{"id":"https://openalex.org/W592013643","doi":null,"title":"[Inflammatory bowel disease and pregnancy: clinical study of mutual influence, clinical course and treatment].","display_name":"[Inflammatory bowel disease and pregnancy: clinical study of mutual influence, clinical course and treatment].","publication_year":1999,"publication_date":"1999-03-01","ids":{"openalex":"https://openalex.org/W592013643","mag":"592013643","pmid":"https://pubmed.ncbi.nlm.nih.gov/10214074"},"language":"ja","primary_location":{"id":"pmid:10214074","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10214074","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025899019","display_name":"Tatsuo Oriuchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T Oriuchi","raw_affiliation_strings":["Third Department of Internal Medicine, Tohoku University School of Medicine","Third Dept. of Internal Medicine, Tohoku University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Third Department of Internal Medicine, Tohoku University School of Medicine","institution_ids":["https://openalex.org/I201537933"]},{"raw_affiliation_string":"Third Dept. of Internal Medicine, Tohoku University School of Medicine","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034905709","display_name":"Nobuo Hiwatashi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"N Hiwatashi","raw_affiliation_strings":["\u6771\u5317\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6771\u5317\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038802136","display_name":"Y Katsurashima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y Katsurashima","raw_affiliation_strings":["\u6771\u5317\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6771\u5317\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080231158","display_name":"Mitsunori Noguchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M Noguchi","raw_affiliation_strings":["\u6771\u5317\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6771\u5317\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043020113","display_name":"Yoshitaka Kinouchi","orcid":"https://orcid.org/0000-0002-3368-8855","observed_orcids":["https://orcid.org/0000-0002-3368-8855"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Kinouchi","raw_affiliation_strings":["Division of Research in Student Support"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Research in Student Support","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110335478","display_name":"Takayoshi Toyota","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T Toyota","raw_affiliation_strings":["\u6771\u5317\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6771\u5317\u5927\u5b66\u533b\u5b66\u90e8\u7b2c3\u5185\u79d1","institution_ids":["https://openalex.org/I201537933"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"96","issue":"3","first_page":"266","last_page":"72"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12230","display_name":"Cardiovascular Issues in Pregnancy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.9950000047683716},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/ulcerative-colitis","display_name":"ulcerative colitis","score":1.0},{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":1.0},{"id":"https://openalex.org/keywords/recurrence","display_name":"recurrence","score":0.7599999904632568},{"id":"https://openalex.org/keywords/remission","display_name":"remission","score":0.5410000085830688},{"id":"https://openalex.org/keywords/sulfasalazine","display_name":"sulfasalazine","score":0.8619999885559082},{"id":"https://openalex.org/keywords/corticosteroids","display_name":"corticosteroids","score":0.9639999866485596},{"id":"https://openalex.org/keywords/fetal-effects","display_name":"fetal effects","score":0.5609999895095825},{"id":"https://openalex.org/keywords/pregnancy-outcomes","display_name":"pregnancy outcomes","score":0.34200000762939453}],"concepts":[{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.9358981847763062},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8135974407196045},{"id":"https://openalex.org/C2780479503","wikidata":"https://www.wikidata.org/wiki/Q1477","display_name":"Ulcerative colitis","level":3,"score":0.7961148023605347},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6199672818183899},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.6133396625518799},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.5959094166755676},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.5058934092521667},{"id":"https://openalex.org/C2779280984","wikidata":"https://www.wikidata.org/wiki/Q1472","display_name":"Crohn's disease","level":3,"score":0.4369164705276489},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3179395794868469},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003093","descriptor_name":"Colitis, Ulcerative","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003093","descriptor_name":"Colitis, Ulcerative","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D003424","descriptor_name":"Crohn Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D003424","descriptor_name":"Crohn Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005765","descriptor_name":"Gastrointestinal Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D011256","descriptor_name":"Pregnancy Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012074","descriptor_name":"Remission Induction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012460","descriptor_name":"Sulfasalazine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:10214074","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10214074","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology","raw_type":"English Abstract"},{"id":"mag:592013643","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10214074","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W10339549","https://openalex.org/W47974481","https://openalex.org/W144861187","https://openalex.org/W188945809","https://openalex.org/W1919509010","https://openalex.org/W1957642485","https://openalex.org/W1979456617","https://openalex.org/W1990448536","https://openalex.org/W2011848078","https://openalex.org/W2012618527","https://openalex.org/W2030424235","https://openalex.org/W2042820492","https://openalex.org/W2044434730","https://openalex.org/W2068247800","https://openalex.org/W2082764205","https://openalex.org/W2114209874","https://openalex.org/W2121146612","https://openalex.org/W2765148543"],"related_works":["https://openalex.org/W2427612714","https://openalex.org/W278004279","https://openalex.org/W2411962645","https://openalex.org/W1988079987","https://openalex.org/W2044434730","https://openalex.org/W2068971044","https://openalex.org/W1963498335","https://openalex.org/W2791288548","https://openalex.org/W1919509010","https://openalex.org/W1604770328"],"abstract_inverted_index":{"We":[0,26],"studied":[1],"the":[2,36,71,99,128,145,148],"clinical":[3],"courses":[4],"of":[5,38,58,73,84,101,118,130,150],"70":[6],"pregnancies":[7,17],"in":[8,18],"47":[9],"women":[10,20],"with":[11,21,43,67],"ulcerative":[12],"colitis":[13],"(UC)":[14],"and":[15,60,138,147],"18":[16],"12":[19],"Crohn's":[22],"disease":[23],"(CD)":[24],"retrospectively.":[25],"concluded":[27],"as":[28],"follows.":[29],"1.":[30],"Pregnancy":[31],"has":[32,94,124,141],"less":[33,56,142],"influence":[34,97,143],"on":[35,98,127,144],"course":[37,100,129,149],"UC.":[39],"2.":[40],"The":[41,65,80],"patients":[42,66,81],"UC":[44,69,85,93],"who":[45],"kept":[46],"remission":[47],"for":[48],"more":[49],"than":[50],"1":[51],"year":[52],"before":[53],"conception":[54,74],"have":[55],"risk":[57],"relapse":[59],"severity":[61],"during":[62,78,87,122],"pregnancy.":[63,79,151],"3.":[64],"active":[68,105],"at":[70],"time":[72],"tend":[75,89],"to":[76,90],"worsen":[77],"whose":[82],"onset":[83],"is":[86,109,134],"pregnancy":[88,102,113,123],"worsen.":[91],"4.":[92],"a":[95,115],"little":[96,125],"except":[103],"severe":[104],"disease.":[106],"5.":[107],"It":[108],"not":[110],"obtained":[111],"that":[112],"becomes":[114],"relapsing":[116],"factor":[117],"CD.":[119],"6.":[120],"CD":[121],"influences":[126],"pregnancy,":[131],"if":[132],"it":[133],"remitted.":[135],"7.":[136],"Salazosulfapyridine":[137],"corticosteroids":[139],"therapy":[140],"fetus":[146]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}