{"id":"https://openalex.org/W640904583","doi":null,"title":"The Impact of Medical Management on Quality of Life in Brugada Syndrome Patients","display_name":"The Impact of Medical Management on Quality of Life in Brugada Syndrome Patients","publication_year":2012,"publication_date":"2012-06-29","ids":{"openalex":"https://openalex.org/W640904583","mag":"640904583"},"language":"en","primary_location":{"id":"pmh:oai:d-scholarship.pitt.edu:11687","doi":null,"is_oa":false,"landing_page_url":"https://d-scholarship.pitt.edu/11687/1/RichardsSK_2012.pdf","pdf_url":"https://d-scholarship.pitt.edu/11687/1/RichardsSK_2012.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079994058","display_name":"Sarah Richards","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sarah Richards","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5079994058"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9247999787330627,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9247999787330627,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.058800000697374344,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11083","display_name":"Cardiac Health and Mental Health","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brugada-syndrome","display_name":"Brugada syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9850000143051147},{"id":"https://openalex.org/keywords/implantable-cardioverter-defibrillator","display_name":"implantable cardioverter-defibrillator","score":0.9950000047683716},{"id":"https://openalex.org/keywords/familial-mutation","display_name":"familial mutation","score":0.4399999976158142},{"id":"https://openalex.org/keywords/sudden-cardiac-death","display_name":"sudden cardiac death","score":0.7429999709129333},{"id":"https://openalex.org/keywords/inherited-arrhythmia-syndromes","display_name":"inherited arrhythmia","score":0.8510000109672546},{"id":"https://openalex.org/keywords/psychosocial-impact","display_name":"psychosocial impact","score":0.7400000095367432},{"id":"https://openalex.org/keywords/sf-36v2","display_name":"SF-36v2","score":0.7710000276565552},{"id":"https://openalex.org/keywords/multigenerational-families","display_name":"multigenerational families","score":0.6740000247955322},{"id":"https://openalex.org/keywords/asymptomatic-patients","display_name":"asymptomatic patients","score":0.578000009059906},{"id":"https://openalex.org/keywords/genetic-diagnosis","display_name":"genetic diagnosis","score":0.7459999918937683},{"id":"https://openalex.org/keywords/syncope","display_name":"syncope","score":0.5720000267028809},{"id":"https://openalex.org/keywords/patient-reported-outcomes","display_name":"patient-reported outcomes","score":0.46700000762939453}],"concepts":[{"id":"https://openalex.org/C2777382798","wikidata":"https://www.wikidata.org/wiki/Q599683","display_name":"Brugada syndrome","level":2,"score":0.9522333145141602},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8372498750686646},{"id":"https://openalex.org/C2775935837","wikidata":"https://www.wikidata.org/wiki/Q202837","display_name":"Sudden cardiac death","level":2,"score":0.7457889318466187},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.608262300491333},{"id":"https://openalex.org/C2777093960","wikidata":"https://www.wikidata.org/wiki/Q594446","display_name":"Implantable cardioverter-defibrillator","level":2,"score":0.5897188782691956},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5289261937141418},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3921731412410736},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3783363997936249},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.08006933331489563},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:d-scholarship.pitt.edu:11687","doi":null,"is_oa":false,"landing_page_url":"https://d-scholarship.pitt.edu/11687/1/RichardsSK_2012.pdf","pdf_url":"https://d-scholarship.pitt.edu/11687/1/RichardsSK_2012.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},{"id":"mag:640904583","doi":null,"is_oa":false,"landing_page_url":"http://d-scholarship.pitt.edu/11687/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W15456981","https://openalex.org/W175920791","https://openalex.org/W651032991","https://openalex.org/W1491803208","https://openalex.org/W1932037221","https://openalex.org/W1967523306","https://openalex.org/W1980361970","https://openalex.org/W1984314206","https://openalex.org/W1989195099","https://openalex.org/W1995634785","https://openalex.org/W1997096095","https://openalex.org/W2008527258","https://openalex.org/W2008898851","https://openalex.org/W2010200876","https://openalex.org/W2020926399","https://openalex.org/W2021095297","https://openalex.org/W2023329185","https://openalex.org/W2023689636","https://openalex.org/W2037377025","https://openalex.org/W2039301510","https://openalex.org/W2054106258","https://openalex.org/W2066498094","https://openalex.org/W2094037852","https://openalex.org/W2095569622","https://openalex.org/W2101633048","https://openalex.org/W2101731509","https://openalex.org/W2116058578","https://openalex.org/W2122455147","https://openalex.org/W2128734390","https://openalex.org/W2140332009","https://openalex.org/W2142021012","https://openalex.org/W2142022288","https://openalex.org/W2142125868","https://openalex.org/W2142441092","https://openalex.org/W2146036381","https://openalex.org/W2146214743","https://openalex.org/W2149671207","https://openalex.org/W2150145251","https://openalex.org/W2155121555","https://openalex.org/W2165850575","https://openalex.org/W2187238462"],"related_works":["https://openalex.org/W2146036381","https://openalex.org/W4391190639","https://openalex.org/W7223146274","https://openalex.org/W2807941667","https://openalex.org/W4391785484","https://openalex.org/W7020866868","https://openalex.org/W2325594757","https://openalex.org/W2187238462","https://openalex.org/W2885267345","https://openalex.org/W2763945992"],"abstract_inverted_index":{"PURPOSE:":[0],"Brugada":[1,70,97,150,222,332,398],"syndrome":[2,71,98,151,399],"is":[3,38,106,125,392,403],"an":[4,18,39,52,112,199,225,231,249,298,307,342,375],"inherited":[5],"cardiac":[6,31,48],"arrhythmia":[7],"disorder":[8],"characterized":[9],"by":[10],"ST":[11],"segment":[12],"elevation":[13],"in":[14,84,136,158,195,213,240,269,327,349],"leads":[15],"V1-V3":[16],"on":[17,66,72,224],"electrocardiogram":[19],"(ECG).":[20],"The":[21,88,118,244,368],"main":[22,245],"symptoms":[23],"of":[24,58,69,75,81,90,101,122,130,133,184,189,202,206,217,257,271,351,384,411],"this":[25,85,91,123,412],"condition":[26],"are":[27,322,335],"syncope":[28],"and":[29,103,114,233,259,279,290,356,365,373],"sudden":[30],"death.":[32],"Medical":[33],"management":[34,83,135,169,380],"for":[35,247,262],"symptomatic":[36,291],"patients":[37,49],"implantable":[40],"cardioverter":[41],"defibrillator":[42],"(ICD).":[43],"Research":[44],"has":[45,155],"shown":[46],"that":[47,331,378],"who":[50],"have":[51,63],"ICD":[53,113,232,250,299,308,320,376],"experience":[54],"a":[55,137,146,153,255,301,359,393],"decreased":[56],"quality":[57,74,100,183,270,350,383],"life.":[59,185],"However,":[60],"limited":[61],"studies":[62],"been":[64,156],"done":[65],"the":[67,79,128,131,159,172,196,207,210,221,238,241,276,294,408],"impact":[68,80,382],"patient":[73,86,139,339,413],"life":[76,102,272,352],"let":[77],"alone":[78],"medical":[82,134,168,379],"population.":[87,140,414],"purpose":[89],"study":[92,197],"was":[93,164,179,236,266,283,345],"to":[94,126,166,181,193,254,324,337,389,397,405],"understand":[95],"how":[96],"affects":[99],"if":[104],"there":[105,391],"any":[107],"difference":[108,268,286,348,369],"between":[109,273,288,353,370],"those":[110,115,274,280,305,325,354,357,363,371],"with":[111,149,198,215,275,293,297,311,341,355,364,372],"without":[116,306,358,366,374],"one.":[117],"public":[119],"health":[120],"significance":[121],"project":[124],"further":[127],"understanding":[129],"impacts":[132],"specific":[138,409],"METHODS:":[141],"Participants":[142],"were":[143,251],"recruited":[144],"from":[145],"multigenerational":[147],"family":[148,211,263],"where":[152],"mutation":[154,212,278],"identified":[157],"gene":[160],"GPD1L.":[161],"A":[162,187],"questionnaire":[163],"developed":[165],"ascertain":[167],"decisions.":[170],"Additionally,":[171],"36-Item":[173],"Short":[174],"Form":[175],"Health":[176],"Survey":[177],"(SF-36v2)":[178],"used":[180],"assess":[182],"RESULTS:":[186],"total":[188],"17":[190],"participants":[191,229],"agreed":[192],"enroll":[194],"age":[200],"range":[201],"36-89":[203],"years.":[204],"Ten":[205],"seventeen":[208],"had":[209,230,300],"GPD1L":[214],"seven":[216],"these":[218],"ten":[219],"displaying":[220],"phenotype":[223],"ECG.":[226],"Only":[227],"three":[228],"one":[234],"participant":[235],"considering":[237],"option":[239],"near":[242],"future.":[243],"reasons":[246],"choosing":[248],"either":[252],"due":[253],"sense":[256],"inevitability":[258],"necessity":[260],"or":[261,362],"benefit.":[264],"There":[265,282,344],"no":[267,285,312,346],"familial":[277],"without.":[281],"also":[284],"observed":[287],"asymptomatic":[289],"individuals":[292],"mutation.":[295],"Those":[296],"lower":[302],"MCS":[303],"than":[304],"(p-value":[309],"0.013)":[310],"other":[313,328,338],"significant":[314,394],"differences":[315],"observed.":[316],"CONCLUSION:":[317],"Reasons":[318],"underlying":[319],"decision-making":[321],"similar":[323,336],"seen":[326],"studies,":[329],"indicating":[330],"patients\u2019":[333],"experiences":[334],"groups":[340],"ICD.":[343],"statistical":[347],"genetic":[360],"diagnosis":[361],"symptoms.":[367],"indicates":[377],"does":[381],"life,":[385],"adding":[386],"more":[387],"evidence":[388],"support":[390],"psychosocial":[395],"aspect":[396],"management.":[400],"Additional":[401],"research":[402],"needed":[404],"better":[406],"address":[407],"needs":[410]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}