{"id":"https://openalex.org/W58819829","doi":null,"title":"Veno-occlusive disease in pediatric patients receiving actinomycin D and vincristine only for the treatment of rhabdomyosarcoma.","display_name":"Veno-occlusive disease in pediatric patients receiving actinomycin D and vincristine only for the treatment of rhabdomyosarcoma.","publication_year":2004,"publication_date":"2004-12-01","ids":{"openalex":"https://openalex.org/W58819829","mag":"58819829","pmid":"https://pubmed.ncbi.nlm.nih.gov/15591910"},"language":"en","primary_location":{"id":"pmid:15591910","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15591910","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pediatric hematology/oncology","raw_type":"Case Reports"},"parent_works":[],"lineage":["https://openalex.org/W58819829"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018962418","display_name":"Maria Luisa Sulis","orcid":"https://orcid.org/0000-0003-2110-0193","observed_orcids":["https://orcid.org/0000-0003-2110-0193"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria Luisa Sulis","raw_affiliation_strings":["Division of Pediatric Oncology, Children's Hospital of New York, Columbia University, 161 Fort Washington Avenue, Irving Pavilion 7, New York, NY 10032, USA. mls95@columbia.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Oncology, Children's Hospital of New York, Columbia University, 161 Fort Washington Avenue, Irving Pavilion 7, New York, NY 10032, USA. mls95@columbia.edu","institution_ids":["https://openalex.org/I2799503643","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091007371","display_name":"Olga Bessmertny","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Olga Bessmertny","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006409660","display_name":"Linda Granowetter","orcid":"https://orcid.org/0000-0002-2399-9107","observed_orcids":["https://orcid.org/0000-0002-2399-9107"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Linda Granowetter","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088683585","display_name":"Michael A. Weiner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael Weiner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5089358491","display_name":"Kara M. Kelly","orcid":"https://orcid.org/0000-0003-1473-3937","observed_orcids":["https://orcid.org/0000-0003-1473-3937"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kara M Kelly","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9189,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.73985957,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"26","issue":"12","first_page":"843","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.6664999723434448,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.6664999723434448,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12937","display_name":"Chemotherapy-related skin toxicity","score":0.053300000727176666,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.02590000070631504,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatic-veno-occlusive-disease","display_name":"veno-occlusive disease","score":0.9330000281333923},{"id":"https://openalex.org/keywords/rhabdomyosarcoma","display_name":"rhabdomyosarcoma","score":0.9860000014305115},{"id":"https://openalex.org/keywords/dactinomycin","display_name":"actinomycin D","score":0.9869999885559082},{"id":"https://openalex.org/keywords/vincristine","display_name":"vincristine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/pediatric-chemotherapy","display_name":"pediatric chemotherapy","score":0.7369999885559082},{"id":"https://openalex.org/keywords/chemotherapy-toxicity","display_name":"chemotherapy toxicity","score":0.48500001430511475}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9436604976654053},{"id":"https://openalex.org/C2779429289","wikidata":"https://www.wikidata.org/wiki/Q408977","display_name":"Vincristine","level":4,"score":0.8867837190628052},{"id":"https://openalex.org/C2780844630","wikidata":"https://www.wikidata.org/wiki/Q1898141","display_name":"Rhabdomyosarcoma","level":3,"score":0.8805424571037292},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.7528785467147827},{"id":"https://openalex.org/C2775999222","wikidata":"https://www.wikidata.org/wiki/Q756289","display_name":"Wilms' tumor","level":2,"score":0.7033588886260986},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.6601107120513916},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4783448874950409},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.45432037115097046},{"id":"https://openalex.org/C2778670039","wikidata":"https://www.wikidata.org/wiki/Q414004","display_name":"Nitrogen mustard","level":4,"score":0.44575759768486023},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4166557192802429},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3228238523006439},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.23942387104034424},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.22472018003463745}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000971","descriptor_name":"Antineoplastic Combined Chemotherapy Protocols","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003609","descriptor_name":"Dactinomycin","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D003609","descriptor_name":"Dactinomycin","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006504","descriptor_name":"Hepatic Veno-Occlusive Disease","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012208","descriptor_name":"Rhabdomyosarcoma","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D014750","descriptor_name":"Vincristine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014750","descriptor_name":"Vincristine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:15591910","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15591910","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pediatric hematology/oncology","raw_type":"Case Reports"},{"id":"mag:58819829","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15591910","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1546367566","https://openalex.org/W1969216286","https://openalex.org/W2013287047","https://openalex.org/W2114654164","https://openalex.org/W2412821583","https://openalex.org/W2013698888","https://openalex.org/W2048767635","https://openalex.org/W2419367814","https://openalex.org/W2117062808","https://openalex.org/W2434540755"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Veno-occlusive":[1],"disease":[2],"(VOD)":[3],"following":[4],"standard":[5],"chemotherapy":[6,170],"has":[7],"been":[8,54],"reported":[9],"in":[10,37,69,143],"patients":[11,38,50,70,130,144],"receiving":[12],"vincristine":[13,75,150],"actinomycin":[14,35,77,118,152],"D,":[15],"and":[16,24,30,42,76,120,151,167],"cyclophosphamide":[17,47],"for":[18,59,83],"the":[19,43,56,84,95,127,163],"treatment":[20],"of":[21,32,34,46,67,86,97,101,117,135,169],"Wilms":[22,40],"tumor":[23,41],"more":[25],"rarely":[26],"rhabdomyosarcoma.":[27],"The":[28,62],"dose":[29,45],"schedule":[31],"administration":[33],"D":[36,78,119,153],"with":[39,51,71,74,132,145,149],"increased":[44],"administered":[48],"to":[49,114,123],"rhabdomyosarcoma":[52,72,147],"have":[53],"considered":[55],"likely":[57],"etiology":[58],"VOD.":[60],"METHODS:":[61],"authors":[63],"report":[64],"four":[65,115],"cases":[66],"VOD":[68,87,90,110,140,157],"treated":[73,148],"only.":[79],"No":[80],"risk":[81],"factors":[82],"development":[85],"were":[88],"identified.":[89],"was":[91],"diagnosed":[92],"clinically":[93],"by":[94,106],"presence":[96],"at":[98],"least":[99],"two":[100,113],"three":[102],"findings":[103],"as":[104],"defined":[105],"McDonald":[107],"et":[108],"al.":[109],"occurred":[111],"after":[112,126],"doses":[116],"approximately":[121],"7":[122],"14":[124],"days":[125],"dose.":[128],"All":[129],"recovered":[131],"no":[133],"evidence":[134],"permanent":[136],"hepatic":[137],"damage.":[138],"CONCLUSIONS:":[139],"can":[141],"occur":[142],"\"low-stage\"":[146],"alone.":[154],"Although":[155],"chemotherapy-related":[156],"is":[158,165,171],"a":[159],"potentially":[160],"severe":[161],"disease,":[162],"outcome":[164],"good":[166],"resumption":[168],"well":[172],"tolerated.":[173]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}