{"id":"https://openalex.org/W59302286","doi":null,"title":"Social habituation and dishabituation in CD-1 mice treated with the norepinephrine neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4)","display_name":"Social habituation and dishabituation in CD-1 mice treated with the norepinephrine neurotoxin N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4)","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W59302286","mag":"59302286"},"language":"en","primary_location":{"id":"pmh:oai:surface.syr.edu:psy_etd-1093","doi":null,"is_oa":false,"landing_page_url":"http://libezproxy.syr.edu/login?url=http://proquest.umi.com/pqdweb?did=732925681&sid=1&Fmt=2&clientId=3739&RQT=309&VName=PQD","pdf_url":null,"source":{"id":"https://openalex.org/S4306401700","display_name":"Syracuse University Libraries (Syracuse University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I70983195","host_organization_name":"Syracuse University","host_organization_lineage":["https://openalex.org/I70983195"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Psychology - Dissertations","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018288893","display_name":"Hewlet G. McFarlane","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Hewlet G. McFarlane","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5018288893"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00273117,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.7782999873161316,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.7782999873161316,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.0731000006198883,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11541","display_name":"Neuroendocrine regulation and behavior","score":0.06729999929666519,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/norepinephrine","display_name":"norepinephrine","score":0.8190000057220459},{"id":"https://openalex.org/keywords/dsp-4","display_name":"DSP-4","score":0.8889999985694885},{"id":"https://openalex.org/keywords/dishabituation","display_name":"dishabituation","score":0.968999981880188},{"id":"https://openalex.org/keywords/olfactory-preference","display_name":"odor preference","score":0.6570000052452087},{"id":"https://openalex.org/keywords/anosmia","display_name":"anosmia","score":0.6370000243186951},{"id":"https://openalex.org/keywords/cd-1-mice","display_name":"ICR mice","score":0.890999972820282}],"concepts":[{"id":"https://openalex.org/C2780358027","wikidata":"https://www.wikidata.org/wiki/Q407752","display_name":"Neurotoxin","level":2,"score":0.7917188405990601},{"id":"https://openalex.org/C2778514916","wikidata":"https://www.wikidata.org/wiki/Q186242","display_name":"Norepinephrine","level":3,"score":0.7346811294555664},{"id":"https://openalex.org/C50610925","wikidata":"https://www.wikidata.org/wiki/Q1136816","display_name":"Habituation","level":2,"score":0.7003377079963684},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4940965473651886},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.42819488048553467},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.427432656288147},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3615536093711853},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2811368703842163},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24777069687843323},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.23520424962043762},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.14253383874893188}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:surface.syr.edu:psy_etd-1093","doi":null,"is_oa":false,"landing_page_url":"http://libezproxy.syr.edu/login?url=http://proquest.umi.com/pqdweb?did=732925681&sid=1&Fmt=2&clientId=3739&RQT=309&VName=PQD","pdf_url":null,"source":{"id":"https://openalex.org/S4306401700","display_name":"Syracuse University Libraries (Syracuse University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I70983195","host_organization_name":"Syracuse University","host_organization_lineage":["https://openalex.org/I70983195"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Psychology - Dissertations","raw_type":"text"},{"id":"mag:59302286","doi":null,"is_oa":false,"landing_page_url":"https://surface.syr.edu/psy_etd/99/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2031028242","https://openalex.org/W4389181001","https://openalex.org/W3041168307","https://openalex.org/W2026057574","https://openalex.org/W2063770546","https://openalex.org/W2089822005","https://openalex.org/W1985831018","https://openalex.org/W2072820017","https://openalex.org/W2025009628","https://openalex.org/W2041380137"],"abstract_inverted_index":{"Male":[0],"CD-1":[1],"mice":[2],"between":[3,141,260],"postnatal":[4],"days":[5,32],"60":[6],"and":[7,54,69,80,92,102,109,123,144,266],"90":[8],"were":[9,27,46,51,66,89,112],"injected":[10,53,68],"intraperitoneally":[11],"(i.p)":[12],"with":[13,166],"either":[14],"water":[15,52,67],"vehicle":[16],"(controls)":[17],"or":[18],"50$\\mu$g/g":[19],"of":[20,37,149,181,228,263,285,292,301,364],"the":[21,35,57,72,76,85,94,98,107,115,119,129,142,152,167,187,195,206,210,229,235,255,261,272,283,286,290,311,316],"norepinephrine":[22],"neurotoxin":[23],"N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine":[24],"(DSP-4).":[25],"They":[26],"tested":[28],"3":[29],"to":[30,56,71,114,124,151,245,288,306,315,326],"6":[31],"later":[33],"on":[34,60,75,84,97,106,118,128,172,194,242,332],"odors":[36,262,291],"adult":[38],"males":[39],"in":[40,137,162,205,219],"a":[41,81,103,125,134,159,178,199,216,264,293,320,327,340,343,349,362],"four-trial":[42],"habituation/dishabituation":[43],"paradigm.":[44],"There":[45],"four":[47,62],"groups:":[48],"group":[49,64,87,110,212,231,257,274,313],"CSS":[50,157],"exposed":[55,70,93,113,325],"same":[58,73,95],"male":[59,74,96,127],"all":[61,337],"trials;":[63],"CSN":[65,176,256],"first":[77,99,120,143,188,236],"three":[78,100,121,189,237],"trials":[79,101,122,238],"novel":[82,104,126,267,328],"one":[83,105,351],"fourth;":[86,108],"DSN":[88,211,273],"DSP-4":[90,278],"treated":[91],"D0-N":[111,230,312],"empty":[116],"apparatus":[117],"fourth.":[130],"All":[131],"groups":[132,338],"showed":[133,319,339],"significant":[135],"decline":[136],"screen":[138,163,183,220],"investigation":[139,164,169,184,226],"time":[140,165,170,185,222,227],"second":[145],"trials,":[146,190],"an":[147,296,333],"indication":[148],"habituation":[150],"overall":[153],"testing":[154,317],"environment.":[155],"Group":[156,175],"demonstrated":[158,177],"progressive":[160],"decrease":[161],"least":[168],"occurring":[171],"trial":[173,197,243,246],"4.":[174],"similar":[179],"pattern":[180],"diminishing":[182,193],"over":[186,234,348],"but":[191,239],"stopped":[192],"fourth":[196],"when":[198,324],"new":[200],"stimulus":[201],"animal":[202,268],"was":[203,303],"placed":[204],"cage.":[207],"Animals":[208],"from":[209,254,271,310],"did":[213],"not":[214,304],"demonstrate":[215],"quantitative":[217],"change":[218],"investigating":[221],"at":[223],"all.":[224],"Screen":[225],"decreased":[232],"progressively":[233],"increased":[240],"sharply":[241],"4":[244],"1":[247],"levels.":[248],"These":[249],"results":[250,356],"suggest":[251,357],"that":[252,358],"animals":[253,287,309],"could":[258,275],"distinguish":[259],"familiar":[265,294,344],"while":[269],"those":[270],"not.":[276],"Thus":[277],"treatment":[279],"may":[280],"have":[281],"impaired":[282],"ability":[284],"recognize":[289],"versus":[295],"unfamiliar":[297],"conspecific.":[298],"This":[299],"failure":[300],"recognition":[302],"due":[305],"anosmia":[307],"since":[308],"habituated":[314],"environment":[318],"strong":[321],"dishabituation":[322],"response":[323],"animal.":[329],"In":[330],"addition,":[331],"olfactory":[334],"preference":[335,341],"test,":[336],"for":[342],"botanical":[345],"odor":[346],"(hardwood)":[347],"nonfamiliar":[350],"(pine).":[352],"Taken":[353],"together,":[354],"these":[355],"central":[359],"NE":[360],"is":[361],"modulator":[363],"intermale":[365],"social":[366],"olfaction.":[367]},"counts_by_year":[],"updated_date":"2026-08-08T01:25:22.217667","created_date":"2016-06-24T00:00:00"}