{"id":"https://openalex.org/W632023","doi":"https://doi.org/10.1007/978-1-4614-3209-8_106","title":"Neuroprotective Effects of Low Level Electrical Stimulation Therapy on Retinal Degeneration","display_name":"Neuroprotective Effects of Low Level Electrical Stimulation Therapy on Retinal Degeneration","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W632023","doi":"https://doi.org/10.1007/978-1-4614-3209-8_106","mag":"632023","pmid":"https://pubmed.ncbi.nlm.nih.gov/24664779"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4614-3209-8_106","doi":"https://doi.org/10.1007/978-1-4614-3209-8_106","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4614-3209-8_106","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4254722098","display_name":"Retinal Degenerative Diseases"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012234271","display_name":"Machelle T. Pardue","orcid":"https://orcid.org/0000-0001-8738-6839","observed_orcids":["https://orcid.org/0000-0001-8738-6839"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Machelle T. Pardue","raw_affiliation_strings":["Ophthalmology, School of Medicine, Emory University, Atlanta, GA, USA, mpardue@emory.edu","Ophthalmology, School of Medicine, Emory University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology, School of Medicine, Emory University, Atlanta, GA, USA, mpardue@emory.edu","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Ophthalmology, School of Medicine, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065909406","display_name":"Vincent T. Ciavatta","orcid":"https://orcid.org/0000-0002-1615-0826","observed_orcids":["https://orcid.org/0000-0002-1615-0826"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vincent T. Ciavatta","raw_affiliation_strings":["Ophthalmology, School of Medicine, Emory University, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ophthalmology, School of Medicine, Emory University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087071173","display_name":"John R. Hetling","orcid":"https://orcid.org/0000-0002-1917-978X","observed_orcids":["https://orcid.org/0000-0002-1917-978X"]},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John R. Hetling","raw_affiliation_strings":["Bioengineering, University of Illinois at Chicago, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioengineering, University of Illinois at Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I39422238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5012234271"],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":null,"apc_paid":null,"fwci":1.692,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.82280965,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"801","issue":null,"first_page":"845","last_page":"851"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13869","display_name":"Ocular and Laser Science Research","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/low-level-electrical-stimulation","display_name":"low-level electrical stimulation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/retinal-degeneration","display_name":"retinal degeneration","score":0.949999988079071},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.968999981880188},{"id":"https://openalex.org/keywords/transcorneal-electrical-stimulation","display_name":"transcorneal electrical stimulation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/photoreceptors","display_name":"photoreceptors","score":0.9800000190734863},{"id":"https://openalex.org/keywords/retinal-ganglion-cells","display_name":"retinal ganglion cells","score":1.0},{"id":"https://openalex.org/keywords/visual-acuity","display_name":"visual acuity","score":0.9290000200271606},{"id":"https://openalex.org/keywords/growth-factor-expression","display_name":"growth factor expression","score":0.8579999804496765},{"id":"https://openalex.org/keywords/clinical-translation","display_name":"clinical translation","score":0.5730000138282776}],"concepts":[{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.8103249073028564},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.6944805383682251},{"id":"https://openalex.org/C2781040256","wikidata":"https://www.wikidata.org/wiki/Q7316761","display_name":"Retinal degeneration","level":3,"score":0.6746804118156433},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.6537482142448425},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.642857551574707},{"id":"https://openalex.org/C2777624874","wikidata":"https://www.wikidata.org/wiki/Q927337","display_name":"Retinal ganglion cell","level":3,"score":0.6033933162689209},{"id":"https://openalex.org/C2779918689","wikidata":"https://www.wikidata.org/wiki/Q3771842","display_name":"Stimulus (psychology)","level":2,"score":0.6033901572227478},{"id":"https://openalex.org/C2777093970","wikidata":"https://www.wikidata.org/wiki/Q169342","display_name":"Retina","level":2,"score":0.5025644302368164},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.49154648184776306},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4559810757637024},{"id":"https://openalex.org/C158383150","wikidata":"https://www.wikidata.org/wiki/Q3149439","display_name":"Retinal implant","level":3,"score":0.4287915825843811},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23230215907096863},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.23194652795791626},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004599","descriptor_name":"Electric Stimulation Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012162","descriptor_name":"Retinal Degeneration","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D012165","descriptor_name":"Retinal Ganglion Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020419","descriptor_name":"Photoreceptor Cells, Vertebrate","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D020419","descriptor_name":"Photoreceptor Cells, Vertebrate","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-4614-3209-8_106","doi":"https://doi.org/10.1007/978-1-4614-3209-8_106","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4614-3209-8_106","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},{"id":"pmid:24664779","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24664779","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in experimental medicine and biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.6700000166893005,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1026921058","https://openalex.org/W1551140393","https://openalex.org/W1957804270","https://openalex.org/W1973520192","https://openalex.org/W1980691020","https://openalex.org/W2006328994","https://openalex.org/W2008025759","https://openalex.org/W2015019097","https://openalex.org/W2017515548","https://openalex.org/W2018039000","https://openalex.org/W2018660789","https://openalex.org/W2032610026","https://openalex.org/W2039226314","https://openalex.org/W2044024607","https://openalex.org/W2050381624","https://openalex.org/W2053619184","https://openalex.org/W2053780851","https://openalex.org/W2055835811","https://openalex.org/W2072504942","https://openalex.org/W2076353169","https://openalex.org/W2088517594","https://openalex.org/W2090057828","https://openalex.org/W2092856088","https://openalex.org/W2093154699","https://openalex.org/W2095891880","https://openalex.org/W2107650178","https://openalex.org/W2123805988","https://openalex.org/W2149796318","https://openalex.org/W2333601102"],"related_works":["https://openalex.org/W2425058220","https://openalex.org/W2333601102","https://openalex.org/W2612496944","https://openalex.org/W2501272032","https://openalex.org/W4309710977","https://openalex.org/W2123805988","https://openalex.org/W3188635078","https://openalex.org/W6946446552","https://openalex.org/W2017515548","https://openalex.org/W1551140393"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}