{"id":"https://openalex.org/W61688430","doi":null,"title":"Misdiagnosis of bipolar disorder.","display_name":"Misdiagnosis of bipolar disorder.","publication_year":2005,"publication_date":"2005-10-01","ids":{"openalex":"https://openalex.org/W61688430","mag":"61688430","pmid":"https://pubmed.ncbi.nlm.nih.gov/16232009"},"language":"en","primary_location":{"id":"pmid:16232009","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16232009","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of managed care","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064278484","display_name":"Roy H. Perlis","orcid":"https://orcid.org/0000-0002-5862-6757","observed_orcids":["https://orcid.org/0000-0002-5862-6757"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Roy H Perlis","raw_affiliation_strings":["Harvard Medical School, Boston, MA 02114, USA. rperlis@partners.org"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard Medical School, Boston, MA 02114, USA. rperlis@partners.org","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5064278484"],"corresponding_institution_ids":["https://openalex.org/I136199984"],"apc_list":null,"apc_paid":null,"fwci":1.5088,"has_fulltext":false,"cited_by_count":159,"citation_normalized_percentile":{"value":0.80182053,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":100},"biblio":{"volume":"11","issue":"9 Suppl","first_page":"S271","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10854","display_name":"Bipolar Disorder and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11093","display_name":"Personality Disorders and Psychopathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bipolar-disorder","display_name":"bipolar disorder","score":1.0},{"id":"https://openalex.org/keywords/misdiagnosis","display_name":"misdiagnosis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":0.9879999756813049},{"id":"https://openalex.org/keywords/mania","display_name":"mania","score":0.5529999732971191},{"id":"https://openalex.org/keywords/hypomania","display_name":"hypomania","score":0.9900000095367432},{"id":"https://openalex.org/keywords/psychiatric-comorbidity","display_name":"psychiatric comorbidity","score":0.9359999895095825},{"id":"https://openalex.org/keywords/anxiety-disorders","display_name":"anxiety disorders","score":0.824999988079071},{"id":"https://openalex.org/keywords/substance-use-disorders","display_name":"substance use disorders","score":0.9980000257492065},{"id":"https://openalex.org/keywords/patient-insight","display_name":"patient insight","score":0.7639999985694885},{"id":"https://openalex.org/keywords/clinical-screening","display_name":"clinical screening","score":0.41499999165534973},{"id":"https://openalex.org/keywords/treatment-outcomes","display_name":"treatment outcomes","score":0.5099999904632568}],"concepts":[{"id":"https://openalex.org/C2778567577","wikidata":"https://www.wikidata.org/wiki/Q188611","display_name":"Hypomania","level":5,"score":0.9464273452758789},{"id":"https://openalex.org/C2776174506","wikidata":"https://www.wikidata.org/wiki/Q131755","display_name":"Bipolar disorder","level":3,"score":0.8690459728240967},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8154991269111633},{"id":"https://openalex.org/C2776809841","wikidata":"https://www.wikidata.org/wiki/Q185935","display_name":"Mania","level":4,"score":0.8029106855392456},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.618364155292511},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.5840948820114136},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.5658664703369141},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.546954870223999},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.4937227666378021},{"id":"https://openalex.org/C145734003","wikidata":"https://www.wikidata.org/wiki/Q7242342","display_name":"Prevalence of mental disorders","level":3,"score":0.47102150321006775},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.35997825860977173},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.060079485177993774}],"mesh":[{"descriptor_ui":"D001714","descriptor_name":"Bipolar Disorder","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Major Depressive Disorder","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003951","descriptor_name":"Diagnostic Errors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011787","descriptor_name":"Quality of Health Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017050","descriptor_name":"Episode of Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019964","descriptor_name":"Mood Disorders","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:16232009","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16232009","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of managed care","raw_type":"Journal Article"},{"id":"mag:61688430","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16232009","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2809939490","https://openalex.org/W2920330279","https://openalex.org/W2072303383","https://openalex.org/W206224936","https://openalex.org/W26638609","https://openalex.org/W2070158502","https://openalex.org/W4381302628","https://openalex.org/W1969431295","https://openalex.org/W2482580245","https://openalex.org/W2095798253"],"abstract_inverted_index":{"Bipolar":[0],"disorder":[1,13],"is":[2],"both":[3],"prevalent":[4],"and":[5,58,81],"disabling.":[6],"Surveys":[7],"suggest":[8],"that":[9],"patients":[10,27],"with":[11,22],"bipolar":[12],"are":[14],"often":[15,21],"misdiagnosed":[16],"on":[17],"initial":[18],"presentation,":[19],"most":[20],"major":[23],"depressive":[24],"disorder.":[25],"These":[26],"may":[28],"receive":[29],"ineffective":[30],"treatment,":[31],"which,":[32],"in":[33],"some":[34],"cases,":[35],"actually":[36],"worsens":[37],"outcome,":[38],"either":[39],"by":[40,47],"inducing":[41],"manic":[42],"or":[43,46,73,86],"mixed":[44],"states":[45],"increasing":[48],"mood":[49],"cycling.":[50],"Major":[51],"contributors":[52],"to":[53,96],"misdiagnosis":[54],"include":[55],"incomplete":[56],"history":[57],"lack":[59],"of":[60,67,84],"patient":[61],"insight":[62],"as":[63,65,71,88,90],"well":[64,89],"presence":[66],"psychiatric":[68],"comorbidity,":[69],"such":[70],"anxiety":[72],"substance":[74],"use":[75],"disorders.":[76],"Careful":[77],"screening":[78],"for":[79],"current":[80],"past":[82],"symptoms":[83],"mania":[85],"hypomania,":[87],"close":[91],"clinical":[92],"follow-up,":[93],"can":[94],"help":[95],"reduce":[97],"misdiagnosis.":[98]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":13},{"year":2020,"cited_by_count":18},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":12},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}