{"id":"https://openalex.org/W60070576","doi":null,"title":"[Multivariate analysis of aminoacyl-tRNA synthetase activities of liver and hepatomas (author's transl)].","display_name":"[Multivariate analysis of aminoacyl-tRNA synthetase activities of liver and hepatomas (author's transl)].","publication_year":1975,"publication_date":"1975-05-01","ids":{"openalex":"https://openalex.org/W60070576","mag":"60070576","pmid":"https://pubmed.ncbi.nlm.nih.gov/169616"},"language":"it","primary_location":{"id":"pmid:169616","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/169616","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tumori","raw_type":"English Abstract"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040075641","display_name":"Ugo Del Monte","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"U Del Monte","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108593260","display_name":"V Boddi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Boddi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008953388","display_name":"Riccardo Caldini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Caldini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041907962","display_name":"Pasquale Urbano","orcid":"https://orcid.org/0000-0001-7099-9583","observed_orcids":["https://orcid.org/0000-0001-7099-9583"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P Urbano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5003842831","display_name":"Grazia Cini","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Cini","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.00271083,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"61","issue":"3","first_page":"304","last_page":"12"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9945999979972839,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14135","display_name":"Cancer and biochemical research","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/aminoacyl-trna-synthetase","display_name":"aminoacyl-tRNA synthetase","score":0.996999979019165},{"id":"https://openalex.org/keywords/liver","display_name":"liver","score":0.5879999995231628},{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.7089999914169312},{"id":"https://openalex.org/keywords/enzyme-activity-patterns","display_name":"enzyme activity patterns","score":0.7429999709129333},{"id":"https://openalex.org/keywords/enzyme-regulation","display_name":"enzyme regulation","score":0.7039999961853027},{"id":"https://openalex.org/keywords/factor-analysis","display_name":"factor analysis","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C2779315393","wikidata":"https://www.wikidata.org/wiki/Q415968","display_name":"Aminoacyl tRNA synthetase","level":5,"score":0.7438009977340698},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.7271232604980469},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.5532867908477783},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.45020240545272827},{"id":"https://openalex.org/C2992176824","wikidata":"https://www.wikidata.org/wiki/Q9368","display_name":"Liver tissue","level":2,"score":0.44767630100250244},{"id":"https://openalex.org/C3020359197","wikidata":"https://www.wikidata.org/wiki/Q1359801","display_name":"Liver enzyme","level":2,"score":0.44686123728752136},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4453512132167816},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3495364487171173},{"id":"https://openalex.org/C153957851","wikidata":"https://www.wikidata.org/wiki/Q201448","display_name":"Transfer RNA","level":4,"score":0.3413575291633606},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2606211304664612},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.21542730927467346},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09169164299964905},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.06470096111297607},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.06420081853866577}],"mesh":[{"descriptor_ui":"D000604","descriptor_name":"Amino Acyl-tRNA Synthetases","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006528","descriptor_name":"Carcinoma, Hepatocellular","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D008113","descriptor_name":"Liver Neoplasms","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D009374","descriptor_name":"Neoplasms, Experimental","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:169616","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/169616","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tumori","raw_type":"English Abstract"},{"id":"mag:60070576","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/169616","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.504800021648407,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2802151550","https://openalex.org/W2075869606","https://openalex.org/W2159673129","https://openalex.org/W2074415899","https://openalex.org/W2109034357","https://openalex.org/W2005537998","https://openalex.org/W2155454691","https://openalex.org/W1516602132","https://openalex.org/W1544945892","https://openalex.org/W2060967317"],"abstract_inverted_index":{"Data":[0],"on":[1,58,73,103],"the":[2,46,68,76,80,89,107,118,130],"aminoacyl-tRNA":[3,70],"synthetase":[4],"activities":[5,83],"in":[6,10,137,141],"normal":[7,138],"liver":[8,139],"and":[9,19,22,126,140],"three":[11],"transplantable":[12],"rat":[13],"hepatomas,":[14],"viz":[15],"Yoshida's":[16],"AH":[17],"130":[18],"Morris's":[20],"5123C":[21],"7793,":[23],"were":[24],"studied":[25],"by":[26,88],"means":[27],"of":[28,34,48,61,67,75,79,129],"factor":[29],"analysis,":[30],"a":[31,122],"powerful":[32],"technique":[33],"multivariate":[35],"analysis":[36,54],"particularly":[37],"suitable":[38],"foridentifying":[39],"factors":[40,92,108],"which":[41],"theoretically":[42],"may":[43,84],"account":[44],"for":[45,87],"pattern":[47],"interrelations":[49],"between":[50],"several":[51],"variables.":[52],"The":[53,94,111],"has":[55],"been":[56],"performed":[57],"51":[59],"patterns":[60],"enzyme":[62,82],"activities,":[63],"covering":[64],"17":[65,81],"out":[66],"20":[69],"synthetases;":[71],"80%":[72],"average":[74],"total":[77],"variability":[78],"be":[85],"accounted":[86],"first":[90],"4":[91],"extracted.":[93],"enzymes":[95,115,131],"seem":[96],"to":[97,117,133],"fall":[98],"into":[99],"different":[100,134],"groups,":[101,135],"depending":[102],"their":[104],"relationship":[105],"with":[106],"thus":[109],"identified.":[110],"results":[112],"suggest":[113],"that":[114],"belonging":[116,132],"same":[119],"group":[120],"share":[121],"common":[123],"control":[124],"mechanism,":[125],"are":[127],"independent":[128],"both":[136],"hepatomas.":[142]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}