{"id":"https://openalex.org/W609932591","doi":null,"title":"Training is Medicine; Endurance and Strength Training in Coronary Artery Disease and Health","display_name":"Training is Medicine; Endurance and Strength Training in Coronary Artery Disease and Health","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W609932591","mag":"609932591"},"language":"en","primary_location":{"id":"pmh:oai:ntnuopen.ntnu.no:11250/264630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11250/264630","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/11250/264630","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084225927","display_name":"Trine Karlsen","orcid":"https://orcid.org/0000-0002-1410-7728","observed_orcids":["https://orcid.org/0000-0002-1410-7728"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Trine Karlsen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1410-7728","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5084225927"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10157","display_name":"Sports Performance and Training","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11922","display_name":"Cardiovascular Effects of Exercise","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-intensity-interval-training","display_name":"high-intensity interval training","score":0.847000002861023},{"id":"https://openalex.org/keywords/endurance-training","display_name":"endurance training","score":0.7039999961853027},{"id":"https://openalex.org/keywords/resistance-training","display_name":"resistance training","score":0.746999979019165},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":0.9829999804496765},{"id":"https://openalex.org/keywords/vo2max","display_name":"VO2max","score":0.9419999718666077},{"id":"https://openalex.org/keywords/stroke-volume","display_name":"stroke volume","score":0.7879999876022339},{"id":"https://openalex.org/keywords/left-ventricular-ejection-fraction","display_name":"left ventricular ejection fraction","score":0.9739999771118164},{"id":"https://openalex.org/keywords/hyperoxia","display_name":"hyperoxia","score":0.6470000147819519},{"id":"https://openalex.org/keywords/rate-of-force-development","display_name":"rate of force development","score":0.7580000162124634},{"id":"https://openalex.org/keywords/muscle-strength","display_name":"muscle strength","score":0.7170000076293945},{"id":"https://openalex.org/keywords/leg-press","display_name":"leg press","score":0.5889999866485596},{"id":"https://openalex.org/keywords/myocardial-contractility","display_name":"cardiac contractility","score":0.6700000166893005}],"concepts":[{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.6833439469337463},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5718730688095093},{"id":"https://openalex.org/C93038891","wikidata":"https://www.wikidata.org/wiki/Q1061524","display_name":"Intensity (physics)","level":2,"score":0.5563927292823792},{"id":"https://openalex.org/C2777973682","wikidata":"https://www.wikidata.org/wiki/Q1558681","display_name":"Interval training","level":2,"score":0.5497418642044067},{"id":"https://openalex.org/C196310339","wikidata":"https://www.wikidata.org/wiki/Q60354","display_name":"VO2 max","level":4,"score":0.5490397214889526},{"id":"https://openalex.org/C2777211547","wikidata":"https://www.wikidata.org/wiki/Q17141490","display_name":"Training (meteorology)","level":2,"score":0.5118417143821716},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5059286952018738},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4679132103919983},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.45898520946502686},{"id":"https://openalex.org/C103038586","wikidata":"https://www.wikidata.org/wiki/Q1152037","display_name":"Aerobic exercise","level":2,"score":0.4552331268787384},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.4409292936325073},{"id":"https://openalex.org/C123550912","wikidata":"https://www.wikidata.org/wiki/Q12834857","display_name":"Strength training","level":2,"score":0.42054080963134766},{"id":"https://openalex.org/C2781444488","wikidata":"https://www.wikidata.org/wiki/Q2756206","display_name":"High-intensity interval training","level":2,"score":0.4172626733779907},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.10788190364837646},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.07185837626457214},{"id":"https://openalex.org/C153294291","wikidata":"https://www.wikidata.org/wiki/Q25261","display_name":"Meteorology","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:ntnuopen.ntnu.no:11250/264630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11250/264630","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:609932591","doi":null,"is_oa":false,"landing_page_url":"https://europepmc.org/article/ETH/7538","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:ntnuopen.ntnu.no:11250/264630","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11250/264630","pdf_url":null,"source":{"id":"https://openalex.org/S7407064446","display_name":"NORA - Norwegian Open Research Archives","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":207,"referenced_works":["https://openalex.org/W3510465","https://openalex.org/W90427597","https://openalex.org/W143056972","https://openalex.org/W173084611","https://openalex.org/W181295209","https://openalex.org/W279836321","https://openalex.org/W435770573","https://openalex.org/W607100890","https://openalex.org/W1482115950","https://openalex.org/W1506251539","https://openalex.org/W1549714893","https://openalex.org/W1556303558","https://openalex.org/W1565566980","https://openalex.org/W1697389429","https://openalex.org/W1750872931","https://openalex.org/W1815472814","https://openalex.org/W1899016472","https://openalex.org/W1926550845","https://openalex.org/W1931991697","https://openalex.org/W1939789398","https://openalex.org/W1954120324","https://openalex.org/W1956531608","https://openalex.org/W1963037397","https://openalex.org/W1963089161","https://openalex.org/W1970430928","https://openalex.org/W1971474283","https://openalex.org/W1975613395","https://openalex.org/W1976771488","https://openalex.org/W1977427250","https://openalex.org/W1977599988","https://openalex.org/W1978196408","https://openalex.org/W1978495288","https://openalex.org/W1980895517","https://openalex.org/W1981042436","https://openalex.org/W1983076149","https://openalex.org/W1983620214","https://openalex.org/W1984731050","https://openalex.org/W1984824087","https://openalex.org/W1985405754","https://openalex.org/W1985833525","https://openalex.org/W1989001142","https://openalex.org/W1989477512","https://openalex.org/W1989889546","https://openalex.org/W1990652726","https://openalex.org/W1992582458","https://openalex.org/W1994867738","https://openalex.org/W1994871067","https://openalex.org/W1995344294","https://openalex.org/W1997704726","https://openalex.org/W1998623970","https://openalex.org/W2000364699","https://openalex.org/W2001206974","https://openalex.org/W2001378012","https://openalex.org/W2003838702","https://openalex.org/W2005784582","https://openalex.org/W2005975960","https://openalex.org/W2009180834","https://openalex.org/W2010802005","https://openalex.org/W2011086865","https://openalex.org/W2013444603","https://openalex.org/W2015766228","https://openalex.org/W2016054965","https://openalex.org/W2017541770","https://openalex.org/W2018567279","https://openalex.org/W2018696684","https://openalex.org/W2021952948","https://openalex.org/W2022894974","https://openalex.org/W2023865249","https://openalex.org/W2025401490","https://openalex.org/W2026391463","https://openalex.org/W2027000781","https://openalex.org/W2028621734","https://openalex.org/W2029473862","https://openalex.org/W2030841086","https://openalex.org/W2033328575","https://openalex.org/W2037814771","https://openalex.org/W2038580193","https://openalex.org/W2039603591","https://openalex.org/W2040165855","https://openalex.org/W2041672171","https://openalex.org/W2042848761","https://openalex.org/W2043076813","https://openalex.org/W2045459948","https://openalex.org/W2045655456","https://openalex.org/W2046259609","https://openalex.org/W2046484874","https://openalex.org/W2046531010","https://openalex.org/W2050974632","https://openalex.org/W2051092651","https://openalex.org/W2052303409","https://openalex.org/W2055131822","https://openalex.org/W2055737724","https://openalex.org/W2055869123","https://openalex.org/W2057056778","https://openalex.org/W2057778639","https://openalex.org/W2059938268","https://openalex.org/W2060065519","https://openalex.org/W2061302968","https://openalex.org/W2061974967","https://openalex.org/W2063636901","https://openalex.org/W2064594992","https://openalex.org/W2066381010","https://openalex.org/W2067037651","https://openalex.org/W2067106651","https://openalex.org/W2067447570","https://openalex.org/W2067631284","https://openalex.org/W2070451910","https://openalex.org/W2070655797","https://openalex.org/W2072399660","https://openalex.org/W2073397713","https://openalex.org/W2074023979","https://openalex.org/W2075226747","https://openalex.org/W2078181707","https://openalex.org/W2080135920","https://openalex.org/W2083734022","https://openalex.org/W2084562326","https://openalex.org/W2088639163","https://openalex.org/W2090907451","https://openalex.org/W2091125809","https://openalex.org/W2091591758","https://openalex.org/W2091845882","https://openalex.org/W2093406992","https://openalex.org/W2093833638","https://openalex.org/W2094000188","https://openalex.org/W2095197022","https://openalex.org/W2095423498","https://openalex.org/W2096190290","https://openalex.org/W2096194985","https://openalex.org/W2098522853","https://openalex.org/W2101047147","https://openalex.org/W2103057666","https://openalex.org/W2104635555","https://openalex.org/W2104689152","https://openalex.org/W2107258674","https://openalex.org/W2109352669","https://openalex.org/W2109713827","https://openalex.org/W2110289737","https://openalex.org/W2111577355","https://openalex.org/W2111813234","https://openalex.org/W2112964789","https://openalex.org/W2113991276","https://openalex.org/W2114538425","https://openalex.org/W2116631824","https://openalex.org/W2117855475","https://openalex.org/W2119150168","https://openalex.org/W2119627241","https://openalex.org/W2120222308","https://openalex.org/W2121350517","https://openalex.org/W2121942575","https://openalex.org/W2122789138","https://openalex.org/W2122844888","https://openalex.org/W2123355984","https://openalex.org/W2124600005","https://openalex.org/W2125349482","https://openalex.org/W2125391099","https://openalex.org/W2125646886","https://openalex.org/W2125702693","https://openalex.org/W2126092329","https://openalex.org/W2127367556","https://openalex.org/W2128743865","https://openalex.org/W2129512446","https://openalex.org/W2130844180","https://openalex.org/W2132706092","https://openalex.org/W2135155386","https://openalex.org/W2135925527","https://openalex.org/W2136315725","https://openalex.org/W2138743968","https://openalex.org/W2141191517","https://openalex.org/W2142115426","https://openalex.org/W2146364031","https://openalex.org/W2147449035","https://openalex.org/W2151607481","https://openalex.org/W2156244896","https://openalex.org/W2156321091","https://openalex.org/W2159087408","https://openalex.org/W2161423875","https://openalex.org/W2161991821","https://openalex.org/W2162159245","https://openalex.org/W2165012244","https://openalex.org/W2166058152","https://openalex.org/W2166198581","https://openalex.org/W2169678233","https://openalex.org/W2171082437","https://openalex.org/W2171601214","https://openalex.org/W2171731864","https://openalex.org/W2172369052","https://openalex.org/W2173150146","https://openalex.org/W2175847409","https://openalex.org/W2177534860","https://openalex.org/W2183089531","https://openalex.org/W2205573324","https://openalex.org/W2323692584","https://openalex.org/W2326400675","https://openalex.org/W2326572543","https://openalex.org/W2400644602","https://openalex.org/W2402964687","https://openalex.org/W2418874078","https://openalex.org/W2419019517","https://openalex.org/W2422738685","https://openalex.org/W2436666182","https://openalex.org/W2727252250","https://openalex.org/W3018034337","https://openalex.org/W3211239976","https://openalex.org/W4295800304","https://openalex.org/W4297791496","https://openalex.org/W4299683482","https://openalex.org/W4300020604"],"related_works":["https://openalex.org/W592282157","https://openalex.org/W2144741307","https://openalex.org/W2007234178","https://openalex.org/W2132706092","https://openalex.org/W2108603081","https://openalex.org/W2346411721","https://openalex.org/W2917946411","https://openalex.org/W1980992177","https://openalex.org/W2162159245","https://openalex.org/W2747916207"],"abstract_inverted_index":{"High":[0,132],"aerobic":[1,43,53,105,133,164,181],"intensity":[2,21,44,54,106,134,165,182],"interval":[3,45,107,135,166,183],"training":[4,16,46,56,63,108,136,167,184,191,205,250],"at":[5,64,109,168],"90-95%":[6],"of":[7,68,74,111,170,246,278,300,317],"maximal":[8,24,69,75,80,89,271,275],"heart":[9,70,76,113,172],"rate":[10,114,173,277,299],"is":[11,49,57,226],"more":[12,59],"effective":[13,60],"than":[14,61],"continuous":[15],"with":[17,93,212,267],"low":[18],"to":[19,37,153,198,214,314],"moderate":[20,215],"in":[22,27,41,78,88,95,127,147,185,206,238,256,285],"improving":[23,79],"oxygen":[25,81,90,236],"uptake":[26,82,91],"healthy":[28,318],"young":[29],"men.":[30],"Maximal":[31],"cardiac":[32,84,118,139],"stroke":[33,85,96,119,140,196],"volume":[34,120,141,197],"was":[35],"improved":[36,305],"a":[38,99,291],"similar":[39],"extent":[40,201],"high":[42,52,163,180],"only.":[47],"It":[48],"concluded":[50,227],"that":[51,228],"endurance":[55],"significantly":[58,115],"isocaloric":[62],"lactate":[65],"threshold":[66],"(85%":[67],"rate)":[71],"or":[72],"70%":[73],"rate,":[77],"and":[83,121,142,157,194,242,270,281,298],"volume.":[86],"Improvements":[87],"corresponded":[92],"changes":[94],"volume,":[97],"indicating":[98],"close":[100],"link":[101],"between":[102],"the":[103,199,229,310,315],"two.\\n\\nHigh":[104],"85-95%":[110,169],"peak":[112,117,138,171,195],"improves":[116,137,192,274],"resting":[122],"left":[123,143,159],"ventricular":[124,144,160],"ejection":[125,145],"fraction":[126,146],"coronary":[128,148,186,208,216,230,286],"artery":[129,149,187,209,231,287],"disease":[130,150,188,210,232,288],"patients.":[131,189],"patients":[151,211,233,289,311],"due":[152],"increased":[154],"myocardial":[155],"contractility":[156],"enhanced":[158],"systolic":[161],"performance.\\n\\nHyperoxic":[162],"gave":[174],"no":[175,254],"additional":[176],"effect":[177],"over":[178],"normoxic":[179],"Hyperoxic":[190,249],"VO2peak":[193,224,239],"same":[200],"as":[202],"ambient":[203],"air":[204],"stable":[207],"mild":[213],"ischemia.":[217],"As":[218],"acute":[219],"hyperoxia":[220],"did":[221],"not":[222],"increase":[223,255],"it":[225],"showed":[234],"peripheral":[235],"limitations":[237],"both":[240],"before":[241],"after":[243],"10":[244],"weeks":[245],"hyperoxic":[247],"training.":[248],"may":[251],"thereby":[252],"represent":[253],"cardiovascular":[257],"shear":[258],"stress.\\n\\nMaximal":[259],"leg":[260],"press":[261],"exercise":[262,293],"focusing":[263],"on":[264],"few":[265],"repetitions":[266],"heavy":[268],"loads":[269],"concentric":[272],"contractions":[273],"strength,":[276],"force":[279,301],"developments":[280],"walking":[282,306],"mechanical":[283,307],"efficiency":[284,308,313],"through":[290],"minimal":[292],"effort.":[294],"Improved":[295],"muscular":[296],"strength":[297],"development":[302],"translates":[303],"into":[304],"returning":[309],"work":[312],"levels":[316],"age":[319],"matched":[320],"subjects.":[321]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
