{"id":"https://openalex.org/W60356693","doi":"https://doi.org/10.1016/b978-0-12-401650-7.50016-8","title":"ACTIVATION OF AND TOLERANCE INDUCTION IN DNP-SPECIFIC B CELLS: ANALYSIS WITH THREE DISTINCT DNP-CARRIER CONJUGATES","display_name":"ACTIVATION OF AND TOLERANCE INDUCTION IN DNP-SPECIFIC B CELLS: ANALYSIS WITH THREE DISTINCT DNP-CARRIER CONJUGATES","publication_year":1974,"publication_date":"1974-01-01","ids":{"openalex":"https://openalex.org/W60356693","doi":"https://doi.org/10.1016/b978-0-12-401650-7.50016-8","mag":"60356693"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-12-401650-7.50016-8","doi":"https://doi.org/10.1016/b978-0-12-401650-7.50016-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-401650-7.50016-8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological Tolerance","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4292921868","display_name":"Immunological Tolerance"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110180932","display_name":"William E. Paul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William E. Paul","raw_affiliation_strings":["Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, Maryland 20014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, Maryland 20014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037959289","display_name":"Michael Karpf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Karpf","raw_affiliation_strings":["Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, Maryland 20014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, Maryland 20014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019314608","display_name":"Donald E. Mosier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald E. Mosier","raw_affiliation_strings":["Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, Maryland 20014"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health Bethesda, Maryland 20014","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8555,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.80275229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"141","last_page":"158"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/b-cell-activation","display_name":"B cell activation","score":0.8920000195503235},{"id":"https://openalex.org/keywords/b-cell-tolerance","display_name":"B cell tolerance","score":0.7519999742507935},{"id":"https://openalex.org/keywords/dnp-ficoll","display_name":"DNP-Ficoll","score":0.7110000252723694},{"id":"https://openalex.org/keywords/t-cell-independent-activation","display_name":"T cell-independent activation","score":0.7250000238418579},{"id":"https://openalex.org/keywords/b-cell-proliferation","display_name":"B cell proliferation","score":0.7480000257492065},{"id":"https://openalex.org/keywords/antibody-secretion","display_name":"immunoglobulin secretion","score":0.8220000267028809}],"concepts":[{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6610381603240967},{"id":"https://openalex.org/C2778177356","wikidata":"https://www.wikidata.org/wiki/Q19903955","display_name":"Dinitrophenyl","level":3,"score":0.48655977845191956},{"id":"https://openalex.org/C67662055","wikidata":"https://www.wikidata.org/wiki/Q1047791","display_name":"Antigen-presenting cell","level":4,"score":0.47360682487487793},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.47217267751693726},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.46806517243385315},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.4608878791332245},{"id":"https://openalex.org/C2778453870","wikidata":"https://www.wikidata.org/wiki/Q188930","display_name":"B cell","level":3,"score":0.45634588599205017},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4142935872077942},{"id":"https://openalex.org/C39347974","wikidata":"https://www.wikidata.org/wiki/Q21135811","display_name":"CD40","level":4,"score":0.4125927984714508},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4069664776325226},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3961167633533478},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.287767231464386},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2848018705844879},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.201665461063385},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.18183046579360962},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.17043530941009521}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-12-401650-7.50016-8","doi":"https://doi.org/10.1016/b978-0-12-401650-7.50016-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-401650-7.50016-8","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunological Tolerance","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1503274940","https://openalex.org/W1546653752","https://openalex.org/W1652473508","https://openalex.org/W1975649472","https://openalex.org/W2027296760","https://openalex.org/W2030698538","https://openalex.org/W2033409350","https://openalex.org/W2049501288","https://openalex.org/W2057572787","https://openalex.org/W2063856745","https://openalex.org/W2066722240","https://openalex.org/W2132255277","https://openalex.org/W2133164292","https://openalex.org/W2144816860","https://openalex.org/W4313309946"],"related_works":["https://openalex.org/W2038148088","https://openalex.org/W2152256497","https://openalex.org/W2062940475","https://openalex.org/W2155536590","https://openalex.org/W2440111173","https://openalex.org/W1970255342","https://openalex.org/W2144816860","https://openalex.org/W1978356225","https://openalex.org/W1550278711","https://openalex.org/W2085173629"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
