{"id":"https://openalex.org/W593178148","doi":"https://doi.org/10.1002/9783527621095.ch11","title":"System Analysis of Cardiac Energetics\u2013Excitation\u2013Contraction Coupling: Integration of Mitochondrial Respiration, Phosphotransfer Pathways, Metabolic Pacing, and Substrate Supply in the Heart","display_name":"System Analysis of Cardiac Energetics\u2013Excitation\u2013Contraction Coupling: Integration of Mitochondrial Respiration, Phosphotransfer Pathways, Metabolic Pacing, and Substrate Supply in the Heart","publication_year":2007,"publication_date":"2007-09-19","ids":{"openalex":"https://openalex.org/W593178148","doi":"https://doi.org/10.1002/9783527621095.ch11","mag":"593178148"},"language":"en","primary_location":{"id":"doi:10.1002/9783527621095.ch11","doi":"https://doi.org/10.1002/9783527621095.ch11","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9783527621095.ch11","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular System Bioenergetics","raw_type":"other"},"volume":{"id":"https://openalex.org/W2488739750","display_name":"Molecular System Bioenergetics"},"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002203819","display_name":"Valdur A. Saks","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177483745","display_name":"Universit\u00e9 Joseph Fourier","ror":"https://ror.org/02aj0kh94","country_code":"FR","type":"education","lineage":["https://openalex.org/I177483745","https://openalex.org/I899635006"]},{"id":"https://openalex.org/I31528381","display_name":"National Institute of Chemical Physics and Biophysics","ror":"https://ror.org/03eqd4a41","country_code":"EE","type":"facility","lineage":["https://openalex.org/I31528381"]},{"id":"https://openalex.org/I4210153067","display_name":"Laboratory of Fundamental and Applied Bioenergetics","ror":"https://ror.org/05514hp74","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210139971","https://openalex.org/I4210150872","https://openalex.org/I4210153067","https://openalex.org/I899635006"]}],"countries":["EE","FR"],"is_corresponding":false,"raw_author_name":"Valdur Saks","raw_affiliation_strings":["J. Fourier University, Laboratory of Bioenergetics, 2280 rue de la Piscine, 38041 Grenoble Cedex 9, France","National Institute of Chemical and Biological Physics, Laboratory of Bioenergetics, Akadeemia tee 23, 12618 Tallinn, Estonia","Universite\u0301 Joseph Fourier, Bioe\u0301nerge\u0301tique Fondamentale et Applique\u0301e, INSERM U884, BP 53X, 38041 Grenoble Cedex, France","Universit\u00e9 Joseph Fourier, Bio\u00e9nerg\u00e9tique Fondamentale et Appliqu\u00e9e, INSERM U884, BP 53X, 38041 Grenoble Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"J. Fourier University, Laboratory of Bioenergetics, 2280 rue de la Piscine, 38041 Grenoble Cedex 9, France","institution_ids":["https://openalex.org/I177483745"]},{"raw_affiliation_string":"National Institute of Chemical and Biological Physics, Laboratory of Bioenergetics, Akadeemia tee 23, 12618 Tallinn, Estonia","institution_ids":["https://openalex.org/I31528381"]},{"raw_affiliation_string":"Universite\u0301 Joseph Fourier, Bioe\u0301nerge\u0301tique Fondamentale et Applique\u0301e, INSERM U884, BP 53X, 38041 Grenoble Cedex, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177483745","https://openalex.org/I4210153067"]},{"raw_affiliation_string":"Universit\u00e9 Joseph Fourier, Bio\u00e9nerg\u00e9tique Fondamentale et Appliqu\u00e9e, INSERM U884, BP 53X, 38041 Grenoble Cedex, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177483745","https://openalex.org/I4210153067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042727507","display_name":"Petras P. Dzeja","orcid":"https://orcid.org/0000-0002-7014-9930","observed_orcids":["https://orcid.org/0000-0002-7014-9930"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Petras P. Dzeja","raw_affiliation_strings":["Mayo Clinic College of Medicine, Departments of Medicine, Molecular Pharmacology, and Experimental Therapeutics, Division of Cardiovascular Diseases, 200 First Street SW, Rochester, MN 559095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic College of Medicine, Departments of Medicine, Molecular Pharmacology, and Experimental Therapeutics, Division of Cardiovascular Diseases, 200 First Street SW, Rochester, MN 559095, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062748939","display_name":"Rita Guzun","orcid":"https://orcid.org/0000-0001-9838-0010","observed_orcids":["https://orcid.org/0000-0001-9838-0010"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I177483745","display_name":"Universit\u00e9 Joseph Fourier","ror":"https://ror.org/02aj0kh94","country_code":"FR","type":"education","lineage":["https://openalex.org/I177483745","https://openalex.org/I899635006"]},{"id":"https://openalex.org/I4210153067","display_name":"Laboratory of Fundamental and Applied Bioenergetics","ror":"https://ror.org/05514hp74","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210139971","https://openalex.org/I4210150872","https://openalex.org/I4210153067","https://openalex.org/I899635006"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Rita Guzun","raw_affiliation_strings":["Universite\u0301 Joseph Fourier, Bioe\u0301nerge\u0301tique Fondamentale et Applique\u0301e, INSERM U884, BP 53X, 38041 Grenoble Cedex, France","Universit\u00e9 Joseph Fourier, Bio\u00e9nerg\u00e9tique Fondamentale et Appliqu\u00e9e, INSERM U884, BP 53X, 38041 Grenoble Cedex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universite\u0301 Joseph Fourier, Bioe\u0301nerge\u0301tique Fondamentale et Applique\u0301e, INSERM U884, BP 53X, 38041 Grenoble Cedex, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177483745","https://openalex.org/I4210153067"]},{"raw_affiliation_string":"Universit\u00e9 Joseph Fourier, Bio\u00e9nerg\u00e9tique Fondamentale et Appliqu\u00e9e, INSERM U884, BP 53X, 38041 Grenoble Cedex, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I177483745","https://openalex.org/I4210153067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052482364","display_name":"Mayis Aliev","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210089595","display_name":"Institute of Experimental Cardiology","ror":"https://ror.org/00bw4xw30","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1318325419","https://openalex.org/I4210089595"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Mayis K. Aliev","raw_affiliation_strings":["Cardiology Research Center, Institute of Experimental Cardiology, Laboratory of Cardiac Pathology, 3rd Cherepkovskaya Street 15A, 121552 Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology Research Center, Institute of Experimental Cardiology, Laboratory of Cardiac Pathology, 3rd Cherepkovskaya Street 15A, 121552 Moscow, Russia","institution_ids":["https://openalex.org/I4210089595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029224152","display_name":"Marko Vendelin","orcid":"https://orcid.org/0000-0002-6459-0391","observed_orcids":["https://orcid.org/0000-0002-6459-0391"]},"institutions":[{"id":"https://openalex.org/I111112146","display_name":"Tallinn University of Technology","ror":"https://ror.org/0443cwa12","country_code":"EE","type":"education","lineage":["https://openalex.org/I111112146"]}],"countries":["EE"],"is_corresponding":false,"raw_author_name":"Marko Vendelin","raw_affiliation_strings":["Tallinn University of Technology, Institute of Cybernetics, Laboratory of Systems Biology, Centre for Nonlinear Studies, Akadeemia tee 21, 12618 Tallinn, Estonia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tallinn University of Technology, Institute of Cybernetics, Laboratory of Systems Biology, Centre for Nonlinear Studies, Akadeemia tee 21, 12618 Tallinn, Estonia","institution_ids":["https://openalex.org/I111112146"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047902810","display_name":"Andr\u00e9 Terzic","orcid":"https://orcid.org/0000-0001-9210-009X","observed_orcids":["https://orcid.org/0000-0001-9210-009X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andr\u00e9 Terzic","raw_affiliation_strings":["Mayo Clinic College of Medicine, Departments of Medicine, Medicinal Genetics, Molecular Pharmacology, and Experimental Therapeutics, 200 First Street SW, Rochester, MN 559095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic College of Medicine, Departments of Medicine, Medicinal Genetics, Molecular Pharmacology, and Experimental Therapeutics, 200 First Street SW, Rochester, MN 559095, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020744253","display_name":"Theo Wallimann","orcid":"https://orcid.org/0000-0003-4957-5836","observed_orcids":["https://orcid.org/0000-0003-4957-5836"]},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Theo Wallimann","raw_affiliation_strings":["ETH Zurich, Hoenggerberg, Institute of Cell Biology, HPM-D24, Schafmattstrasse 18, 8093 Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ETH Zurich, Hoenggerberg, Institute of Cell Biology, HPM-D24, Schafmattstrasse 18, 8093 Zurich, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":8,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"367","last_page":"405"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.03060000017285347,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.015399999916553497,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiac-energetics","display_name":"cardiac energetics","score":0.972000002861023},{"id":"https://openalex.org/keywords/excitation-contraction-coupling","display_name":"excitation-contraction coupling","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mitochondrial-respiration","display_name":"mitochondrial respiration","score":0.8709999918937683},{"id":"https://openalex.org/keywords/substrate-supply","display_name":"substrate supply","score":0.6269999742507935},{"id":"https://openalex.org/keywords/frank-starling-mechanism","display_name":"Frank-Starling mechanism","score":0.8550000190734863},{"id":"https://openalex.org/keywords/calcium-metabolism","display_name":"calcium metabolism","score":0.6520000100135803},{"id":"https://openalex.org/keywords/length-dependent-activation","display_name":"length-dependent activation","score":0.6790000200271606},{"id":"https://openalex.org/keywords/mitochondrial-creatine-kinase","display_name":"mitochondrial creatine kinase","score":0.7480000257492065},{"id":"https://openalex.org/keywords/metabolic-channeling","display_name":"metabolic channeling","score":0.7860000133514404},{"id":"https://openalex.org/keywords/calcium-overload","display_name":"calcium overload","score":0.8579999804496765},{"id":"https://openalex.org/keywords/free-radicals","display_name":"free radicals","score":0.8569999933242798},{"id":"https://openalex.org/keywords/fatty-acid-oxidation","display_name":"fatty acid oxidation","score":0.9890000224113464},{"id":"https://openalex.org/keywords/glucose-oxidation","display_name":"glucose oxidation","score":0.9919999837875366},{"id":"https://openalex.org/keywords/energy-homeostasis","display_name":"energy homeostasis","score":0.8050000071525574},{"id":"https://openalex.org/keywords/metabolic-modeling","display_name":"metabolic modeling","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.5376120805740356},{"id":"https://openalex.org/C114908165","wikidata":"https://www.wikidata.org/wiki/Q127006","display_name":"Excitation\u2013contraction coupling","level":3,"score":0.5096666812896729},{"id":"https://openalex.org/C163415756","wikidata":"https://www.wikidata.org/wiki/Q126473","display_name":"Contraction (grammar)","level":2,"score":0.4777756929397583},{"id":"https://openalex.org/C6929976","wikidata":"https://www.wikidata.org/wiki/Q3771881","display_name":"Regulator","level":3,"score":0.4715452492237091},{"id":"https://openalex.org/C97514900","wikidata":"https://www.wikidata.org/wiki/Q719597","display_name":"Energetics","level":2,"score":0.46824944019317627},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.4653953015804291},{"id":"https://openalex.org/C201571599","wikidata":"https://www.wikidata.org/wiki/Q5018840","display_name":"Calcium signaling","level":3,"score":0.45552241802215576},{"id":"https://openalex.org/C192989942","wikidata":"https://www.wikidata.org/wiki/Q68685","display_name":"Metabolic pathway","level":3,"score":0.44499480724334717},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.44247111678123474},{"id":"https://openalex.org/C2991704936","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Cell metabolism","level":3,"score":0.44083619117736816},{"id":"https://openalex.org/C2491326","wikidata":"https://www.wikidata.org/wiki/Q5377024","display_name":"Energy homeostasis","level":3,"score":0.43646371364593506},{"id":"https://openalex.org/C66517615","wikidata":"https://www.wikidata.org/wiki/Q912751","display_name":"Cellular respiration","level":3,"score":0.426257461309433},{"id":"https://openalex.org/C182215343","wikidata":"https://www.wikidata.org/wiki/Q472287","display_name":"Respiration","level":2,"score":0.4235912263393402},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4176065921783447},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.41012144088745117},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3962308466434479},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3927680253982544},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.3908161520957947},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3045106530189514},{"id":"https://openalex.org/C207200792","wikidata":"https://www.wikidata.org/wiki/Q428914","display_name":"Myocyte","level":2,"score":0.2735135853290558},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.26118698716163635},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.22997775673866272},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.13638636469841003},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.13437595963478088},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10741010308265686},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9783527621095.ch11","doi":"https://doi.org/10.1002/9783527621095.ch11","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9783527621095.ch11","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular System Bioenergetics","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":179,"referenced_works":["https://openalex.org/W46974184","https://openalex.org/W89761545","https://openalex.org/W162990493","https://openalex.org/W971805670","https://openalex.org/W1485297825","https://openalex.org/W1500554454","https://openalex.org/W1509512816","https://openalex.org/W1542197083","https://openalex.org/W1544106935","https://openalex.org/W1554653315","https://openalex.org/W1556440714","https://openalex.org/W1572887479","https://openalex.org/W1573788449","https://openalex.org/W1580659904","https://openalex.org/W1581839454","https://openalex.org/W1583314060","https://openalex.org/W1590662964","https://openalex.org/W1596258111","https://openalex.org/W1601936385","https://openalex.org/W1666357690","https://openalex.org/W1697383903","https://openalex.org/W1749560786","https://openalex.org/W1756031092","https://openalex.org/W1765746982","https://openalex.org/W1849159432","https://openalex.org/W1861099352","https://openalex.org/W1901823973","https://openalex.org/W1920479129","https://openalex.org/W1935060748","https://openalex.org/W1944999268","https://openalex.org/W1949811505","https://openalex.org/W1964430604","https://openalex.org/W1969076555","https://openalex.org/W1970205234","https://openalex.org/W1971754858","https://openalex.org/W1971973726","https://openalex.org/W1976568495","https://openalex.org/W1976701283","https://openalex.org/W1978278112","https://openalex.org/W1981502020","https://openalex.org/W1981967975","https://openalex.org/W1986124091","https://openalex.org/W1987584482","https://openalex.org/W1990811092","https://openalex.org/W1992201093","https://openalex.org/W1992684611","https://openalex.org/W1993035984","https://openalex.org/W1994147843","https://openalex.org/W1995111069","https://openalex.org/W1996632254","https://openalex.org/W2004207598","https://openalex.org/W2004655740","https://openalex.org/W2005861308","https://openalex.org/W2005892557","https://openalex.org/W2007189231","https://openalex.org/W2007545368","https://openalex.org/W2007596664","https://openalex.org/W2010670898","https://openalex.org/W2014167033","https://openalex.org/W2017342497","https://openalex.org/W2018045523","https://openalex.org/W2027619968","https://openalex.org/W2028946095","https://openalex.org/W2029621593","https://openalex.org/W2030150795","https://openalex.org/W2030667970","https://openalex.org/W2031144191","https://openalex.org/W2031644336","https://openalex.org/W2032161405","https://openalex.org/W2032282106","https://openalex.org/W2037361270","https://openalex.org/W2039405238","https://openalex.org/W2041492137","https://openalex.org/W2044629144","https://openalex.org/W2044726034","https://openalex.org/W2046145680","https://openalex.org/W2046196975","https://openalex.org/W2047399305","https://openalex.org/W2049153018","https://openalex.org/W2049187114","https://openalex.org/W2049251974","https://openalex.org/W2050824263","https://openalex.org/W2051363468","https://openalex.org/W2058820871","https://openalex.org/W2060617902","https://openalex.org/W2062324569","https://openalex.org/W2064766307","https://openalex.org/W2066407509","https://openalex.org/W2067066123","https://openalex.org/W2068048197","https://openalex.org/W2068089024","https://openalex.org/W2068722248","https://openalex.org/W2070266339","https://openalex.org/W2071518542","https://openalex.org/W2072334737","https://openalex.org/W2072985278","https://openalex.org/W2076802214","https://openalex.org/W2077410583","https://openalex.org/W2078132151","https://openalex.org/W2078848135","https://openalex.org/W2081017803","https://openalex.org/W2082159651","https://openalex.org/W2085754322","https://openalex.org/W2086675887","https://openalex.org/W2089319455","https://openalex.org/W2091776886","https://openalex.org/W2093018084","https://openalex.org/W2094247127","https://openalex.org/W2094344877","https://openalex.org/W2095488878","https://openalex.org/W2095741248","https://openalex.org/W2097110677","https://openalex.org/W2097363242","https://openalex.org/W2099024685","https://openalex.org/W2102780353","https://openalex.org/W2103624248","https://openalex.org/W2104465251","https://openalex.org/W2109087912","https://openalex.org/W2109453695","https://openalex.org/W2111350784","https://openalex.org/W2111953301","https://openalex.org/W2117975528","https://openalex.org/W2124507273","https://openalex.org/W2126652340","https://openalex.org/W2130513658","https://openalex.org/W2131359600","https://openalex.org/W2131884110","https://openalex.org/W2134017403","https://openalex.org/W2134506141","https://openalex.org/W2135116761","https://openalex.org/W2137186514","https://openalex.org/W2137189992","https://openalex.org/W2140604902","https://openalex.org/W2141104999","https://openalex.org/W2141188578","https://openalex.org/W2141473099","https://openalex.org/W2142003218","https://openalex.org/W2144851914","https://openalex.org/W2145094126","https://openalex.org/W2146152538","https://openalex.org/W2148614114","https://openalex.org/W2150171020","https://openalex.org/W2150342902","https://openalex.org/W2150994390","https://openalex.org/W2151910388","https://openalex.org/W2153087095","https://openalex.org/W2153819921","https://openalex.org/W2154658595","https://openalex.org/W2154965092","https://openalex.org/W2155543505","https://openalex.org/W2157193327","https://openalex.org/W2158330490","https://openalex.org/W2161321266","https://openalex.org/W2162234541","https://openalex.org/W2163480486","https://openalex.org/W2165449825","https://openalex.org/W2168161582","https://openalex.org/W2169288708","https://openalex.org/W2169469988","https://openalex.org/W2170155462","https://openalex.org/W2171973622","https://openalex.org/W2178313645","https://openalex.org/W2178930977","https://openalex.org/W2186893608","https://openalex.org/W2214334965","https://openalex.org/W2281889878","https://openalex.org/W2281997396","https://openalex.org/W2338771681","https://openalex.org/W2401100369","https://openalex.org/W2413461766","https://openalex.org/W2462415355","https://openalex.org/W2470054393","https://openalex.org/W3093453526","https://openalex.org/W3188953042","https://openalex.org/W3196596234","https://openalex.org/W4246778745","https://openalex.org/W4252878270","https://openalex.org/W4254506477","https://openalex.org/W4293179290"],"related_works":["https://openalex.org/W1944999268","https://openalex.org/W1964430604","https://openalex.org/W2145094126","https://openalex.org/W4298230170","https://openalex.org/W4242411876","https://openalex.org/W2911948132","https://openalex.org/W4389449110","https://openalex.org/W2072060389","https://openalex.org/W2076802214","https://openalex.org/W2122046060"],"abstract_inverted_index":{"This":[0],"chapter":[1],"contains":[2],"sections":[3],"titled:":[4],"Abstract":[5],"Introduction":[6],"Cardiac":[7],"Energetics:":[8],"The":[9,23],"Frank-Starling":[10],"Law":[11],"and":[12,18,34,72,95,111,116],"Its":[13],"Metabolic":[14,64,78],"Aspects":[15],"Excitation\u2013Contraction":[16,21],"Coupling":[17,22],"Calcium":[19,25,93],"Metabolism":[20],"Mitochondrial":[24],"Cycle":[26],"Length-dependent":[27],"Activation":[28],"of":[29,39,47,63,70,84,92,97,103,106,108],"Contractile":[30],"System":[31,101],"Integrated":[32,104],"Phosphotransfer":[33],"Signaling":[35],"Networks":[36],"in":[37,49,52,55],"Regulation":[38,51,66,107],"Cellular":[40],"Energy":[41,76],"Homeostasis":[42],"Evidence":[43,60],"for":[44,82],"the":[45,85],"Role":[46],"MtCK":[48],"Respiration":[50],"Permeabilized":[53],"Cells":[54],"Situ":[56],"In":[57],"Vivo":[58],"Kinetic":[59],"Mathematical":[61],"Modeling":[62],"Feedback":[65],"\u201cMetabolic":[67],"Pacing\u201d:":[68],"Synchronization":[69],"Electrical":[71],"Mechanical":[73],"Activities":[74],"With":[75],"Supply":[77],"Channeling":[79],"Is":[80],"Needed":[81],"Protection":[83],"Cell":[86],"from":[87],"Functional":[88],"Failure,":[89],"Deleterious":[90],"Effects":[91],"Overload,":[94],"Overproduction":[96],"Free":[98],"Radicals":[99],"Molecular":[100],"Analysis":[102],"Mechanisms":[105],"Fatty":[109],"Acid":[110],"Glucose":[112],"Oxidation":[113],"Concluding":[114],"Remarks":[115],"Future":[117],"Directions":[118],"References":[119]},"counts_by_year":[{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}
