimer's Disease, RCTs = Randomized controlled trials, SMD = standardized mean differences, WMD = weighted mean differences","institution_ids":["https://openalex.org/I4405261377"]},{"raw_affiliation_string":"Department of Neurology (MX), Xuan Wu Hospital, Capital Medical University, Beijing, China","institution_ids":["https://openalex.org/I183519381","https://openalex.org/I4210094218"]},{"raw_affiliation_string":"Ethical approval was not needed as the data used in this systematic review was not individual patient data and there were no privacy issues to address. 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