{"id":"https://openalex.org/W597369484","doi":null,"title":"Signal Transduction Pathways Modulated by the PD-causative Gene LRRK2","display_name":"Signal Transduction Pathways Modulated by the PD-causative Gene LRRK2","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W597369484","mag":"597369484"},"language":"en","primary_location":{"id":"mag:597369484","doi":null,"is_oa":false,"landing_page_url":"https://publikationen.uni-tuebingen.de/xmlui/bitstream/10900/44084/1/pdf/Thesis_ICC_FinalVersion.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068882014","display_name":"Iria Carballo\u2010Carbajal","orcid":"https://orcid.org/0000-0002-4403-8006","observed_orcids":["https://orcid.org/0000-0002-4403-8006"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Iria Carballo\u2010Carbajal","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4403-8006","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5068882014"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13991","display_name":"Nuclear Receptors and Signaling","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lrrk2","display_name":"LRRK2","score":0.9940000176429749},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.7879999876022339},{"id":"https://openalex.org/keywords/signaling-pathways","display_name":"signaling pathways","score":0.9440000057220459},{"id":"https://openalex.org/keywords/protein-kinases","display_name":"protein kinases","score":0.47200000286102295}],"concepts":[{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.7318885922431946},{"id":"https://openalex.org/C2780427247","wikidata":"https://www.wikidata.org/wiki/Q409961","display_name":"LRRK2","level":4,"score":0.5735580325126648},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5195541977882385},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48820334672927856},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.42376238107681274},{"id":"https://openalex.org/C15152581","wikidata":"https://www.wikidata.org/wiki/Q7833966","display_name":"Transduction (biophysics)","level":2,"score":0.41938042640686035},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.40141281485557556},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.37230706214904785},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3317224085330963},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.129866361618042},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.10910066962242126}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:597369484","doi":null,"is_oa":false,"landing_page_url":"https://publikationen.uni-tuebingen.de/xmlui/bitstream/10900/44084/1/pdf/Thesis_ICC_FinalVersion.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":124,"referenced_works":["https://openalex.org/W62603772","https://openalex.org/W168430499","https://openalex.org/W1511827873","https://openalex.org/W1521854746","https://openalex.org/W1527671059","https://openalex.org/W1550876205","https://openalex.org/W1563535780","https://openalex.org/W1572679174","https://openalex.org/W1618846043","https://openalex.org/W1877873625","https://openalex.org/W1899552864","https://openalex.org/W1900066504","https://openalex.org/W1925696976","https://openalex.org/W1967603366","https://openalex.org/W1968390598","https://openalex.org/W1968942251","https://openalex.org/W1970687029","https://openalex.org/W1970848642","https://openalex.org/W1971064755","https://openalex.org/W1975722154","https://openalex.org/W1978419085","https://openalex.org/W1980815362","https://openalex.org/W1980914717","https://openalex.org/W1983591304","https://openalex.org/W1987951773","https://openalex.org/W1990845627","https://openalex.org/W1992101582","https://openalex.org/W1992365739","https://openalex.org/W1993733276","https://openalex.org/W1996285410","https://openalex.org/W1996424480","https://openalex.org/W1997163042","https://openalex.org/W1997211840","https://openalex.org/W2003883601","https://openalex.org/W2006875797","https://openalex.org/W2011069161","https://openalex.org/W2019006980","https://openalex.org/W2021097923","https://openalex.org/W2021793835","https://openalex.org/W2021976306","https://openalex.org/W2021977313","https://openalex.org/W2031031932","https://openalex.org/W2032206743","https://openalex.org/W2032634798","https://openalex.org/W2032817175","https://openalex.org/W2034415869","https://openalex.org/W2036284461","https://openalex.org/W2037030597","https://openalex.org/W2039007685","https://openalex.org/W2042949114","https://openalex.org/W2044031210","https://openalex.org/W2044712342","https://openalex.org/W2045512818","https://openalex.org/W2046250536","https://openalex.org/W2046623850","https://openalex.org/W2050849483","https://openalex.org/W2055878844","https://openalex.org/W2055927110","https://openalex.org/W2056043640","https://openalex.org/W2058186189","https://openalex.org/W2063127941","https://openalex.org/W2066594212","https://openalex.org/W2070895853","https://openalex.org/W2072704848","https://openalex.org/W2074180389","https://openalex.org/W2074710446","https://openalex.org/W2080536654","https://openalex.org/W2082209194","https://openalex.org/W2082214510","https://openalex.org/W2082471010","https://openalex.org/W2084910880","https://openalex.org/W2085179489","https://openalex.org/W2087360216","https://openalex.org/W2089518139","https://openalex.org/W2091245304","https://openalex.org/W2091404872","https://openalex.org/W2091507010","https://openalex.org/W2095338669","https://openalex.org/W2095455369","https://openalex.org/W2095529485","https://openalex.org/W2097073373","https://openalex.org/W2098095284","https://openalex.org/W2099677820","https://openalex.org/W2100300726","https://openalex.org/W2100894616","https://openalex.org/W2102321702","https://openalex.org/W2104912043","https://openalex.org/W2105601225","https://openalex.org/W2106954135","https://openalex.org/W2111295274","https://openalex.org/W2115687796","https://openalex.org/W2116597539","https://openalex.org/W2116598203","https://openalex.org/W2119489612","https://openalex.org/W2119820377","https://openalex.org/W2120262230","https://openalex.org/W2122072833","https://openalex.org/W2123431154","https://openalex.org/W2124906403","https://openalex.org/W2125427342","https://openalex.org/W2126549314","https://openalex.org/W2128316018","https://openalex.org/W2130497877","https://openalex.org/W2131207606","https://openalex.org/W2134412560","https://openalex.org/W2134829539","https://openalex.org/W2136216054","https://openalex.org/W2136388422","https://openalex.org/W2137317629","https://openalex.org/W2137901394","https://openalex.org/W2139085451","https://openalex.org/W2139369185","https://openalex.org/W2140647923","https://openalex.org/W2142286857","https://openalex.org/W2143161560","https://openalex.org/W2144435948","https://openalex.org/W2150656456","https://openalex.org/W2154757569","https://openalex.org/W2158778370","https://openalex.org/W2160442779","https://openalex.org/W2165355919","https://openalex.org/W2169294911","https://openalex.org/W2171873547","https://openalex.org/W2992789094"],"related_works":["https://openalex.org/W2094771414","https://openalex.org/W2782386430","https://openalex.org/W2906211657","https://openalex.org/W1992101582","https://openalex.org/W2120190828","https://openalex.org/W2017708065","https://openalex.org/W7100239817","https://openalex.org/W2306800765","https://openalex.org/W2900705295","https://openalex.org/W7098874618"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}