{"id":"https://openalex.org/W6324909","doi":null,"title":"Repeated Drug Exposure Disrupts Rat Hippocampal Neurons During Adolescent Brain Development","display_name":"Repeated Drug Exposure Disrupts Rat Hippocampal Neurons During Adolescent Brain Development","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W6324909","mag":"6324909"},"language":"en","primary_location":{"id":"pmh:oai:publications.lakeforest.edu:gss-1018","doi":null,"is_oa":false,"landing_page_url":"https://publications.lakeforest.edu/gss/gss2013/program/19","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Steven Galovich Memorial Student Symposium","raw_type":"text"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050987421","display_name":"Kimberly C. Diah","orcid":"https://orcid.org/0000-0003-3417-0473","observed_orcids":["https://orcid.org/0000-0003-3417-0473"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"K Diah","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5050987421"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00104384,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.7509999871253967,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.7509999871253967,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.1428000032901764,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.016100000590085983,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adolescent-drug-exposure","display_name":"adolescent drug exposure","score":0.9340000152587891},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.7820000052452087},{"id":"https://openalex.org/keywords/gabaergic-interneurons","display_name":"GABAergic interneurons","score":0.9950000047683716},{"id":"https://openalex.org/keywords/cocaine","display_name":"cocaine","score":0.5400000214576721},{"id":"https://openalex.org/keywords/glutamate-receptor-agonists","display_name":"glutamate receptor agonists","score":0.9620000123977661},{"id":"https://openalex.org/keywords/adolescent-brain-development","display_name":"adolescent brain development","score":0.8709999918937683},{"id":"https://openalex.org/keywords/neurodevelopmental-disruption","display_name":"neurodevelopmental disruption","score":0.6470000147819519},{"id":"https://openalex.org/keywords/neuropsychiatric-disorders","display_name":"neuropsychiatric disorders","score":0.718999981880188},{"id":"https://openalex.org/keywords/rat-model","display_name":"rat model","score":0.37400001287460327}],"concepts":[{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.7905011177062988},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6290689706802368},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.552654504776001},{"id":"https://openalex.org/C2984223407","wikidata":"https://www.wikidata.org/wiki/Q1345738","display_name":"Brain development","level":2,"score":0.5451152324676514},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.5152540802955627},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4470682144165039},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.43134909868240356},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37050116062164307},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2481251060962677}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:publications.lakeforest.edu:gss-1018","doi":null,"is_oa":false,"landing_page_url":"https://publications.lakeforest.edu/gss/gss2013/program/19","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Steven Galovich Memorial Student Symposium","raw_type":"text"},{"id":"mag:6324909","doi":null,"is_oa":false,"landing_page_url":"http://publications.lakeforest.edu/gss/gss2013/program/19/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2084965555","https://openalex.org/W2943477488","https://openalex.org/W2063976611","https://openalex.org/W4406057459","https://openalex.org/W2541718129","https://openalex.org/W2028932421","https://openalex.org/W2061969741","https://openalex.org/W2068481683","https://openalex.org/W2540359722","https://openalex.org/W2067240884"],"abstract_inverted_index":{"Exposure":[0],"to":[1,10,69,77],"addictive":[2],"and":[3,22,71,96],"non-addictive":[4],"drugs":[5,31,52],"during":[6,24],"adolescence":[7],"increases":[8],"susceptibility":[9],"neuropsychiatric":[11],"disorders.":[12],"GABA":[13,33,57,67],"interneurons":[14,34,58,68],"mediate":[15],"maturation":[16],"of":[17,66,94],"the":[18,36],"prefrontal":[19],"cortex":[20],"(PFC)":[21],"hippocampus":[23,42],"adolescence.":[25],"Recent":[26],"findings":[27],"indicate":[28],"that":[29],"these":[30],"disrupt":[32],"in":[35,59,84],"maturing":[37],"PFC,":[38],"but":[39,75],"effects":[40,54],"on":[41,55],"are":[43],"unknown.":[44],"For":[45],"my":[46],"thesis,":[47],"I":[48,62],"investigated":[49],"three":[50],"such":[51],"for":[53],"hippocampal":[56],"adolescent":[60],"rats.":[61],"found":[63],"developmental":[64],"disregulation":[65],"cocaine":[70],"a":[72,78],"glutamate":[73],"agonist,":[74],"not":[76],"marijuana-mimic.":[79],"This":[80],"research":[81],"was":[82],"performed":[83],"Dr.":[85],"Kuei":[86],"Yuan":[87],"Tseng's":[88],"Laboratory":[89],"at":[90],"Rosalind":[91],"Franklin":[92],"University":[93],"Medicine":[95],"Science.":[97]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}