{"id":"https://openalex.org/W63553259","doi":null,"title":"Inhibition of (Na(+)/K(+))-ATPase by Cibacron Blue 3G-A and its analogues.","display_name":"Inhibition of (Na(+)/K(+))-ATPase by Cibacron Blue 3G-A and its analogues.","publication_year":2006,"publication_date":"2006-12-01","ids":{"openalex":"https://openalex.org/W63553259","mag":"63553259","pmid":"https://pubmed.ncbi.nlm.nih.gov/17356235"},"language":"en","primary_location":{"id":"pmid:17356235","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17356235","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General physiology and biophysics","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004536543","display_name":"Albert Breier","orcid":"https://orcid.org/0000-0003-2174-786X","observed_orcids":["https://orcid.org/0000-0003-2174-786X"]},"institutions":[{"id":"https://openalex.org/I207624831","display_name":"Slovak Academy of Sciences","ror":"https://ror.org/03h7qq074","country_code":"SK","type":"government","lineage":["https://openalex.org/I207624831"]},{"id":"https://openalex.org/I4405255183","display_name":"Institute of Molecular Physiology and Genetics of the Slovak Academy of Sciences","ror":"https://ror.org/02q6q1660","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210101919","https://openalex.org/I4405255183"]}],"countries":["SK"],"is_corresponding":false,"raw_author_name":"A Breier","raw_affiliation_strings":["Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Vl\u00e1rska 5, 83334 Bratislava 37, Slovakia. albert.breier@savba.sk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Vl\u00e1rska 5, 83334 Bratislava 37, Slovakia. albert.breier@savba.sk","institution_ids":["https://openalex.org/I207624831","https://openalex.org/I4405255183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113590692","display_name":"Vierka Boh\u00e1\u010dov\u00e1","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Boh\u00e1cov\u00e1","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5044915654","display_name":"Peter Do\u010dolomansk\u00fd","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Docolomansk\u00fd","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1123,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.39114119,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"25","issue":"4","first_page":"439","last_page":"53"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.1281999945640564,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.1281999945640564,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":0.11460000276565552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12412","display_name":"Enzyme function and inhibition","score":0.07029999792575836,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/na-k-atpase","display_name":"Na+/K+-ATPase","score":0.8920000195503235},{"id":"https://openalex.org/keywords/anthraquinone-dyes","display_name":"anthraquinone dyes","score":0.9229999780654907},{"id":"https://openalex.org/keywords/reactive-blue-2","display_name":"reactive blue 2","score":0.8429999947547913},{"id":"https://openalex.org/keywords/remazol-brilliant-blue-r","display_name":"Remazol Brilliant Blue R","score":0.9900000095367432},{"id":"https://openalex.org/keywords/competitive-inhibition","display_name":"competitive inhibition","score":0.7599999904632568},{"id":"https://openalex.org/keywords/atp-binding-site","display_name":"ATP binding site","score":0.9039999842643738},{"id":"https://openalex.org/keywords/molar-refractivity","display_name":"molar refractivity","score":0.7889999747276306},{"id":"https://openalex.org/keywords/structure-activity-relationship","display_name":"structure-activity relationship","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7821164131164551},{"id":"https://openalex.org/C2776568683","wikidata":"https://www.wikidata.org/wiki/Q23005640","display_name":"Moiety","level":2,"score":0.6909316778182983},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.6210602521896362},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.6007130146026611},{"id":"https://openalex.org/C2778913731","wikidata":"https://www.wikidata.org/wiki/Q423174","display_name":"Anthraquinone","level":2,"score":0.5744152665138245},{"id":"https://openalex.org/C512185932","wikidata":"https://www.wikidata.org/wiki/Q28745","display_name":"Nucleotide","level":3,"score":0.5521442890167236},{"id":"https://openalex.org/C2776303721","wikidata":"https://www.wikidata.org/wiki/Q419563","display_name":"Triazine","level":2,"score":0.5504631996154785},{"id":"https://openalex.org/C23265538","wikidata":"https://www.wikidata.org/wiki/Q300033","display_name":"ATPase","level":3,"score":0.5305055975914001},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.5151516199111938},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4620264172554016},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08503445982933044},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000254","descriptor_name":"Sodium-Potassium-Exchanging ATPase","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004791","descriptor_name":"Enzyme Inhibitors","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D014227","descriptor_name":"Triazines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":1,"locations":[{"id":"pmid:17356235","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17356235","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"General physiology and biophysics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W65718103","https://openalex.org/W132177117","https://openalex.org/W185434317","https://openalex.org/W1514872438","https://openalex.org/W1516001873","https://openalex.org/W1968436532","https://openalex.org/W1969423045","https://openalex.org/W1969856237","https://openalex.org/W1978601437","https://openalex.org/W1979321186","https://openalex.org/W1987415721","https://openalex.org/W1993244298","https://openalex.org/W2005820313","https://openalex.org/W2007615331","https://openalex.org/W2013980100","https://openalex.org/W2021201933","https://openalex.org/W2023142797","https://openalex.org/W2031423487","https://openalex.org/W2039674534","https://openalex.org/W2051413330","https://openalex.org/W2052675384","https://openalex.org/W2057431697","https://openalex.org/W2059727862","https://openalex.org/W2067230356","https://openalex.org/W2068604072","https://openalex.org/W2073156303","https://openalex.org/W2078075319","https://openalex.org/W2086276866","https://openalex.org/W2088442562","https://openalex.org/W2094890426","https://openalex.org/W2137670899","https://openalex.org/W2152503709","https://openalex.org/W2183723165","https://openalex.org/W2187048525","https://openalex.org/W2187976638","https://openalex.org/W2188160299","https://openalex.org/W2189003812","https://openalex.org/W2221986019","https://openalex.org/W2341560941","https://openalex.org/W2398039222","https://openalex.org/W2409343044","https://openalex.org/W2415062160","https://openalex.org/W2434815139","https://openalex.org/W2469470973","https://openalex.org/W2501088886","https://openalex.org/W4237796760"],"related_works":["https://openalex.org/W2469470973","https://openalex.org/W2039674534","https://openalex.org/W2028199497","https://openalex.org/W1990769463","https://openalex.org/W2087326494","https://openalex.org/W2416019641","https://openalex.org/W1554578020","https://openalex.org/W2055458948","https://openalex.org/W2069227327","https://openalex.org/W1984804700"],"abstract_inverted_index":{"A":[0],"specific":[1],"feature":[2],"of":[3,29,43,70,114,141,147,176,182,194,205,207,212,215,223,227,243,246,264,269,274,280,286],"anthraquinone":[4,208],"dyes":[5],"(AD)":[6],"is":[7,137],"to":[8,20,131,139,237,276],"mimic":[9],"the":[10,35,38,68,92,99,105,132,144,161,164,173,241,244,249],"adenine":[11,247],"nucleotides":[12],"ATP,":[13],"ADP,":[14],"NAD":[15],"and":[16,32,59,108,121,155,178,184,209,248,295],"NADH,":[17],"enabling":[18],"them":[19],"act":[21],"as":[22,240],"ligands":[23],"in":[24,77,172,266],"interaction":[25,190],"with":[26,191,283,291],"nucleotide-binding":[27],"sites":[28],"several":[30],"enzymes":[31],"receptors.":[33],"In":[34],"present":[36],"study,":[37],"interactions":[39],"and/or":[40],"inhibitory":[41,145],"effects":[42],"eight":[44],"AD,":[45,118],"including":[46],"Cibacron":[47],"Blue":[48,51,54,57,62,65],"3G-A":[49],"(Reactive":[50,56,64],"2),":[52],"Procion":[53],"MX-R":[55],"4)":[58],"Remazol":[60],"Brilliant":[61],"R":[63],"19)":[66],"on":[67,231,253],"activity":[69],"(Na(+)/K(+))-ATPase":[71,133,150,281],"were":[72,124,235],"investigated.":[73],"The":[74,272],"AD":[75,148,185,217,234,265,275],"used":[76],"this":[78,224],"paper":[79],"could":[80,167,258],"be":[81,168,198,238,259],"divided":[82],"into":[83],"two":[84,229],"groups:":[85],"i)":[86],"AD1-AD4":[87],"that":[88,97,202],"do":[89],"not":[90],"contain":[91,98],"triazine":[93,100],"moiety;":[94],"ii)":[95],"AD5-AD8":[96],"moiety.":[101],"Interaction":[102],"affinity":[103,273],"between":[104,143],"respective":[106,216],"dye":[107],"(Na+/K+)-ATPase":[109],"was":[110],"characterized":[111],"by":[112,200],"means":[113],"enzyme":[115],"kinetics.":[116],"All":[117],"excluding":[119],"AD1":[120],"AD2":[122],"(which":[123],"practically":[125],"ineffective)":[126],"exerted":[127],"effective":[128,233],"competitive":[129],"inhibition":[130,222],"activity.":[134],"Present":[135],"study":[136],"devoted":[138],"elucidation":[140],"relationship":[142],"efficacy":[146],"against":[149],"activity,":[151],"their":[152,156,189],"acid-basic":[153],"properties":[154],"three":[157],"dimensional":[158],"structure.":[159],"From":[160],"results":[162],"obtained,":[163],"following":[165],"conclusions":[166],"driven:":[169],"1.":[170],"Similarities":[171],"mutual":[174,203],"position":[175,204],"positively":[177],"negatively":[179],"charged":[180],"parts":[181],"ATP":[183,254,277],"are":[186],"responsible":[187,260],"for":[188,221,261],"ATP-binding":[192,267],"site":[193,279],"(Na(+)/K(+))-ATPase.":[195,270],"This":[196,256],"may":[197],"documented":[199],"fact":[201],"1-aminogroup":[206],"-SO3(-)":[210],"group":[211,252],"benzenesulphonate":[213],"part":[214],"plays":[218],"crucial":[219],"role":[220],"enzyme.":[225],"Distances":[226],"these":[228],"groups":[230],"all":[232],"found":[236],"similar":[239],"distance":[242],"6-aminogroup":[245],"second":[250],"phosphate":[251],"molecule.":[255],"similarity":[257],"biomimetic":[262],"recognition":[263],"loci":[268],"2.":[271],"binding":[278],"increases":[282],"increasing":[284,292],"values":[285],"molar":[287],"refractivity,":[288],"i.":[289],"e.,":[290],"molecular":[293],"volume":[294],"polarizability.":[296]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}