{"id":"https://openalex.org/W59094656","doi":null,"title":"[Laser inducing mucosal fibrosis for preventing recurrence of esophageal varices].","display_name":"[Laser inducing mucosal fibrosis for preventing recurrence of esophageal varices].","publication_year":2004,"publication_date":"2004-12-22","ids":{"openalex":"https://openalex.org/W59094656","mag":"59094656","pmid":"https://pubmed.ncbi.nlm.nih.gov/15733486"},"language":"zh","primary_location":{"id":"pmid:15733486","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15733486","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhonghua wai ke za zhi [Chinese journal of surgery]","raw_type":"Clinical Trial"},"parent_works":[],"lineage":["https://openalex.org/W59094656"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077243399","display_name":"LU Huan-yuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210156904","display_name":"Third Xiangya Hospital","ror":"https://ror.org/05akvb491","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156904"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huan-yuan Lu","raw_affiliation_strings":["Department of General Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China. Luhuanyuan@hotmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China. Luhuanyuan@hotmail.com","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210156904"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xun-yang Liu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xun-yang Liu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101449793","display_name":"Feizhou Huang","orcid":"https://orcid.org/0000-0002-4289-1230","observed_orcids":["https://orcid.org/0000-0002-4289-1230"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fei-zhou Huang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110520651","display_name":"Wanpin Nie","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Wan-pin Nie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Shu-ping Ren","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shu-ping Ren","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5049544758","display_name":"Huang Rang-lang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rang-lang Huang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.00584899,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":92},"biblio":{"volume":"42","issue":"24","first_page":"1513","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10337","display_name":"Liver Disease and Transplantation","score":0.9794999957084656,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/esophageal-varices","display_name":"esophageal varices","score":0.9779999852180481},{"id":"https://openalex.org/keywords/diode-laser-therapy","display_name":"diode laser therapy","score":0.7950000166893005},{"id":"https://openalex.org/keywords/endoscopic-variceal-ligation","display_name":"endoscopic variceal ligation","score":0.8610000014305115},{"id":"https://openalex.org/keywords/portal-hypertension","display_name":"portal hypertension","score":0.7509999871253967}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9439728260040283},{"id":"https://openalex.org/C2777595160","wikidata":"https://www.wikidata.org/wiki/Q298278","display_name":"Esophageal varices","level":4,"score":0.7195456624031067},{"id":"https://openalex.org/C179437574","wikidata":"https://www.wikidata.org/wiki/Q15089798","display_name":"Ligation","level":2,"score":0.6359115839004517},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.6225314736366272},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.6076874732971191},{"id":"https://openalex.org/C2778012290","wikidata":"https://www.wikidata.org/wiki/Q2624485","display_name":"Varices","level":3,"score":0.5125429630279541},{"id":"https://openalex.org/C2781065829","wikidata":"https://www.wikidata.org/wiki/Q905662","display_name":"Indocyanine green","level":2,"score":0.49871134757995605},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4535674452781677},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4504207670688629},{"id":"https://openalex.org/C2778451229","wikidata":"https://www.wikidata.org/wiki/Q212809","display_name":"Endoscopy","level":2,"score":0.4496482014656067},{"id":"https://openalex.org/C2778808290","wikidata":"https://www.wikidata.org/wiki/Q124604","display_name":"Portal hypertension","level":3,"score":0.29681646823883057},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.2728998064994812}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004932","descriptor_name":"Esophageal and Gastric Varices","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D004932","descriptor_name":"Esophageal and Gastric Varices","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D004945","descriptor_name":"Esophagoscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004947","descriptor_name":"Esophagus","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005355","descriptor_name":"Fibrosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008026","descriptor_name":"Ligation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009092","descriptor_name":"Mucous Membrane","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D017075","descriptor_name":"Laser Coagulation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055502","descriptor_name":"Secondary Prevention","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:15733486","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15733486","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhonghua wai ke za zhi [Chinese journal of surgery]","raw_type":"Clinical Trial"},{"id":"mag:59094656","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15733486","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2013788442","https://openalex.org/W7146496190","https://openalex.org/W7208565446","https://openalex.org/W2357467428","https://openalex.org/W2373429591","https://openalex.org/W2139272572","https://openalex.org/W2409938760","https://openalex.org/W1999235354","https://openalex.org/W2912378999","https://openalex.org/W2064023158"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"investigate":[2],"the":[3,68,71,126,134],"prevention":[4],"of":[5,163],"esophageal":[6,12,22,111,164],"varices":[7,23,27],"recurrence":[8,128,162],"by":[9,25,91],"laser":[10,48,61,117,153],"inducing":[11,154],"mucosal":[13],"fibrosis.":[14],"METHODS:":[15],"Our":[16,149],"study":[17,150],"included":[18,39],"42":[19],"patients":[20],"after":[21,116],"eradicated":[24],"endoscopic":[26],"ligation,":[28],"and":[29,50,159],"they":[30],"were":[31,88],"divided":[32],"into":[33],"2":[34],"groups":[35],"randomly,":[36],"each":[37],"group":[38,43,80],"21":[40],"patients.":[41],"One":[42],"was":[44,56,65,81,102,130],"assigned":[45],"to":[46,67,74],"received":[47],"treatment,":[49],"indocyanine":[51],"green":[52],"solution":[53],"(1":[54],"mg/ml)":[55],"injected":[57],"submucosally,":[58],"a":[59],"diode":[60],"(power":[62],"10":[63],"watts)":[64],"applied":[66],"surface":[69],"from":[70],"esophagogastric":[72],"junction":[73],"5":[75],"cm":[76],"above":[77],"it.":[78],"Another":[79],"controlling":[82],"without":[83,105],"any":[84,106],"treatments.":[85],"All":[86],"patient":[87],"followed":[89],"up":[90],"endoscopy":[92],"every":[93],"3":[94],"months":[95,123],"until":[96],"12":[97,122],"months.":[98],"RESULTS:":[99],"Laser":[100],"irradiation":[101],"performed":[103],"safely":[104,158],"major":[107],"complications.":[108],"And":[109],"lower":[110,132],"mucosa":[112],"produced":[113],"fibrosis":[114,156],"widely":[115],"irradiated":[118],"1":[119],"month.":[120],"After":[121],"follow":[124],"up,":[125],"cumulative":[127],"rate":[129],"significantly":[131],"than":[133],"control":[135],"group,":[136],"14%":[137],"(3/21)":[138],"vs":[139],"43%":[140],"(9/21)":[141],"(chi(2)":[142],"=":[143],"4.20,":[144],"P":[145],"<":[146],"0.05).":[147],"CONCLUSIONS:":[148],"indicates":[151],"that":[152],"mucous":[155],"is":[157],"can":[160],"prevent":[161],"varices.":[165]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}