{"id":"https://openalex.org/W60027085","doi":null,"title":"Type-2 diabetes and innate immunity : new connections revealed by multi-dimensional fractionation of blood plasma prior to proteomic analysis","display_name":"Type-2 diabetes and innate immunity : new connections revealed by multi-dimensional fractionation of blood plasma prior to proteomic analysis","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W60027085","mag":"60027085"},"language":"en","primary_location":{"id":"pmh:oai:scholarworks.montana.edu:1/1689","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.montana.edu/xmlui/handle/1/1689","pdf_url":"https://scholarworks.montana.edu/xmlui/handle/1/1689","source":{"id":"https://openalex.org/S4306402563","display_name":"Montana State University ScholarWorks (Montana State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I23732399","host_organization_name":"Montana State University","host_organization_lineage":["https://openalex.org/I23732399"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://scholarworks.montana.edu/xmlui/handle/1/1689","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080072525","display_name":"Scott B. Laffoon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Scott B. Laffoon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5080072525"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"368"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9063000082969666,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.9063000082969666,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.05550000071525574,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9589999914169312},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.9810000061988831},{"id":"https://openalex.org/keywords/plasma-proteome","display_name":"plasma proteome","score":0.6679999828338623},{"id":"https://openalex.org/keywords/protein-isoforms","display_name":"protein isoforms","score":0.949999988079071},{"id":"https://openalex.org/keywords/haptoglobin","display_name":"haptoglobin","score":0.9950000047683716},{"id":"https://openalex.org/keywords/apolipoprotein-a-i","display_name":"apolipoprotein A-I","score":0.8259999752044678},{"id":"https://openalex.org/keywords/human-serum-albumin-binding","display_name":"human serum albumin binding","score":0.8769999742507935},{"id":"https://openalex.org/keywords/protein-oxidation","display_name":"protein oxidation","score":0.5059999823570251},{"id":"https://openalex.org/keywords/carbonylation","display_name":"carbonylation","score":0.4519999921321869}],"concepts":[{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.7816766500473022},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.49205559492111206},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.488309383392334},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.4835622012615204},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4406229853630066},{"id":"https://openalex.org/C97428945","wikidata":"https://www.wikidata.org/wiki/Q15305109","display_name":"Fractionation","level":2,"score":0.4237726032733917},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4080454707145691},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40614205598831177},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34831058979034424},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21006456017494202},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.15104687213897705},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.11604833602905273},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.04838240146636963}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:scholarworks.montana.edu:1/1689","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.montana.edu/xmlui/handle/1/1689","pdf_url":"https://scholarworks.montana.edu/xmlui/handle/1/1689","source":{"id":"https://openalex.org/S4306402563","display_name":"Montana State University ScholarWorks (Montana State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I23732399","host_organization_name":"Montana State University","host_organization_lineage":["https://openalex.org/I23732399"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},{"id":"mag:60027085","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.montana.edu/xmlui/handle/1/1689","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:scholarworks.montana.edu:1/1689","doi":null,"is_oa":true,"landing_page_url":"https://scholarworks.montana.edu/xmlui/handle/1/1689","pdf_url":"https://scholarworks.montana.edu/xmlui/handle/1/1689","source":{"id":"https://openalex.org/S4306402563","display_name":"Montana State University ScholarWorks (Montana State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I23732399","host_organization_name":"Montana State University","host_organization_lineage":["https://openalex.org/I23732399"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W60027085.pdf","grobid_xml":"https://content.openalex.org/works/W60027085.grobid-xml"},"referenced_works_count":285,"referenced_works":["https://openalex.org/W11598776","https://openalex.org/W92262777","https://openalex.org/W164150996","https://openalex.org/W299255587","https://openalex.org/W571220549","https://openalex.org/W983550643","https://openalex.org/W1492605893","https://openalex.org/W1499495082","https://openalex.org/W1520092900","https://openalex.org/W1529592271","https://openalex.org/W1535567348","https://openalex.org/W1582388915","https://openalex.org/W1606423922","https://openalex.org/W1697523131","https://openalex.org/W1804813305","https://openalex.org/W1871924278","https://openalex.org/W1907441899","https://openalex.org/W1922526566","https://openalex.org/W1926159205","https://openalex.org/W1927710737","https://openalex.org/W1928704669","https://openalex.org/W1947043095","https://openalex.org/W1955212334","https://openalex.org/W1961993092","https://openalex.org/W1963739832","https://openalex.org/W1964574933","https://openalex.org/W1964986459","https://openalex.org/W1966091911","https://openalex.org/W1966419887","https://openalex.org/W1966882402","https://openalex.org/W1967239474","https://openalex.org/W1969018508","https://openalex.org/W1969480413","https://openalex.org/W1970463993","https://openalex.org/W1970673696","https://openalex.org/W1971654402","https://openalex.org/W1972909533","https://openalex.org/W1973238993","https://openalex.org/W1975578943","https://openalex.org/W1975999145","https://openalex.org/W1976422365","https://openalex.org/W1977892627","https://openalex.org/W1977913875","https://openalex.org/W1978915310","https://openalex.org/W1979355058","https://openalex.org/W1979973713","https://openalex.org/W1980564720","https://openalex.org/W1981073043","https://openalex.org/W1981361599","https://openalex.org/W1984896763","https://openalex.org/W1985469212","https://openalex.org/W1985947600","https://openalex.org/W1986131332","https://openalex.org/W1986734188","https://openalex.org/W1987481001","https://openalex.org/W1988556197","https://openalex.org/W1988870963","https://openalex.org/W1989576620","https://openalex.org/W1989742048","https://openalex.org/W1992522036","https://openalex.org/W1992730111","https://openalex.org/W1995000970","https://openalex.org/W1996444620","https://openalex.org/W1997295916","https://openalex.org/W1997458078","https://openalex.org/W1997581710","https://openalex.org/W1998009398","https://openalex.org/W1999128746","https://openalex.org/W1999428392","https://openalex.org/W1999917690","https://openalex.org/W2000054651","https://openalex.org/W2000375736","https://openalex.org/W2001527376","https://openalex.org/W2001825478","https://openalex.org/W2002192155","https://openalex.org/W2002396315","https://openalex.org/W2002834562","https://openalex.org/W2003323316","https://openalex.org/W2004476742","https://openalex.org/W2005211913","https://openalex.org/W2005227623","https://openalex.org/W2007413963","https://openalex.org/W2007527212","https://openalex.org/W2007790334","https://openalex.org/W2008495217","https://openalex.org/W2008869160","https://openalex.org/W2009118138","https://openalex.org/W2009480581","https://openalex.org/W2010447832","https://openalex.org/W2011658568","https://openalex.org/W2011960082","https://openalex.org/W2012295774","https://openalex.org/W2013234359","https://openalex.org/W2014477053","https://openalex.org/W2014804054","https://openalex.org/W2014887370","https://openalex.org/W2016839547","https://openalex.org/W2017042103","https://openalex.org/W2017199538","https://openalex.org/W2017378856","https://openalex.org/W2018135697","https://openalex.org/W2018235438","https://openalex.org/W2019226618","https://openalex.org/W2019570781","https://openalex.org/W2019642669","https://openalex.org/W2020796595","https://openalex.org/W2021838776","https://openalex.org/W2022380963","https://openalex.org/W2022381933","https://openalex.org/W2023041575","https://openalex.org/W2023070904","https://openalex.org/W2025398535","https://openalex.org/W2025524111","https://openalex.org/W2026703782","https://openalex.org/W2027324881","https://openalex.org/W2027670788","https://openalex.org/W2028212562","https://openalex.org/W2029952770","https://openalex.org/W2030116431","https://openalex.org/W2031805664","https://openalex.org/W2032422942","https://openalex.org/W2033125833","https://openalex.org/W2033189690","https://openalex.org/W2033381823","https://openalex.org/W2033979611","https://openalex.org/W2034900477","https://openalex.org/W2034926930","https://openalex.org/W2035726643","https://openalex.org/W2036916827","https://openalex.org/W2037028566","https://openalex.org/W2038331836","https://openalex.org/W2040005689","https://openalex.org/W2040330044","https://openalex.org/W2043106623","https://openalex.org/W2043324706","https://openalex.org/W2043498565","https://openalex.org/W2043605564","https://openalex.org/W2043768600","https://openalex.org/W2043772063","https://openalex.org/W2044437167","https://openalex.org/W2045351361","https://openalex.org/W2045487874","https://openalex.org/W2045687167","https://openalex.org/W2046095066","https://openalex.org/W2046503553","https://openalex.org/W2047867647","https://openalex.org/W2048325240","https://openalex.org/W2048333869","https://openalex.org/W2048563316","https://openalex.org/W2048966030","https://openalex.org/W2049858570","https://openalex.org/W2050217807","https://openalex.org/W2050465072","https://openalex.org/W2050473688","https://openalex.org/W2052266313","https://openalex.org/W2053670472","https://openalex.org/W2054231550","https://openalex.org/W2054562834","https://openalex.org/W2055718211","https://openalex.org/W2056677038","https://openalex.org/W2057981766","https://openalex.org/W2058610272","https://openalex.org/W2059511498","https://openalex.org/W2059842910","https://openalex.org/W2060431825","https://openalex.org/W2061248440","https://openalex.org/W2062078854","https://openalex.org/W2063243157","https://openalex.org/W2063983815","https://openalex.org/W2064119981","https://openalex.org/W2066290187","https://openalex.org/W2070384620","https://openalex.org/W2070642086","https://openalex.org/W2071073097","https://openalex.org/W2073620575","https://openalex.org/W2073759997","https://openalex.org/W2075171810","https://openalex.org/W2075241233","https://openalex.org/W2075924104","https://openalex.org/W2076428562","https://openalex.org/W2076749390","https://openalex.org/W2079080809","https://openalex.org/W2080237681","https://openalex.org/W2081393100","https://openalex.org/W2081584258","https://openalex.org/W2083990676","https://openalex.org/W2085318288","https://openalex.org/W2086273061","https://openalex.org/W2086547011","https://openalex.org/W2086561195","https://openalex.org/W2089348849","https://openalex.org/W2092007009","https://openalex.org/W2092435249","https://openalex.org/W2093255361","https://openalex.org/W2095780917","https://openalex.org/W2096330355","https://openalex.org/W2096773810","https://openalex.org/W2098169357","https://openalex.org/W2099529905","https://openalex.org/W2104969843","https://openalex.org/W2106563675","https://openalex.org/W2108605614","https://openalex.org/W2108931588","https://openalex.org/W2109514988","https://openalex.org/W2111645882","https://openalex.org/W2112366494","https://openalex.org/W2112520390","https://openalex.org/W2114041992","https://openalex.org/W2118445583","https://openalex.org/W2118520252","https://openalex.org/W2119595824","https://openalex.org/W2120220517","https://openalex.org/W2120282127","https://openalex.org/W2120430903","https://openalex.org/W2123276507","https://openalex.org/W2123946565","https://openalex.org/W2124706352","https://openalex.org/W2125775385","https://openalex.org/W2126383455","https://openalex.org/W2126736180","https://openalex.org/W2128988773","https://openalex.org/W2129316761","https://openalex.org/W2130381045","https://openalex.org/W2130850001","https://openalex.org/W2132785801","https://openalex.org/W2133800593","https://openalex.org/W2134969640","https://openalex.org/W2136024338","https://openalex.org/W2136942127","https://openalex.org/W2136989779","https://openalex.org/W2137401868","https://openalex.org/W2138590740","https://openalex.org/W2139807366","https://openalex.org/W2140434971","https://openalex.org/W2140665078","https://openalex.org/W2140699761","https://openalex.org/W2141721370","https://openalex.org/W2142584363","https://openalex.org/W2143869152","https://openalex.org/W2144473676","https://openalex.org/W2144979640","https://openalex.org/W2145224695","https://openalex.org/W2146877877","https://openalex.org/W2147084771","https://openalex.org/W2148294117","https://openalex.org/W2149424567","https://openalex.org/W2150479300","https://openalex.org/W2151027431","https://openalex.org/W2152187001","https://openalex.org/W2152360410","https://openalex.org/W2152377123","https://openalex.org/W2152591650","https://openalex.org/W2152727172","https://openalex.org/W2154789716","https://openalex.org/W2158822657","https://openalex.org/W2159954232","https://openalex.org/W2160440716","https://openalex.org/W2164252720","https://openalex.org/W2166256210","https://openalex.org/W2166998713","https://openalex.org/W2168176965","https://openalex.org/W2168536185","https://openalex.org/W2170838054","https://openalex.org/W2172092453","https://openalex.org/W2172116519","https://openalex.org/W2175474731","https://openalex.org/W2272776788","https://openalex.org/W2317184793","https://openalex.org/W2327628147","https://openalex.org/W2327640792","https://openalex.org/W2332362056","https://openalex.org/W2334309509","https://openalex.org/W2334902808","https://openalex.org/W2336304679","https://openalex.org/W2340653003","https://openalex.org/W2341717561","https://openalex.org/W2398160408","https://openalex.org/W2402623008","https://openalex.org/W2471605942","https://openalex.org/W2487057021","https://openalex.org/W2769264260","https://openalex.org/W3144316255","https://openalex.org/W3180361994","https://openalex.org/W4213392016","https://openalex.org/W4244383122"],"related_works":["https://openalex.org/W3149535453","https://openalex.org/W2025939483","https://openalex.org/W2921641322","https://openalex.org/W1991399038","https://openalex.org/W202455788","https://openalex.org/W2096055664","https://openalex.org/W2055694299","https://openalex.org/W2589888736","https://openalex.org/W7145529614","https://openalex.org/W2892925201"],"abstract_inverted_index":{"We":[0,29,278],"compared":[1],"levels":[2,160,307],"of":[3,32,88,111,117,125,132,147,161,177,201,221,236,244,250,264,274,281,286,297,308,312,320,341,349],"protein":[4,150],"isoforms":[5,110],"in":[6,23,154,157,293],"human":[7,189],"blood":[8],"plasma":[9,39,159,254,298,321],"from":[10,26,37,56],"patients":[11],"with":[12,20,61,240,301,324,333,344],"newly":[13],"diagnosed":[14],"and":[15,41,67,76,95,106,134,163,198,331],"untreated":[16],"type-2":[17],"diabetes":[18],"(T2DM)":[19],"non-diabetic":[21],"controls":[22],"samples":[24,40,45],"obtained":[25],"US":[27],"NIH.":[28],"immunodepleted":[30],"fourteen":[31],"the":[33,43,144,158,166,186,219,237,248,271,291,309,325],"most":[34],"abundant":[35],"proteins":[36,105,179,299,322],"pooled":[38],"separated":[42],"depleted":[44],"into":[46],"six":[47],"fractions":[48,58],"by":[49,225],"reverse-phase":[50],"liquid":[51],"chromatography":[52],"at":[53,74,227],"80\u00b0C.":[54],"Proteins":[55],"these":[57,178],"were":[59],"labeled":[60],"new":[62],"high":[63],"quantum":[64],"yield,":[65],"hydrophilic":[66],"spectrally":[68],"resolved":[69,77],"fluorescent":[70],"detection":[71],"dyes":[72],"developed":[73,269],"MSU":[75],"on":[78],"large-format":[79],"(24cm":[80],"x":[81],"20cm)":[82],"two-dimensional":[83],"gels.":[84],"By":[85],"fluorescence":[86],"analysis":[87],"2D":[89],"gels,":[90],"using":[91],">1.4":[92],"fold":[93],"change":[94],"p<0.05":[96],"acceptance":[97],"criteria,":[98],"we":[99,216],"have":[100],"identified":[101],"five":[102],"T2DM":[103,169],"associated":[104],"isoforms,":[107],"including:":[108],"two":[109],"zinc-alpha":[112],"glycoprotein":[113],"(ZAG),":[114],"one":[115,123,130],"isoform":[116,124,131],"serum":[118,190],"amyloid":[119],"A-1":[120],"(SAA-1)":[121],"preprotein,":[122],"cysteine-rich":[126],"secreted":[127],"protein-3":[128],"(CRISP-3),":[129],"haptoglobin,":[133],"an":[135,208,347],"A1-apolipoprotein":[136],"fragment.":[137],"Complement":[138],"factor":[139],"H":[140],"related-5":[141],"(CFHR-5)":[142],"is":[143,170,195,207],"likely":[145],"identification":[146],"a":[148,171,196,222,338],"sixth":[149],"found":[151],"significantly":[152],"down":[153],"T2DM.":[155],"Changes":[156],"CRISP-3":[162,194],"CFHR-5":[164],"strengthen":[165],"hypothesis":[167],"that":[168,233,266,288],"disease":[172],"involving":[173],"innate":[174],"immunity.":[175],"Three":[176],"are":[180],"known":[181],"to":[182,185,247],"specifically":[183],"bind":[184],"transport":[187],"protein,":[188],"albumin":[191],"(HSA).":[192],"Also,":[193],"specific":[197],"high-affinity":[199],"ligand":[200],"alpha":[202],"1":[203],"beta":[204],"glycoprotein,":[205],"which":[206],"HSA":[209,213,226,265,282,287,342],"binder.":[210],"To":[211],"investigate":[212],"binding":[214,220,235],"properties,":[215],"quantitatively":[217],"measured":[218],"dye":[223,303],"probe":[224,238],"neutral":[228],"pH.":[229],"These":[230],"measurements":[231],"revealed":[232],"HAS":[234],"correlates":[239],"several":[241],"metabolic":[242,276],"parameters":[243],"central":[245],"importance":[246],"diagnosis":[249],"T2DM,":[251],"including":[252],"fasting":[253],"glucose":[255],"(FPG).":[256],"Therefore,":[257],"this":[258],"assay":[259],"may":[260,289],"reveal":[261],"altered":[262,284],"properties":[263],"could":[267],"be":[268],"for":[270],"clinical":[272],"assessment":[273],"individuals'":[275],"status.":[277],"sought":[279],"modifications":[280],"or":[283],"cargo":[285],"cause":[290],"difference":[292],"binding.":[294],"1D":[295,318],"gels":[296],"reacted":[300,323],"maleimide":[302],"showed":[304,337],"no":[305],"changed":[306],"oxidation":[310,343],"state":[311],"HSA's":[313],"lone":[314],"thiol,":[315],"Cys-34.":[316],"However,":[317],"blots":[319],"oxidative":[326],"carbonyl":[327],"probe,":[328],"hydrazide-biotin":[329],"conjugate,":[330],"probed":[332],"luminol":[334],"reactive":[335],"HRP-neutravidin":[336],"surprising":[339],"anti-correlation":[340],"hemoglobin":[345],"A1c,":[346],"indicator":[348],"glycemic":[350],"control.":[351]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
