{"id":"https://openalex.org/W612875974","doi":null,"title":"Etude structure-fonction de l'aminopeptidase a par mutagenese dirigee ; contribution a l'analyse moleculaire du site actif","display_name":"Etude structure-fonction de l'aminopeptidase a par mutagenese dirigee ; contribution a l'analyse moleculaire du site actif","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W612875974","mag":"612875974"},"language":"fr","primary_location":{"id":"mag:612875974","doi":null,"is_oa":false,"landing_page_url":"http://www.theses.fr/1997PA11T017","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035706117","display_name":"Gilles Vazeux","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Gilles Vazeux","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5035706117"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.9154999852180481,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.9154999852180481,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.04349999874830246,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.029400000348687172,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aminopeptidase-a","display_name":"aminopeptidase A","score":0.9929999709129333},{"id":"https://openalex.org/keywords/structure-function-relationship","display_name":"structure-function relationship","score":0.7850000262260437},{"id":"https://openalex.org/keywords/site-directed-mutagenesis","display_name":"site-directed mutagenesis","score":0.8730000257492065},{"id":"https://openalex.org/keywords/active-site","display_name":"active site","score":0.9359999895095825},{"id":"https://openalex.org/keywords/molecular-analysis","display_name":"molecular analysis","score":0.7120000123977661},{"id":"https://openalex.org/keywords/enzyme-active-site","display_name":"enzyme active site","score":0.7360000014305115}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6619491577148438},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.35013335943222046}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:612875974","doi":null,"is_oa":false,"landing_page_url":"http://www.theses.fr/1997PA11T017","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W633399342","https://openalex.org/W7015493566","https://openalex.org/W7065344298","https://openalex.org/W7030321888","https://openalex.org/W7422153","https://openalex.org/W2318571213","https://openalex.org/W2977654705","https://openalex.org/W207909462","https://openalex.org/W7036093957","https://openalex.org/W109364509"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}