{"id":"https://openalex.org/W58625472","doi":"https://doi.org/10.1007/978-1-4020-9464-4_7","title":"Schizophrenia Endophenotypes as Treatment Targets","display_name":"Schizophrenia Endophenotypes as Treatment Targets","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W58625472","doi":"https://doi.org/10.1007/978-1-4020-9464-4_7","mag":"58625472"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4020-9464-4_7","doi":"https://doi.org/10.1007/978-1-4020-9464-4_7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4020-9464-4_7","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W1266552979","display_name":"The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047021203","display_name":"Stephen I. Deutsch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephen I. Deutsch","raw_affiliation_strings":["Department of Psychiatry, Georgetown University School of Medicine, Washington, USA","Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Georgetown University School of Medicine, Washington, USA","institution_ids":["https://openalex.org/I184565670"]},{"raw_affiliation_string":"Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084542477","display_name":"Barbara L. Schwartz","orcid":"https://orcid.org/0009-0005-4653-5777","observed_orcids":["https://orcid.org/0009-0005-4653-5777"]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barbara L. Schwartz","raw_affiliation_strings":["Department of Psychiatry, Georgetown University School of Medicine, Washington, USA","Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Georgetown University School of Medicine, Washington, USA","institution_ids":["https://openalex.org/I184565670"]},{"raw_affiliation_string":"Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048409402","display_name":"Richard B. Rosse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard B. Rosse","raw_affiliation_strings":["Department of Psychiatry, Georgetown University School of Medicine, Washington, USA","Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Georgetown University School of Medicine, Washington, USA","institution_ids":["https://openalex.org/I184565670"]},{"raw_affiliation_string":"Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014062802","display_name":"John P. Mastropaolo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John Mastropaolo","raw_affiliation_strings":["Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045026911","display_name":"Ayman H. Fanous","orcid":"https://orcid.org/0000-0002-5152-9989","observed_orcids":["https://orcid.org/0000-0002-5152-9989","https://orcid.org/0009-0009-8121-9111"]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ayman H. Fanous","raw_affiliation_strings":["Department of Psychiatry, Georgetown University School of Medicine, Washington, USA","Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Georgetown University School of Medicine, Washington, USA","institution_ids":["https://openalex.org/I184565670"]},{"raw_affiliation_string":"Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063898483","display_name":"Abraham Weizman","orcid":"https://orcid.org/0000-0002-9765-8938","observed_orcids":["https://orcid.org/0000-0002-9765-8938"]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Abraham Weizman","raw_affiliation_strings":["Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, Israel","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028433506","display_name":"Jessica A. Burket","orcid":"https://orcid.org/0000-0002-1260-4747","observed_orcids":["https://orcid.org/0000-0002-1260-4747"]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica A. Burket","raw_affiliation_strings":["Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037776902","display_name":"Brooke L. Gaskins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brooke L. Gaskins","raw_affiliation_strings":["Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Veterans Affairs Medical Center, Mental Health Service Line, Washington, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5047021203"],"corresponding_institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I184565670","https://openalex.org/I2799886695"],"apc_list":null,"apc_paid":null,"fwci":3.2824,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.91038295,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"113","last_page":"122"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12308","display_name":"Mental Health and Psychiatry","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.8050000071525574},{"id":"https://openalex.org/keywords/endophenotypes","display_name":"endophenotypes","score":0.9819999933242798},{"id":"https://openalex.org/keywords/gene-environment-interaction","display_name":"gene-environment interaction","score":0.75},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.6110000014305115},{"id":"https://openalex.org/keywords/schizophrenia-spectrum-disorders","display_name":"schizophrenia spectrum disorders","score":0.6290000081062317},{"id":"https://openalex.org/keywords/schizotypy","display_name":"schizotypy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/pharmacotherapy-targets","display_name":"pharmacotherapy targets","score":0.5860000252723694},{"id":"https://openalex.org/keywords/chromosome-15","display_name":"chromosome 15","score":0.9300000071525574},{"id":"https://openalex.org/keywords/treatment-resistant-schizophrenia","display_name":"treatment-resistant schizophrenia","score":0.4790000021457672},{"id":"https://openalex.org/keywords/socialization-deficits","display_name":"socialization deficits","score":0.40400001406669617},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.8500000238418579},{"id":"https://openalex.org/keywords/family-based-genetic-study","display_name":"family-based genetic study","score":0.43799999356269836},{"id":"https://openalex.org/keywords/schizophrenia-diagnosis","display_name":"schizophrenia diagnosis","score":0.3400000035762787}],"concepts":[{"id":"https://openalex.org/C187869287","wikidata":"https://www.wikidata.org/wiki/Q2032061","display_name":"Endophenotype","level":3,"score":0.994931697845459},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.6400977373123169},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5893946886062622},{"id":"https://openalex.org/C2780325297","wikidata":"https://www.wikidata.org/wiki/Q834047","display_name":"Schizoaffective disorder","level":3,"score":0.5095877647399902},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.49440646171569824},{"id":"https://openalex.org/C3018432486","wikidata":"https://www.wikidata.org/wiki/Q7575316","display_name":"Schizophrenia spectrum","level":3,"score":0.4477194547653198},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4436286687850952},{"id":"https://openalex.org/C2777154362","wikidata":"https://www.wikidata.org/wiki/Q7575316","display_name":"Spectrum disorder","level":2,"score":0.42015784978866577},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.3923020362854004},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3496153652667999},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.2872167229652405}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4020-9464-4_7","doi":"https://doi.org/10.1007/978-1-4020-9464-4_7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4020-9464-4_7","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.49000000953674316,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W147972831","https://openalex.org/W1531750674","https://openalex.org/W1532317254","https://openalex.org/W1963979286","https://openalex.org/W1987336202","https://openalex.org/W2014683164","https://openalex.org/W2027977900","https://openalex.org/W2028562300","https://openalex.org/W2029277771","https://openalex.org/W2043189970","https://openalex.org/W2047877800","https://openalex.org/W2083540742","https://openalex.org/W2099058526","https://openalex.org/W2108229432","https://openalex.org/W2108603403","https://openalex.org/W2116139029","https://openalex.org/W2124267752","https://openalex.org/W2131602794","https://openalex.org/W2131612765","https://openalex.org/W2145178659","https://openalex.org/W2157669798","https://openalex.org/W2158225568","https://openalex.org/W2162931666","https://openalex.org/W2164562866","https://openalex.org/W2164713150","https://openalex.org/W2168327895","https://openalex.org/W2185181443","https://openalex.org/W2259707068"],"related_works":["https://openalex.org/W2157669798","https://openalex.org/W2145178659","https://openalex.org/W7097095928","https://openalex.org/W1546698346","https://openalex.org/W76341706","https://openalex.org/W2367761793","https://openalex.org/W2415221507","https://openalex.org/W2012833324","https://openalex.org/W127002930","https://openalex.org/W2783288077"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}