{"id":"https://openalex.org/W64163403","doi":"https://doi.org/10.1007/978-3-642-77633-5_8","title":"BCR/ABL Enhances Growth of Multipotent Progenitor Cells But Does Not Block Their Differentiation Potential In Vitro","display_name":"BCR/ABL Enhances Growth of Multipotent Progenitor Cells But Does Not Block Their Differentiation Potential In Vitro","publication_year":1992,"publication_date":"1992-01-01","ids":{"openalex":"https://openalex.org/W64163403","doi":"https://doi.org/10.1007/978-3-642-77633-5_8","mag":"64163403","pmid":"https://pubmed.ncbi.nlm.nih.gov/1490392"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-77633-5_8","doi":"https://doi.org/10.1007/978-3-642-77633-5_8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-77633-5_8","pdf_url":null,"source":{"id":"https://openalex.org/S192937065","display_name":"Current topics in microbiology and immunology","issn_l":"0070-217X","issn":["0070-217X","2196-9965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Microbiology and Immunology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2917759401","display_name":"Mechanisms in B-Cell Neoplasia 1992"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016422415","display_name":"Mikhail L. Gishizky","orcid":"https://orcid.org/0000-0002-2704-9790","observed_orcids":["https://orcid.org/0000-0002-2704-9790"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I2803209242","display_name":"University of California System","ror":"https://ror.org/00pjdza24","country_code":"US","type":"education","lineage":["https://openalex.org/I2803209242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. L. Gishizky","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of California, Los Angeles 90024","University of California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of California, Los Angeles 90024","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"University of California","institution_ids":["https://openalex.org/I2803209242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087708211","display_name":"Owen N. Witte","orcid":"https://orcid.org/0000-0003-4461-4533","observed_orcids":["https://orcid.org/0000-0003-4461-4533"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I2803209242","display_name":"University of California System","ror":"https://ror.org/00pjdza24","country_code":"US","type":"education","lineage":["https://openalex.org/I2803209242"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"O. N. Witte","raw_affiliation_strings":["Department of Microbiology and Molecular Genetics, University of California, Los Angeles, USA","Howard Hughes Medical Institute, University of California, Los Angeles, USA","Howard Hughes Medical Institute, University of California","University of California"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Molecular Genetics, University of California, Los Angeles, USA","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, University of California, Los Angeles, USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I161318765"]},{"raw_affiliation_string":"Howard Hughes Medical Institute, University of California","institution_ids":["https://openalex.org/I1344073410"]},{"raw_affiliation_string":"University of California","institution_ids":["https://openalex.org/I2803209242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1736,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.7054409,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"182","issue":null,"first_page":"65","last_page":"72"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11215","display_name":"Chronic Myeloid Leukemia Treatments","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11215","display_name":"Chronic Myeloid Leukemia Treatments","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11559","display_name":"Retinoids in leukemia and cellular processes","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bcr-abl","display_name":"BCR-ABL","score":0.9639999866485596},{"id":"https://openalex.org/keywords/p210-bcr-abl","display_name":"p210 BCR-ABL","score":0.8799999952316284},{"id":"https://openalex.org/keywords/multipotent-progenitors","display_name":"multipotent progenitors","score":0.9950000047683716},{"id":"https://openalex.org/keywords/hematopoietic-differentiation","display_name":"hematopoietic differentiation","score":0.7580000162124634},{"id":"https://openalex.org/keywords/interleukin-3","display_name":"interleukin-3","score":0.6639999747276306},{"id":"https://openalex.org/keywords/mast-cell-differentiation","display_name":"mast cell differentiation","score":0.6330000162124634},{"id":"https://openalex.org/keywords/macrophage-differentiation","display_name":"macrophage differentiation","score":0.9779999852180481},{"id":"https://openalex.org/keywords/granulocytic-differentiation","display_name":"granulocytic differentiation","score":0.9380000233650208},{"id":"https://openalex.org/keywords/immunoglobulin-heavy-chain-gene-rearrangement","display_name":"immunoglobulin heavy chain gene rearrangement","score":0.8679999709129333},{"id":"https://openalex.org/keywords/leukemogenesis","display_name":"leukemogenesis","score":0.7730000019073486},{"id":"https://openalex.org/keywords/hematopoietic-development","display_name":"hematopoietic development","score":0.7870000004768372},{"id":"https://openalex.org/keywords/cell-transformation","display_name":"cell transformation","score":0.4309999942779541}],"concepts":[{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.6873644590377808},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6138859391212463},{"id":"https://openalex.org/C2910776680","wikidata":"https://www.wikidata.org/wiki/Q862600","display_name":"Multipotent Stem Cell","level":4,"score":0.56276935338974},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5076800584793091},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3820343017578125},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.337177574634552},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33712831139564514},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.31712859869003296},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06203547120094299}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002471","descriptor_name":"Cell Transformation, Neoplastic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006412","descriptor_name":"Hematopoietic Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009857","descriptor_name":"Oncogenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-3-642-77633-5_8","doi":"https://doi.org/10.1007/978-3-642-77633-5_8","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-77633-5_8","pdf_url":null,"source":{"id":"https://openalex.org/S192937065","display_name":"Current topics in microbiology and immunology","issn_l":"0070-217X","issn":["0070-217X","2196-9965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Microbiology and Immunology","raw_type":"book-chapter"},{"id":"pmid:1490392","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1490392","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current topics in microbiology and immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W129878118","https://openalex.org/W1951381722","https://openalex.org/W2006518962","https://openalex.org/W2065563953","https://openalex.org/W2076372887","https://openalex.org/W2171593969","https://openalex.org/W2339475636"],"related_works":["https://openalex.org/W2171593969","https://openalex.org/W4241507999","https://openalex.org/W2317775706","https://openalex.org/W251289427","https://openalex.org/W2062919433","https://openalex.org/W2083935574","https://openalex.org/W2078336183","https://openalex.org/W2149395094","https://openalex.org/W1772305653","https://openalex.org/W2021270704"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}