{"id":"https://openalex.org/W596065307","doi":null,"title":"Effectiveness and costs of new medical technologies : register-based research in psoriasis","display_name":"Effectiveness and costs of new medical technologies : register-based research in psoriasis","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W596065307","mag":"596065307"},"language":"en","primary_location":{"id":"pmh:oai:DiVA.org:umu-81899","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81899","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81899","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068063454","display_name":"Jenny M. Norlin","orcid":"https://orcid.org/0000-0001-5402-1884","observed_orcids":["https://orcid.org/0000-0001-5402-1884"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jenny M. Norlin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5402-1884","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5068063454"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.9829000234603882,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.015200000256299973,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11092","display_name":"Spondyloarthritis Studies and Treatments","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/psoriasis","display_name":"psoriasis","score":0.9449999928474426},{"id":"https://openalex.org/keywords/biologics","display_name":"biologics","score":0.8399999737739563},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.9570000171661377},{"id":"https://openalex.org/keywords/eq-5d","display_name":"EQ-5D","score":0.972000002861023},{"id":"https://openalex.org/keywords/dermatology-life-quality-index","display_name":"Dermatology Life Quality Index","score":0.9409999847412109},{"id":"https://openalex.org/keywords/psoriasis-area-and-severity-index","display_name":"Psoriasis Area and Severity Index","score":0.9179999828338623},{"id":"https://openalex.org/keywords/treatment-effectiveness","display_name":"treatment effectiveness","score":0.5759999752044678},{"id":"https://openalex.org/keywords/cost-analysis","display_name":"cost analysis","score":0.4169999957084656},{"id":"https://openalex.org/keywords/productivity-loss","display_name":"productivity loss","score":0.7250000238418579},{"id":"https://openalex.org/keywords/sick-leave","display_name":"sick leave","score":0.8960000276565552},{"id":"https://openalex.org/keywords/disability-pension","display_name":"disability pension","score":0.9279999732971191},{"id":"https://openalex.org/keywords/propensity-score-matching","display_name":"propensity score matching","score":0.7289999723434448},{"id":"https://openalex.org/keywords/treatment-switching","display_name":"treatment switching","score":0.3889999985694885},{"id":"https://openalex.org/keywords/sweden","display_name":"Sweden","score":0.3160000145435333},{"id":"https://openalex.org/keywords/administrative-records","display_name":"administrative records","score":0.4339999854564667},{"id":"https://openalex.org/keywords/calcipotriol","display_name":"calcipotriol","score":0.6890000104904175}],"concepts":[{"id":"https://openalex.org/C2779235478","wikidata":"https://www.wikidata.org/wiki/Q286576","display_name":"Register (sociolinguistics)","level":2,"score":0.8302669525146484},{"id":"https://openalex.org/C2780564577","wikidata":"https://www.wikidata.org/wiki/Q179945","display_name":"Psoriasis","level":2,"score":0.5005600452423096},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4558478891849518},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.39761513471603394},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34614408016204834},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.1406952142715454},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:DiVA.org:umu-81899","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81899","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:596065307","doi":null,"is_oa":false,"landing_page_url":"http://umu.diva-portal.org/smash/get/diva2:658776/FULLTEXT01.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:DiVA.org:umu-81899","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-81899","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":129,"referenced_works":["https://openalex.org/W6525474","https://openalex.org/W68080589","https://openalex.org/W174864538","https://openalex.org/W305821957","https://openalex.org/W386602625","https://openalex.org/W1521578484","https://openalex.org/W1539664312","https://openalex.org/W1541913191","https://openalex.org/W1586104616","https://openalex.org/W1591707453","https://openalex.org/W1594294799","https://openalex.org/W1595046345","https://openalex.org/W1683131358","https://openalex.org/W1830132041","https://openalex.org/W1890063097","https://openalex.org/W1960852816","https://openalex.org/W1969387970","https://openalex.org/W1970374211","https://openalex.org/W1974487733","https://openalex.org/W1979202959","https://openalex.org/W1980088055","https://openalex.org/W1980509189","https://openalex.org/W1980773105","https://openalex.org/W1980906371","https://openalex.org/W1982340783","https://openalex.org/W1982657905","https://openalex.org/W1983185705","https://openalex.org/W1984598192","https://openalex.org/W1984704099","https://openalex.org/W1985951317","https://openalex.org/W1986356530","https://openalex.org/W1990174229","https://openalex.org/W1993007780","https://openalex.org/W1993434356","https://openalex.org/W1994127723","https://openalex.org/W1994222210","https://openalex.org/W1995437285","https://openalex.org/W1996308907","https://openalex.org/W2012581664","https://openalex.org/W2013884649","https://openalex.org/W2015169835","https://openalex.org/W2020465926","https://openalex.org/W2022665587","https://openalex.org/W2023626281","https://openalex.org/W2028535337","https://openalex.org/W2028988552","https://openalex.org/W2030348118","https://openalex.org/W2032644680","https://openalex.org/W2038553797","https://openalex.org/W2038741370","https://openalex.org/W2039342460","https://openalex.org/W2039459572","https://openalex.org/W2043105813","https://openalex.org/W2051454087","https://openalex.org/W2056468769","https://openalex.org/W2057673947","https://openalex.org/W2062348457","https://openalex.org/W2062964437","https://openalex.org/W2065290004","https://openalex.org/W2067327580","https://openalex.org/W2068847846","https://openalex.org/W2070187660","https://openalex.org/W2074479676","https://openalex.org/W2077105946","https://openalex.org/W2077521143","https://openalex.org/W2077931585","https://openalex.org/W2078018971","https://openalex.org/W2080165152","https://openalex.org/W2087604552","https://openalex.org/W2087624875","https://openalex.org/W2089881590","https://openalex.org/W2092044092","https://openalex.org/W2093116261","https://openalex.org/W2095297002","https://openalex.org/W2096922379","https://openalex.org/W2096991001","https://openalex.org/W2097896724","https://openalex.org/W2100130506","https://openalex.org/W2102350540","https://openalex.org/W2110888991","https://openalex.org/W2111469026","https://openalex.org/W2112639571","https://openalex.org/W2115793908","https://openalex.org/W2116956799","https://openalex.org/W2119275077","https://openalex.org/W2121255135","https://openalex.org/W2121797973","https://openalex.org/W2122294114","https://openalex.org/W2122897116","https://openalex.org/W2124446884","https://openalex.org/W2127557926","https://openalex.org/W2127742687","https://openalex.org/W2128700736","https://openalex.org/W2130212511","https://openalex.org/W2130267399","https://openalex.org/W2133542467","https://openalex.org/W2133696182","https://openalex.org/W2134233465","https://openalex.org/W2138914922","https://openalex.org/W2139140379","https://openalex.org/W2142296697","https://openalex.org/W2147064041","https://openalex.org/W2149566497","https://openalex.org/W2150291618","https://openalex.org/W2152262899","https://openalex.org/W2153012086","https://openalex.org/W2153113150","https://openalex.org/W2153434255","https://openalex.org/W2154375899","https://openalex.org/W2154432417","https://openalex.org/W2155734838","https://openalex.org/W2157450846","https://openalex.org/W2159805452","https://openalex.org/W2163232748","https://openalex.org/W2165311713","https://openalex.org/W2165657093","https://openalex.org/W2165687042","https://openalex.org/W2166811019","https://openalex.org/W2168698481","https://openalex.org/W2168924589","https://openalex.org/W2333929093","https://openalex.org/W2409131213","https://openalex.org/W2419288916","https://openalex.org/W2432281636","https://openalex.org/W2473786944","https://openalex.org/W2556753265","https://openalex.org/W2568854734","https://openalex.org/W2891753394","https://openalex.org/W3124120302"],"related_works":["https://openalex.org/W162023131","https://openalex.org/W2212402863","https://openalex.org/W4230502996","https://openalex.org/W2001283734","https://openalex.org/W2572784991","https://openalex.org/W2117064660","https://openalex.org/W2024814916","https://openalex.org/W2511213882","https://openalex.org/W2056733295","https://openalex.org/W2125574991"],"abstract_inverted_index":{"Psoriasis":[0,16,163,619],"is":[1,17,620],"a":[2,131,214,321,324,334,342,347,508,592,632],"chronic,":[3],"immunological":[4],"and":[5,33,76,95,120,156,165,200,230,235,243,285,300,314,366,379,395,413,418,435,485,546,588,614,626,629,642,653,670,683],"systemic":[6,42,126,697],"disease":[7,22],"with":[8,19,35,51,197,251,270,282,345,444,497,550,583,623,705],"an":[9],"estimated":[10,292,399,423],"prevalence":[11],"of":[12,61,73,87,100,108,128,160,249,255,297,312,323,341,392,537,566,577,608,696],"about":[13,645],"2-3":[14],"percent.":[15],"associated":[18,621],"the":[20,67,85,101,106,122,136,140,145,150,157,187,218,239,252,295,309,328,337,351,375,380,410,428,456,486,498,526,534,538,605,693],"joint":[21],"psoriasis":[23,32,39,55,81,90,102,178,274,325,353,371,448,532,554,584,640,706],"arthropathy.":[24],"There":[25],"are":[26,656,678,699],"several":[27],"treatments":[28,641,677,698],"options":[29],"available":[30],"for":[31,49,125,186,217,370,432,528],"patients":[34,50,179,207,269,330,377,549,567,704],"moderate":[36,52,271,445,490,529,551],"to":[37,53,65,83,96,182,213,259,264,272,404,446,507,530,552,570,591,661],"severe":[38,54,273,447,473,531,553],"generally":[40],"need":[41],"agents.":[43],"In":[44,130],"2004":[45],"biologics":[46,88,109,265],"were":[47,169,195,232,280,289,294,303,407,555],"introduced":[48],"in":[56,80,89,91,110,190,209,238,244,268,278,305,327,336,362,390,453,513,518,558,707],"Sweden.":[57,111,191,441],"The":[58,174,225,246,291,481,543,564],"overall":[59,240],"objective":[60],"this":[62],"thesis":[63],"was":[64,114,180,266,422],"assess":[66],"relationship":[68],"between":[69,193,612],"Health":[70,313],"Related":[71],"Quality":[72,153],"Life":[74,152],"(HRQOL)":[75],"clinical":[77,93,158,474,499,654,709],"outcome":[78,138],"measures":[79,194,655],"patients,":[82],"analyse":[84],"effectiveness":[86,248],"everyday":[92],"practice":[94],"explore":[97],"how":[98],"costs":[99,358,386,402,602,607,625],"population":[103,189,412,458],"changed":[104],"after":[105,236],"introduction":[107],"Methods:":[112],"Research":[113],"based":[115,424],"on":[116,415,425,635,666],"national":[117,306,329,376],"administrative":[118],"registers":[119,307],"PsoReg,":[121],"Swedish":[123,708],"registry":[124],"treatment":[127,257,287,344,572,646],"psoriasis.":[129],"cross-sectional":[132],"study":[133,205],"(paper":[134,223,275,355,459,479,502,521,541,562,580,599,616],"I)":[135],"three":[137,226],"measures:":[139],"generic":[141,175,482],"HRQOL":[142,148,452,464,651],"measure":[143,149,159,483,500],"EQ-5D,":[144,228,298],"dermatology":[146],"specific":[147],"Dermatology":[151],"Index":[154,167],"(DLQI)":[155],"skin":[161,475],"involvement,":[162],"Area":[164],"Severity":[166],"(PASI),":[168],"analysed":[170,233,267],"by":[171,320,333],"demographic":[172],"characteristics.":[173],"EQ-5D":[176,454,484,493],"among":[177,703],"compared":[181,258,403],"previously":[183],"published":[184],"values":[185],"general":[188,457],"Relationships":[192],"examined":[196],"correlation":[198,496],"tests":[199],"regression":[201],"analysis.":[202],"A":[203],"longitudinal":[204],"included":[206,359,387],"registered":[208],"PsoReg":[210,279,514],"who":[211,505,524],"switched":[212,506],"biologic":[215,509,539,578,684],"agent":[216,510],"first":[219,681],"time":[220],"during":[221,511],"registration":[222,322,335,512],"II).":[224,522,542],"outcomes":[227,293,520],"DLQI,":[229,299],"PASI":[231,501],"before":[234],"switch":[237],"patient":[241],"group":[242],"subgroups.":[245],"relative":[247],"continuing":[250],"standard":[253,262],"care":[254,263,365],"conventional":[256,571,676],"switching":[260],"from":[261,374,409,427],"III).":[276,563,581],"Patients":[277,302,443,504,523],"matched":[281,414,544,597],"propensity":[283],"scores":[284],"average":[286],"effects":[288],"estimated.":[290],"change":[296],"PASI.":[301],"identified":[304],"at":[308,439],"National":[310],"Board":[311],"Welfare":[315],"when":[316],"analysing":[317],"costs;":[318],"either":[319],"diagnosis":[326],"register":[331,340,378],"and/or":[332],"prescribed":[338,367,381],"drugs":[339,368,382],"topical":[343],"calcipotriol,":[346],"substance":[348],"which":[349,398],"has":[350,631],"indication":[352],"only":[354],"IV).":[356,600,617],"Direct":[357,601],"patients\u2019":[360,636],"visits":[361],"specialist":[363],"health":[364,433],"used":[369],"treatment,":[372],"retrieved":[373],"register,":[383],"respectively.":[384],"Indirect":[385],"productivity":[388,609],"loss":[389,421,610],"terms":[391],"sick":[393,586],"leave":[394,587],"disability":[396,589],"pension,":[397],"as":[400,658,680,686],"excess":[401],"controls.":[405],"Controls":[406],"selected":[408],"normal":[411],"sex,":[416],"age":[417],"municipality.":[419],"Productivity":[420],"data":[426,667],"Longitudinal":[429],"integration":[430],"database":[431],"insurance":[434],"labour":[436],"market":[437],"studies":[438],"Statistics":[440],"Results:":[442],"had":[449,471,489,494,515,533,573,585],"significantly":[450],"lower":[451,465],"than":[455,466,477,595],"I).":[460,480,503],"Women":[461],"rated":[462],"their":[463,596],"men,":[467],"even":[468],"though":[469],"men":[470],"more":[472],"involvement":[476],"women.":[478],"dermatology-specific":[487,650],"DLQI":[488],"correlations":[491],"whereas":[492,604],"low":[495],"significant":[516],"improvements":[517],"all":[519],"fulfilled":[525],"criteria":[527],"highest":[535],"benefits":[536,576],"agents":[540,579,685],"conventionally":[545],"biologically":[547],"treated":[548],"essentially":[556],"equal":[557],"important":[559],"observable":[560],"variables":[561],"subgroup":[565],"not":[568,700],"responding":[569],"high":[574],"potential":[575],"Individuals":[582],"pension":[590],"larger":[593],"extent":[594],"controls":[598],"increased,":[603],"indirect":[606,627],"decreased":[611],"2006":[613],"2009":[615],"Conclusion:":[618],"both":[622,648],"direct":[624],"costs,":[628],"it":[630],"negative":[633],"impact":[634],"HRQOL.":[637],"When":[638],"evaluating":[639],"making":[643],"decisions":[644],"guidelines,":[647],"generic,":[649],"measures,":[652],"necessary;":[657],"they":[659],"answer":[660],"different":[662,694],"needs.":[663],"Although":[664],"dependent":[665],"quality,":[668],"generalisability,":[669],"current":[671],"pricing,":[672],"results":[673],"suggest":[674],"that":[675,692],"suitable":[679],"line":[682,688],"second":[687],"treatment.":[689],"Results":[690],"indicate":[691],"types":[695],"allocated":[701],"optimally":[702],"practice.":[710]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
