{"id":"https://openalex.org/W6166433","doi":null,"title":"Reduced work of breathing after single lung transplantation for emphysema.","display_name":"Reduced work of breathing after single lung transplantation for emphysema.","publication_year":1995,"publication_date":"1995-01-01","ids":{"openalex":"https://openalex.org/W6166433","mag":"6166433","pmid":"https://pubmed.ncbi.nlm.nih.gov/7727474"},"language":"en","primary_location":{"id":"pmid:7727474","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7727474","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"J P Scott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J P Scott","raw_affiliation_strings":["Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA","Mayo Clinic Rochester-MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"Mayo Clinic Rochester-MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055057150","display_name":"Delmar J. Gillespie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D J Gillespie","raw_affiliation_strings":["Mayo Clinic Rochester-MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Rochester-MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044764406","display_name":"Steve G. Peters","orcid":"https://orcid.org/0000-0001-8438-3261","observed_orcids":["https://orcid.org/0000-0001-8438-3261"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S G Peters","raw_affiliation_strings":["Mayo Clinic Rochester-MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Rochester-MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108363382","display_name":"Ken C. Beck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K C Beck","raw_affiliation_strings":["Mayo Clinic Rochester-MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Rochester-MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060708763","display_name":"David E. Midthun","orcid":"https://orcid.org/0000-0002-4876-059X","observed_orcids":["https://orcid.org/0000-0002-4876-059X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D E Midthun","raw_affiliation_strings":["Mayo Clinic Rochester-MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Rochester-MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108098047","display_name":"John C. McDougall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J C McDougall","raw_affiliation_strings":["Mayo Clinic Rochester-MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Rochester-MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018965634","display_name":"Richard C. Daly","orcid":"https://orcid.org/0009-0005-4266-0722","observed_orcids":["https://orcid.org/0009-0005-4266-0722","https://orcid.org/0000-0001-5865-7708"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R C Daly","raw_affiliation_strings":["Mayo Clinic Rochester-MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Rochester-MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108570476","display_name":"Christoper G.A. McGregor","orcid":"https://orcid.org/0000-0002-2784-5033","observed_orcids":["https://orcid.org/0000-0002-2784-5033"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C G McGregor","raw_affiliation_strings":["Mayo Clinic Rochester-MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic Rochester-MN","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1330342723"],"apc_list":null,"apc_paid":null,"fwci":1.2913,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.79010428,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"14","issue":"1 Pt 1","first_page":"39","last_page":"43"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.009700000286102295,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/single-lung-transplantation","display_name":"single lung transplantation","score":0.9409999847412109},{"id":"https://openalex.org/keywords/emphysema","display_name":"emphysema","score":0.9919999837875366},{"id":"https://openalex.org/keywords/work-of-breathing","display_name":"work of breathing","score":0.828000009059906},{"id":"https://openalex.org/keywords/respiratory-mechanics","display_name":"respiratory mechanics","score":0.972000002861023},{"id":"https://openalex.org/keywords/lung-compliance","display_name":"lung compliance","score":0.6650000214576721},{"id":"https://openalex.org/keywords/pulmonary-resistance","display_name":"pulmonary resistance","score":0.8100000023841858},{"id":"https://openalex.org/keywords/lung-elastic-recoil","display_name":"lung elastic recoil","score":0.871999979019165},{"id":"https://openalex.org/keywords/dyspnea","display_name":"dyspnea","score":0.9139999747276306},{"id":"https://openalex.org/keywords/chronic-bronchitis","display_name":"chronic bronchitis","score":0.7910000085830688},{"id":"https://openalex.org/keywords/postoperative-outcomes","display_name":"postoperative outcomes","score":0.5270000100135803}],"concepts":[{"id":"https://openalex.org/C2777473361","wikidata":"https://www.wikidata.org/wiki/Q5353564","display_name":"Elastic recoil","level":3,"score":0.9166260361671448},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8851104974746704},{"id":"https://openalex.org/C136936797","wikidata":"https://www.wikidata.org/wiki/Q2990558","display_name":"Pulmonary compliance","level":3,"score":0.6493128538131714},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.6354634761810303},{"id":"https://openalex.org/C2781448352","wikidata":"https://www.wikidata.org/wiki/Q1637912","display_name":"Lung transplantation","level":3,"score":0.6240698099136353},{"id":"https://openalex.org/C27101514","wikidata":"https://www.wikidata.org/wiki/Q206120","display_name":"Lung volumes","level":3,"score":0.5287862420082092},{"id":"https://openalex.org/C2992694001","wikidata":"https://www.wikidata.org/wiki/Q173022","display_name":"Chronic bronchitis","level":2,"score":0.5120630860328674},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.4978175163269043},{"id":"https://openalex.org/C2776924770","wikidata":"https://www.wikidata.org/wiki/Q23808249","display_name":"Work of breathing","level":3,"score":0.41881832480430603},{"id":"https://openalex.org/C2781460075","wikidata":"https://www.wikidata.org/wiki/Q1399332","display_name":"Compliance (psychology)","level":2,"score":0.4128116965293884},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.383951872587204},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33378905057907104},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.32909858226776123},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000403","descriptor_name":"Airway Resistance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004417","descriptor_name":"Dyspnea","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008170","descriptor_name":"Lung Compliance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011656","descriptor_name":"Pulmonary Emphysema","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D011656","descriptor_name":"Pulmonary Emphysema","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014939","descriptor_name":"Work of Breathing","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D015656","descriptor_name":"Respiratory Mechanics","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016040","descriptor_name":"Lung Transplantation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017079","descriptor_name":"Exercise Tolerance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:7727474","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7727474","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1373733","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1373733/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Heart Lung Transplant , 14 (1 Pt 1) pp. 39-43. (1995)","raw_type":"Article"},{"id":"mag:6166433","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7727474","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":2,"referenced_works":["https://openalex.org/W2015337422","https://openalex.org/W1875582044"],"related_works":["https://openalex.org/W2244791813","https://openalex.org/W2034865022","https://openalex.org/W1999036780","https://openalex.org/W2350228956","https://openalex.org/W2422538703","https://openalex.org/W137952723","https://openalex.org/W1971596288","https://openalex.org/W2411051392","https://openalex.org/W2079485146","https://openalex.org/W2418397862"],"abstract_inverted_index":{"BACKGROUND:":[0],"Pulmonary":[1],"emphysema,":[2,67],"with":[3,65],"or":[4],"without":[5],"chronic":[6],"bronchitis,":[7],"has":[8],"emerged":[9],"as":[10],"the":[11,37,56,82,93,131,144,267,280,298],"most":[12,300],"common":[13],"indication":[14],"for":[15,92,312],"successful":[16,29],"single":[17,61,263,299,309],"lung":[18,62,102,114,121,125,187,222,240,260,264,289,310],"transplantation.":[19],"Although":[20],"gas":[21],"exchange":[22],"can":[23],"be":[24],"expected":[25],"to":[26,89,129,195,211,229,247,305],"improve":[27],"after":[28,262,308],"transplantation,":[30],"such":[31],"changes":[32],"do":[33],"not":[34],"adequately":[35],"explain":[36],"improvement":[38,270],"in":[39,47,143,259,271,287,293],"dyspnea":[40,307],"experienced":[41],"by":[42,152,172],"these":[43],"patients":[44],"and":[45,96,123,138,161,167,182,238,274],"resulting":[46],"improved":[48,140],"quality":[49],"of":[50,59,68,81,117,134,139,147,154,269,282],"life.":[51],"METHODS:":[52],"We":[53],"prospectively":[54],"studied":[55],"respiratory":[57],"mechanics":[58],"14":[60],"transplantation":[63,265,311],"recipients":[64],"pulmonary":[66,118,204],"whom":[69],"10":[70],"have":[71],"been":[72],"followed":[73],"up":[74],"beyond":[75],"1":[76,175],"year.":[77],"The":[78,257,284],"mean":[79,173],"age":[80],"group":[83],"was":[84,104],"48.8":[85],"years":[86],"(range,":[87],"42":[88],"60":[90],"years)":[91],"seven":[94,97],"men":[95],"women.":[98],"Average":[99],"donor-predicted":[100],"total":[101,113],"capacity":[103],"0.6":[105],"L":[106],"(+0.2":[107],"[standard":[108,176],"error])":[109],"greater":[110],"than":[111],"recipient-predicted":[112],"capacity.":[115],"Comparison":[116],"resistance,":[119],"dynamic":[120],"compliance,":[122],"static":[124,239,288],"compliance":[126,223,241,261,290],"were":[127,150],"taken":[128],"examine":[130],"possible":[132],"role":[133],"reduced":[135,145,275,306],"airways":[136],"resistance":[137,205],"elastic":[141,188,272,294],"recoil":[142,189,273],"work":[146,281],"breathing.":[148,283],"Results":[149],"analyzed":[151],"means":[153],"a":[155],"one-tailed":[156],"paired":[157],"Student":[158],"t":[159],"test":[160],"linear":[162],"regression":[163],"analysis":[164],"(both":[165],"stepwise":[166],"multivariate);":[168],"results":[169],"are":[170],"tabulated":[171],"(+/-":[174,193,197,209,213,227,231,245,249],"error]).":[177],"RESULTS:":[178],"Between":[179],"preoperative":[180],"measurements":[181],"12":[183],"months":[184],"postoperatively,":[185],"maximum":[186],"increased":[190],"from":[191,207,225,243],"8.1":[192],"0.7)":[194,214],"11.3":[196],"1.0)":[198],"cm":[199,215],"H2O,":[200,234,252],"p":[201,218,235,253],"<":[202,219,236,254],"0.01;":[203],"fell":[206,224,242],"8.3":[208],"0.8)":[210],"5.4":[212],"H2O":[216],"sec/L,":[217],"0.01.":[220],"Dynamic":[221],"0.23":[226],"0.04)":[228],"0.12":[230],"0.02)":[232],"L/cm":[233,251],"0.02,":[237],"0.66":[244],"0.13)":[246],"0.22":[248],"0.05)":[250],"0.001.":[255],"CONCLUSIONS:":[256],"decline":[258,286],"reflects":[266],"importance":[268],"chest":[276],"wall":[277],"distention,":[278],"improving":[279],"67%":[285],"(300%":[291],"increase":[292],"recoil)":[295],"is":[296],"probably":[297],"important":[301],"mechanical":[302],"factor":[303],"leading":[304],"emphysema.":[313]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}