{"id":"https://openalex.org/W600735947","doi":null,"title":"Pharmacological cardioprotection of the human myocardium in diseased states","display_name":"Pharmacological cardioprotection of the human myocardium in diseased states","publication_year":2011,"publication_date":"2011-12-28","ids":{"openalex":"https://openalex.org/W600735947","mag":"600735947"},"language":"en","primary_location":{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1336879","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1336879/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Doctoral thesis, UCL (University College London).","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019041116","display_name":"Paul S. C. Rees","orcid":"https://orcid.org/0000-0002-6560-6332","observed_orcids":["https://orcid.org/0000-0002-6560-6332"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Paul Rees","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6560-6332","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5019041116"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13796","display_name":"Neuroprotection in Cerebral Ischemia","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atorvastatin","display_name":"atorvastatin","score":0.9639999866485596},{"id":"https://openalex.org/keywords/cardioprotection","display_name":"cardioprotection","score":0.8920000195503235},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.9399999976158142},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.8930000066757202},{"id":"https://openalex.org/keywords/mitochondrial-permeability-transition-pore","display_name":"mitochondrial permeability transition pore","score":0.8399999737739563},{"id":"https://openalex.org/keywords/hypertrophic-cardiomyopathy","display_name":"hypertrophic cardiomyopathy","score":0.9210000038146973},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7940000295639038},{"id":"https://openalex.org/keywords/statins","display_name":"statins","score":0.6830000281333923},{"id":"https://openalex.org/keywords/atrial-myocardium","display_name":"atrial myocardium","score":0.8450000286102295},{"id":"https://openalex.org/keywords/reperfusion-therapy","display_name":"reperfusion therapy","score":0.6700000166893005}],"concepts":[{"id":"https://openalex.org/C2777482532","wikidata":"https://www.wikidata.org/wiki/Q668093","display_name":"Atorvastatin","level":2,"score":0.9123703241348267},{"id":"https://openalex.org/C13591479","wikidata":"https://www.wikidata.org/wiki/Q6881880","display_name":"Mitochondrial permeability transition pore","level":4,"score":0.8539531826972961},{"id":"https://openalex.org/C2779676291","wikidata":"https://www.wikidata.org/wiki/Q25325349","display_name":"Cardioprotection","level":3,"score":0.8318434953689575},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7011192440986633},{"id":"https://openalex.org/C2780114680","wikidata":"https://www.wikidata.org/wiki/Q1413991","display_name":"Reperfusion injury","level":3,"score":0.684524416923523},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.6082087159156799},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.570127546787262},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5537928342819214},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.5167747735977173},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3789489269256592},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.23082643747329712},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.22152841091156006},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.14101704955101013},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1336879","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1336879/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Doctoral thesis, UCL (University College London).","raw_type":"Thesis"},{"id":"mag:600735947","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/1336879","pdf_url":null,"source":{"id":"https://openalex.org/S4306508231","display_name":"Doctoral thesis, UCL (University College London).","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Doctoral thesis, UCL (University College London).","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":357,"referenced_works":["https://openalex.org/W21063540","https://openalex.org/W22056812","https://openalex.org/W67625574","https://openalex.org/W70102154","https://openalex.org/W146060167","https://openalex.org/W161836838","https://openalex.org/W178224015","https://openalex.org/W188288446","https://openalex.org/W201549064","https://openalex.org/W292832133","https://openalex.org/W1493556752","https://openalex.org/W1503760078","https://openalex.org/W1508666495","https://openalex.org/W1524299374","https://openalex.org/W1528594194","https://openalex.org/W1534290222","https://openalex.org/W1537398036","https://openalex.org/W1543177856","https://openalex.org/W1543797453","https://openalex.org/W1548990295","https://openalex.org/W1554269902","https://openalex.org/W1587098822","https://openalex.org/W1596397105","https://openalex.org/W1603109630","https://openalex.org/W1630602822","https://openalex.org/W1752451218","https://openalex.org/W1894853873","https://openalex.org/W1964736080","https://openalex.org/W1964972368","https://openalex.org/W1965466849","https://openalex.org/W1965808713","https://openalex.org/W1966726553","https://openalex.org/W1967594564","https://openalex.org/W1967800726","https://openalex.org/W1967980722","https://openalex.org/W1968233035","https://openalex.org/W1968574288","https://openalex.org/W1969100490","https://openalex.org/W1969354980","https://openalex.org/W1969912131","https://openalex.org/W1970988487","https://openalex.org/W1971079357","https://openalex.org/W1971242943","https://openalex.org/W1971730984","https://openalex.org/W1975981060","https://openalex.org/W1976114675","https://openalex.org/W1976389464","https://openalex.org/W1976791051","https://openalex.org/W1978480291","https://openalex.org/W1978960346","https://openalex.org/W1979048402","https://openalex.org/W1980051680","https://openalex.org/W1980322984","https://openalex.org/W1981795365","https://openalex.org/W1982715383","https://openalex.org/W1982815375","https://openalex.org/W1984305956","https://openalex.org/W1984588525","https://openalex.org/W1985889471","https://openalex.org/W1986011506","https://openalex.org/W1986398552","https://openalex.org/W1987457816","https://openalex.org/W1987522160","https://openalex.org/W1989018790","https://openalex.org/W1989057467","https://openalex.org/W1989214210","https://openalex.org/W1989312664","https://openalex.org/W1991365337","https://openalex.org/W1991490958","https://openalex.org/W1991615080","https://openalex.org/W1992001259","https://openalex.org/W1992115525","https://openalex.org/W1992591882","https://openalex.org/W1992988181","https://openalex.org/W1993380848","https://openalex.org/W1993488931","https://openalex.org/W1995893823","https://openalex.org/W1996038459","https://openalex.org/W1996510443","https://openalex.org/W1996867825","https://openalex.org/W1996892413","https://openalex.org/W1997821255","https://openalex.org/W1999052077","https://openalex.org/W2000409991","https://openalex.org/W2001059926","https://openalex.org/W2002830624","https://openalex.org/W2003980493","https://openalex.org/W2004957860","https://openalex.org/W2005150706","https://openalex.org/W2005350107","https://openalex.org/W2005585532","https://openalex.org/W2006137307","https://openalex.org/W2006380274","https://openalex.org/W2006687337","https://openalex.org/W2006933647","https://openalex.org/W2007114641","https://openalex.org/W2009897696","https://openalex.org/W2010267145","https://openalex.org/W2010791119","https://openalex.org/W2011406618","https://openalex.org/W2013541018","https://openalex.org/W2014237668","https://openalex.org/W2014318373","https://openalex.org/W2014366692","https://openalex.org/W2020538365","https://openalex.org/W2020686426","https://openalex.org/W2021917695","https://openalex.org/W2022473516","https://openalex.org/W2022547886","https://openalex.org/W2023400978","https://openalex.org/W2023723492","https://openalex.org/W2024162358","https://openalex.org/W2024214116","https://openalex.org/W2024870847","https://openalex.org/W2026313838","https://openalex.org/W2026826353","https://openalex.org/W2027337381","https://openalex.org/W2028934633","https://openalex.org/W2029077404","https://openalex.org/W2029469053","https://openalex.org/W2030209755","https://openalex.org/W2031469256","https://openalex.org/W2031663994","https://openalex.org/W2031819161","https://openalex.org/W2032580133","https://openalex.org/W2032715486","https://openalex.org/W2032739581","https://openalex.org/W2033246651","https://openalex.org/W2033333921","https://openalex.org/W2035860935","https://openalex.org/W2036340138","https://openalex.org/W2036623116","https://openalex.org/W2036841022","https://openalex.org/W2037098361","https://openalex.org/W2037159578","https://openalex.org/W2037210083","https://openalex.org/W2039502637","https://openalex.org/W2040021196","https://openalex.org/W2040540566","https://openalex.org/W2041255585","https://openalex.org/W2043131158","https://openalex.org/W2044211202","https://openalex.org/W2044454450","https://openalex.org/W2044846711","https://openalex.org/W2044943191","https://openalex.org/W2044973211","https://openalex.org/W2045371665","https://openalex.org/W2047273318","https://openalex.org/W2047373489","https://openalex.org/W2047605126","https://openalex.org/W2048017944","https://openalex.org/W2048543877","https://openalex.org/W2048813801","https://openalex.org/W2049373326","https://openalex.org/W2049461872","https://openalex.org/W2051035231","https://openalex.org/W2051441972","https://openalex.org/W2051533145","https://openalex.org/W2051861915","https://openalex.org/W2052317742","https://openalex.org/W2053786249","https://openalex.org/W2054079638","https://openalex.org/W2054718950","https://openalex.org/W2054908104","https://openalex.org/W2056521469","https://openalex.org/W2057694036","https://openalex.org/W2057694525","https://openalex.org/W2058128468","https://openalex.org/W2058166616","https://openalex.org/W2059289792","https://openalex.org/W2059829634","https://openalex.org/W2062568312","https://openalex.org/W2062688683","https://openalex.org/W2062976933","https://openalex.org/W2063596153","https://openalex.org/W2063893017","https://openalex.org/W2064525822","https://openalex.org/W2064722566","https://openalex.org/W2064772676","https://openalex.org/W2065016765","https://openalex.org/W2065825082","https://openalex.org/W2066119862","https://openalex.org/W2066600490","https://openalex.org/W2067185367","https://openalex.org/W2068967760","https://openalex.org/W2070320179","https://openalex.org/W2071072621","https://openalex.org/W2072091889","https://openalex.org/W2072631306","https://openalex.org/W2073751205","https://openalex.org/W2074098680","https://openalex.org/W2074321180","https://openalex.org/W2075652728","https://openalex.org/W2076110739","https://openalex.org/W2076396661","https://openalex.org/W2076992606","https://openalex.org/W2077997475","https://openalex.org/W2078113728","https://openalex.org/W2080045599","https://openalex.org/W2080128777","https://openalex.org/W2080312195","https://openalex.org/W2080514250","https://openalex.org/W2080624217","https://openalex.org/W2081787098","https://openalex.org/W2082231490","https://openalex.org/W2086938764","https://openalex.org/W2087398999","https://openalex.org/W2087542228","https://openalex.org/W2087743052","https://openalex.org/W2087805943","https://openalex.org/W2089496934","https://openalex.org/W2089758120","https://openalex.org/W2089785801","https://openalex.org/W2090767212","https://openalex.org/W2091064074","https://openalex.org/W2091949587","https://openalex.org/W2092316845","https://openalex.org/W2092438446","https://openalex.org/W2092859665","https://openalex.org/W2093147781","https://openalex.org/W2093369326","https://openalex.org/W2094138142","https://openalex.org/W2094941678","https://openalex.org/W2096748759","https://openalex.org/W2097435560","https://openalex.org/W2097767970","https://openalex.org/W2098671530","https://openalex.org/W2098885552","https://openalex.org/W2100039277","https://openalex.org/W2103636227","https://openalex.org/W2105587401","https://openalex.org/W2109004272","https://openalex.org/W2109245865","https://openalex.org/W2110108344","https://openalex.org/W2111340301","https://openalex.org/W2112334970","https://openalex.org/W2113058623","https://openalex.org/W2113123117","https://openalex.org/W2113844183","https://openalex.org/W2114009175","https://openalex.org/W2114205159","https://openalex.org/W2114276035","https://openalex.org/W2115276402","https://openalex.org/W2115830594","https://openalex.org/W2116899872","https://openalex.org/W2117254307","https://openalex.org/W2117344826","https://openalex.org/W2117571600","https://openalex.org/W2118154631","https://openalex.org/W2120194464","https://openalex.org/W2120261681","https://openalex.org/W2121504382","https://openalex.org/W2121691431","https://openalex.org/W2122202708","https://openalex.org/W2123777286","https://openalex.org/W2124069969","https://openalex.org/W2124922259","https://openalex.org/W2126636055","https://openalex.org/W2126801906","https://openalex.org/W2127783148","https://openalex.org/W2128209215","https://openalex.org/W2128788602","https://openalex.org/W2128883750","https://openalex.org/W2128960919","https://openalex.org/W2129167542","https://openalex.org/W2129282872","https://openalex.org/W2129992226","https://openalex.org/W2130345110","https://openalex.org/W2131015734","https://openalex.org/W2131039042","https://openalex.org/W2131933499","https://openalex.org/W2132795540","https://openalex.org/W2135217811","https://openalex.org/W2136009429","https://openalex.org/W2136272230","https://openalex.org/W2137035181","https://openalex.org/W2137445925","https://openalex.org/W2137835651","https://openalex.org/W2137962262","https://openalex.org/W2137977069","https://openalex.org/W2137983259","https://openalex.org/W2138488002","https://openalex.org/W2140991303","https://openalex.org/W2142387793","https://openalex.org/W2144623639","https://openalex.org/W2144808837","https://openalex.org/W2145048322","https://openalex.org/W2145653235","https://openalex.org/W2145675902","https://openalex.org/W2146072223","https://openalex.org/W2146217294","https://openalex.org/W2146228563","https://openalex.org/W2146350062","https://openalex.org/W2147114673","https://openalex.org/W2147640676","https://openalex.org/W2147791296","https://openalex.org/W2149396086","https://openalex.org/W2149422196","https://openalex.org/W2149609916","https://openalex.org/W2151482910","https://openalex.org/W2151492048","https://openalex.org/W2153298328","https://openalex.org/W2155238154","https://openalex.org/W2155244168","https://openalex.org/W2155598961","https://openalex.org/W2155638956","https://openalex.org/W2155668811","https://openalex.org/W2156495678","https://openalex.org/W2156927593","https://openalex.org/W2159230072","https://openalex.org/W2159443173","https://openalex.org/W2159449551","https://openalex.org/W2159505514","https://openalex.org/W2160094856","https://openalex.org/W2160152341","https://openalex.org/W2160414137","https://openalex.org/W2160696128","https://openalex.org/W2160994935","https://openalex.org/W2161612659","https://openalex.org/W2162003329","https://openalex.org/W2162603308","https://openalex.org/W2163072437","https://openalex.org/W2163230619","https://openalex.org/W2164403578","https://openalex.org/W2164823158","https://openalex.org/W2166910397","https://openalex.org/W2167887751","https://openalex.org/W2168978330","https://openalex.org/W2169928616","https://openalex.org/W2170098235","https://openalex.org/W2170347547","https://openalex.org/W2170350762","https://openalex.org/W2170472977","https://openalex.org/W2170525268","https://openalex.org/W2171466485","https://openalex.org/W2207321888","https://openalex.org/W2216556768","https://openalex.org/W2229244411","https://openalex.org/W2247997571","https://openalex.org/W2262211743","https://openalex.org/W2272705881","https://openalex.org/W2274632797","https://openalex.org/W2293071223","https://openalex.org/W2323905261","https://openalex.org/W2324535815","https://openalex.org/W2331162989","https://openalex.org/W2334499091","https://openalex.org/W2335335726","https://openalex.org/W2336925175","https://openalex.org/W2412535759","https://openalex.org/W2417306507","https://openalex.org/W2469132858","https://openalex.org/W2607412715","https://openalex.org/W2743152260","https://openalex.org/W3134574291","https://openalex.org/W4237762834","https://openalex.org/W4246764494"],"related_works":["https://openalex.org/W2411740792","https://openalex.org/W774847430","https://openalex.org/W57630350","https://openalex.org/W70102154","https://openalex.org/W1971730984","https://openalex.org/W2358624443","https://openalex.org/W2597533422","https://openalex.org/W2385407489","https://openalex.org/W7162211007","https://openalex.org/W2363835168"],"abstract_inverted_index":{"BACKGROUND:":[0],"Coronary":[1],"artery":[2],"disease":[3],"is":[4,24,53,222,254],"the":[5,27,54,73,76,113,127,139,147,150,160,200,249,267,271],"leading":[6],"worldwide":[7],"cause":[8],"of":[9,14,72,75,98,115,129,141,149,162,202,244,251,256,260,274,293],"death.":[10],"Even":[11],"despite":[12],"restoration":[13],"blood":[15],"flow":[16],"following":[17,168],"acute":[18,118],"myocardial":[19,22,252],"infarction,":[20],"further":[21],"damage":[23],"seen":[25],"during":[26],"reperfusion":[28,37,246],"phase.":[29],"Pharmacological":[30],"strategies":[31],"to":[32,35,42,90,132,177,266],"induce":[33],"resistance":[34],"ischaemia":[36],"injury":[38,122,180,194,209],"have":[39,182],"been":[40,88,105],"shown":[41,89],"share":[43],"common":[44,49],"pathways.":[45],"The":[46,217,241],"most":[47],"important":[48],"signalling":[50],"pathway":[51],"involved":[52],"Reperfusion":[55],"Injury":[56],"Salvage":[57],"Kinase":[58],"pathway,":[59],"and":[60,145,159,232,258,279,296],"in":[61,70,92,95,107,117,123,135,138,155,164,226,229,248,276,290,301],"animal":[62,96],"models":[63,97,176],"this":[64,93,102],"can":[65,188,210,235],"be":[66,189,211,236],"pharmacologically":[67],"activated,":[68],"resulting":[69],"inhibition":[71,234],"opening":[74,167],"mitochondrial":[77,151,218],"permeability":[78,152,219],"transition":[79,153,220],"pore,":[80],"with":[81,197,213],"a":[82,223,286],"resultant":[83],"cardioprotective":[84,272],"effect.":[85],"Atorvastatin":[86],"has":[87,103],"act":[91],"way":[94],"ischaemia-reperfusion":[99,121,179,193,208],"injury,":[100],"although":[101],"not":[104],"demonstrated":[106],"humans.":[108],"This":[109],"thesis":[110],"examines":[111],"(a)":[112],"role":[114,161],"atorvastatin":[116,131,163,198,275],"protection":[119],"from":[120,191],"human":[124,136,156,175,277],"myocardium,":[125],"(b)":[126],"ability":[128],"high-dose":[130,214],"recapture":[133],"cardioprotection":[134,300],"myocardium":[137,187,257,278],"setting":[140,250],"chronic":[142],"statin":[143,294],"therapy,":[144],"(c)":[146],"functionality":[148],"pore":[154,166,221],"hypertrophic":[157,230,302],"cardiomyopathy,":[158,231],"inhibiting":[165],"oxidative":[169],"stress.":[170],"METHODS":[171],"AND":[172],"RESULTS:":[173],"Using":[174],"simulate":[178],"we":[181],"demonstrated:":[183],"(1)":[184],"Human":[185],"atrial":[186],"protected":[190],"simulated":[192,207],"by":[195,269],"treatment":[196],"at":[199],"time":[201],"reperfusion;":[203],"(2)":[204],"Cardioprotection":[205],"against":[206],"recaptured":[212],"atorvastatin;":[215],"(3)":[216],"critical":[224],"determinant":[225],"cell":[227],"death":[228],"its":[233],"achieved":[237],"using":[238],"atorvastatin.":[239],"\\nCONCLUSION:":[240],"key":[242,287],"aim":[243],"emergency":[245],"therapy":[247],"infarction":[253],"salvage":[255],"preservation":[259],"cardiac":[261],"function.":[262],"These":[263],"studies":[264],"contribute":[265],"field":[268],"exploring":[270],"effects":[273],"delineating":[280],"protective":[281],"cascades":[282],"involved.":[283],"They":[284],"offer":[285],"translational":[288],"step":[289],"our":[291],"understanding":[292],"cardioprotection,":[295],"an":[297],"insight":[298],"into":[299],"cardiomyopathy.":[303]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}