{"id":"https://openalex.org/W61686322","doi":null,"title":"Exhaled Breath Condensate in Obstructive Lung Diseases : A Methodological study","display_name":"Exhaled Breath Condensate in Obstructive Lung Diseases : A Methodological study","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W61686322","mag":"61686322"},"language":"en","primary_location":{"id":"pmh:oai:DiVA.org:liu-16294","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-16294","pdf_url":null,"source":{"id":"https://openalex.org/S4306400838","display_name":"DiVA (Linkoping University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102134673","host_organization_name":"Link\u00f6ping University","host_organization_lineage":["https://openalex.org/I102134673"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-16294","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002873607","display_name":"Anette Davidsson","orcid":"https://orcid.org/0000-0001-5704-5670","observed_orcids":["https://orcid.org/0000-0001-5704-5670"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Anette Davidsson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5704-5670","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5002873607"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.7070000171661377,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.7070000171661377,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11667","display_name":"Advanced Chemical Sensor Technologies","score":0.1835000067949295,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.0738999992609024,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exhaled-breath-condensate","display_name":"exhaled breath condensate","score":0.9990000128746033},{"id":"https://openalex.org/keywords/airway-inflammation","display_name":"airway inflammation","score":0.8949999809265137},{"id":"https://openalex.org/keywords/allergic-asthma","display_name":"allergic asthma","score":0.8539999723434448},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.9990000128746033},{"id":"https://openalex.org/keywords/noninvasive-biomarkers","display_name":"non-invasive biomarkers","score":0.6980000138282776},{"id":"https://openalex.org/keywords/epithelial-lining-fluid","display_name":"epithelial lining fluid","score":0.7239999771118164},{"id":"https://openalex.org/keywords/chlorine","display_name":"chlorine","score":0.31299999356269836},{"id":"https://openalex.org/keywords/mucus-secretion","display_name":"mucus secretion","score":0.6890000104904175},{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":0.8849999904632568},{"id":"https://openalex.org/keywords/eosinophil-cationic-protein","display_name":"eosinophil cationic protein","score":0.9330000281333923},{"id":"https://openalex.org/keywords/cysteinyl-leukotrienes","display_name":"cysteinyl leukotrienes","score":0.9200000166893005},{"id":"https://openalex.org/keywords/histamine","display_name":"histamine","score":0.8270000219345093},{"id":"https://openalex.org/keywords/lysozyme","display_name":"lysozyme","score":0.9309999942779541},{"id":"https://openalex.org/keywords/saliva","display_name":"saliva","score":0.5040000081062317}],"concepts":[{"id":"https://openalex.org/C2780037985","wikidata":"https://www.wikidata.org/wiki/Q5420171","display_name":"Exhaled breath condensate","level":3,"score":0.620052695274353},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5253012776374817},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5223889946937561},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.41865187883377075},{"id":"https://openalex.org/C43396882","wikidata":"https://www.wikidata.org/wiki/Q2197000","display_name":"Exhalation","level":2,"score":0.41519615054130554},{"id":"https://openalex.org/C39432304","wikidata":"https://www.wikidata.org/wiki/Q188847","display_name":"Environmental science","level":0,"score":0.3362882733345032},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2940845191478729},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.1832226812839508},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.17822027206420898}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:DiVA.org:liu-16294","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-16294","pdf_url":null,"source":{"id":"https://openalex.org/S4306400838","display_name":"DiVA (Linkoping University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102134673","host_organization_name":"Link\u00f6ping University","host_organization_lineage":["https://openalex.org/I102134673"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:61686322","doi":null,"is_oa":false,"landing_page_url":"http://liu.diva-portal.org/smash/get/diva2:133637/POPULARSUMMARY01.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:DiVA.org:liu-16294","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-16294","pdf_url":null,"source":{"id":"https://openalex.org/S4306400838","display_name":"DiVA (Linkoping University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102134673","host_organization_name":"Link\u00f6ping University","host_organization_lineage":["https://openalex.org/I102134673"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":130,"referenced_works":["https://openalex.org/W9223901","https://openalex.org/W174023019","https://openalex.org/W174178599","https://openalex.org/W203060707","https://openalex.org/W292015718","https://openalex.org/W292047634","https://openalex.org/W1589747619","https://openalex.org/W1851970106","https://openalex.org/W1865292579","https://openalex.org/W1893488133","https://openalex.org/W1899229346","https://openalex.org/W1965451386","https://openalex.org/W1965632753","https://openalex.org/W1966679708","https://openalex.org/W1968853064","https://openalex.org/W1969900856","https://openalex.org/W1971821346","https://openalex.org/W1972134778","https://openalex.org/W1973921505","https://openalex.org/W1974431676","https://openalex.org/W1975100479","https://openalex.org/W1976234751","https://openalex.org/W1977541263","https://openalex.org/W1980333734","https://openalex.org/W1987777995","https://openalex.org/W1989935661","https://openalex.org/W1990808812","https://openalex.org/W1995617640","https://openalex.org/W1999226863","https://openalex.org/W2000745053","https://openalex.org/W2000873516","https://openalex.org/W2002273805","https://openalex.org/W2004482750","https://openalex.org/W2005578762","https://openalex.org/W2012770533","https://openalex.org/W2016509364","https://openalex.org/W2016681598","https://openalex.org/W2019099336","https://openalex.org/W2020111980","https://openalex.org/W2021876292","https://openalex.org/W2022351730","https://openalex.org/W2022441811","https://openalex.org/W2022972451","https://openalex.org/W2025059479","https://openalex.org/W2028934802","https://openalex.org/W2031307850","https://openalex.org/W2031768476","https://openalex.org/W2039027028","https://openalex.org/W2043499069","https://openalex.org/W2043673123","https://openalex.org/W2043811030","https://openalex.org/W2045596774","https://openalex.org/W2046416981","https://openalex.org/W2046541211","https://openalex.org/W2050403103","https://openalex.org/W2050774740","https://openalex.org/W2052798406","https://openalex.org/W2053879426","https://openalex.org/W2055157594","https://openalex.org/W2059149560","https://openalex.org/W2060150845","https://openalex.org/W2061748452","https://openalex.org/W2062988784","https://openalex.org/W2063696441","https://openalex.org/W2065348891","https://openalex.org/W2068560260","https://openalex.org/W2069727362","https://openalex.org/W2075206952","https://openalex.org/W2076547090","https://openalex.org/W2077104885","https://openalex.org/W2078377802","https://openalex.org/W2078577501","https://openalex.org/W2081505147","https://openalex.org/W2082393078","https://openalex.org/W2083368461","https://openalex.org/W2084107384","https://openalex.org/W2085856905","https://openalex.org/W2090227927","https://openalex.org/W2095324703","https://openalex.org/W2095566019","https://openalex.org/W2097810244","https://openalex.org/W2099424868","https://openalex.org/W2101117727","https://openalex.org/W2102683270","https://openalex.org/W2105871915","https://openalex.org/W2109292444","https://openalex.org/W2110378267","https://openalex.org/W2110799130","https://openalex.org/W2111126982","https://openalex.org/W2117300976","https://openalex.org/W2118823673","https://openalex.org/W2118909914","https://openalex.org/W2120418918","https://openalex.org/W2121954647","https://openalex.org/W2126010076","https://openalex.org/W2129973295","https://openalex.org/W2130374023","https://openalex.org/W2132855685","https://openalex.org/W2135460444","https://openalex.org/W2135501737","https://openalex.org/W2139626850","https://openalex.org/W2141842086","https://openalex.org/W2141922649","https://openalex.org/W2143573147","https://openalex.org/W2144805836","https://openalex.org/W2147443002","https://openalex.org/W2147630069","https://openalex.org/W2148827247","https://openalex.org/W2152520891","https://openalex.org/W2156107878","https://openalex.org/W2157409103","https://openalex.org/W2157543837","https://openalex.org/W2157650286","https://openalex.org/W2160276128","https://openalex.org/W2160420348","https://openalex.org/W2161693846","https://openalex.org/W2163449193","https://openalex.org/W2166503088","https://openalex.org/W2180680515","https://openalex.org/W2183687504","https://openalex.org/W2224330863","https://openalex.org/W2229360799","https://openalex.org/W2260968094","https://openalex.org/W2338868403","https://openalex.org/W2397689018","https://openalex.org/W2402439738","https://openalex.org/W2406339419","https://openalex.org/W2412191985","https://openalex.org/W2413817680","https://openalex.org/W2416245021"],"related_works":["https://openalex.org/W311861508","https://openalex.org/W2001306447","https://openalex.org/W2075381387","https://openalex.org/W2303541459","https://openalex.org/W2183808364","https://openalex.org/W2152009566","https://openalex.org/W2064188382","https://openalex.org/W2043811030","https://openalex.org/W2115218816","https://openalex.org/W2381992911"],"abstract_inverted_index":{"Asthma":[0],"and":[1,17,31,44,51,59,67,75,95,98,103,107,189,206,229,239,252,330,369,381,394,413,474,478,487,496],"chronic":[2],"obstructive":[3],"pulmonary":[4],"disease":[5],"(COPD)":[6],"are":[7,65,452],"two":[8,201,256,293],"common":[9],"inflammatory":[10,61,100,166,321],"airway":[11,15,85,93,458],"diseases":[12,26],"characterized":[13,397],"by":[14,128,283,312,342,361],"inflammation":[16,41,409],"mucus":[18],"hypersecretion.":[19],"Prediction":[20],"of":[21,24,39,53,84,150,154,165,191,199,212,221,223,254,268,270,285,291,296,303,314,344,399,408,422,432,456,463,468],"the":[22,32,92,111,130,187,200,210,255,292,375,420,423],"outcome":[23],"these":[25],"may":[27,122,143,174],"not":[28],"be":[29,123,145,175,300],"performed":[30],"need":[33,72],"for":[34,82,147],"non-invasive":[35,55,80],"diagnostic":[36,480],"tools":[37],"capable":[38],"identifying":[40],"in":[42,63,125,169,177,195,215,226,244,260,306,337,378,434,450],"asthma":[43,181],"COPD":[45,473,495],"becomes":[46],"therefore":[47],"obvious.":[48],"Validation,":[49],"sensitivity":[50],"specificity":[52],"most":[54],"methods":[56,81],"to":[57,73,132,159,185,208,289,299,365,491],"detect":[58],"monitor":[60],"responses":[62],"airways":[64],"poor":[66],"there":[68],"is":[69,426],"a":[70,134,162,192,286,301,315,442,453],"great":[71],"identify":[74],"standardize":[76],"less":[77],"invasive,":[78],"or":[79,172,182,204,237,274,308,348],"investigation":[83],"inflammation.":[86,459],"Epithelial":[87],"lining":[88],"fluid":[89],"(ELF)":[90],"covers":[91],"surface":[94],"contains":[96],"soluble":[97],"insoluble":[99],"cell":[101,167,322],"products":[102],"plasma":[104],"proteins":[105],"originating":[106],"passively":[108],"transferred":[109,282],"from":[110,472],"underlying":[112],"tissue.":[113],"Airborne":[114],"aerosol":[115],"particles":[116],"containing":[117],"ELF":[118],"saturated":[119],"with":[120,179,233,416],"water":[121],"recovered":[124],"exhaled":[126,138],"air":[127,131],"allowing":[129],"pass":[133],"cold":[135],"surface,":[136],"creating":[137],"breath":[139],"condensate":[140],"(EBC).":[141],"EBC":[142,196,216,307,424,435,451,469],"then":[144],"analysed":[146,336],"various":[148],"components":[149],"interest.":[151],"The":[152,320],"aims":[153],"this":[155],"thesis":[156],"were":[157,258,281,310,335,359,436],"(1)":[158],"explore":[160],"whether":[161],"certain":[163,224],"profile":[164],"markers":[168,323],"EBC,":[170,338],"saliva":[171,309,339,417],"serum":[173,341,488],"identified":[176],"patients":[178,232,476],"allergic":[180,457],"COPD,":[183],"(2)":[184],"evaluate":[186,209],"efficacy":[188],"reproducibility":[190,220,251],"measurable":[193],"marker":[194,302,455],"using":[197,266],"either":[198,290],"condensers":[202,257],"ECoScreen":[203],"RTube":[205],"(3)":[207],"value":[211],"chlorine":[213,297,433,448],"concentrations":[214,431,449],"as":[217,219,374,483],"well":[218],"assessments":[222],"compounds":[225],"EBC.":[227,400],"Material":[228],"methods:":[230],"Thirty-six":[231],"asthma,":[234],"49":[235],"smokers":[236],"ex-smokers":[238],"25":[240],"healthy":[241],"volunteers":[242],"participated":[243],"three":[245],"clinical":[246,366],"studies.":[247],"In":[248],"addition,":[249],"efficacy,":[250],"comparison":[253],"studied":[259],"an":[261],"ex":[262],"vivo":[263],"set":[264],"up":[265],"aerosols":[267],"solutions":[269],"saline,":[271],"myeloperoxidase":[272],"(MPO)":[273],"human":[275],"neutrophil":[276],"lipocalin":[277],"(HNL).":[278],"Aerosol":[279],"boluses":[280],"means":[284,313,343],"servo":[287],"ventilator":[288],"condensers.":[294],"Concentrations":[295],"(presumed":[298],"mucous":[304],"secretion)":[305],"analyzed":[311],"sensitive":[316,454],"coulometric":[317],"technique":[318],"(AOX).":[319],"histamine,":[324],"MPO,":[325],"HNL,":[326],"lysozyme,":[327],"cysteinyl-leukotrienes":[328],"(CysLT)":[329],"eosinophil":[331],"cationic":[332],"protein":[333],"(ECP)":[334],"and/or":[340],"ELISA,":[345],"RIA,":[346],"EIA":[347],"immunochemical":[349],"fluorescence":[350],"methods,":[351],"respectively.":[352],"Lung":[353],"function":[354],"tests,":[355],"including":[356],"diffusion":[357,484],"capacity":[358,485],"measured":[360],"standard":[362],"techniques":[363],"according":[364],"routines.":[367],"Results":[368],"Conclusions:":[370],"Chlorine":[371],"measurements":[372],"served":[373],"main":[376],"tool":[377],"our":[379],"tests":[380],"intra-assay":[382],"variability":[383,412],"<10%":[384],"was":[385],"recorded.":[386],"However,":[387],"flow":[388],"dependency,":[389,391],"temperature":[390],"substance":[392],"dependency":[393,396],"concentration":[395,406],"yields":[398],"Despite":[401,428],"acceptable":[402],"analytical":[403],"precision,":[404],"low":[405],"levels":[407],"markers,":[410],"biological":[411,429],"occasionally":[414],"contamination":[415],"mean":[418],"that":[419,447],"feasibility":[421],"method":[425],"limited.":[427],"variability,":[430],"significantly":[437],"higher":[438],"during":[439],"than":[440],"after":[441],"mild":[443],"pollen":[444],"season,":[445],"suggesting":[446],"A":[460],"vast":[461],"number":[462],"confounding":[464],"factors":[465],"made":[466],"interpretations":[467],"data":[470],"obtained":[471],"non-COPD":[475],"difficult":[477],"traditional":[479],"tools,":[481],"such":[482],"(DLCO)":[486],"lysozyme":[489],"appeared":[490],"best":[492],"discriminate":[493],"between":[494],"non-COPD.":[497]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
