{"id":"https://openalex.org/W61322425","doi":null,"title":"Dystrophic cardiac calcinosis in mice: genetic, hormonal, and dietary influences.","display_name":"Dystrophic cardiac calcinosis in mice: genetic, hormonal, and dietary influences.","publication_year":1978,"publication_date":"1978-01-01","ids":{"openalex":"https://openalex.org/W61322425","mag":"61322425","pmid":"https://pubmed.ncbi.nlm.nih.gov/145807","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2018227"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2018227","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2018227","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Pathol","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2018227","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103477152","display_name":"Gordon J. Eaton","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G J Eaton","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113433850","display_name":"R P Custer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R P Custer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"F N Johnson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F N Johnson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5020074288","display_name":"Katharina Stabenow","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K T Stabenow","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2272,"has_fulltext":false,"cited_by_count":87,"citation_normalized_percentile":{"value":0.44476744,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"90","issue":"1","first_page":"173","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12924","display_name":"Dermatological and Skeletal Disorders","score":0.6478999853134155,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12924","display_name":"Dermatological and Skeletal Disorders","score":0.6478999853134155,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.1363999992609024,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.027499999850988388,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inbred-mouse-strains","display_name":"inbred mouse strains","score":0.7400000095367432},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.621999979019165},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8529999852180481},{"id":"https://openalex.org/keywords/mating-status","display_name":"mating status","score":0.6970000267028809},{"id":"https://openalex.org/keywords/progesterone","display_name":"progesterone","score":0.8450000286102295},{"id":"https://openalex.org/keywords/renal-calcinosis","display_name":"renal calcinosis","score":0.8230000138282776},{"id":"https://openalex.org/keywords/pulmonary-calcinosis","display_name":"pulmonary calcinosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/dietary-fat","display_name":"dietary fat","score":0.8759999871253967}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7013464570045471},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.5592249035835266},{"id":"https://openalex.org/C76725341","wikidata":"https://www.wikidata.org/wiki/Q1893126","display_name":"Inbred strain","level":3,"score":0.500917911529541},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4366168975830078},{"id":"https://openalex.org/C2775981168","wikidata":"https://www.wikidata.org/wiki/Q239027","display_name":"Calcinosis","level":3,"score":0.43158864974975586},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4214627742767334},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3951077461242676},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.37885624170303345},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3242855668067932},{"id":"https://openalex.org/C2780309369","wikidata":"https://www.wikidata.org/wiki/Q933382","display_name":"Calcification","level":2,"score":0.2552218437194824},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.18833813071250916},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16805541515350342},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16433995962142944},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002114","descriptor_name":"Calcinosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002114","descriptor_name":"Calcinosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004041","descriptor_name":"Dietary Fats","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006332","descriptor_name":"Cardiomegaly","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D007674","descriptor_name":"Kidney Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009202","descriptor_name":"Cardiomyopathies","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D009202","descriptor_name":"Cardiomyopathies","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011270","descriptor_name":"Pregnancy, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2018227","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2018227","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Pathol","raw_type":"Text"},{"id":"pmid:145807","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/145807","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of pathology","raw_type":"Journal Article"},{"id":"mag:61322425","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/145807","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2018227","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2018227","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Pathol","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1460290523","https://openalex.org/W1515803491","https://openalex.org/W1544017992","https://openalex.org/W1548995119","https://openalex.org/W1568788684","https://openalex.org/W1585003025","https://openalex.org/W1966226199","https://openalex.org/W2012095846","https://openalex.org/W2020007311","https://openalex.org/W2066758060","https://openalex.org/W2173794534"],"related_works":["https://openalex.org/W1971098385","https://openalex.org/W321690692","https://openalex.org/W2811426543","https://openalex.org/W4239764966","https://openalex.org/W86568726","https://openalex.org/W4407211636","https://openalex.org/W2110595422","https://openalex.org/W75427627","https://openalex.org/W2017912935","https://openalex.org/W4389023764"],"abstract_inverted_index":{"Mice":[0],"of":[1,11,25,39,50,70,122,127,133,138,142,161,181,195,203,215,254,264,269,284],"five":[2],"inbred":[3,52],"strains":[4,53,129],"(BALB/c,":[5],"C3H,":[6,231],"C3Hf,":[7,232],"DBA/2,":[8,48],"and":[9,15,23,37,81,86,91,110,117,191,197,208,233,240,244,262],"C57BL/6)":[10],"both":[12,40,71],"sexes,":[13,41],"mated":[14,89,119],"virginal,":[16],"were":[17,44,130,158,185],"examined":[18],"for":[19],"the":[20,51,55,106,111,155,168,174,182,186,216,265,270,285],"incidence,":[21],"severity,":[22],"location":[24,112],"dystrophic":[26],"cardiac":[27,266],"calcinosis":[28,165,220,237],"(DCC)":[29],"at":[30,57],"various":[31],"ages.":[32],"Three":[33],"hybrids,":[34],"B6C3F1,":[35],"C3B6F1,":[36],"CC3F1":[38],"all":[42],"mated,":[43],"likewise":[45],"studied.":[46],"Excepting":[47],"females":[49,126,250],"acquired":[54],"lesion":[56,271],"a":[58,200,257],"much":[59],"earlier":[60],"age":[61],"than":[62],"males;":[63],"DCC":[64,73],"appeared":[65,166],"in":[66,74,88,99,115,150,167,173,230,260],"young":[67],"DBA/s":[68],"mice":[69,76,157,225],"sexes.":[72],"BALB/c":[75,196,224],"was":[77,104,146,178,221,227,238],"almost":[78],"exclusively":[79,113,206],"epicardial":[80],"occurred":[82],"with":[83,93],"equal":[84],"frequency":[85],"severity":[87,263],"males":[90],"females,":[92,120,212],"higher":[94],"incidence":[95,202,261],"but":[96,226],"lesser":[97],"extent":[98],"virginal":[100,125],"females.":[101],"The":[102,193],"occurrence":[103],"highest,":[105],"degree":[107],"most":[108],"severe,":[109],"myocardial":[114,207,274],"C3H":[116,198,217,243,249],"C3Hf":[118,151,245],"irrespective":[121],"parity,":[123],"whereas":[124],"these":[128],"entirely":[131],"free":[132],"disease":[134],"even":[135],"after":[136],"administration":[137],"exogenous":[139],"progesterone.":[140],"Involvement":[141],"males,":[143],"also":[144],"myocardial,":[145],"relatively":[147],"minimal,":[148],"especially":[149],"mice.":[152],"Over":[153],"half":[154],"DBA/2":[156,234],"affected,":[159],"regardless":[160],"sex":[162],"or":[163],"mating;":[164],"epicardium":[169],"and/or":[170],"myocardium,":[171],"predominantly":[172],"myocardium.":[175],"Strain":[176],"C57BL/6":[177],"completely":[179],"devoid":[180],"lesion,":[183],"as":[184,281],"two":[187],"hybrids":[188],"thereof,":[189],"B6C3F1":[190],"C3B6F1.":[192],"hybrid":[194],"showed":[199,256],"high":[201],"minimal":[204],"involvement,":[205],"limited":[209,241],"to":[210,242,276],"breeding":[211],"indicating":[213],"dominance":[214],"gene(s).":[218],"Renal":[219],"uncommon":[222],"among":[223],"frequently":[228],"found":[229],"strains.":[235],"Pulmonary":[236],"rare":[239],"female":[246],"breeders.":[247],"Mated":[248],"fed":[251],"increasing":[252],"amounts":[253],"fat":[255],"concomitant":[258],"rise":[259],"lesions.":[267],"Progression":[268],"from":[272],"necrotic":[273],"fibers":[275],"fibrocalcific":[277],"masses":[278],"is":[279,282],"illustrated,":[280],"formation":[283],"renal":[286],"deposits.":[287]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}