{"id":"https://openalex.org/W60212219","doi":null,"title":"Experimentally induced swine dysentery","display_name":"Experimentally induced swine dysentery","publication_year":2007,"publication_date":"2007-05-01","ids":{"openalex":"https://openalex.org/W60212219","mag":"60212219"},"language":"en","primary_location":{"id":"pmh:oai:pub.epsilon.slu.se:1438","doi":null,"is_oa":true,"landing_page_url":"https://pub.epsilon.slu.se/1438/1/200716_Thesis.pdf","pdf_url":"https://pub.epsilon.slu.se/1438/1/200716_Thesis.pdf","source":{"id":"https://openalex.org/S4306402317","display_name":"Epsilon Open Archive (Sveriges lantbruksuniversitet biblioteket (Swedish University of Agricultural Sciences))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I298625061","host_organization_name":"Swedish University of Agricultural Sciences","host_organization_lineage":["https://openalex.org/I298625061"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pub.epsilon.slu.se/1438/1/200716_Thesis.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077586749","display_name":"Robert Jonasson-Kruse","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Robert Jonasson-Kruse","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5077586749"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13791","display_name":"Veterinary medicine and infectious diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13791","display_name":"Veterinary medicine and infectious diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/swine-dysentery","display_name":"swine dysentery","score":1.0},{"id":"https://openalex.org/keywords/brachyspira-hyodysenteriae","display_name":"Brachyspira hyodysenteriae","score":1.0},{"id":"https://openalex.org/keywords/experimental-infection","display_name":"experimental infection","score":0.7379999756813049},{"id":"https://openalex.org/keywords/pigs","display_name":"pigs","score":0.7210000157356262},{"id":"https://openalex.org/keywords/cytokines","display_name":"cytokines","score":0.699999988079071},{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.8149999976158142},{"id":"https://openalex.org/keywords/il-10","display_name":"IL-10","score":0.968999981880188},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8199999928474426},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.875},{"id":"https://openalex.org/keywords/serum-amyloid-a","display_name":"serum amyloid A","score":0.8709999918937683},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.7089999914169312},{"id":"https://openalex.org/keywords/gamma-delta-t-cells","display_name":"\u03b3\u03b4 T cells","score":0.7879999876022339},{"id":"https://openalex.org/keywords/amino-acid-metabolism","display_name":"amino acid metabolism","score":0.6880000233650208},{"id":"https://openalex.org/keywords/glutamine","display_name":"glutamine","score":0.8220000267028809},{"id":"https://openalex.org/keywords/monocytes","display_name":"monocytes","score":0.3619999885559082},{"id":"https://openalex.org/keywords/neutrophils","display_name":"neutrophils","score":0.9800000190734863},{"id":"https://openalex.org/keywords/humoral-immune-response","display_name":"humoral immune response","score":0.8130000233650208},{"id":"https://openalex.org/keywords/disease-susceptibility","display_name":"disease susceptibility","score":0.5740000009536743}],"concepts":[{"id":"https://openalex.org/C2780708024","wikidata":"https://www.wikidata.org/wiki/Q129279","display_name":"Dysentery","level":2,"score":0.7992346286773682},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.47530990839004517},{"id":"https://openalex.org/C2779349466","wikidata":"https://www.wikidata.org/wiki/Q181619","display_name":"Glutamine","level":3,"score":0.46402743458747864},{"id":"https://openalex.org/C2777761686","wikidata":"https://www.wikidata.org/wiki/Q715347","display_name":"Lymphocyte","level":2,"score":0.4361498951911926},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4326024055480957},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.40303051471710205},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.37107253074645996},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.26563799381256104},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1136033833026886}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:pub.epsilon.slu.se:1438","doi":null,"is_oa":true,"landing_page_url":"https://pub.epsilon.slu.se/1438/1/200716_Thesis.pdf","pdf_url":"https://pub.epsilon.slu.se/1438/1/200716_Thesis.pdf","source":{"id":"https://openalex.org/S4306402317","display_name":"Epsilon Open Archive (Sveriges lantbruksuniversitet biblioteket (Swedish University of Agricultural Sciences))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I298625061","host_organization_name":"Swedish University of Agricultural Sciences","host_organization_lineage":["https://openalex.org/I298625061"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:60212219","doi":null,"is_oa":false,"landing_page_url":"https://pub.epsilon.slu.se/1438/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:pub.epsilon.slu.se:1438","doi":null,"is_oa":true,"landing_page_url":"https://pub.epsilon.slu.se/1438/1/200716_Thesis.pdf","pdf_url":"https://pub.epsilon.slu.se/1438/1/200716_Thesis.pdf","source":{"id":"https://openalex.org/S4306402317","display_name":"Epsilon Open Archive (Sveriges lantbruksuniversitet biblioteket (Swedish University of Agricultural Sciences))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I298625061","host_organization_name":"Swedish University of Agricultural Sciences","host_organization_lineage":["https://openalex.org/I298625061"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899},{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.40450000762939453}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W60212219.pdf","grobid_xml":"https://content.openalex.org/works/W60212219.grobid-xml"},"referenced_works_count":118,"referenced_works":["https://openalex.org/W40321754","https://openalex.org/W100562756","https://openalex.org/W118466515","https://openalex.org/W178016293","https://openalex.org/W200753288","https://openalex.org/W216710021","https://openalex.org/W599903585","https://openalex.org/W1140384635","https://openalex.org/W1494364476","https://openalex.org/W1506139932","https://openalex.org/W1535243328","https://openalex.org/W1550310038","https://openalex.org/W1558294176","https://openalex.org/W1667507097","https://openalex.org/W1801379296","https://openalex.org/W1846277680","https://openalex.org/W1853319271","https://openalex.org/W1857206577","https://openalex.org/W1886756606","https://openalex.org/W1924983128","https://openalex.org/W1940719893","https://openalex.org/W1959145457","https://openalex.org/W1965141403","https://openalex.org/W1966805930","https://openalex.org/W1968587579","https://openalex.org/W1970141063","https://openalex.org/W1970151864","https://openalex.org/W1972120590","https://openalex.org/W1972571085","https://openalex.org/W1973350888","https://openalex.org/W1973739644","https://openalex.org/W1974524365","https://openalex.org/W1980220254","https://openalex.org/W1980856393","https://openalex.org/W1982178858","https://openalex.org/W1984035854","https://openalex.org/W1985344660","https://openalex.org/W1986151484","https://openalex.org/W1987162250","https://openalex.org/W1989238853","https://openalex.org/W1998079753","https://openalex.org/W2000233667","https://openalex.org/W2004003158","https://openalex.org/W2008180757","https://openalex.org/W2013199453","https://openalex.org/W2017056637","https://openalex.org/W2019376131","https://openalex.org/W2021569259","https://openalex.org/W2021993298","https://openalex.org/W2024100127","https://openalex.org/W2026215135","https://openalex.org/W2032913157","https://openalex.org/W2036072927","https://openalex.org/W2036082570","https://openalex.org/W2036287577","https://openalex.org/W2037653553","https://openalex.org/W2038736831","https://openalex.org/W2043536343","https://openalex.org/W2049121617","https://openalex.org/W2053940626","https://openalex.org/W2053989519","https://openalex.org/W2056167261","https://openalex.org/W2061102657","https://openalex.org/W2063700930","https://openalex.org/W2066918185","https://openalex.org/W2070126126","https://openalex.org/W2071106723","https://openalex.org/W2071287590","https://openalex.org/W2073447688","https://openalex.org/W2088461720","https://openalex.org/W2088958339","https://openalex.org/W2089102500","https://openalex.org/W2090000443","https://openalex.org/W2091562946","https://openalex.org/W2099401468","https://openalex.org/W2099563337","https://openalex.org/W2099588364","https://openalex.org/W2100837269","https://openalex.org/W2101542574","https://openalex.org/W2106160458","https://openalex.org/W2106656993","https://openalex.org/W2109825646","https://openalex.org/W2112857693","https://openalex.org/W2116403793","https://openalex.org/W2118296241","https://openalex.org/W2118666307","https://openalex.org/W2118872783","https://openalex.org/W2119352772","https://openalex.org/W2121950836","https://openalex.org/W2122686366","https://openalex.org/W2126169635","https://openalex.org/W2126751198","https://openalex.org/W2127296912","https://openalex.org/W2129469077","https://openalex.org/W2130517943","https://openalex.org/W2133367891","https://openalex.org/W2133908704","https://openalex.org/W2136054301","https://openalex.org/W2142584363","https://openalex.org/W2145065705","https://openalex.org/W2145229644","https://openalex.org/W2151222193","https://openalex.org/W2163543406","https://openalex.org/W2165429205","https://openalex.org/W2165715564","https://openalex.org/W2167914110","https://openalex.org/W2169427252","https://openalex.org/W2225437169","https://openalex.org/W2244254476","https://openalex.org/W2260709854","https://openalex.org/W2273512262","https://openalex.org/W2275522693","https://openalex.org/W2341235244","https://openalex.org/W2408915643","https://openalex.org/W2415624064","https://openalex.org/W2416524248","https://openalex.org/W2466733430","https://openalex.org/W4298375614"],"related_works":["https://openalex.org/W2003230300","https://openalex.org/W2032396861","https://openalex.org/W7098667707","https://openalex.org/W2244254476","https://openalex.org/W2945903171","https://openalex.org/W2169427252","https://openalex.org/W2040086765","https://openalex.org/W4400179198","https://openalex.org/W2618109247","https://openalex.org/W7097001750"],"abstract_inverted_index":{"Swine":[0],"dysentery":[1,86,134,161,171],"is":[2,7,14,25,41],"an":[3],"enteric":[4],"disease":[5,251],"that":[6,29,211,281],"present":[8],"in":[9,36,153,182,271,294],"most":[10],"pig-producing":[11],"countries.":[12],"It":[13],"caused":[15],"by":[16,298],"the":[17,22,49,84,99,107,131,139,149,158,163,170,173,183,195,222,225,228,233,243,282,291],"spirochete":[18],"Brachyspira":[19,63],"hyodysenteriae":[20,64,237],"and":[21,51,81,87,93,96,105,116,128,142,162,178,186,206,232,264,284],"typical":[23],"manifestation":[24,159],"severe":[26],"muco-haemorrhagic":[27],"diarrhoea":[28],"may":[30],"lead":[31],"to":[32,47,217,250,255,258,274],"a":[33,68,136],"high":[34,265],"mortality":[35],"affected":[37],"herds":[38],"if":[39],"it":[40],"left":[42],"untreated.":[43],"The":[44,122,146,248],"aim":[45],"was":[46,77,126,155],"study":[48],"immunological":[50],"metabolic":[52,292],"responses":[53,287],"associated":[54,156,241],"with":[55,62,72,135,157,242],"swine":[56,299],"dysentery.":[57,300],"Pigs":[58],"were":[59,120,208,215,240,296],"orally":[60],"inoculated":[61],"strain":[65],"B204R":[66],"after":[67,252],"provocative":[69],"feeding":[70],"regime":[71],"soy":[73],"bean":[74],"meal.":[75],"Blood":[76],"sampled":[78],"before":[79],"inoculation":[80,253],"repeatedly":[82],"during":[83,192,210,221],"incubation,":[85],"recovery":[88,244],"periods.":[89],"Counts":[90],"of":[91,98,130,138,148,160,165,175,198,227,235,245,261,267],"leucocyte":[92],"lymphocyte":[94],"sub-populations":[95],"levels":[97,188,220,260,266],"cytokines":[100],"IL-1beta,":[101],"IL-6,":[102],"Il-10,":[103],"TNF-alpha":[104],"IFN-gamma\uf02c":[106],"acute":[108],"phase":[109],"protein":[110],"Serum":[111,166],"Amyolid":[112],"A,":[113],"glucose,":[114],"lactate":[115,187],"18":[117],"amino":[118,200],"acids":[119],"determined.":[121],"experimental":[123],"infection":[124],"model":[125],"successful":[127],"~65%":[129],"pigs":[132],"developed":[133],"deterioration":[137],"body":[140],"condition":[141],"no":[143,190],"weight":[144],"gain.":[145],"presence":[147,226],"pro-inflammatory":[150],"cytokine":[151,230],"IL-1beta":[152],"serum":[154,196],"production":[164,234],"amyloid":[167],"A.":[168],"During":[169],"period":[172],"numbers":[174],"monocytes,":[176],"neutrophils":[177],"CD8alpha+":[179,262],"lymphocytes":[180,263],"increased":[181],"blood.":[184],"Glucose":[185],"showed":[189],"alteration":[191],"dysentery,":[193],"but":[194,224],"concentrations":[197],"gluconeogenic":[199],"acids,":[201],"mainly":[202],"glutamine,":[203],"alanine,":[204],"tyrosine":[205],"serine":[207],"decreased":[209],"period.":[212],"Most":[213],"parameters":[214],"returned":[216],"their":[218],"pre-inoculation":[219],"recovery,":[223],"anti-inflammatory":[229],"IL-10":[231],"B.":[236],"specific":[238],"antibodies":[239],"sick":[246],"animals.":[247],"susceptibility":[249],"appeared":[254],"be":[256],"related":[257],"low":[259],"gamma/delta":[268],"T":[269],"cells":[270],"blood":[272,295],"prior":[273],"inoculation.":[275],"In":[276],"conclusion,":[277],"this":[278],"thesis":[279],"shows":[280],"cellular":[283],"humoral":[285],"immune":[286],"as":[288,290],"well":[289],"response":[293],"altered":[297]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}
