{"id":"https://openalex.org/W63618183","doi":null,"title":"Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener s granulomatosis as compared to rheumatoid arthritis and chronic Rhinosinusitis with nasal polyps.","display_name":"Nasal carriage of Staphylococcus aureus and endonasal activity in Wegener s granulomatosis as compared to rheumatoid arthritis and chronic Rhinosinusitis with nasal polyps.","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W63618183","mag":"63618183","pmid":"https://pubmed.ncbi.nlm.nih.gov/20412703"},"language":"en","primary_location":{"id":"pmid:20412703","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20412703","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental rheumatology","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5082668263","display_name":"Martin Laudien","orcid":"https://orcid.org/0000-0003-3342-3336","observed_orcids":["https://orcid.org/0000-0003-3342-3336"]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin Laudien","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, University of Kiel, Kiel, Germany. laudien@hno.uni-kiel.de"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, University of Kiel, Kiel, Germany. laudien@hno.uni-kiel.de","institution_ids":["https://openalex.org/I32021983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056741991","display_name":"Stefan D Gadola","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stefan D Gadola","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074009808","display_name":"Rainer Podschun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rainer Podschun","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114016103","display_name":"J\u00fcrgen Hedderich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J\u00fcrgen Hedderich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078705512","display_name":"Jens Paulsen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jens Paulsen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057094538","display_name":"Eva Reinhold\u2010Keller","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eva Reinhold-Keller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090509034","display_name":"Elena Csernok","orcid":"https://orcid.org/0000-0002-3640-3245","observed_orcids":["https://orcid.org/0000-0002-3640-3245"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elena Csernok","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075130510","display_name":"Petra Ambrosch","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Petra Ambrosch","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085617282","display_name":"Bernhard Hellmich","orcid":"https://orcid.org/0000-0002-8014-1801","observed_orcids":["https://orcid.org/0000-0002-8014-1801"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bernhard Hellmich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034799657","display_name":"Frank Moosig","orcid":"https://orcid.org/0000-0002-7341-9844","observed_orcids":["https://orcid.org/0000-0002-7341-9844"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frank Moosig","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110250002","display_name":"Wolfgang Ludwig Gross","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wolfgang L Gross","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087990440","display_name":"Hany Sahly","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hany Sahly","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5034748843","display_name":"Peter Lamprecht","orcid":"https://orcid.org/0000-0001-5929-868X","observed_orcids":["https://orcid.org/0000-0001-5929-868X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Lamprecht","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.9876,"has_fulltext":false,"cited_by_count":112,"citation_normalized_percentile":{"value":0.95428161,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"28","issue":"1 Suppl 57","first_page":"51","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.7134000062942505,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.7134000062942505,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10984","display_name":"Sinusitis and nasal conditions","score":0.22939999401569366,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11812","display_name":"Nasal Surgery and Airway Studies","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9660000205039978},{"id":"https://openalex.org/keywords/nasal-carriage","display_name":"nasal carriage","score":0.968999981880188},{"id":"https://openalex.org/keywords/granulomatosis-with-polyangiitis","display_name":"granulomatosis with polyangiitis","score":0.9760000109672546},{"id":"https://openalex.org/keywords/chronic-rhinosinusitis-with-nasal-polyps","display_name":"chronic rhinosinusitis with nasal polyps","score":0.921999990940094},{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":1.0},{"id":"https://openalex.org/keywords/recurrence","display_name":"recurrence","score":0.878000020980835},{"id":"https://openalex.org/keywords/upper-respiratory-tract-involvement","display_name":"upper respiratory tract involvement","score":0.7289999723434448},{"id":"https://openalex.org/keywords/chronic-inflammation","display_name":"chronic inflammation","score":0.5550000071525574},{"id":"https://openalex.org/keywords/granuloma-formation","display_name":"granuloma formation","score":0.9660000205039978}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9363847970962524},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.7777228355407715},{"id":"https://openalex.org/C2781390199","wikidata":"https://www.wikidata.org/wiki/Q8055111","display_name":"Nasal polyps","level":2,"score":0.7101728916168213},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.6544859409332275},{"id":"https://openalex.org/C2778311950","wikidata":"https://www.wikidata.org/wiki/Q7363","display_name":"Nose","level":2,"score":0.5656554102897644},{"id":"https://openalex.org/C105878827","wikidata":"https://www.wikidata.org/wiki/Q2041929","display_name":"Colonisation","level":3,"score":0.49221673607826233},{"id":"https://openalex.org/C2779644171","wikidata":"https://www.wikidata.org/wiki/Q13400765","display_name":"Respiratory tract","level":3,"score":0.45402154326438904},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.428352952003479},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3988623023033142},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.3706711232662201},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.36304593086242676},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.08881959319114685},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C2776927270","wikidata":"https://www.wikidata.org/wiki/Q815962","display_name":"Colonization","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D002353","descriptor_name":"Carrier State","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002908","descriptor_name":"Chronic Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006282","descriptor_name":"Health Personnel","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009297","descriptor_name":"Nasal Mucosa","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009298","descriptor_name":"Nasal Polyps","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D009298","descriptor_name":"Nasal Polyps","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012220","descriptor_name":"Rhinitis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D012220","descriptor_name":"Rhinitis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012852","descriptor_name":"Sinusitis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D012852","descriptor_name":"Sinusitis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D013203","descriptor_name":"Staphylococcal Infections","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D013211","descriptor_name":"Staphylococcus aureus","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D014890","descriptor_name":"Granulomatosis with Polyangiitis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D014890","descriptor_name":"Granulomatosis with Polyangiitis","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D015994","descriptor_name":"Incidence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019268","descriptor_name":"Antibodies, Antineutrophil Cytoplasmic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:20412703","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20412703","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and experimental rheumatology","raw_type":"Comparative Study"},{"id":"pmh:oai:eprints.soton.ac.uk:152827","doi":null,"is_oa":false,"landing_page_url":"https://eprints.soton.ac.uk/152827/","pdf_url":null,"source":{"id":"https://openalex.org/S4306401019","display_name":"ePrints Soton (University of Southampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I43439940","host_organization_name":"University of Southampton","host_organization_lineage":["https://openalex.org/I43439940"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"mag:63618183","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20412703","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W136400593","https://openalex.org/W1549001312","https://openalex.org/W1898943655","https://openalex.org/W1981778251","https://openalex.org/W1983346855","https://openalex.org/W1999395539","https://openalex.org/W2005611800","https://openalex.org/W2009706335","https://openalex.org/W2010937400","https://openalex.org/W2030578802","https://openalex.org/W2036380708","https://openalex.org/W2041565487","https://openalex.org/W2071298428","https://openalex.org/W2098533519","https://openalex.org/W2099258868","https://openalex.org/W2109207289","https://openalex.org/W2127837988","https://openalex.org/W2141776993","https://openalex.org/W2152348310","https://openalex.org/W2166954800","https://openalex.org/W2171950933","https://openalex.org/W2264075806","https://openalex.org/W2438141015","https://openalex.org/W2473080845","https://openalex.org/W2563968543"],"related_works":["https://openalex.org/W1989913257","https://openalex.org/W2041565487","https://openalex.org/W2905513411","https://openalex.org/W2133528790","https://openalex.org/W2468046430","https://openalex.org/W2561101340","https://openalex.org/W1981806197","https://openalex.org/W6983669071","https://openalex.org/W2099706141","https://openalex.org/W6946063712"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Nasal":[1,52],"colonisation":[2,24,118,198,211],"with":[3,25,64,71,74,80,119,149,193],"Staphylococcus":[4],"aureus":[5,27,56,121,154,197,210],"(S.":[6],"aureus)":[7],"has":[8],"been":[9],"implicated":[10],"in":[11,28,170,189,223,232],"Wegener's":[12],"granulomatosis":[13],"(WG)":[14],"disease":[15,35],"activity.":[16],"In":[17],"this":[18],"study,":[19],"the":[20,39,171,233],"frequency":[21,207],"of":[22,54,57,61,98,104,116,152,168,208,216],"nasal":[23,75,99,117,150,195],"S.":[26,55,120,153,196,209],"WG":[29,65,105,109,147,169,181,190,224],"was":[30,45,66,106],"compared":[31,67,122],"to":[32,47,68,123,138],"healthy":[33,128],"and":[34,88,95,101,127,142,176,200,225,229],"control":[36],"groups":[37],"for":[38],"first":[40,166],"time.":[41],"Moreover,":[42],"endonasal":[43,102,160],"activity":[44,103,161,188],"correlated":[46],"colonisation.":[48],"PATIENTS":[49],"AND":[50],"METHODS:":[51],"carriage":[53,100,151],"a":[58,214,217],"well-defined":[59],"group":[60],"89":[62],"patients":[63,70,79,110,125,140,148,182],"40":[69],"chronic":[72,227],"rhinosinusitis":[73],"polyps":[76],"(CRS),":[77],"35":[78],"rheumatoid":[81],"arthritis":[82],"(RA),":[83],"50":[84],"hospital":[85,93,132,143],"staff":[86,144],"members":[87,145],"25":[89],"subjects":[90,129],"without":[91,130,183],"regular":[92,131],"contact":[94,133],"correlation":[96],"analysis":[97],"performed.":[107],"RESULTS:":[108],"showed":[111],"significantly":[112,156,163],"higher":[113,157,177,194,202,206],"rates":[114,199],"(72%)":[115],"CRS":[124],"(28%)":[126],"(25%,":[134],"95%-CI),":[135],"but":[136],"not":[137],"RA":[139],"(46%)":[141],"(58%).":[146],"had":[155],"endoscopically":[158],"proven":[159],"(p=0.01),":[162],"more":[164],"often":[165],"manifestation":[167],"upper":[172,234],"respiratory":[173,235],"tract":[174],"(p=0.02)":[175],"relapse-rates":[178],"(p=0.052)":[179],"than":[180],"such":[184],"carriage.":[185],"CONCLUSIONS:":[186],"Endonasal":[187],"is":[191],"associated":[192],"subsequent":[201],"relapse":[203],"rates.":[204],"The":[205],"could":[212],"be":[213],"consequence":[215],"recently":[218],"shown":[219],"mucosal":[220],"barrier":[221],"defect":[222],"facilitate":[226],"inflammation":[228],"granuloma":[230],"formation":[231],"tract.":[236]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":13},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}