{"id":"https://openalex.org/W591533299","doi":null,"title":"Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management.","display_name":"Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management.","publication_year":2015,"publication_date":"2015-06-01","ids":{"openalex":"https://openalex.org/W591533299","mag":"591533299","pmid":"https://pubmed.ncbi.nlm.nih.gov/26029015","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4445438"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4445438","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4445438","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4445438","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022082443","display_name":"Alexander Marzuka-Alcal\u00e1","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander G Marzuka","raw_affiliation_strings":["Department of Dermatology, Yale School of Medicine, New Haven, Connecticut ; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Yale School of Medicine, New Haven, Connecticut ; Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018491048","display_name":"Samuel E Book","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel E Book","raw_affiliation_strings":["Department of Dermatology, Yale School of Medicine, New Haven, Connecticut"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Yale School of Medicine, New Haven, Connecticut","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":null,"apc_paid":null,"fwci":23.8371,"has_fulltext":false,"cited_by_count":382,"citation_normalized_percentile":{"value":0.99763194,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"88","issue":"2","first_page":"167","last_page":"79"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12009","display_name":"Hedgehog Signaling Pathway Studies","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11868","display_name":"Cancer and Skin Lesions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/basal-cell-carcinoma","display_name":"basal cell carcinoma","score":1.0},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.8130000233650208},{"id":"https://openalex.org/keywords/epidemiology","display_name":"epidemiology","score":0.9829999804496765},{"id":"https://openalex.org/keywords/clinical-characteristics","display_name":"clinical features","score":0.9760000109672546},{"id":"https://openalex.org/keywords/diagnosis","display_name":"diagnosis","score":0.9819999933242798},{"id":"https://openalex.org/keywords/histopathology","display_name":"histopathology","score":1.0},{"id":"https://openalex.org/keywords/treatment","display_name":"treatment","score":0.44699999690055847},{"id":"https://openalex.org/keywords/risk-of-recurrence","display_name":"recurrence risk","score":0.640999972820282},{"id":"https://openalex.org/keywords/tissue-preservation","display_name":"tissue preservation","score":0.9089999794960022},{"id":"https://openalex.org/keywords/sun-exposure","display_name":"sun exposure","score":0.7889999747276306},{"id":"https://openalex.org/keywords/hedgehog-signaling","display_name":"Hedgehog signaling","score":0.7020000219345093},{"id":"https://openalex.org/keywords/skin-cancer","display_name":"skin cancer","score":0.7559999823570251}],"concepts":[{"id":"https://openalex.org/C2778804307","wikidata":"https://www.wikidata.org/wiki/Q809758","display_name":"Basal cell carcinoma","level":3,"score":0.8649352788925171},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.820549726486206},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.6444602608680725},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.6003862619400024},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5527721643447876},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5189163684844971},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5105172395706177},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.42348992824554443},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3896465599536896},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3530207872390747},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.30906039476394653},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23308086395263672}],"mesh":[{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002280","descriptor_name":"Basal Cell Carcinoma","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D002280","descriptor_name":"Basal Cell Carcinoma","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D002280","descriptor_name":"Basal Cell Carcinoma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003646","descriptor_name":"Debridement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004781","descriptor_name":"Environmental Exposure","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D013472","descriptor_name":"Sunlight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015580","descriptor_name":"Mohs Surgery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015995","descriptor_name":"Prevalence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019090","descriptor_name":"Case Management","qualifier_ui":"Q000458","qualifier_name":"organization & administration","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:4445438","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4445438","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},{"id":"pmid:26029015","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26029015","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Yale journal of biology and medicine","raw_type":"Journal Article"},{"id":"mag:591533299","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26029015","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4445438","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4445438","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yale J Biol Med","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":97,"referenced_works":["https://openalex.org/W1533521720","https://openalex.org/W1571649602","https://openalex.org/W1581362113","https://openalex.org/W1582239534","https://openalex.org/W1582375825","https://openalex.org/W1594815607","https://openalex.org/W1611326883","https://openalex.org/W1857531999","https://openalex.org/W1964687566","https://openalex.org/W1965405304","https://openalex.org/W1968548603","https://openalex.org/W1970911113","https://openalex.org/W1970960957","https://openalex.org/W1975048282","https://openalex.org/W1976690801","https://openalex.org/W1982009692","https://openalex.org/W1983103562","https://openalex.org/W1983951732","https://openalex.org/W1986404157","https://openalex.org/W1987430515","https://openalex.org/W1992921643","https://openalex.org/W1994620081","https://openalex.org/W1995298955","https://openalex.org/W1998092199","https://openalex.org/W2005024028","https://openalex.org/W2005341482","https://openalex.org/W2005457683","https://openalex.org/W2006290765","https://openalex.org/W2006455323","https://openalex.org/W2011342967","https://openalex.org/W2013921573","https://openalex.org/W2017194589","https://openalex.org/W2018724029","https://openalex.org/W2021354108","https://openalex.org/W2022005853","https://openalex.org/W2023123308","https://openalex.org/W2031377991","https://openalex.org/W2032275493","https://openalex.org/W2036174002","https://openalex.org/W2037562514","https://openalex.org/W2037660872","https://openalex.org/W2044616474","https://openalex.org/W2053141040","https://openalex.org/W2053164277","https://openalex.org/W2054947389","https://openalex.org/W2055233296","https://openalex.org/W2057380783","https://openalex.org/W2066585913","https://openalex.org/W2073356001","https://openalex.org/W2080757920","https://openalex.org/W2083513345","https://openalex.org/W2083610541","https://openalex.org/W2086544999","https://openalex.org/W2089589144","https://openalex.org/W2090828704","https://openalex.org/W2090875070","https://openalex.org/W2091154154","https://openalex.org/W2092742813","https://openalex.org/W2093358903","https://openalex.org/W2093659327","https://openalex.org/W2096207257","https://openalex.org/W2096231077","https://openalex.org/W2097399545","https://openalex.org/W2098231073","https://openalex.org/W2101616608","https://openalex.org/W2106039705","https://openalex.org/W2115947121","https://openalex.org/W2117943867","https://openalex.org/W2118315567","https://openalex.org/W2122888213","https://openalex.org/W2123600514","https://openalex.org/W2126090166","https://openalex.org/W2127001212","https://openalex.org/W2131131624","https://openalex.org/W2133408276","https://openalex.org/W2135825792","https://openalex.org/W2138530019","https://openalex.org/W2140619393","https://openalex.org/W2143017568","https://openalex.org/W2145561110","https://openalex.org/W2146333887","https://openalex.org/W2146613985","https://openalex.org/W2146657218","https://openalex.org/W2147133104","https://openalex.org/W2148779454","https://openalex.org/W2161786056","https://openalex.org/W2162489686","https://openalex.org/W2165469800","https://openalex.org/W2165904438","https://openalex.org/W2169929967","https://openalex.org/W2170888506","https://openalex.org/W2171301660","https://openalex.org/W2215457787","https://openalex.org/W4237828098","https://openalex.org/W4242031217","https://openalex.org/W4243471449","https://openalex.org/W4249395580"],"related_works":["https://openalex.org/W3198026075","https://openalex.org/W3094494304","https://openalex.org/W3184633037","https://openalex.org/W2323026075","https://openalex.org/W4237505611","https://openalex.org/W4242759765","https://openalex.org/W2902474170","https://openalex.org/W2755269207","https://openalex.org/W3086868714","https://openalex.org/W2914685428"],"abstract_inverted_index":{"Basal":[0],"cell":[1],"carcinoma":[2],"(BCC)":[3],"is":[4,12],"the":[5,13],"most":[6,14],"common":[7],"malignancy.":[8],"Exposure":[9],"to":[10],"sunlight":[11],"important":[15],"risk":[16],"factor.":[17],"Most,":[18],"if":[19],"not":[20],"all,":[21],"cases":[22],"of":[23,31,43,50,61],"BCC":[24,62],"demonstrate":[25],"overactive":[26],"Hedgehog":[27],"signaling.":[28],"A":[29],"variety":[30],"treatment":[32],"modalities":[33],"exist":[34],"and":[35,48,59],"are":[36],"selected":[37],"based":[38],"on":[39],"recurrence":[40],"risk,":[41],"importance":[42],"tissue":[44],"preservation,":[45],"patient":[46],"preference,":[47],"extent":[49],"disease.":[51],"The":[52],"pathogenesis,":[53],"epidemiology,":[54],"clinical":[55],"features,":[56],"diagnosis,":[57],"histopathology,":[58],"management":[60],"will":[63],"be":[64],"discussed":[65],"in":[66],"this":[67],"review.":[68]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":36},{"year":2024,"cited_by_count":37},{"year":2023,"cited_by_count":45},{"year":2022,"cited_by_count":47},{"year":2021,"cited_by_count":68},{"year":2020,"cited_by_count":40},{"year":2019,"cited_by_count":33},{"year":2018,"cited_by_count":32},{"year":2017,"cited_by_count":19},{"year":2016,"cited_by_count":15},{"year":2015,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}