{"id":"https://openalex.org/W60750783","doi":null,"title":"Evaluation of target organ damage in arterial hypertension: which role for qualitative funduscopic examination?","display_name":"Evaluation of target organ damage in arterial hypertension: which role for qualitative funduscopic examination?","publication_year":2001,"publication_date":"2001-09-01","ids":{"openalex":"https://openalex.org/W60750783","mag":"60750783","pmid":"https://pubmed.ncbi.nlm.nih.gov/11666100"},"language":"en","primary_location":{"id":"pmid:11666100","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11666100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Italian heart journal : official journal of the Italian Federation of Cardiology","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073823172","display_name":"Cesare Cuspidi","orcid":"https://orcid.org/0000-0002-7689-478X","observed_orcids":["https://orcid.org/0000-0002-7689-478X"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I2803066834","display_name":"Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico","ror":"https://ror.org/016zn0y21","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I189158943","https://openalex.org/I2803066834","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"C Cuspidi","raw_affiliation_strings":["Institute of Internal Medicine, Centro di Fisiologia Clinica e Ipertensione, Ospedale Maggiore Policlinico IRCCS, University of Milan, Italy. dhipertensione@libero.it"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Internal Medicine, Centro di Fisiologia Clinica e Ipertensione, Ospedale Maggiore Policlinico IRCCS, University of Milan, Italy. dhipertensione@libero.it","institution_ids":["https://openalex.org/I189158943","https://openalex.org/I2803066834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008789869","display_name":"Giuseppe Macca","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Macca","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112072089","display_name":"M Salerno","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Salerno","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048630042","display_name":"L Michev","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Michev","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040834976","display_name":"Veronica Fusi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Fusi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060319676","display_name":"B Severgnini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Severgnini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"C Corti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Corti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107836651","display_name":"Stefano Meani","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Meani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013663765","display_name":"Fabio Magrini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Magrini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5042107498","display_name":"Alberto Zanchetti","orcid":"https://orcid.org/0000-0003-4796-7959","observed_orcids":["https://orcid.org/0000-0003-4796-7959"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Zanchetti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.0496,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.87045008,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"2","issue":"9","first_page":"702","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9545999765396118,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.016699999570846558,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.010700000450015068,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/target-organ-damage","display_name":"target organ damage","score":0.8939999938011169},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.8180000185966492},{"id":"https://openalex.org/keywords/essential-hypertension","display_name":"essential hypertension","score":0.9129999876022339},{"id":"https://openalex.org/keywords/hypertensive-retinopathy","display_name":"hypertensive retinopathy","score":0.9340000152587891},{"id":"https://openalex.org/keywords/retinal-abnormalities","display_name":"retinal abnormalities","score":0.703000009059906},{"id":"https://openalex.org/keywords/fundus-examination","display_name":"fundus examination","score":0.7630000114440918},{"id":"https://openalex.org/keywords/left-ventricular-hypertrophy","display_name":"left ventricular hypertrophy","score":0.9800000190734863},{"id":"https://openalex.org/keywords/carotid-plaque","display_name":"carotid plaque","score":0.8650000095367432},{"id":"https://openalex.org/keywords/microalbuminuria","display_name":"microalbuminuria","score":0.9760000109672546},{"id":"https://openalex.org/keywords/eccentric-left-ventricular-hypertrophy","display_name":"eccentric left ventricular hypertrophy","score":0.75},{"id":"https://openalex.org/keywords/hypertensive-vascular-disease","display_name":"hypertensive vascular disease","score":0.7739999890327454}],"concepts":[{"id":"https://openalex.org/C2781203188","wikidata":"https://www.wikidata.org/wiki/Q1676817","display_name":"Microalbuminuria","level":3,"score":0.9635571837425232},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8988214135169983},{"id":"https://openalex.org/C2776002628","wikidata":"https://www.wikidata.org/wiki/Q1628627","display_name":"Left ventricular hypertrophy","level":3,"score":0.8089041709899902},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6103761196136475},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6084388494491577},{"id":"https://openalex.org/C2776004912","wikidata":"https://www.wikidata.org/wiki/Q425811","display_name":"Hypertensive retinopathy","level":4,"score":0.5781227946281433},{"id":"https://openalex.org/C2776761947","wikidata":"https://www.wikidata.org/wiki/Q5045548","display_name":"Carotid ultrasonography","level":3,"score":0.5240842700004578},{"id":"https://openalex.org/C2776174234","wikidata":"https://www.wikidata.org/wiki/Q974792","display_name":"Albuminuria","level":3,"score":0.46464109420776367},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4427644908428192},{"id":"https://openalex.org/C2778532077","wikidata":"https://www.wikidata.org/wiki/Q5375888","display_name":"End organ damage","level":3,"score":0.4312777519226074},{"id":"https://openalex.org/C2778313320","wikidata":"https://www.wikidata.org/wiki/Q550455","display_name":"Retinopathy","level":3,"score":0.3247743248939514},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.3131592273712158},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.2713627517223358},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1746578812599182},{"id":"https://openalex.org/C2987047532","wikidata":"https://www.wikidata.org/wiki/Q214275","display_name":"Carotid arteries","level":2,"score":0.08907020092010498},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000419","descriptor_name":"Albuminuria","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D000419","descriptor_name":"Albuminuria","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D002339","descriptor_name":"Carotid Arteries","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D002340","descriptor_name":"Carotid Artery Diseases","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D002340","descriptor_name":"Carotid Artery Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012164","descriptor_name":"Retinal Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012164","descriptor_name":"Retinal Diseases","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013223","descriptor_name":"Statistics as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017379","descriptor_name":"Hypertrophy, Left Ventricular","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D017379","descriptor_name":"Hypertrophy, Left Ventricular","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D017539","descriptor_name":"Tunica Intima","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D019721","descriptor_name":"Ophthalmoscopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:11666100","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11666100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Italian heart journal : official journal of the Italian Federation of Cardiology","raw_type":"Comparative Study"},{"id":"pmh:oai:boa.unimib.it:10281/83092","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10281/83092","pdf_url":null,"source":{"id":"https://openalex.org/S4306401259","display_name":"BOA (University of Milano-Bicocca)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:60750783","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11666100","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2068579932","https://openalex.org/W2118395770","https://openalex.org/W7221685596","https://openalex.org/W1986215457","https://openalex.org/W2114493622","https://openalex.org/W2505685526","https://openalex.org/W7222301393","https://openalex.org/W2169076437","https://openalex.org/W3037860308","https://openalex.org/W2562664112"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1],"objective":[2],"of":[3,11,14,33,46,140,210,247,257,286,318,333],"this":[4,303],"study":[5],"was":[6,145,184,196,224,229],"to":[7,81,92,101,125],"compare":[8],"the":[9,78,88,102,126,141,197,225,235,245,274,319,327,330],"prevalence":[10,256],"quantitative":[12,331],"markers":[13,246],"target":[15,95,211,287,334],"organ":[16,96,212,288,335],"damage,":[17,97,213,252,289],"such":[18],"as":[19,147,160,186,232,234,271,282],"echocardiographically":[20],"documented":[21],"left":[22,162],"ventricular":[23,163],"hypertrophy":[24],"(LVH),":[25],"carotid":[26,118,182,216],"structural":[27],"changes":[28,121],"and":[29,59,116,129,154,173,228,238,250,261,316],"microalbuminuria":[30,239],"with":[31,48,244],"that":[32,308],"retinal":[34,258,278,309],"abnormalities":[35,259,279,310],"detected":[36],"by":[37,133,215,273,297],"qualitative":[38],"funduscopic":[39,313],"examination":[40],"in":[41,87,171,179,267,312],"a":[42,148,161,187,283],"large":[43],"selected":[44],"population":[45],"patients":[47,65,293],"essential":[49],"hypertension.":[50],"METHODS:":[51],"Eight":[52],"hundred":[53],"consecutive":[54],"untreated":[55],"(n":[56,61],"=":[57,62,168,176],"232)":[58],"treated":[60],"568)":[63],"hypertensive":[64,298],"(386":[66],"men,":[67],"414":[68],"women,":[69],"mean":[70],"age":[71],"52.7":[72],"+/-":[73],"11.8":[74],"years)":[75],"referred":[76],"for":[77,94,112,329],"first":[79],"time":[80],"our":[82,268],"out-patient":[83],"clinic":[84],"were":[85,99,122,265,280],"included":[86,311],"study.":[89],"In":[90],"order":[91],"search":[93],"they":[98],"submitted":[100],"following":[103],"procedures:":[104],"1)":[105],"amydriatic":[106],"retinography,":[107],"2)":[108],"24-hour":[109],"urine":[110],"collection":[111],"microalbuminuria,":[113],"3)":[114],"echocardiography,":[115],"4)":[117],"ultrasonography.":[119],"Retinal":[120],"evaluated":[123],"according":[124],"Keith,":[127],"Wagener":[128],"Barker":[130],"(KWB)":[131],"classification":[132,321],"two":[134],"physicians,":[135],"who":[136],"had":[137],"no":[138],"knowledge":[139],"patients'":[142],"characteristics.":[143],"Microalbuminuria":[144],"defined":[146,185],"urinary":[149],"albumin":[150],"excretion":[151],">":[152,166,174,190],"30":[153],"<":[155,207],"300":[156],"mg/24":[157],"hours,":[158],"LVH":[159,219,223],"mass":[164],"index":[165],"or":[167,175],"134":[169],"g/m2":[170,178],"men":[172],"110":[177],"women;":[180],"finally":[181],"plaque":[183],"focal":[188],"thickening":[189],"1.3":[191],"mm.":[192],"RESULTS:":[193],"Hypertensive":[194],"retinopathy":[195],"most":[198],"frequent":[199,233],"(KWB":[200],"grade":[201],"I":[202,315],"46%,":[203],"II":[204,317],"32%,":[205],"III-IV":[206],"2%)":[208],"marker":[209,285],"followed":[214],"plaques":[217],"(43%),":[218],"(22":[220],"%,":[221],"eccentric":[222],"prevalent":[226],"type":[227],"1.8":[230],"times":[231],"concentric":[236],"one)":[237],"(14%).":[240],"CONCLUSIONS:":[241],"At":[242],"variance":[243],"cardiac,":[248],"macrovascular":[249],"renal":[251],"an":[253],"extremely":[254],"high":[255],"(narrowings":[260],"initial":[262],"arterio-venous":[263],"crossings)":[264],"found":[266],"population.":[269],"If,":[270],"suggested":[272,307],"WHO/ISH":[275],"guidelines,":[276],"these":[277],"considered":[281,325],"reliable":[284],"then":[290],"almost":[291],"all":[292],"would":[294],"be":[295,324],"affected":[296],"vascular":[299],"disease.":[300],"Based":[301],"on":[302],"evidence":[304],"it":[305],"is":[306],"grades":[314],"KWB":[320],"should":[322],"not":[323],"among":[326],"criteria":[328],"detection":[332],"damage.":[336]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}