{"id":"https://openalex.org/W62457274","doi":null,"title":"Hypergastrinemia and enterochromaffin-like cell hyperplasia.","display_name":"Hypergastrinemia and enterochromaffin-like cell hyperplasia.","publication_year":1998,"publication_date":"1998-05-01","ids":{"openalex":"https://openalex.org/W62457274","mag":"62457274","pmid":"https://pubmed.ncbi.nlm.nih.gov/10461360","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2578981"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2578981","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2578981/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2578981/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2578981/pdf/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111714740","display_name":"G. Delle Fave","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Delle Fave","raw_affiliation_strings":["Cattedra di Gastroenterologia, Universit\u00e0 La Sapienza, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cattedra di Gastroenterologia, Universit\u00e0 La Sapienza, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049004748","display_name":"Massimo Marignani","orcid":"https://orcid.org/0000-0002-8912-9972","observed_orcids":["https://orcid.org/0000-0002-8912-9972"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"M Marignani","raw_affiliation_strings":["University of Rome \u201cLa Sapienza \u201d"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome \u201cLa Sapienza \u201d","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018995122","display_name":"Arianna Moretti","orcid":"https://orcid.org/0009-0008-6157-643X","observed_orcids":["https://orcid.org/0009-0008-6157-643X"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A Moretti","raw_affiliation_strings":["University of Rome \u201cLa Sapienza \u201d"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome \u201cLa Sapienza \u201d","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110714121","display_name":"G. D\u2019Ambra","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G D'Ambra","raw_affiliation_strings":["University of Rome \u201cLa Sapienza \u201d"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome \u201cLa Sapienza \u201d","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032907890","display_name":"Giovanni Martino","orcid":"https://orcid.org/0000-0003-3957-6720","observed_orcids":["https://orcid.org/0000-0003-3957-6720"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"G Martino","raw_affiliation_strings":["University of Rome \u201cLa Sapienza \u201d"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome \u201cLa Sapienza \u201d","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035332783","display_name":"Bruno Annibale","orcid":"https://orcid.org/0000-0001-9120-5957","observed_orcids":["https://orcid.org/0000-0001-9120-5957"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"B Annibale","raw_affiliation_strings":["University of Rome \u201cLa Sapienza \u201d"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome \u201cLa Sapienza \u201d","institution_ids":["https://openalex.org/I861853513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I861853513"],"apc_list":null,"apc_paid":null,"fwci":0.3701,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.60688015,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"71","issue":"3-4","first_page":"291","last_page":"301"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.9692000150680542,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.017400000244379044,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11378","display_name":"Gastrointestinal Bleeding Diagnosis and Treatment","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypergastrinemia","display_name":"hypergastrinemia","score":0.921999990940094},{"id":"https://openalex.org/keywords/enterochromaffin-like-cells","display_name":"enterochromaffin-like cells","score":0.9700000286102295},{"id":"https://openalex.org/keywords/ecl-cell-hyperplasia","display_name":"ECL cell hyperplasia","score":0.9610000252723694},{"id":"https://openalex.org/keywords/gastrin","display_name":"gastrin","score":0.8650000095367432},{"id":"https://openalex.org/keywords/zollinger-ellison-syndrome","display_name":"Zollinger-Ellison syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/gastrinoma","display_name":"gastrinoma","score":0.44600000977516174},{"id":"https://openalex.org/keywords/gastrin-secretion","display_name":"gastrin secretion","score":0.5040000081062317}],"concepts":[{"id":"https://openalex.org/C2776986829","wikidata":"https://www.wikidata.org/wiki/Q407181","display_name":"Gastrin","level":3,"score":0.8403477072715759},{"id":"https://openalex.org/C186199130","wikidata":"https://www.wikidata.org/wiki/Q3329719","display_name":"Enterochromaffin-like cell","level":4,"score":0.773561954498291},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.708483874797821},{"id":"https://openalex.org/C2777562237","wikidata":"https://www.wikidata.org/wiki/Q835051","display_name":"Hyperplasia","level":2,"score":0.6944103240966797},{"id":"https://openalex.org/C103395026","wikidata":"https://www.wikidata.org/wiki/Q5380231","display_name":"Enteroendocrine cell","level":4,"score":0.6115219593048096},{"id":"https://openalex.org/C2780342937","wikidata":"https://www.wikidata.org/wiki/Q1826391","display_name":"Atrophic gastritis","level":4,"score":0.597084641456604},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5851740837097168},{"id":"https://openalex.org/C131253125","wikidata":"https://www.wikidata.org/wiki/Q609361","display_name":"Antrum","level":3,"score":0.5645059943199158},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5530843138694763},{"id":"https://openalex.org/C90423213","wikidata":"https://www.wikidata.org/wiki/Q568290","display_name":"Enterochromaffin cell","level":4,"score":0.5507208704948425},{"id":"https://openalex.org/C2777351272","wikidata":"https://www.wikidata.org/wiki/Q218712","display_name":"Zollinger-Ellison syndrome","level":2,"score":0.5485020279884338},{"id":"https://openalex.org/C2779970781","wikidata":"https://www.wikidata.org/wiki/Q340548","display_name":"Achlorhydria","level":3,"score":0.533584475517273},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.5201807022094727},{"id":"https://openalex.org/C2781443798","wikidata":"https://www.wikidata.org/wiki/Q383249","display_name":"Gastric mucosa","level":3,"score":0.4656885862350464},{"id":"https://openalex.org/C119811328","wikidata":"https://www.wikidata.org/wiki/Q2987004","display_name":"G cell","level":4,"score":0.43045103549957275},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.416240394115448},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4134926497936249},{"id":"https://openalex.org/C2778677798","wikidata":"https://www.wikidata.org/wiki/Q183130","display_name":"Gastritis","level":3,"score":0.2717832922935486},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.15612348914146423},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.1505589783191681},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005755","descriptor_name":"Gastrins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005757","descriptor_name":"Gastritis, Atrophic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005757","descriptor_name":"Gastritis, Atrophic","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006965","descriptor_name":"Hyperplasia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011706","descriptor_name":"Pyloric Antrum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015043","descriptor_name":"Zollinger-Ellison Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015043","descriptor_name":"Zollinger-Ellison Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018753","descriptor_name":"Diet, Protein-Restricted","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019861","descriptor_name":"Enterochromaffin-like Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019861","descriptor_name":"Enterochromaffin-like Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D019863","descriptor_name":"Gastrin-Secreting Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":5,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2578981","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2578981/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2578981/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},{"id":"pmid:10461360","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10461360","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Yale journal of biology and medicine","raw_type":"Journal Article"},{"id":"pmh:oai:iris.uniroma1.it:11573/481207","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11573/481207","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.uniroma1.it:11573/93862","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11573/93862","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:62457274","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10461360","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2578981","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2578981/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2578981/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320322875","display_name":"Universit\u00e0 degli Studi di Parma","ror":"https://ror.org/02k7wn190"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W62457274.pdf","grobid_xml":"https://content.openalex.org/works/W62457274.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W1488629461","https://openalex.org/W1676960647","https://openalex.org/W1826781214","https://openalex.org/W1881509706","https://openalex.org/W1964788924","https://openalex.org/W1965379407","https://openalex.org/W1966954405","https://openalex.org/W1970314933","https://openalex.org/W1972627435","https://openalex.org/W1975348700","https://openalex.org/W1983447573","https://openalex.org/W1995375941","https://openalex.org/W2024797832","https://openalex.org/W2028682170","https://openalex.org/W2035023169","https://openalex.org/W2041490128","https://openalex.org/W2057486293","https://openalex.org/W2078840077","https://openalex.org/W2091515529","https://openalex.org/W2094598707","https://openalex.org/W2097836571","https://openalex.org/W2143274858","https://openalex.org/W2152152769","https://openalex.org/W2280278293","https://openalex.org/W2306085278","https://openalex.org/W2340530217","https://openalex.org/W2414711526","https://openalex.org/W2415626809","https://openalex.org/W2442854279"],"related_works":["https://openalex.org/W2051530867","https://openalex.org/W2408730022","https://openalex.org/W2144770355","https://openalex.org/W2150934576","https://openalex.org/W7096882313","https://openalex.org/W1990618940","https://openalex.org/W4251039741","https://openalex.org/W2078840077","https://openalex.org/W1562288220","https://openalex.org/W2010390058"],"abstract_inverted_index":{"UNLABELLED:":[0],"The":[1,35,128,249],"enterochromaffin-like":[2],"(ECL)":[3],"cells,":[4],"the":[5,11,15,19,41,60,89,120,144,160,170,175,220,227,255,281,283,286,289,302,307,311],"most":[6,36],"frequent":[7],"endocrine":[8,213],"cells":[9,25,95,182],"of":[10,14,22,32,43,59,91,93,99,111,122,146,162,169,177,180,191,202,251,257,271,291,293,304,313],"oxyntic":[12],"mucosa":[13,173],"stomach,":[16],"are":[17],"under":[18],"trophic":[20],"stimulus":[21],"gastrin.":[23],"These":[24],"undergo":[26],"a":[27,51,56,109],"hyperplastic":[28,44],"increase":[29],"in":[30,50,70,131,317],"variety":[31],"hypergastrinemic":[33,72,192],"diseases.":[34,156],"widely":[37],"accepted":[38],"nomenclature":[39],"for":[40,174,208,235],"description":[42],"proliferation":[45],"has":[46],"been":[47],"retrospectively":[48],"arranged":[49],"sequence":[52],"presumed":[53],"to":[54,68,96,153,310],"reflect":[55],"temporal":[57],"evolution":[58],"proliferative":[61],"process.":[62],"A":[63,189,262],"comparative,":[64],"prospective":[65],"study":[66,133],"aimed":[67,152],"verify,":[69],"human":[71],"diseases":[73],"such":[74],"as":[75,306],"atrophic":[76],"body":[77,172,212],"gastritis":[78],"(ABG),":[79],"Zollinger-Ellison":[80],"syndrome":[81],"(ZES)":[82],"and":[83,117,138,184,205,231,238,269],"antral":[84],"gastrin":[85,100,187,203,267,284,305],"cell":[86,315],"hyperfunction":[87],"(AGCH),":[88],"effect":[90],"exposure":[92],"ECL":[94,181,294,314],"different":[97],"pattern":[98,179,259],"hypersecretion,":[101],"is":[102,288],"lacking.":[103],"To":[104],"this":[105,132],"purpose,":[106],"we":[107],"studied":[108],"series":[110],"consecutive":[112],"patients":[113,129,158,193,217,243,253],"with":[114,166],"ABG,":[115,135],"ZES":[116,137,228],"AGCH":[118,216],"at":[119,159],"time":[121,161],"first":[123],"diagnosis.":[124],"MATERIAL":[125],"AND":[126],"METHODS:":[127],"included":[130],"(124":[134],"18":[136],"10":[139],"AGCH)":[140],"were":[141],"selected":[142],"on":[143],"basis":[145],"two":[147,247],"previously":[148],"performed":[149],"screening":[150],"studies":[151],"diagnose":[154],"these":[155,246],"All":[157],"diagnosis":[163],"underwent":[164],"gastroscopy,":[165],"multiple":[167],"biopsies":[168],"gastric":[171,211],"evaluation":[176],"qualitative":[178],"hyperplasia,":[183],"basal":[185],"fasting":[186,266],"determination.":[188],"sample":[190],"from":[194],"each":[195],"group":[196],"was":[197],"further":[198],"investigated":[199],"by":[200],"meal-stimulation":[201],"secretion":[204],"quantitative":[206],"morphometry":[207],"CgA":[209],"positive":[210],"cells.":[214],"RESULTS:":[215],"showed":[218,244,254],"only":[219,245],"normal":[221],"or":[222],"simple":[223,230],"hyperplasia":[224,272,295,316],"pattern.":[225,296],"In":[226,297],"group,":[229],"linear":[232],"grades":[233],"accounted":[234],"38.4":[236],"percent":[237],"46.1":[239],"percent,":[240],"respectively.":[241],"MEN-I":[242],"patterns.":[248],"majority":[250],"ABG":[252],"presence":[256],"micronodular":[258],"(59.7":[260],"percent).":[261],"correlation":[263],"analysis":[264],"between":[265],"levels":[268],"grade":[270],"(r":[273],"=":[274],"0.5580,":[275],"p":[276],"<":[277],"0.0001),":[278],"indicates":[279],"that":[280],"greater":[282],"levels,":[285],"higher":[287],"degree":[290],"severity":[292],"conclusion,":[298],"our":[299],"data":[300],"support":[301],"role":[303],"selective":[308],"contributor":[309],"progression":[312],"humans.":[318]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}